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Items: 1 to 50 of 59

1.

Conserved Critical Evolutionary Gene Structures in Orthologs.

Fuertes MA, Rodrigo JR, Alonso C.

J Mol Evol. 2019 Apr;87(2-3):93-105. doi: 10.1007/s00239-019-09889-1. Epub 2019 Feb 28.

PMID:
30815710
2.

Structural Analysis of a Temperature-Induced Transition in a Viral Capsid Probed by HDX-MS.

van de Waterbeemd M, Llauró A, Snijder J, Valbuena A, Rodríguez-Huete A, Fuertes MA, de Pablo PJ, Mateu MG, Heck AJR.

Biophys J. 2017 Mar 28;112(6):1157-1165. doi: 10.1016/j.bpj.2017.02.003.

3.

Imaging and Quantitation of a Succession of Transient Intermediates Reveal the Reversible Self-Assembly Pathway of a Simple Icosahedral Virus Capsid.

Medrano M, Fuertes MÁ, Valbuena A, Carrillo PJ, Rodríguez-Huete A, Mateu MG.

J Am Chem Soc. 2016 Nov 30;138(47):15385-15396. Epub 2016 Nov 18.

PMID:
27933931
4.

A Method for the Annotation of Functional Similarities of Coding DNA Sequences: the Case of a Populated Cluster of Transmembrane Proteins.

Fuertes MA, Rodrigo JR, Alonso C.

J Mol Evol. 2017 Jan;84(1):29-38. doi: 10.1007/s00239-016-9763-7. Epub 2016 Nov 3.

PMID:
27812751
5.

Do Intron and Coding Sequences of Some Human-Mouse Orthologs Evolve as a Single Unit?

Fuertes MA, Rodrigo JR, Alonso C.

J Mol Evol. 2016 Jun;82(6):247-50. doi: 10.1007/s00239-016-9746-8. Epub 2016 May 24.

PMID:
27220874
6.

Decrease in coccolithophore calcification and CO2 since the middle Miocene.

Bolton CT, Hernández-Sánchez MT, Fuertes MÁ, González-Lemos S, Abrevaya L, Mendez-Vicente A, Flores JA, Probert I, Giosan L, Johnson J, Stoll HM.

Nat Commun. 2016 Jan 14;7:10284. doi: 10.1038/ncomms10284.

7.

Mixed Connective Tissue Disease in a Patient With Castleman Disease and Hodgkin Lymphoma: Excellent Clinical Response to Rituximab.

Gracia-Cazaña T, Delgado-Beltrán C, Concellón MA, Fuertes MA.

Actas Dermosifiliogr. 2015 Dec;106(10):843-6. doi: 10.1016/j.ad.2015.03.017. Epub 2015 Jul 29. English, Spanish. No abstract available.

PMID:
26232308
8.

Biophysical analysis of the MHR motif in folding and domain swapping of the HIV capsid protein C-terminal domain.

Bocanegra R, Fuertes MÁ, Rodríguez-Huete A, Neira JL, Mateu MG.

Biophys J. 2015 Jan 20;108(2):338-49. doi: 10.1016/j.bpj.2014.11.3472.

9.

Association equilibrium of the HIV-1 capsid protein in a crowded medium reveals that hexamerization during capsid assembly requires a functional C-domain dimerization interface.

Bocanegra R, Alfonso C, Rodríguez-Huete A, Fuertes MÁ, Jiménez M, Rivas G, Mateu MG.

Biophys J. 2013 Feb 19;104(4):884-93. doi: 10.1016/j.bpj.2012.12.035.

10.

Analysis of calcium-induced conformational changes in calcium-binding allergens and quantitative determination of their IgE binding properties.

Parody N, Fuertes MA, Alonso C, Pico de Coaña Y.

Methods Mol Biol. 2013;963:115-25. doi: 10.1007/978-1-62703-230-8_8.

PMID:
23296608
11.

Molecular recognition in the human immunodeficiency virus capsid and antiviral design.

Bocanegra R, Rodríguez-Huete A, Fuertes MÁ, Del Álamo M, Mateu MG.

Virus Res. 2012 Nov;169(2):388-410. doi: 10.1016/j.virusres.2012.06.016. Epub 2012 Jun 21. Review.

PMID:
22728445
12.

