Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 622


A Comparative Study of Mitochondrial Respiration in Circulating Blood Cells and Skeletal Muscle Fibers in Women.

Rose S, Carvalho E, Diaz EC, Cotter M, Bennuri SC, Azhar G, Frye RE, Adams SH, Børsheim E.

Am J Physiol Endocrinol Metab. 2019 Jun 18. doi: 10.1152/ajpendo.00084.2019. [Epub ahead of print]


Clustering of co-occurring conditions in autism spectrum disorder during early childhood: A retrospective analysis of medical claims data.

Vargason T, Frye RE, McGuinness DL, Hahn J.

Autism Res. 2019 Aug;12(8):1272-1285. doi: 10.1002/aur.2128. Epub 2019 May 31.


Mitochondrial Dysfunction Is Inducible in Lymphoblastoid Cell Lines From Children With Autism and May Involve the TORC1 Pathway.

Bennuri SC, Rose S, Frye RE.

Front Psychiatry. 2019 May 7;10:269. doi: 10.3389/fpsyt.2019.00269. eCollection 2019.


Left ventricular ejection hemodynamics before and after relief of outflow tract obstruction in patients with hypertrophic obstructive cardiomyopathy and valvular aortic stenosis.

Cui H, Schaff HV, Abel MD, Helder MRK, Frye RL, Ommen SR, Nishimura RA.

J Thorac Cardiovasc Surg. 2019 Apr 4. pii: S0022-5223(19)30749-4. doi: 10.1016/j.jtcvs.2019.03.071. [Epub ahead of print]


Increasing awareness of a quality control problem in aging gamma cameras.

Frye SA, Frye RJ, Sterkel B, Muzaffar R, Osman MM.

J Nucl Med Technol. 2019 Apr 24. pii: jnmt.118.222489. doi: 10.2967/jnmt.118.222489. [Epub ahead of print]


Nuclear Peroxisome Proliferator-Activated Receptors (PPARs) as Therapeutic Targets of Resveratrol for Autism Spectrum Disorder.

Barone R, Rizzo R, Tabbì G, Malaguarnera M, Frye RE, Bastin J.

Int J Mol Sci. 2019 Apr 16;20(8). pii: E1878. doi: 10.3390/ijms20081878. Review.


Effect of pterostilbene on in vitro drug metabolizing enzyme activity.

Albassam AA, Frye RF.

Saudi Pharm J. 2019 Mar;27(3):406-412. doi: 10.1016/j.jsps.2019.01.001. Epub 2019 Jan 7.


Reliability of the Cunningham Panel.

Frye RE, Shimasaki C.

Transl Psychiatry. 2019 Apr 8;9(1):129. doi: 10.1038/s41398-019-0462-1. No abstract available.


71-Year-Old Man Presenting With Postoperative Chest Tightness.

Ward RC, Prasad M, Frye RL.

Mayo Clin Proc. 2019 May;94(5):887-891. doi: 10.1016/j.mayocp.2018.08.044. Epub 2019 Apr 4. No abstract available.


Complex heterozygous polymerase gamma mutation and cerebral folate deficiency in a child with refractory partial status.

Samanta D, Ramakrishnaiah R, Frye RE.

Neurol India. 2019 Jan-Feb;67(1):259-260. doi: 10.4103/0028-3886.253623. No abstract available.


Shahbudin H. Rahimtoola, In Memoriam in 2 Parts: The Life, the Mentor.

Frye RL, Bax JJ.

J Am Coll Cardiol. 2019 Mar 12;73(9):1094-1096. doi: 10.1016/j.jacc.2019.02.001. No abstract available.


Variations in Mitochondrial Respiration Differ in IL-1ß/IL-10 Ratio Based Subgroups in Autism Spectrum Disorders.

Jyonouchi H, Geng L, Rose S, Bennuri SC, Frye RE.

Front Psychiatry. 2019 Feb 20;10:71. doi: 10.3389/fpsyt.2019.00071. eCollection 2019.


Dr Shahbudin H. Rahimtoola.

Frye RL.

Eur Heart J. 2019 Mar 14;40(11):865. doi: 10.1093/eurheartj/ehz075. No abstract available.


Rating of the Effectiveness of 26 Psychiatric and Seizure Medications for Autism Spectrum Disorder: Results of a National Survey.

Coleman DM, Adams JB, Anderson AL, Frye RE.

J Child Adolesc Psychopharmacol. 2019 Mar;29(2):107-123. doi: 10.1089/cap.2018.0121. Epub 2019 Feb 6.


Impact of Chronic Kidney Disease on Outcomes of Myocardial Revascularization in Patients With Diabetes.

Farkouh ME, Sidhu MS, Brooks MM, Vlachos H, Boden WE, Frye RL, Hartigan P, Siami FS, Bittner VA, Chaitman BR, Mancini GBJ, Fuster V.

J Am Coll Cardiol. 2019 Feb 5;73(4):400-411. doi: 10.1016/j.jacc.2018.11.044.


