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Items: 1 to 50 of 197

1.

Investigating cortisol excess or deficiency: a practical approach.

Hanna FWF, Issa BG, Kevil B, Fryer AA.

BMJ. 2019 Nov 26;367:l6039. doi: 10.1136/bmj.l6039. No abstract available.

PMID:
31771937
2.

The costs of drug prescriptions for diabetes in the NHS.

Stedman M, Lunt M, Livingston M, Fryer AA, Moreno G, Bailey S, Gadsby R, Heald A.

Lancet. 2019 Jan 19;393(10168):226-227. doi: 10.1016/S0140-6736(18)33190-8. No abstract available.

PMID:
30663590
3.

The frequency of testing for glycated haemoglobin, HbA1c, is linked to the probability of achieving target levels in patients with suboptimally controlled diabetes mellitus.

Duff CJ, Solis-Trapala I, Driskell OJ, Holland D, Wright H, Waldron JL, Ford C, Scargill JJ, Tran M, Hanna FWF, Pemberton RJ, Heald A, Fryer AA.

Clin Chem Lab Med. 2018 Dec 19;57(2):296-304. doi: 10.1515/cclm-2018-0503.

PMID:
30281512
4.

More frequent lithium testing in UK Primary Care associates with a lower hospital admission rate for bipolar disorder-What this can tell us about GP practice engagement with this group.

Holland D, Duff CJ, Farman S, Fryer AA, Yung A, Bailey S, Heald AH.

Int J Clin Pract. 2019 Apr;73(4):e13277. doi: 10.1111/ijcp.13277. No abstract available.

PMID:
30257075
5.

The association of sex hormone-binding globulin with mortality is mediated by age and testosterone in men with type 2 diabetes.

Ramachandran S, Strange RC, Fryer AA, Saad F, Hackett GI.

Andrology. 2018 Nov;6(6):846-853. doi: 10.1111/andr.12520. Epub 2018 Jul 13.

6.

Reduction of unnecessary N-terminal pro-brain natriuretic peptide (NT-proBNP) tests: A further lesson in demand management.

Livingston M, Kalansooriya A, Hartland A, Fryer AA, Gupta J, Heald AH.

Int J Clin Pract. 2018 Apr;72(4):e13071. doi: 10.1111/ijcp.13071. No abstract available.

PMID:
29878475
7.

Photodynamic therapy corrects abnormal cancer-associated gene expression observed in actinic keratosis lesions and induces a remodeling effect in photodamaged skin.

Joly F, Deret S, Gamboa B, Menigot C, Fogel P, Mounier C, Reiniche P, Sidou F, Aubert J, Lear J, Fryer AA, Zolezzi F, Voegel JJ.

J Dermatol Sci. 2018 May 17. pii: S0923-1811(17)30775-2. doi: 10.1016/j.jdermsci.2018.05.002. [Epub ahead of print]

PMID:
29779986
8.

Sodium-glucose co-transporter-2 inhibitors, the latest residents on the block: Impact on glycaemic control at a general practice level in England.

Heald AH, Fryer AA, Anderson SG, Livingston M, Lunt M, Davies M, Moreno GYC, Gadsby R, Young RJ, Stedman M.

Diabetes Obes Metab. 2018 Jul;20(7):1659-1669. doi: 10.1111/dom.13281. Epub 2018 Apr 17.

PMID:
29516618
9.

Should we be screening for thyroid dysfunction in patients with type 2 diabetes mellitus?

Ward RJ, Heald AH, Ogunmekan S, Fryer AA, Duff CJ.

Br J Gen Pract. 2018 Feb;68(667):94-95. doi: 10.3399/bjgp18X694793. No abstract available.

10.

Management of incidental adrenal tumours.

Hanna FWF, Issa BG, Sim J, Keevil B, Fryer AA.

BMJ. 2018 Jan 18;360:j5674. doi: 10.1136/bmj.j5674. No abstract available.

PMID:
29348269
11.

HumanMethylation450K Array-Identified Biomarkers Predict Tumour Recurrence/Progression at Initial Diagnosis of High-risk Non-muscle Invasive Bladder Cancer.

Kitchen MO, Bryan RT, Emes RD, Luscombe CJ, Cheng KK, Zeegers MP, James ND, Gommersall LM, Fryer AA.

Biomark Cancer. 2018 Jan 8;10:1179299X17751920. doi: 10.1177/1179299X17751920. eCollection 2018.

12.

Polycystic ovarian syndrome: Assessment of approaches to diagnosis and cardiometabolic monitoring in UK primary care.

Heald AH, Livingston M, Holland D, Robinson J, Moreno GY, Donnahey G, Duff CJ, Wu P, Fryer AA.

