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Items: 1 to 50 of 122

1.

Differential effects of Down's syndrome and Alzheimer's neuropathology on default mode connectivity.

Wilson LR, Vatansever D, Annus T, Williams GB, Hong YT, Fryer TD, Nestor PJ, Holland AJ, Zaman SH.

Hum Brain Mapp. 2019 Oct 15;40(15):4551-4563. doi: 10.1002/hbm.24720. Epub 2019 Jul 26.

PMID:
31350817
2.

Delineating the topography of amyloid-associated cortical atrophy in Down syndrome.

Mak E, Padilla C, Annus T, Wilson LR, Hong YT, Fryer TD, Coles JP, Aigbirhio FI, Menon DK, Nestor PJ, Zaman SH, Holland AJ.

Neurobiol Aging. 2019 Aug;80:196-202. doi: 10.1016/j.neurobiolaging.2019.02.018. Epub 2019 Mar 5.

PMID:
31207551
3.

Fractionating Blunted Reward Processing Characteristic of Anhedonia by Over-Activating Primate Subgenual Anterior Cingulate Cortex.

Alexander L, Gaskin PLR, Sawiak SJ, Fryer TD, Hong YT, Cockcroft GJ, Clarke HF, Roberts AC.

Neuron. 2019 Jan 16;101(2):307-320.e6. doi: 10.1016/j.neuron.2018.11.021. Epub 2018 Dec 4.

4.

In vivo coupling of tau pathology and cortical thinning in Alzheimer's disease.

Mak E, Bethlehem RAI, Romero-Garcia R, Cervenka S, Rittman T, Gabel S, Surendranathan A, Bevan-Jones RW, Passamonti L, Vázquez Rodríguez P, Su L, Arnold R, Williams GB, Hong YT, Fryer TD, Aigbirhio FI, Rowe JB, O'Brien JT.

Alzheimers Dement (Amst). 2018 Sep 17;10:678-687. doi: 10.1016/j.dadm.2018.08.005. eCollection 2018.

5.

Early microglial activation and peripheral inflammation in dementia with Lewy bodies.

Surendranathan A, Su L, Mak E, Passamonti L, Hong YT, Arnold R, Vázquez Rodríguez P, Bevan-Jones WR, Brain SAE, Fryer TD, Aigbirhio FI, Rowe JB, O'Brien JT.

Brain. 2018 Dec 1;141(12):3415-3427. doi: 10.1093/brain/awy265.

6.

Relationships between selective neuronal loss and microglial activation after ischaemic stroke in man.

Morris RS, Simon Jones P, Alawneh JA, Hong YT, Fryer TD, Aigbirhio FI, Warburton EA, Baron JC.

Brain. 2018 Jul 1;141(7):2098-2111. doi: 10.1093/brain/awy121.

PMID:
29746644
7.

[11C]PK11195 binding in Alzheimer disease and progressive supranuclear palsy.

Passamonti L, Rodríguez PV, Hong YT, Allinson KSJ, Bevan-Jones WR, Williamson D, Jones PS, Arnold R, Borchert RJ, Surendranathan A, Mak E, Su L, Fryer TD, Aigbirhio FI, O'Brien JT, Rowe JB.

Neurology. 2018 May 29;90(22):e1989-e1996. doi: 10.1212/WNL.0000000000005610. Epub 2018 Apr 27.

8.

Effects of hyperoxia on 18F-fluoro-misonidazole brain uptake and tissue oxygen tension following middle cerebral artery occlusion in rodents: Pilot studies.

Fryer TD, Ejaz S, Jensen-Kondering U, Williamson DJ, Sitnikov S, Sawiak SJ, Aigbirhio FI, Hong YT, Baron JC.

PLoS One. 2017 Nov 1;12(11):e0187087. doi: 10.1371/journal.pone.0187087. eCollection 2017.

9.

[18F]AV-1451 binding in vivo mirrors the expected distribution of TDP-43 pathology in the semantic variant of primary progressive aphasia.

Bevan-Jones WR, Cope TE, Jones PS, Passamonti L, Hong YT, Fryer TD, Arnold R, Allinson KSJ, Coles JP, Aigbirhio FI, Patterson K, O'Brien JT, Rowe JB.

J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1032-1037. doi: 10.1136/jnnp-2017-316402. Epub 2017 Sep 14.

10.

Converging Prefronto-Insula-Amygdala Pathways in Negative Emotion Regulation in Marmoset Monkeys.