Comparison of Three Clinical Trial Treatments for Autism Spectrum Disorder Through Multivariate Analysis of Changes in Metabolic Profiles and Adaptive Behavior.

Vargason T, Kruger U, Roth E, Delhey LM, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ, Frye RE, Hahn J.

Front Cell Neurosci. 2018 Dec 19;12:503. doi: 10.3389/fncel.2018.00503. eCollection 2018.


A Subset of Patients With Autism Spectrum Disorders Show a Distinctive Metabolic Profile by Dried Blood Spot Analyses.

Barone R, Alaimo S, Messina M, Pulvirenti A, Bastin J; MIMIC-Autism Group, Ferro A, Frye RE, Rizzo R.

Front Psychiatry. 2018 Dec 7;9:636. doi: 10.3389/fpsyt.2018.00636. eCollection 2018.


Hypoglycemia and Elevated Troponin in Patients With Diabetes and Coronary Artery Disease.

Rezende PC, Everett BM, Brooks MM, Vlachos H, Orchard TJ, Frye RL, Bhatt DL, Hlatky MA.

J Am Coll Cardiol. 2018 Oct 9;72(15):1778-1786. doi: 10.1016/j.jacc.2018.07.067.


Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism.

Connery K, Tippett M, Delhey LM, Rose S, Slattery JC, Kahler SG, Hahn J, Kruger U, Cunningham MW, Shimasaki C, Frye RE.

Transl Psychiatry. 2018 Aug 10;8(1):148. doi: 10.1038/s41398-018-0214-7.


Multivariate techniques enable a biochemical classification of children with autism spectrum disorder versus typically-developing peers: A comparison and validation study.

Howsmon DP, Vargason T, Rubin RA, Delhey L, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ, Frye RE, Hahn J.

Bioeng Transl Med. 2018 Jun 19;3(2):156-165. doi: 10.1002/btm2.10095. eCollection 2018 May.


A Genetic Score Associates With Pioglitazone Response in Patients With Non-alcoholic Steatohepatitis.

Kawaguchi-Suzuki M, Cusi K, Bril F, Gong Y, Langaee T, Frye RF.

Front Pharmacol. 2018 Jul 17;9:752. doi: 10.3389/fphar.2018.00752. eCollection 2018.


Clinical and Molecular Characteristics of Mitochondrial Dysfunction in Autism Spectrum Disorder.

Rose S, Niyazov DM, Rossignol DA, Goldenthal M, Kahler SG, Frye RE.

Mol Diagn Ther. 2018 Oct;22(5):571-593. doi: 10.1007/s40291-018-0352-x. Review.


Impact of treatment strategies on outcomes in patients with stable coronary artery disease and type 2 diabetes mellitus according to presenting angina severity: A pooled analysis of three federally-funded randomized trials.

Mancini GBJ, Boden WE, Brooks MM, Vlachos H, Chaitman BR, Frye R, Bittner V, Hartigan PM, Dagenais GR.

Atherosclerosis. 2018 Oct;277:186-194. doi: 10.1016/j.atherosclerosis.2018.04.005. Epub 2018 Jun 1.


Transport of a manganese/zinc ethylene-bis-dithiocarbamate fungicide may involve pre-synaptic dopaminergic transporters.

Montgomery K, Corona C, Frye R, Barnett R, Bailey A, Fitsanakis VA.

Neurotoxicol Teratol. 2018 Jul - Aug;68:66-71. doi: 10.1016/ Epub 2018 May 26.


Pioglitazone improves hepatic mitochondrial function in a mouse model of nonalcoholic steatohepatitis.

Kalavalapalli S, Bril F, Koelmel JP, Abdo K, Guingab J, Andrews P, Li WY, Jose D, Yost RA, Frye RF, Garrett TJ, Cusi K, Sunny NE.

Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E163-E173. doi: 10.1152/ajpendo.00023.2018. Epub 2018 Apr 10.


Metabolomic association between venous thromboembolism in critically ill trauma patients and kynurenine pathway of tryptophan metabolism.

Voils SA, Shahin MH, Garrett TJ, Frye RF.

Thromb Res. 2018 May;165:6-13. doi: 10.1016/j.thromres.2018.03.003. Epub 2018 Mar 8.


Comparison of Treatment for Metabolic Disorders Associated with Autism:Reanalysis of Three Clinical Trials.

Delhey LM, Tippett M, Rose S, Bennuri SC, Slattery JC, Melnyk S, James SJ, Frye RE.

Front Neurosci. 2018 Feb 12;12:19. doi: 10.3389/fnins.2018.00019. eCollection 2018.


Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism.

Rose S, Bennuri SC, Davis JE, Wynne R, Slattery JC, Tippett M, Delhey L, Melnyk S, Kahler SG, MacFabe DF, Frye RE.

Transl Psychiatry. 2018 Feb 2;8(1):42. doi: 10.1038/s41398-017-0089-z.