Int J Clin Pract. 2018 Jan;72(1). doi: 10.1111/ijcp.13046. Epub 2017 Dec 22.

PMID:
29271548
13.

Polycystic ovarian syndrome: Social situation influences outcome.

Livingston M, Holland D, Kalansooriya A, Moreno GY, Donnahey G, Duff CJ, Wu P, Fryer AA, Heald AH.

Int J Clin Pract. 2017 Aug;71(8). doi: 10.1111/ijcp.12981. No abstract available.

PMID:
28836360
14.

Improving type 2 diabetes mellitus glycaemic outcomes is possible without spending more on medication: Lessons from the UK National Diabetes Audit.

Heald AH, Livingston M, Malipatil N, Becher M, Craig J, Stedman M, Fryer AA.

Diabetes Obes Metab. 2018 Jan;20(1):185-194. doi: 10.1111/dom.13067. Epub 2017 Sep 8.

PMID:
28730750
15.

Social Disadvantage Is Associated With Lower Vitamin D Levels in Older People and There Is No Surrogate for Its Measurement.

Heald AH, Anderson SG, Scargill JJ, Short A, Holland D, Khan A, Fryer AA, Donn RP, Livingston M.

Gerontol Geriatr Med. 2017 Mar 28;3:2333721417697843. doi: 10.1177/2333721417697843. eCollection 2017 Jan-Dec.

16.

Socioeconomic Deprivation as Measured by the Index of Multiple Deprivation and Its Association with Low Sex Hormone Binding Globulin in Women.

Heald A, Laing I, McLernon DJ, Donn R, Hartland AJ, Fryer AA, Livingston M.

Open Biochem J. 2017 Mar 13;11:1-7. doi: 10.2174/1874091X01711010001. eCollection 2017.

17.

Monitoring Thyroid Function in Patients on Levothyroxine. Assessment of Conformity to National Guidance and Variability in Practice.

Scargill JJ, Livingston M, Holland D, Duff CJ, Fryer AA, Heald AH.

Exp Clin Endocrinol Diabetes. 2017 Oct;125(9):625-633. doi: 10.1055/s-0043-103018. Epub 2017 Apr 13.

PMID:
28407667
18.

Diagnosing gestational diabetes mellitus: implications of recent changes in diagnostic criteria and role of glycated haemoglobin (HbA1c).

Hanna FW, Duff CJ, Shelley-Hitchen A, Hodgson E, Fryer AA.

Clin Med (Lond). 2017 Apr;17(2):108-113. doi: 10.7861/clinmedicine.17-2-108.

19.

Preeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.

Wu P, Haththotuwa R, Kwok CS, Babu A, Kotronias RA, Rushton C, Zaman A, Fryer AA, Kadam U, Chew-Graham CA, Mamas MA.

Circ Cardiovasc Qual Outcomes. 2017 Feb;10(2). pii: e003497. doi: 10.1161/CIRCOUTCOMES.116.003497. Epub 2017 Feb 22. Review.

PMID:
28228456
20.

Monitoring thyroid function in patients on levothyroxine: audit findings and suggested change in practice.

Scargill JJ, Livingston M, Holland D, Khan A, Duff CJ, Fryer AA, Heald AH.

Int J Clin Pract. 2017 Jan;71(1). doi: 10.1111/ijcp.12877. No abstract available.

PMID:
28097763
21.

DNA methylation at diagnosis is associated with response to disease-modifying drugs in early rheumatoid arthritis.

Glossop JR, Nixon NB, Emes RD, Sim J, Packham JC, Mattey DL, Farrell WE, Fryer AA.

Epigenomics. 2017 Apr;9(4):419-428. doi: 10.2217/epi-2016-0042. Epub 2016 Nov 25.

PMID:
27885849
22.

Relationship Between Anemia and Mortality Outcomes in a National Acute Coronary Syndrome Cohort: Insights From the UK Myocardial Ischemia National Audit Project Registry.

Mamas MA, Kwok CS, Kontopantelis E, Fryer AA, Buchan I, Bachmann MO, Zaman MJ, Myint PK.

J Am Heart Assoc. 2016 Nov 19;5(11). pii: e003348.

23.

Pre-eclampsia is associated with a twofold increase in diabetes: a systematic review and meta-analysis.

Wu P, Kwok CS, Haththotuwa R, Kotronias RA, Babu A, Fryer AA, Myint PK, Chew-Graham CA, Mamas MA.

Diabetologia. 2016 Dec;59(12):2518-2526. Epub 2016 Sep 19. Review.

24.

Maternal genome-wide DNA methylation profiling in gestational diabetes shows distinctive disease-associated changes relative to matched healthy pregnancies.

Wu P, Farrell WE, Haworth KE, Emes RD, Kitchen MO, Glossop JR, Hanna FW, Fryer AA.