Shiba Y, Oikonomidis L, Sawiak S, Fryer TD, Hong YT, Cockcroft G, Santangelo AM, Roberts AC.

Biol Psychiatry. 2017 Dec 15;82(12):895-903. doi: 10.1016/j.biopsych.2017.06.016. Epub 2017 Jun 23.

11.

Brain hypoxia mapping in acute stroke: Back-to-back T2' MR versus 18F-fluoromisonidazole PET in rodents.

Jensen-Kondering U, Manavaki R, Ejaz S, Sawiak SJ, Carpenter TA, Fryer TD, Aigbirhio FI, Williamson DJ, Baron JC.

Int J Stroke. 2017 Oct;12(7):752-760. doi: 10.1177/1747493017706221. Epub 2017 May 19.

PMID:
28523963
12.

Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline.

Cole JH, Annus T, Wilson LR, Remtulla R, Hong YT, Fryer TD, Acosta-Cabronero J, Cardenas-Blanco A, Smith R, Menon DK, Zaman SH, Nestor PJ, Holland AJ.

Neurobiol Aging. 2017 Aug;56:41-49. doi: 10.1016/j.neurobiolaging.2017.04.006. Epub 2017 Apr 18.

13.

Vascular Imaging With 18F-Fluorodeoxyglucose Positron Emission Tomography Is Influenced by Hypoxia.

Joshi FR, Manavaki R, Fryer TD, Figg NL, Sluimer JC, Aigbirhio FI, Davenport AP, Kirkpatrick PJ, Warburton EA, Rudd JH.

J Am Coll Cardiol. 2017 Apr 11;69(14):1873-1874. doi: 10.1016/j.jacc.2017.01.050. No abstract available.

14.

Detection of Atherosclerotic Inflammation by 68Ga-DOTATATE PET Compared to [18F]FDG PET Imaging.

Tarkin JM, Joshi FR, Evans NR, Chowdhury MM, Figg NL, Shah AV, Starks LT, Martin-Garrido A, Manavaki R, Yu E, Kuc RE, Grassi L, Kreuzhuber R, Kostadima MA, Frontini M, Kirkpatrick PJ, Coughlin PA, Gopalan D, Fryer TD, Buscombe JR, Groves AM, Ouwehand WH, Bennett MR, Warburton EA, Davenport AP, Rudd JH.

J Am Coll Cardiol. 2017 Apr 11;69(14):1774-1791. doi: 10.1016/j.jacc.2017.01.060.

15.

The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis.

Annus T, Wilson LR, Acosta-Cabronero J, Cardenas-Blanco A, Hong YT, Fryer TD, Coles JP, Menon DK, Zaman SH, Holland AJ, Nestor PJ.

Neurobiol Aging. 2017 May;53:11-19. doi: 10.1016/j.neurobiolaging.2017.01.009. Epub 2017 Jan 17.

16.

18F-AV-1451 positron emission tomography in Alzheimer's disease and progressive supranuclear palsy.

Passamonti L, Vázquez Rodríguez P, Hong YT, Allinson KS, Williamson D, Borchert RJ, Sami S, Cope TE, Bevan-Jones WR, Jones PS, Arnold R, Surendranathan A, Mak E, Su L, Fryer TD, Aigbirhio FI, O'Brien JT, Rowe JB.

Brain. 2017 Mar 1;140(3):781-791. doi: 10.1093/brain/aww340.

17.

[18F]AV-1451 PET in behavioral variant frontotemporal dementia due to MAPT mutation.

Bevan Jones WR, Cope TE, Passamonti L, Fryer TD, Hong YT, Aigbirhio F, Kril JJ, Forrest SL, Allinson K, Coles JP, Simon Jones P, Spillantini MG, Hodges JR, O'Brien JT, Rowe JB.

Ann Clin Transl Neurol. 2016 Oct 18;3(12):940-947. doi: 10.1002/acn3.366. eCollection 2016 Dec.

18.

Neuroimaging of Inflammation in Memory and Related Other Disorders (NIMROD) study protocol: a deep phenotyping cohort study of the role of brain inflammation in dementia, depression and other neurological illnesses.

Bevan-Jones WR, Surendranathan A, Passamonti L, Vázquez Rodríguez P, Arnold R, Mak E, Su L, Coles JP, Fryer TD, Hong YT, Williams G, Aigbirhio F, Rowe JB, O'Brien JT.

BMJ Open. 2017 Jan 7;7(1):e013187. doi: 10.1136/bmjopen-2016-013187.

19.

