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[Research progress on anti-tumor effects and mechanisms of triptolide and its combined application].

Shi JF, Luo YY, Li JX, Luo RF, Chen L, Li J, Zhang JM, Fu CM.

Zhongguo Zhong Yao Za Zhi. 2019 Aug;44(16):3391-3398. doi: 10.19540/j.cnki.cjcmm.20190610.402. Chinese.


A feasible biocompatible hydrogel film embedding Periplaneta americana extract for acute wound healing.

Chen Z, Hu Y, Li J, Zhang C, Gao F, Ma X, Zhang J, Fu C, Geng F.

Int J Pharm. 2019 Oct 5:118707. doi: 10.1016/j.ijpharm.2019.118707. [Epub ahead of print]


New different origins and evolutionary processes of AP2/EREBP transcription factors in Taxus chinensis.

Zhang M, Chen Y, Jin X, Cai Y, Yuan Y, Fu C, Yu L.

BMC Plant Biol. 2019 Oct 7;19(1):413. doi: 10.1186/s12870-019-2044-z.


Hybridizing Ag-Doped ZnO nanoparticles with graphite as potential photocatalysts for enhanced removal of metronidazole antibiotic from water.

Tran ML, Nguyen CH, Fu CC, Juang RS.

J Environ Manage. 2019 Oct 3;252:109611. doi: 10.1016/j.jenvman.2019.109611. [Epub ahead of print]


Effect of dissolved organic matters on adsorption and desorption behavior of heavy metals in a water-level-fluctuation zone of the Three Gorges Reservoir, China.

Huang Y, Fu C, Li Z, Fang F, Ouyang W, Guo J.

Ecotoxicol Environ Saf. 2019 Sep 29;185:109695. doi: 10.1016/j.ecoenv.2019.109695. [Epub ahead of print]


Performance of simple fibrosis scores in non-obese patients with nonalcoholic fatty liver disease.

Fu C, Wai JW, Nik Mustapha NR, Irles M, Lai-Hung Wong G, Mahadeva S, Shili S, Wing-Hung Chan A, Merrouche W, Lik-Yuen Chan H, Foucher J, Le Bail B, Wai-Sun Wong V, Chan WK, de Lédinghen V.

Clin Gastroenterol Hepatol. 2019 Sep 28. pii: S1542-3565(19)31076-6. doi: 10.1016/j.cgh.2019.09.027. [Epub ahead of print] No abstract available.


Amplitude Analysis of D_{s}^{+}→π^{+}π^{0}η and First Observation of the W-Annihilation Dominant Decays D_{s}^{+}→a_{0}(980)^{+}π^{0} and D_{s}^{+}→a_{0}(980)^{0}π^{+}.