Epigenetics. 2018;13(2):122-128. doi: 10.1080/15592294.2016.1166321. Epub 2018 Jan 25.

25.

Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer.

Kitchen MO, Bryan RT, Emes RD, Glossop JR, Luscombe C, Cheng KK, Zeegers MP, James ND, Devall AJ, Mein CA, Gommersall L, Fryer AA, Farrell WE.

Epigenetics. 2016 Mar 3;11(3):237-46. doi: 10.1080/15592294.2016.1154246. Epub 2016 Mar 1.

26.

Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes.

Glossop JR, Emes RD, Nixon NB, Packham JC, Fryer AA, Mattey DL, Farrell WE.

Epigenomics. 2016 Feb;8(2):209-24. doi: 10.2217/epi.15.103. Epub 2015 Nov 10.

PMID:
26556652
27.

Are cholesterol levels being checked and managed appropriately in UK primary care type 2 diabetes?

Livingston M, Robinson JC, Brown CE, Narayanan RP, Holland D, Fryer AA, Heald AH.

Int J Clin Pract. 2015 Nov;69(11):1389-91. doi: 10.1111/ijcp.12717. No abstract available.

PMID:
26503576
28.

Methylation of HOXA9 and ISL1 Predicts Patient Outcome in High-Grade Non-Invasive Bladder Cancer.

Kitchen MO, Bryan RT, Haworth KE, Emes RD, Luscombe C, Gommersall L, Cheng KK, Zeegers MP, James ND, Devall AJ, Fryer AA, Farrell WE.

PLoS One. 2015 Sep 2;10(9):e0137003. doi: 10.1371/journal.pone.0137003. eCollection 2015.

29.

DNA methylation profiling of synovial fluid FLS in rheumatoid arthritis reveals changes common with tissue-derived FLS.

Glossop JR, Haworth KE, Emes RD, Nixon NB, Packham JC, Dawes PT, Fryer AA, Mattey DL, Farrell WE.

Epigenomics. 2015;7(4):539-51. doi: 10.2217/epi.15.15.

PMID:
26111028
30.

Revisiting screening for type 2 diabetes mellitus: the case for and against using HbA1c.

Hanna FW, Wilkie V, Issa BG, Fryer AA.

Br J Gen Pract. 2015 Apr;65(633):e278-80. doi: 10.3399/bjgp15X684637. No abstract available.

31.

Methylation of the FGFR2 gene is associated with high birth weight centile in humans.

Haworth KE, Farrell WE, Emes RD, Ismail KM, Carroll WD, Hubball E, Rooney A, Yates AM, Mein C, Fryer AA.

Epigenomics. 2014;6(5):477-91. doi: 10.2217/epi.14.40. Review.

PMID:
25431941
32.

Measuring vitamin D levels: surrogates are insufficient.

Heald AH, Anderson SG, Scargill JJ, Short AD, Holland D, Livingston M, Fryer AA, Donn RP.

Int J Clin Pract. 2015 Jan;69(1):131-5. doi: 10.1111/ijcp.12505. Epub 2014 Oct 31.

PMID:
25359317
33.

Reduced testing frequency for glycated hemoglobin, HbA1c, is associated with deteriorating diabetes control.

Driskell OJ, Holland D, Waldron JL, Ford C, Scargill JJ, Heald A, Tran M, Hanna FW, Jones PW, Pemberton RJ, Fryer AA.

Diabetes Care. 2014 Oct;37(10):2731-7. doi: 10.2337/dc14-0297.

PMID:
25249670
34.

Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations.

Glossop JR, Emes RD, Nixon NB, Haworth KE, Packham JC, Dawes PT, Fryer AA, Mattey DL, Farrell WE.

Epigenetics. 2014 Sep;9(9):1228-37. doi: 10.4161/epi.29718. Epub 2014 Jul 7.

35.

Epigenome-wide profiling identifies significant differences in DNA methylation between matched-pairs of T- and B-lymphocytes from healthy individuals.

Glossop JR, Nixon NB, Emes RD, Haworth KE, Packham JC, Dawes PT, Fryer AA, Mattey DL, Farrell WE.

Epigenetics. 2013 Nov;8(11):1188-97. doi: 10.4161/epi.26265. Epub 2013 Sep 4.

PMID:
24005183
36.

Combined influence of gene-specific cord blood methylation and maternal smoking habit on birth weight.

Haworth KE, Farrell WE, Emes RD, Ismail KM, Carroll WD, Borthwick HA, Yates AM, Hubball E, Rooney A, Khanam M, Aggarwal N, Jones PW, Fryer AA.

Epigenomics. 2013 Feb;5(1):37-49. doi: 10.2217/epi.12.72.

PMID:
23414319
37.

Antiepileptic drugs and the fetal epigenome.