High Structural Stress and Presence of Intraluminal Thrombus Predict Abdominal Aortic Aneurysm 18F-FDG Uptake: Insights From Biomechanics.

Huang Y, Teng Z, Elkhawad M, Tarkin JM, Joshi N, Boyle JR, Buscombe JR, Fryer TD, Zhang Y, Park AY, Wilkinson IB, Newby DE, Gillard JH, Rudd JH.

Circ Cardiovasc Imaging. 2016 Nov;9(11). pii: e004656.

20.

Neuroinflammatory and morphological changes in late-life depression: the NIMROD study.

Su L, Faluyi YO, Hong YT, Fryer TD, Mak E, Gabel S, Hayes L, Soteriades S, Williams GB, Arnold R, Passamonti L, Rodríguez PV, Surendranathan A, Bevan-Jones RW, Coles J, Aigbirhio F, Rowe JB, O'Brien JT.

Br J Psychiatry. 2016 Dec;209(6):525-526. Epub 2016 Oct 6.

21.

Hypoxia and tissue destruction in pulmonary TB.

Belton M, Brilha S, Manavaki R, Mauri F, Nijran K, Hong YT, Patel NH, Dembek M, Tezera L, Green J, Moores R, Aigbirhio F, Al-Nahhas A, Fryer TD, Elkington PT, Friedland JS.

Thorax. 2016 Dec;71(12):1145-1153. doi: 10.1136/thoraxjnl-2015-207402. Epub 2016 May 31.

22.

Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury.

Veenith TV, Carter EL, Geeraerts T, Grossac J, Newcombe VF, Outtrim J, Gee GS, Lupson V, Smith R, Aigbirhio FI, Fryer TD, Hong YT, Menon DK, Coles JP.

JAMA Neurol. 2016 May 1;73(5):542-50. doi: 10.1001/jamaneurol.2016.0091.

PMID:
27019039
23.

Normobaric hyperoxia markedly reduces brain damage and sensorimotor deficits following brief focal ischaemia.

Ejaz S, Emmrich JV, Sitnikov SL, Hong YT, Sawiak SJ, Fryer TD, Aigbirhio FI, Williamson DJ, Baron JC.

Brain. 2016 Mar;139(Pt 3):751-64. doi: 10.1093/brain/awv391. Epub 2016 Jan 14.

PMID:
26767570
24.

Early-Phase 11C-PiB PET in Amyloid Angiopathy-Related Symptomatic Cerebral Hemorrhage: Potential Diagnostic Value?

Farid K, Hong YT, Aigbirhio FI, Fryer TD, Menon DK, Warburton EA, Baron JC.

PLoS One. 2015 Oct 6;10(10):e0139926. doi: 10.1371/journal.pone.0139926. eCollection 2015.

25.

The pattern of amyloid accumulation in the brains of adults with Down syndrome.

Annus T, Wilson LR, Hong YT, Acosta-Cabronero J, Fryer TD, Cardenas-Blanco A, Smith R, Boros I, Coles JP, Aigbirhio FI, Menon DK, Zaman SH, Nestor PJ, Holland AJ.

Alzheimers Dement. 2016 May;12(5):538-45. doi: 10.1016/j.jalz.2015.07.490. Epub 2015 Sep 9.

26.

Synthesis and Initial in Vivo Studies with [(11)C]SB-216763: The First Radiolabeled Brain Penetrative Inhibitor of GSK-3.

Li L, Shao X, Cole EL, Ohnmacht SA, Ferrari V, Hong YT, Williamson DJ, Fryer TD, Quesada CA, Sherman P, Riss PJ, Scott PJ, Aigbirhio FI.

ACS Med Chem Lett. 2015 Mar 10;6(5):548-52. doi: 10.1021/acsmedchemlett.5b00044. eCollection 2015 May 14.

27.

White matter perivascular spaces on magnetic resonance imaging: marker of cerebrovascular amyloid burden?

Charidimou A, Hong YT, Jäger HR, Fox Z, Aigbirhio FI, Fryer TD, Menon DK, Warburton EA, Werring DJ, Baron JC.

Stroke. 2015 Jun;46(6):1707-9. doi: 10.1161/STROKEAHA.115.009090. Epub 2015 Apr 23.

PMID:
25908461
28.

Dissociable rate-dependent effects of oral methylphenidate on impulsivity and D2/3 receptor availability in the striatum.

Caprioli D, Jupp B, Hong YT, Sawiak SJ, Ferrari V, Wharton L, Williamson DJ, McNabb C, Berry D, Aigbirhio FI, Robbins TW, Fryer TD, Dalley JW.