Ablikim M, Achasov MN, Ahmed S, Albrecht M, Alekseev M, Amoroso A, An FF, An Q, Bai JZ, Bai Y, Bakina O, Baldini Ferroli R, Ban Y, Begzsuren K, Bennett JV, Berger N, Bertani M, Bettoni D, Bianchi F, Boger E, Boyko I, Briere RA, Cai H, Cai X, Calcaterra A, Cao GF, Cao N, Cetin SA, Chai J, Chang JF, Chelkov G, Chen G, Chen HS, Chen JC, Chen ML, Chen SJ, Chen XR, Chen YB, Cheng W, Chu XK, Cibinetto G, Cossio F, Cui XF, Dai HL, Dai JP, Dbeyssi A, Dedovich D, Deng ZY, Denig A, Denysenko I, Destefanis M, De Mori F, Ding Y, Dong C, Dong J, Dong LY, Dong MY, Du SX, Fang J, Fang SS, Fang Y, Farinelli R, Fava L, Feldbauer F, Felici G, Feng CQ, Fritsch M, Fu CD, Gao Q, Gao XL, Gao Y, Gao Y, Gao YG, Gao Z, Garillon B, Garzia I, Gilman A, Goetzen K, Gong L, Gong WX, Gradl W, Greco M, Gu MH, Gu YT, Guo AQ, Guo RP, Guo YP, Guskov A, Han S, Hao XQ, Harris FA, He KL, He XQ, Heinsius FH, Held T, Heng YK, Hou YR, Hou ZL, Hu HM, Hu JF, Hu T, Hu Y, Huang GS, Huang JS, Huang XT, Huang ZL, Hussain T, Ikegami Andersson W, Imoehl W, Irshad M, Ji Q, Ji QP, Ji XB, Ji XL, Jiang XS, Jiang XY, Jiao JB, Jiao Z, Jin DP, Jin S, Jin Y, Johansson T, Kalantar-Nayestanaki N, Kang XS, Kappert R, Kavatsyuk M, Ke BC, Keshk IK, Khan T, Khoukaz A, Kiese P, Kiuchi R, Kliemt R, Koch L, Kolcu OB, Kopf B, Kuemmel M, Kuessner M, Kupsc A, Kurth M, Kurth MG, Kühn W, Lange JS, Larin P, Lavezzi L, Leithoff H, Li C, Li C, Li DM, Li F, Li FY, Li G, Li HB, Li HJ, Li JC, Li JW, Li J, Li KJ, Li K, Li K, Li LK, Li L, Li PL, Li PR, Li QY, Li WD, Li WG, Li XL, Li XN, Li XQ, Li ZB, Liang H, Liang H, Liang YF, Liang YT, Liao GR, Liao LZ, Libby J, Lin CX, Lin DX, Liu B, Liu BJ, Liu CX, Liu D, Liu DY, Liu FH, Liu F, Liu F, Liu HB, Liu HM, Liu H, Liu H, Liu JB, Liu JY, Liu KY, Liu K, Liu LD, Liu Q, Liu SB, Liu X, Liu XY, Liu YB, Liu ZA, Liu Z, Long YF, Lou XC, Lu HJ, Lu JG, Lu Y, Lu YP, Luo CL, Luo MX, Luo T, Luo XL, Lusso S, Lyu XR, Ma FC, Ma HL, Ma LL, Ma MM, Ma QM, Ma T, Ma XN, Ma XY, Ma YM, Maas FE, Maggiora M, Maldaner S, Malik QA, Mangoni A, Mao YJ, Mao ZP, Marcello S, Meng ZX, Messchendorp JG, Mezzadri G, Min J, Mitchell RE, Mo XH, Mo YJ, Morales Morales C, Muchnoi NY, Muramatsu H, Mustafa A, Nefedov Y, Nerling F, Nikolaev IB, Ning Z, Nisar S, Niu SL, Niu XY, Olsen SL, Ouyang Q, Pacetti S, Pan Y, Papenbrock M, Patteri P, Pelizaeus M, Pellegrino J, Peng HP, Peters K, Pettersson J, Ping JL, Ping RG, Pitka A, Poling R, Prasad V, Qi M, Qi TY, Qian S, Qiao CF, Qin N, Qin XS, Qin ZH, Qiu JF, Qu SQ, Rashid KH, Redmer CF, Richter M, Ripka M, Rivetti A, Rodin V, Rolo M, Rong G, Rosner C, Sarantsev A, Savrié M, Schoenning K, Shan W, Shan XY, Shao M, Shen CP, Shen PX, Shen XY, Sheng HY, Shi X, Song JJ, Song XY, Sosio S, Sowa C, Spataro S, Sun GX, Sun JF, Sun L, Sun SS, Sun XH, Sun YJ, Sun YK, Sun YZ, Sun ZJ, Sun ZT, Tan YT, Tang CJ, Tang GY, Tang X, Tsednee B, Uman I, Wang B, Wang D, Wang DY, Wang K, Wang LL, Wang LS, Wang M, Wang M, Wang P, Wang PL, Wang WP, Wang XL, Wang Y, Wang YF, Wang Z, Wang ZG, Wang ZY, Wang Z, Weber T, Wei DH, Weidenkaff P, Wen SP, Wiedner U, Wolke M, Wu LH, Wu LJ, Wu Z, Xia L, Xia Y, Xiao SY, Xiao YJ, Xiao ZJ, Xie YG, Xie YH, Xiong XA, Xiu QL, Xu GF, Xu JJ, Xu L, Xu QJ, Xu XP, Yan F, Yan L, Yan WB, Yan WC, Yan YH, Yang HJ, Yang HX, Yang L, Yang RX, Yang YH, Yang YX, Yang Y, Yang ZQ, Ye M, Ye MH, Yin JH, You ZY, Yu BX, Yu CX, Yu JS, Yu JS, Yuan CZ, Yuan Y, Yuncu A, Zafar AA, Zeng Y, Zhang BX, Zhang BY, Zhang CC, Zhang DH, Zhang HH, Zhang HY, Zhang J, Zhang JL, Zhang JQ, Zhang JW, Zhang JY, Zhang JZ, Zhang K, Zhang L, Zhang TJ, Zhang XY, Zhang Y, Zhang YH, Zhang YT, Zhang Y, Zhang Y, Zhang Y, Zhang ZH, Zhang ZP, Zhang ZY, Zhao G, Zhao JW, Zhao JY, Zhao JZ, Zhao L, Zhao L, Zhao MG, Zhao Q, Zhao SJ, Zhao TC, Zhao YB, Zhao ZG, Zhemchugov A, Zheng B, Zheng JP, Zheng YH, Zhong B, Zhou L, Zhou Q, Zhou X, Zhou XK, Zhou XR, Zhou X, Zhou X, Zhu AN, Zhu J, Zhu J, Zhu K, Zhu KJ, Zhu SH, Zhu WJ, Zhu XL, Zhu YC, Zhu YS, Zhu ZA, Zhuang J, Zou BS, Zou JH; BESIII Collaboration.