Emes RD, Clifford H, Haworth KE, Farrell WE, Fryer AA, Carroll WD, Ismail KM.

Epilepsia. 2013 Jan;54(1):e16-9. doi: 10.1111/j.1528-1167.2012.03673.x. Epub 2012 Sep 27.

38.

Managing demand for laboratory tests: a laboratory toolkit.

Fryer AA, Smellie WS.

J Clin Pathol. 2013 Jan;66(1):62-72. doi: 10.1136/jclinpath-2011-200524. Epub 2012 Sep 26.

PMID:
23015659
39.

Inappropriate requesting of glycated hemoglobin (Hb A1c) is widespread: assessment of prevalence, impact of national guidance, and practice-to-practice variability.

Driskell OJ, Holland D, Hanna FW, Jones PW, Pemberton RJ, Tran M, Fryer AA.

Clin Chem. 2012 May;58(5):906-15. doi: 10.1373/clinchem.2011.176487. Epub 2012 Feb 16.

40.

Can volatile compounds in exhaled breath be used to monitor control in diabetes mellitus?

Smith D, Spaněl P, Fryer AA, Hanna F, Ferns GA.

J Breath Res. 2011 Jun;5(2):022001. doi: 10.1088/1752-7155/5/2/022001. Epub 2011 Apr 21. Review.

PMID:
21512208
41.

Predicting dysglycaemia in patients under investigation for acute coronary syndrome.

Tahrani AA, Geen J, Hanna FW, Jones PW, Cassidy D, Bates D, Fryer AA.

QJM. 2011 Mar;104(3):231-6. doi: 10.1093/qjmed/hcq184. Epub 2010 Oct 8.

PMID:
20934980
42.

Quantitative, high-resolution epigenetic profiling of CpG loci identifies associations with cord blood plasma homocysteine and birth weight in humans.

Fryer AA, Emes RD, Ismail KM, Haworth KE, Mein C, Carroll WD, Farrell WE.

Epigenetics. 2011 Jan;6(1):86-94. doi: 10.4161/epi.6.1.13392. Epub 2011 Jan 1.

43.

Analysis of the serotonin transporter promoter rs25531 polymorphism in premenstrual dysphoric disorder.

Magnay JL, El-Shourbagy M, Fryer AA, O'Brien S, Ismail KM.

Am J Obstet Gynecol. 2010 Aug;203(2):181.e1-5. doi: 10.1016/j.ajog.2010.02.043. Epub 2010 May 11.

PMID:
20462563
44.

Managing demand for pathology tests: financial imperative or duty of care?

Fryer AA, Hanna FW.

Ann Clin Biochem. 2009 Nov;46(Pt 6):435-7. doi: 10.1258/acb.2009.009186. Epub 2009 Oct 12. No abstract available.

PMID:
19822696
45.

LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: a preliminary study.

Fryer AA, Nafee TM, Ismail KM, Carroll WD, Emes RD, Farrell WE.

Epigenetics. 2009 Aug 16;4(6):394-8. Epub 2009 Aug 18.

PMID:
19755846
46.

Predicting risk of nonmelanoma skin cancer and premalignant skin lesions in renal transplant recipients.

Urwin HR, Jones PW, Harden PN, Ramsay HM, Hawley CM, Nicol DL, Fryer AA.

Transplantation. 2009 Jun 15;87(11):1667-71. doi: 10.1097/TP.0b013e3181a5ce2e.

PMID:
19502958
47.

Fibrillin 1 gene with R2726W mutation is absent in patients with primary protrusio acetabuli and developmental dysplasia of the hip.

Ghosh S, Fryer AA, Hoban PR, Wynn-Jones C, Maffulli N.

Med Sci Monit. 2009 May;15(5):CR199-202.

PMID:
19396033
48.

The rise and fall of C-reactive protein: managing demand within clinical biochemistry.

Hutton HD, Drummond HS, Fryer AA.

Ann Clin Biochem. 2009 Mar;46(Pt 2):155-8. doi: 10.1258/acb.2008.008126. Epub 2009 Jan 22.

PMID:
19164341
49.

A protective effect of glutathione-S-transferase GSTP1*Val(105) against polymorphic light eruption.

Millard TP, Fryer AA, McGregor JM.

J Invest Dermatol. 2008 Aug;128(8):1901-5. doi: 10.1038/jid.2008.14. Epub 2008 Feb 21.

50.

Associations between timing of exposure to ultraviolet radiation, T-stage and survival in prostate cancer.

Rukin N, Blagojevic M, Luscombe CJ, Liu S, Saxby MF, Ramachandran S, Fryer AA, Jones PW, Strange RC.

Cancer Detect Prev. 2007;31(6):443-9.

PMID:
18061372

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