Introns form compositional clusters in parallel with the compositional clusters of the coding sequences to which they pertain.

Fuertes MA, Pérez JM, Zuckerkandl E, Alonso C.

J Mol Evol. 2011 Jan;72(1):1-13. doi: 10.1007/s00239-010-9411-6. Epub 2010 Dec 4.

PMID:
21132282
13.

Diagnostic and therapeutic challenges.

Ascaso FJ, Jimenez B, Fuertes MA, Sadda S, Keane PA.

Retina. 2011 May;31(5):994-7. doi: 10.1097/IAE.0b013e3181f98cbf. No abstract available.

PMID:
21102365
14.

Molecular cloning and characterization of Cup a 4, a new allergen from Cupressus arizonica.

Pico de Coaña Y, Parody N, Fuertes MÁ, Carnés J, Roncarolo D, Ariano R, Sastre J, Mistrello G, Alonso C.

Biochem Biophys Res Commun. 2010 Oct 22;401(3):451-7. doi: 10.1016/j.bbrc.2010.09.079. Epub 2010 Sep 24.

PMID:
20869950
15.

Cellular Uptake, DNA Binding and Apoptosis Induction of Cytotoxic Trans-[PtCl(2)(N,N-dimethylamine)(Isopropylamine)] in A2780cisR Ovarian Tumor Cells.

Pérez JM, Montero EI, Quiroga AG, Fuertes MA, Alonso C, Navarro-Ranninger C.

Met Based Drugs. 2001;8(1):29-37. doi: 10.1155/MBD.2001.29.

16.

Anticancer compounds as leishmanicidal drugs: challenges in chemotherapy and future perspectives.

Fuertes MA, Nguewa PA, Castilla J, Alonso C, Pérez JM.

Curr Med Chem. 2008;15(5):433-9. Review.

PMID:
18288998
17.

Poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors in cancer chemotherapy.

Cepeda V, Fuertes MA, Castilla J, Alonso C, Quevedo C, Soto M, Pérez JM.

Recent Pat Anticancer Drug Discov. 2006 Jan;1(1):39-53. Review.

PMID:
18221025
18.

Apoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes.

Montero EI, Pérez JM, Schwartz A, Fuertes MA, Malinge JM, Alonso C, Leng M, Navarro-Ranninger C.

Chembiochem. 2002 Jan 4;3(1):61-7.

PMID:
17590955
19.

Results of a pilot trial of immunotherapy with dendritic cells pulsed with autologous tumor lysates in patients with advanced cancer.

Mayordomo JI, Andres R, Isla MD, Murillo L, Cajal R, Yubero A, Blasco C, Lasierra P, Palomera L, Fuertes MA, Güemes A, Sousa R, Garcia-Prats MD, Escudero P, Saenz A, Godino J, Marco I, Saez B, Visus C, Asin L, Valdivia G, Larrad L, Tres A.

Tumori. 2007 Jan-Feb;93(1):26-30.

PMID:
17455868
20.

Structural and functional analysis of phi29 p16.7C dimerization mutants: identification of a novel aromatic cage dimerization motif.

Muñoz-Espín D, Fuertes MA, Jiménez M, Villar L, Alonso C, Rivas G, Salas M, Meijer WJ.

J Biol Chem. 2007 Jun 1;282(22):16521-31. Epub 2007 Apr 9.

21.

Biochemical mechanisms of cisplatin cytotoxicity.

Cepeda V, Fuertes MA, Castilla J, Alonso C, Quevedo C, Pérez JM.

Anticancer Agents Med Chem. 2007 Jan;7(1):3-18. Review.

PMID:
17266502
22.

Pentamidine is an antiparasitic and apoptotic drug that selectively modifies ubiquitin.

Nguewa PA, Fuertes MA, Cepeda V, Iborra S, Carrión J, Valladares B, Alonso C, Pérez JM.

Chem Biodivers. 2005 Oct;2(10):1387-400.

PMID:
17191940
23.

Poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide enhances apoptosis induction by platinum complexes in cisplatin-resistant tumor cells.

Nguewa PA, Fuertes MA, Cepeda V, Alonso C, Quevedo C, Soto M, Pérez JM.

Med Chem. 2006 Jan;2(1):47-53.

PMID:
16787355
24.

Molecular mechanisms for the B-Z transition in the example of poly[d(G-C) x d(G-C)] polymers. A critical review.