Phys Rev Lett. 2019 Sep 13;123(11):112001. doi: 10.1103/PhysRevLett.123.112001.


Synthesis of Bis-β-Diketonate Lanthanide Complexes with an Azobenzene Bridge and Studies of Their Reversible Photo/Thermal Isomerization Properties.

Fu CY, Chen L, Wang X, Lin LR.

ACS Omega. 2019 Sep 9;4(13):15530-15538. doi: 10.1021/acsomega.9b01817. eCollection 2019 Sep 24.


Papillary thyroid carcinoma with tracheal invasion: A case report.

Zhang J, Fu C, Cui K, Ma X.

Medicine (Baltimore). 2019 Sep;98(38):e17033. doi: 10.1097/MD.0000000000017033.


Detection of target collagen peptides with single amino acid mutation using two fluorescent peptide probes.

Sun X, Yao L, Fu C, Luo L, Wang J, Xiao J.

J Mater Chem B. 2019 Sep 30. doi: 10.1039/c9tb00610a. [Epub ahead of print]


Poly (lactic-co-glycolic acid)/graphene oxide composites combined with electrical stimulation in wound healing: preparation and characterization.

You D, Li K, Guo W, Zhao G, Fu C.

Int J Nanomedicine. 2019 Aug 30;14:7039-7052. doi: 10.2147/IJN.S216365. eCollection 2019.


Glucose starvation induces mitochondrial fragmentation depending on the dynamin GTPase Dnm1/Drp1 in fission yeast.

Zheng F, Jia B, Dong F, Liu L, Rasul F, He J, Fu C.

J Biol Chem. 2019 Sep 27. pii: jbc.RA119.010185. doi: 10.1074/jbc.RA119.010185. [Epub ahead of print]


Study on High-Temperature Interaction Mechanism of Nd-Fe-As System.

Fu C, Huang R, Xie W, Luo J, Li Y, Zhang J.

Materials (Basel). 2019 Sep 20;12(19). pii: E3060. doi: 10.3390/ma12193060.


Discovery of a Ruthenium Complex for the Theranosis of Glioma through Targeting the Mitochondrial DNA with Bioinformatic Methods.

Zhang L, Fu C, Li J, Zhao Z, Hou Y, Zhou W, Fu A.

Int J Mol Sci. 2019 Sep 19;20(18). pii: E4643. doi: 10.3390/ijms20184643.


In Situ Modification of a Delafossite-Type PdCoO2 Bulk Single Crystal for Reversible Hydrogen Sorption and Fast Hydrogen Evolution.

Li G, Khim S, Chang CS, Fu C, Nandi N, Li F, Yang Q, Blake GR, Parkin S, Auffermann G, Sun Y, Muller DA, Mackenzie AP, Felser C.

ACS Energy Lett. 2019 Sep 13;4(9):2185-2191. doi: 10.1021/acsenergylett.9b01527. Epub 2019 Aug 15.


Insight into the Rapid Degradation Behavior of Nonprecious Metal Fe-N-C Electrocatalyst-Based Proton Exchange Membrane Fuel Cells.