J Neurosci. 2015 Mar 4;35(9):3747-55. doi: 10.1523/JNEUROSCI.3890-14.2015.

29.

Orbitofrontal dopamine depletion upregulates caudate dopamine and alters behavior via changes in reinforcement sensitivity.

Clarke HF, Cardinal RN, Rygula R, Hong YT, Fryer TD, Sawiak SJ, Ferrari V, Cockcroft G, Aigbirhio FI, Robbins TW, Roberts AC.

J Neurosci. 2014 May 28;34(22):7663-76. doi: 10.1523/JNEUROSCI.0718-14.2014.

30.

Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage.

Baron JC, Farid K, Dolan E, Turc G, Marrapu ST, O'Brien E, Aigbirhio FI, Fryer TD, Menon DK, Warburton EA, Hong YT.

J Cereb Blood Flow Metab. 2014 May;34(5):753-8. doi: 10.1038/jcbfm.2014.43. Epub 2014 Mar 12.

31.

Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.

Hong YT, Veenith T, Dewar D, Outtrim JG, Mani V, Williams C, Pimlott S, Hutchinson PJ, Tavares A, Canales R, Mathis CA, Klunk WE, Aigbirhio FI, Coles JP, Baron JC, Pickard JD, Fryer TD, Stewart W, Menon DK.

JAMA Neurol. 2014 Jan;71(1):23-31. doi: 10.1001/jamaneurol.2013.4847.

32.

A positron emission tomography study of nigro-striatal dopaminergic mechanisms underlying attention: implications for ADHD and its treatment.

del Campo N, Fryer TD, Hong YT, Smith R, Brichard L, Acosta-Cabronero J, Chamberlain SR, Tait R, Izquierdo D, Regenthal R, Dowson J, Suckling J, Baron JC, Aigbirhio FI, Robbins TW, Sahakian BJ, Müller U.

Brain. 2013 Nov;136(Pt 11):3252-70. doi: 10.1093/brain/awt263.

33.

Diffusion and perfusion correlates of the 18F-MISO PET lesion in acute stroke: pilot study.

Alawneh JA, Moustafa RR, Marrapu ST, Jensen-Kondering U, Morris RS, Jones PS, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC.

Eur J Nucl Med Mol Imaging. 2014 Apr;41(4):736-44. doi: 10.1007/s00259-013-2581-x. Epub 2013 Oct 15.

PMID:
24126468
34.

Is neural activation within the rescued penumbra impeded by selective neuronal loss?

Carrera E, Jones PS, Morris RS, Alawneh J, Hong YT, Aigbirhio FI, Fryer TD, Carpenter TA, Warburton EA, Baron JC.

Brain. 2013 Jun;136(Pt 6):1816-29. doi: 10.1093/brain/awt112. Epub 2013 May 16.

PMID:
23682070
35.

Translating positron emission tomography studies in animals to stimulant addiction: promises and pitfalls.

Caprioli D, Fryer TD, Sawiak SJ, Aigbirhio FI, Dalley JW.

Curr Opin Neurobiol. 2013 Aug;23(4):597-606. doi: 10.1016/j.conb.2013.04.003. Epub 2013 May 9. Review.

PMID:
23664005
36.

Baseline-dependent effects of cocaine pre-exposure on impulsivity and D2/3 receptor availability in the rat striatum: possible relevance to the attention-deficit hyperactivity syndrome.

Caprioli D, Hong YT, Sawiak SJ, Ferrari V, Williamson DJ, Jupp B, Adrian Carpenter T, Aigbirhio FI, Everitt BJ, Robbins TW, Fryer TD, Dalley JW.

Neuropsychopharmacology. 2013 Jul;38(8):1460-71. doi: 10.1038/npp.2013.44. Epub 2013 Feb 11.

37.

Synthesis and evaluation of 18F-FE-PEO in rodents: an 18F-labeled full agonist for opioid receptor imaging.

Riss PJ, Hong YT, Marton J, Caprioli D, Williamson DJ, Ferrari V, Saigal N, Roth BL, Henriksen G, Fryer TD, Dalley JW, Aigbirhio FI.

J Nucl Med. 2013 Feb;54(2):299-305. doi: 10.2967/jnumed.112.108688. Epub 2013 Jan 7.

38.

A comparison of four PET tracers for brain hypoxia mapping in a rodent model of stroke.

Williamson DJ, Ejaz S, Sitnikov S, Fryer TD, Sawiak SJ, Burke P, Baron JC, Aigbirhio FI.