Fuertes MA, Cepeda V, Alonso C, Pérez JM.

Chem Rev. 2006 Jun;106(6):2045-64. Review. No abstract available.

PMID:
16771442
25.

Water soluble cationic trans-platinum complexes which induce programmed cell death in the protozoan parasite Leishmania infantum.

Nguewa PA, Fuertes MA, Iborra S, Najajreh Y, Gibson D, Martínez E, Alonso C, Pérez JM.

J Inorg Biochem. 2005 Mar;99(3):727-36. Epub 2005 Jan 1.

PMID:
15708793
26.

Phosphorylation modulates the alpha-helical structure and polymerization of a peptide from the third tau microtubule-binding repeat.

Mendieta J, Fuertes MA, Kunjishapatham R, Santa-María I, Moreno FJ, Alonso C, Gago F, Muñoz V, Avila J, Hernández F.

Biochim Biophys Acta. 2005 Jan 18;1721(1-3):16-26. Epub 2004 Nov 5.

PMID:
15652175
27.

Poly(ADP-ribose) polymerases: homology, structural domains and functions. Novel therapeutical applications.

Nguewa PA, Fuertes MA, Valladares B, Alonso C, Pérez JM.

Prog Biophys Mol Biol. 2005 May;88(1):143-72. Review.

PMID:
15561303
28.

Nuclear localization signal-targeted poly(ethylene glycol) conjugates as potential carriers and nuclear localizing agents for carboplatin analogues.

Aronov O, Horowitz AT, Gabizon A, Fuertes MA, Pérez JM, Gibson D.

Bioconjug Chem. 2004 Jul-Aug;15(4):814-23.

PMID:
15264869
29.

Programmed cell death in trypanosomatids: a way to maximize their biological fitness?

Nguewa PA, Fuertes MA, Valladares B, Alonso C, Pérez JM.

Trends Parasitol. 2004 Aug;20(8):375-80. Review.

PMID:
15246321
30.

Small amounts of urea and guanidine hydrochloride can be detected by a far-UV spectrophotometric method in dialysed protein solutions.

Fuertes MA, Pérez JM, Alonso C.

J Biochem Biophys Methods. 2004 Jun 30;59(3):209-16.

PMID:
15165752
31.

Thermodynamic stability of the C-terminal domain of the human inducible heat shock protein 70.

Fuertes MA, Pérez JM, Soto M, Menéndez M, Alonso C.

Biochim Biophys Acta. 2004 Jun 1;1699(1-2):45-56.

PMID:
15158711
32.

Pharmacological modulation of Poly(ADP-ribose) polymerase-mediated cell death: exploitation in cancer chemotherapy.

Nguewa PA, Fuertes MA, Alonso C, Perez JM.

Mol Pharmacol. 2003 Nov;64(5):1007-14. Review. No abstract available.

PMID:
14573748
33.

Synthesis, characterization, interaction with DNA and cytotoxicity of the new potential antitumour drug cis-K[Ru(eddp)Cl(2)].

Grguric-Sipka SR, Vilaplana RA, Pérez JM, Fuertes MA, Alonso C, Alvarez Y, Sabo TJ, González-Vílchez F.

J Inorg Biochem. 2003 Oct 1;97(2):215-20.

PMID:
14512200
34.

Novel concepts in the development of platinum antitumor drugs.

Fuertes MA, Castilla J, Alonso C, Pérez JM.

Curr Med Chem Anticancer Agents. 2002 Jul;2(4):539-51. Review.

PMID:
12678734
35.

Antitumor and cellular pharmacological properties of a novel platinum(IV) complex: trans-[PtCl(2)(OH)(2)(dimethylamine) (isopropylamine)].

Pérez JM, Kelland LR, Montero EI, Boxall FE, Fuertes MA, Alonso C, Navarro-Ranninger C.

Mol Pharmacol. 2003 Apr;63(4):933-44.

PMID:
12644595
36.

Biochemical modulation of Cisplatin mechanisms of action: enhancement of antitumor activity and circumvention of drug resistance.

Fuertes MA, Alonso C, Pérez JM.

Chem Rev. 2003 Mar;103(3):645-62. Review. No abstract available.

PMID:
12630848
37.
38.