Chen J, Yan X, Fu C, Feng Y, Lin C, Li X, Shen S, Ke C, Zhang J.

ACS Appl Mater Interfaces. 2019 Oct 2. doi: 10.1021/acsami.9b13474. [Epub ahead of print]


FENDRR reduces tumor invasiveness in prostate cancer PC-3 cells by targeting CSNK1E.

Zhang YQ, Chen X, Fu CL, Zhang W, Zhang DL, Pang C, Liu M, Wang JY.

Eur Rev Med Pharmacol Sci. 2019 Sep;23(17):7327-7337. doi: 10.26355/eurrev_201909_18838.


Numerical and Experimental Investigation of Impacts of Nonlinear Scattering Encapsulated Microbubbles on Nakagami Distribution.

Wang D, Sang Y, Zhang X, Hu H, Lu S, Zhang Y, Fu C, Cloutier G, Wan M.

Med Phys. 2019 Sep 19. doi: 10.1002/mp.13833. [Epub ahead of print]


Unisexual reproduction promotes competition for mating partners in the global human fungal pathogen Cryptococcus deneoformans.

Fu C, Thielhelm TP, Heitman J.

PLoS Genet. 2019 Sep 19;15(9):e1008394. doi: 10.1371/journal.pgen.1008394. eCollection 2019 Sep.


Maintenance therapy with decitabine after allogeneic hematopoietic stem cell transplantation to prevent relapse of high-risk acute myeloid leukemia.

Ma Y, Qu C, Dai H, Yin J, Li Z, Chen J, Qiu H, Sun A, Miao M, Fu C, Jin Z, Zhu X, Wu D, Tang X.

Bone Marrow Transplant. 2019 Sep 18. doi: 10.1038/s41409-019-0677-z. [Epub ahead of print] No abstract available.


Clinical efficacy of tirofiban combined with a Solitaire stent in treating acute ischemic stroke.

Zhang Y, Zhang QQ, Fu C, Wang L, Zhang GQ, Cao PW, Chen GF, Fu XM.

Braz J Med Biol Res. 2019;52(10):e8396. doi: 10.1590/1414-431X20198396. Epub 2019 Sep 16.


Lethal Effect of Total Dissolved Gas-Supersaturated Water with Suspended Sediment on River Sturgeon (Acipenser dabryanus).

Liu X, Li N, Feng C, Fu C, Gong Q, Lai J, Jiang Z, Yang Y, Shi H.

Sci Rep. 2019 Sep 16;9(1):13373. doi: 10.1038/s41598-019-49800-y.


Addressing heterogeneity (and homogeneity) in treatment mechanisms in depression and the potential to develop diagnostic and predictive biomarkers.

Fu CHY, Fan Y, Davatzikos C.

Neuroimage Clin. 2019 Aug 28;24:101997. doi: 10.1016/j.nicl.2019.101997. [Epub ahead of print]


Degradation of bisphenol A by persulfate coupled with dithionite: Optimization using response surface methodology and pathway.

Song W, Li J, Wang Z, Fu C, Zhang X, Feng J, Xu Z, Song Q.

Sci Total Environ. 2019 Sep 2;699:134258. doi: 10.1016/j.scitotenv.2019.134258. [Epub ahead of print]


Resequencing 545 ginkgo genomes across the world reveals the evolutionary history of the living fossil.

Zhao YP, Fan G, Yin PP, Sun S, Li N, Hong X, Hu G, Zhang H, Zhang FM, Han JD, Hao YJ, Xu Q, Yang X, Xia W, Chen W, Lin HY, Zhang R, Chen J, Zheng XM, Lee SM, Lee J, Uehara K, Wang J, Yang H, Fu CX, Liu X, Xu X, Ge S.

Nat Commun. 2019 Sep 13;10(1):4201. doi: 10.1038/s41467-019-12133-5.


Copper-catalyzed radical approach to allenyl iodides.

Song Y, Song S, Duan X, Wu X, Jiang F, Zhang Y, Fan J, Huang X, Fu C, Ma S.

Chem Commun (Camb). 2019 Sep 26;55(78):11774-11777. doi: 10.1039/c9cc05853b.