Nucl Med Biol. 2013 Apr;40(3):338-44. doi: 10.1016/j.nucmedbio.2012.11.012. Epub 2013 Jan 5.

PMID:
23294900
39.

Characterizing infarction and selective neuronal loss following temporary focal cerebral ischemia in the rat: a multi-modality imaging study.

Ejaz S, Williamson DJ, Ahmed T, Sitnikov S, Hong YT, Sawiak SJ, Fryer TD, Aigbirhio FI, Baron JC.

Neurobiol Dis. 2013 Mar;51:120-32. doi: 10.1016/j.nbd.2012.11.002. Epub 2012 Nov 10.

PMID:
23146994
40.

The relationship of topographical memory performance to regional neurodegeneration in Alzheimer's disease.

Pengas G, Williams GB, Acosta-Cabronero J, Ash TW, Hong YT, Izquierdo-Garcia D, Fryer TD, Hodges JR, Nestor PJ.

Front Aging Neurosci. 2012 Jul 4;4:17. doi: 10.3389/fnagi.2012.00017. eCollection 2012.

41.

Dynamic in vivo imaging of receptors in small animals using positron emission tomography.

Johnström P, Fryer TD, Bird JL, Richards HK, Davenport AP.

Methods Mol Biol. 2012;897:221-37. doi: 10.1007/978-1-61779-909-9_11.

PMID:
22674168
42.

Registration-weighted motion correction for PET.

Dikaios N, Fryer TD.

Med Phys. 2012 Mar;39(3):1253-64. doi: 10.1118/1.3675922.

PMID:
22380357
43.

Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders.

Virdee K, Cumming P, Caprioli D, Jupp B, Rominger A, Aigbirhio FI, Fryer TD, Riss PJ, Dalley JW.

Neurosci Biobehav Rev. 2012 Apr;36(4):1188-216. doi: 10.1016/j.neubiorev.2012.01.009. Epub 2012 Feb 8. Review.

PMID:
22342372
44.

A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation.

Hughes JL, Jones PS, Beech JS, Wang D, Menon DK, Aigbirhio FI, Fryer TD, Baron JC.

Neuroimage. 2012 Feb 1;59(3):2007-16. doi: 10.1016/j.neuroimage.2011.10.060. Epub 2011 Oct 25.

PMID:
22056528
45.
46.

MRI-based motion correction of thoracic PET: initial comparison of acquisition protocols and correction strategies suitable for simultaneous PET/MRI systems.

Dikaios N, Izquierdo-Garcia D, Graves MJ, Mani V, Fayad ZA, Fryer TD.

Eur Radiol. 2012 Feb;22(2):439-46. doi: 10.1007/s00330-011-2274-4. Epub 2011 Sep 22.

47.

Microembolism versus hemodynamic impairment in rosary-like deep watershed infarcts: a combined positron emission tomography and transcranial Doppler study.

Moustafa RR, Momjian-Mayor I, Jones PS, Morbelli S, Day DJ, Aigbirhio FI, Fryer TD, Warburton EA, Baron JC.

Stroke. 2011 Nov;42(11):3138-43. doi: 10.1161/STROKEAHA.111.616334. Epub 2011 Aug 18.

PMID:
21852602
48.

Validation and quantification of [18F]altanserin binding in the rat brain using blood input and reference tissue modeling.

Riss PJ, Hong YT, Williamson D, Caprioli D, Sitnikov S, Ferrari V, Sawiak SJ, Baron JC, Dalley JW, Fryer TD, Aigbirhio FI.

J Cereb Blood Flow Metab. 2011 Dec;31(12):2334-42. doi: 10.1038/jcbfm.2011.94. Epub 2011 Jul 13.

49.

Attenuation correction methods suitable for brain imaging with a PET/MRI scanner: a comparison of tissue atlas and template attenuation map approaches.

Malone IB, Ansorge RE, Williams GB, Nestor PJ, Carpenter TA, Fryer TD.

J Nucl Med. 2011 Jul;52(7):1142-9. doi: 10.2967/jnumed.110.085076.

50.

Atrophy, hypometabolism and white matter abnormalities in semantic dementia tell a coherent story.

Acosta-Cabronero J, Patterson K, Fryer TD, Hodges JR, Pengas G, Williams GB, Nestor PJ.

Brain. 2011 Jul;134(Pt 7):2025-35. doi: 10.1093/brain/awr119. Epub 2011 Jun 6.

PMID:
21646331

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