A kinetic model for the B-Z transition of poly[d(G-C)].poly[d(G-C)] and poly[d(G-m5C)].poly[d(G-m5C)].

Fuertes MA, Pérez JM, González VM, Alonso C.

J Biol Inorg Chem. 2001 Sep;6(7):675-82.

PMID:
11681701
39.

Is cisplatin-induced cell death always produced by apoptosis?

Gonzalez VM, Fuertes MA, Alonso C, Perez JM.

Mol Pharmacol. 2001 Apr;59(4):657-63. Review.

PMID:
11259608
40.

Calcium-induced conformational changes in Leishmania infantum kinetoplastid membrane protein-11.

Fuertes MA, Pérez JM, Soto M, López MC, Alonso C.

J Biol Inorg Chem. 2001 Jan;6(1):107-17.

PMID:
11191218
41.

Current status of the development of trans-platinum antitumor drugs.

Pérez JM, Fuertes MA, Alonso C, Navarro-Ranninger C.

Crit Rev Oncol Hematol. 2000 Aug;35(2):109-20. Review.

PMID:
10936468
42.

X-Ray structure of cytotoxic trans-[PtCl(2)(dimethylamine)(isopropylamine)]: interstrand cross-link efficiency, DNA sequence specificity, and inhibition of the B-Z transition.

Pérez JM, Montero EI, González AM, Solans X, Font-Bardia M, Fuertes MA, Alonso C, Navarro-Ranninger C.

J Med Chem. 2000 Jun 15;43(12):2411-8.

PMID:
10882368
43.

[Relation between preoperative plasma levels of hypercoagulation markers and acute phase reactants in patients with rheumatoid arthritis who are candidates for hip or knee arthroplasty].

Iturbe T, de Miguel R, Cornudella R, Varo MJ, Fuertes MA, Seral F, Gutiérrez M.

Rev Clin Esp. 2000 Apr;200(4):234-5. Spanish. No abstract available.

PMID:
10857414
44.

Induction of apoptosis by the bis-Pt(III) complex [Pt(2)(2-mercaptopyrimidine)(4)Cl(2)].

González VM, Fuertes MA, Pérez-Alvarez MJ, Cervantes G, Moreno V, Alonso C, Pérez JM.

Biochem Pharmacol. 2000 Aug 1;60(3):371-9.

PMID:
10856432
45.

[Autoimmune thrombocytopenia in the clinical context of myelodysplasia with chromosome 7 deletion, intestinal tuberculosis, and chronic hepatitis caused by hepatitis C virus].

Olave MT, Iturbe T, Fuertes MA, Palomera L.

Sangre (Barc). 1999 Dec;44(6):495-6. Spanish. No abstract available.

PMID:
10822772
46.

Empirical validation of a two-state kinetic model for the B-Z transition of double-stranded poly[d(G-m5C)].

Fuertes MA, Pérez JM, González VM, Alonso C.

J Biol Inorg Chem. 1999 Dec;4(6):759-65.

47.

[Activated protein C resistance of an acquired nature: the potential role of hormonal treatment and of elevated factor VIII plasma levels].

Iturbe Hernández T, Varo MJ, Olave MT, Fuertes MA, Cornudella R.

Rev Clin Esp. 1999 Sep;199(9):618. Spanish. No abstract available.

PMID:
10568160
48.

The formation of DNA interstrand cross-links by a novel bis-[Pt2Cl4(diminazene aceturate)2]Cl4.4H2O complex inhibits the B to Z transition.

González VM, Fuertes MA, Jiménez-Ruíz A, Alonso C, Pérez JM.

Mol Pharmacol. 1999 Apr;55(4):770-7.

PMID:
10101036
49.

Folding stability of the kinetoplastid membrane protein-11 (KMP-11) from Leishmania infantum.

Fuertes MA, Berberich C, Lozano RM, Gimenez-Gallego G, Alonso C.

Eur J Biochem. 1999 Mar;260(2):559-67.

50.

[Hypercoagulability status previous to total hip and knee arthroplasty: the contribution of rheumatoid arthritis].

Iturbe T, Cornudella R, de Miguel R, Olave MT, Azaceta G, Varo MJ, Moreno JA, Fuertes MA, Gutiérrez M.

Sangre (Barc). 1998 Oct;43(5):376-9. Spanish.

PMID:
9868328

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