Dimethyl fumarate attenuates lipopolysaccharide-induced mitochondrial injury by activating Nrf2 pathway in cardiomyocytes.

Fu CY, Chen J, Lu XY, Zheng MZ, Wang LL, Shen YL, Chen YY.

Life Sci. 2019 Sep 9;235:116863. doi: 10.1016/j.lfs.2019.116863. [Epub ahead of print]


Ratiometric Fluorescent Strategy for Localizing Alkaline Phosphatase Activity in Mitochondria Based on the ESIPT Process.

Zhang P, Fu C, Zhang Q, Li S, Ding C.

Anal Chem. 2019 Oct 1;91(19):12377-12383. doi: 10.1021/acs.analchem.9b02917. Epub 2019 Sep 12.


Endowing g-C3 N4 Membranes with Superior Permeability and Stability by Using Acid Spacers.

Ran J, Pan T, Wu Y, Chu C, Cui P, Zhang P, Ai X, Fu CF, Yang Z, Xu T.

Angew Chem Int Ed Engl. 2019 Sep 11. doi: 10.1002/anie.201908786. [Epub ahead of print]


Clinical development of CT-P6 in HER2 positive breast cancer.

Fu C, Stebbing J, Esteva FJ.

Expert Opin Biol Ther. 2019 Oct;19(10):987-992. doi: 10.1080/14712598.2019.1665019. Epub 2019 Sep 11.


MeLAD: an integrated resource for metalloenzyme-ligand associations.

Li G, Su Y, Yan YH, Peng JY, Dai QQ, Ning XL, Zhu CL, Fu C, McDonough MA, Schofield CJ, Huang C, Li GB.

Bioinformatics. 2019 Aug 26. pii: btz648. doi: 10.1093/bioinformatics/btz648. [Epub ahead of print]


What drives depression in empty nose syndrome? A Sinonasal Outcome Test-25 subdomain analysis.

Huang CC, Wu PW, Fu CH, Huang CC, Chang PH, Wu CL, Lee TJ.

Rhinology. 2019 Sep 10. doi: 10.4193/Rhin19.085. [Epub ahead of print]


Endothelial CDS2 deficiency causes VEGFA-mediated vascular regression and tumor inhibition.

Zhao W, Cao L, Ying H, Zhang W, Li D, Zhu X, Xue W, Wu S, Cao M, Fu C, Qi H, Hao Y, Tang YC, Qin J, Zhong TP, Lin X, Yu L, Li X, Li L, Wu D, Pan W.

Cell Res. 2019 Sep 9. doi: 10.1038/s41422-019-0229-5. [Epub ahead of print]


The protective effects of grape seed procyanidin B2 against asporin mediates glycated low-density lipoprotein induced-cardiomyocyte apoptosis and fibrosis.

Li XL, Yu F, Li BY, Fu CL, Yu X, Xu M, Cheng M, Gao HQ.

Cell Biol Int. 2019 Sep 9. doi: 10.1002/cbin.11229. [Epub ahead of print]


(Pro)renin Receptor is Involved in Myocardial Damage in Alcoholic Cardiomyopathy.

Xiong J, Cao X, Qiao S, Yu S, Li L, Yu Y, Fu C, Jiang F, Dong B, Su Q.

Alcohol Clin Exp Res. 2019 Sep 9. doi: 10.1111/acer.14188. [Epub ahead of print]


[Allogeneic CAR-T for treatment of relapsed and/or refractory multiple myeloma: four cases report and literatures review].

Yan LZ, Shang JJ, Shi XL, Qu S, Kang LQ, Xu N, Chang WR, Yu L, Wu DP, Fu CC.

Zhonghua Xue Ye Xue Za Zhi. 2019 Aug 14;40(8):650-655. doi: 10.3760/cma.j.issn.0253-2727.2019.08.005. Review. Chinese.


Epidemiological features and trends of influenza incidence in mainland China: a population-based surveillance study from 2005 to 2015.

Sun S, Fu C, Cong J, Li Y, Xie S, Wang P.

Int J Infect Dis. 2019 Sep 3. pii: S1201-9712(19)30354-6. doi: 10.1016/j.ijid.2019.08.028. [Epub ahead of print]


Comment on "Photodynamic therapy in the treatment of basal cell carcinoma: A systematic review and meta-analysis".

Fu C, Qin L, Zeng XY, Wang BC.

Photodiagnosis Photodyn Ther. 2019 Sep 3. pii: S1572-1000(19)30390-4. doi: 10.1016/j.pdpdt.2019.08.033. [Epub ahead of print] No abstract available.


Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species.

Ng AYH, Li Z, Jones MM, Yang S, Li C, Fu C, Tu C, Oursler MJ, Qu J, Yang S.

Elife. 2019 Sep 6;8. pii: e42951. doi: 10.7554/eLife.42951.


Bioinformatics Analysis Suggests the Combined Expression of AURKB and KIF18B Being an Important Event in the Development of Clear Cell Renal Cell Carcinoma.

Liu Q, Zhang X, Tang H, Liu J, Fu C, Sun M, Zhao L, Wei M, Yu Z, Wang P.

Pathol Oncol Res. 2019 Sep 5. doi: 10.1007/s12253-019-00740-y. [Epub ahead of print]


Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload.

Ge C, Huang H, Huang F, Yang T, Zhang T, Wu H, Zhou H, Chen Q, Shi Y, Sun Y, Liu L, Wang X, Pearson RB, Cao Y, Kang J, Fu C.

Proc Natl Acad Sci U S A. 2019 Sep 24;116(39):19635-19645. doi: 10.1073/pnas.1908998116. Epub 2019 Sep 5.


Dose effect of influenza vaccine on protection against laboratory-confirmed influenza illness among children aged 6 months to 8 years of age in southern China, 2013/14-2015/16 seasons: a matched case-control study.

Fu C, Greene CM, He Q, Liao Y, Wan Y, Shen J, Rong C, Zhou S.

Hum Vaccin Immunother. 2019 Sep 30:1-7. doi: 10.1080/21645515.2019.1662267. [Epub ahead of print]


Decreased Expression of Urinary Mammalian Target of Rapamycin mRNA Is Related to Chronic Renal Fibrosis in IgAN.

Cao Y, Wang Y, Liu Y, Zhu X, Zhang G, Wang S, Chen X, Liu D, Fu C.

Dis Markers. 2019 Aug 14;2019:2424751. doi: 10.1155/2019/2424751. eCollection 2019.


Genetic and genomic evolution of sexual reproduction: echoes from LECA to the fungal kingdom.

Fu C, Coelho MA, David-Palma M, Priest SJ, Heitman J.

Curr Opin Genet Dev. 2019 Aug 29;58-59:70-75. doi: 10.1016/j.gde.2019.07.008. [Epub ahead of print] Review.


The Effects of Logotherapy on Distress, Depression, and Demoralization in Breast Cancer and Gynecological Cancer Patients: A Preliminary Study.

Sun FK, Hung CM, Yao Y, Fu CF, Tsai PJ, Chiang CY.

Cancer Nurs. 2019 Aug 28. doi: 10.1097/NCC.0000000000000740. [Epub ahead of print]


A Simple Genome Walking Strategy to Isolate Unknown Genomic Regions Using Long Primer and RAPD Primer.

Li F, Fu C, Li Q.

Iran J Biotechnol. 2019 Apr 20;17(2):e2183. doi: 10.21859/ijb.2183. eCollection 2019 Apr.


Locating Ultrasonic Signals Employing MEMS-On-Fiber Sensors.

Si W, Fu C, Li H, Lv J, Xiong C, Yuan P, Yu Y.

Sensors (Basel). 2019 Aug 26;19(17). pii: E3696. doi: 10.3390/s19173696.


Ratiometric SERS biosensor for sensitive and reproducible detection of microRNA based on mismatched catalytic hairpin assembly.

Chen J, Wu Y, Fu C, Cao H, Tan X, Shi W, Wu Z.

Biosens Bioelectron. 2019 Oct 15;143:111619. doi: 10.1016/j.bios.2019.111619. Epub 2019 Aug 22.


FSP1 promotes the biofunctions of adventitial fibroblast through the crosstalk among RAGE, JAK2/STAT3 and Wnt3a/β-catenin signalling pathways.

Fu C, Liu P, Li P, Liu W, Huang X, Liang Y.

J Cell Mol Med. 2019 Aug 27. doi: 10.1111/jcmm.14518. [Epub ahead of print]

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