Modulation of Immunological Pathways in Autistic and Neurotypical Lymphoblastoid Cell Lines by the Enteric Microbiome Metabolite Propionic Acid.

Frye RE, Nankova B, Bhattacharyya S, Rose S, Bennuri SC, MacFabe DF.

Front Immunol. 2017 Dec 22;8:1670. doi: 10.3389/fimmu.2017.01670. eCollection 2017.


Sphingolipid Metabolic Pathway Impacts Thiazide Diuretics Blood Pressure Response: Insights From Genomics, Metabolomics, and Lipidomics.

Shahin MH, Gong Y, Frye RF, Rotroff DM, Beitelshees AL, Baillie RA, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Motsinger-Reif A, Fiehn O, Cooper-DeHoff RM, Han X, Kaddurah-Daouk R, Johnson JA.

J Am Heart Assoc. 2017 Dec 29;7(1). pii: e006656. doi: 10.1161/JAHA.117.006656.


Relative Bioavailability of Silybin A and Silybin B From 2 Multiconstituent Dietary Supplement Formulations Containing Milk Thistle Extract: A Single-dose Study.

Li WY, Yu G, Hogan RM, Mohandas R, Frye RF, Gumpricht E, Markowitz JS.

Clin Ther. 2018 Jan;40(1):103-113.e1. doi: 10.1016/j.clinthera.2017.11.013. Epub 2017 Dec 19.


Response to Newman et al.

Parikh S, Goldstein A, Karaa A, Koenig MK, Anselm I, Brunel-Guitton C, Christodoulou J, Cohen BH, Dimmock D, Enns GM, Falk MJ, Feigenbaum A, Frye RE, Ganesh J, Griesemer D, Haas R, Horvath R, Korson M, Kruer MC, Mancuso M, McCormack S, Josee Raboisson M, Reimschisel T, Salvarinova R, Saneto RP, Scaglia F, Shoffner J, Stacpoole PW, Sue CM, Tarnopolsky M, Van Karnebeek C, Wolfe LA, Zolkipli Cunningham Z, Rahman S, Chinnery PF.

Genet Med. 2017 Dec;19(12). doi: 10.1038/gim.2017.164. Epub 2017 Oct 26. No abstract available.


High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.

Hamdan FF, Myers CT, Cossette P, Lemay P, Spiegelman D, Laporte AD, Nassif C, Diallo O, Monlong J, Cadieux-Dion M, Dobrzeniecka S, Meloche C, Retterer K, Cho MT, Rosenfeld JA, Bi W, Massicotte C, Miguet M, Brunga L, Regan BM, Mo K, Tam C, Schneider A, Hollingsworth G; Deciphering Developmental Disorders Study, FitzPatrick DR, Donaldson A, Canham N, Blair E, Kerr B, Fry AE, Thomas RH, Shelagh J, Hurst JA, Brittain H, Blyth M, Lebel RR, Gerkes EH, Davis-Keppen L, Stein Q, Chung WK, Dorison SJ, Benke PJ, Fassi E, Corsten-Janssen N, Kamsteeg EJ, Mau-Them FT, Bruel AL, Verloes A, Õunap K, Wojcik MH, Albert DVF, Venkateswaran S, Ware T, Jones D, Liu YC, Mohammad SS, Bizargity P, Bacino CA, Leuzzi V, Martinelli S, Dallapiccola B, Tartaglia M, Blumkin L, Wierenga KJ, Purcarin G, O'Byrne JJ, Stockler S, Lehman A, Keren B, Nougues MC, Mignot C, Auvin S, Nava C, Hiatt SM, Bebin M, Shao Y, Scaglia F, Lalani SR, Frye RE, Jarjour IT, Jacques S, Boucher RM, Riou E, Srour M, Carmant L, Lortie A, Major P, Diadori P, Dubeau F, D'Anjou G, Bourque G, Berkovic SF, Sadleir LG, Campeau PM, Kibar Z, Lafrenière RG, Girard SL, Mercimek-Mahmutoglu S, Boelman C, Rouleau GA, Scheffer IE, Mefford HC, Andrade DM, Rossignol E, Minassian BA, Michaud JL.

Am J Hum Genet. 2017 Nov 2;101(5):664-685. doi: 10.1016/j.ajhg.2017.09.008.


Autistic Siblings with Novel Mutations in Two Different Genes: Insight for Genetic Workups of Autistic Siblings and Connection to Mitochondrial Dysfunction.

Burger BJ, Rose S, Bennuri SC, Gill PS, Tippett ML, Delhey L, Melnyk S, Frye RE.

Front Pediatr. 2017 Oct 12;5:219. doi: 10.3389/fped.2017.00219. eCollection 2017.


Mitochondrial dysfunction in the gastrointestinal mucosa of children with autism: A blinded case-control study.

Rose S, Bennuri SC, Murray KF, Buie T, Winter H, Frye RE.

PLoS One. 2017 Oct 13;12(10):e0186377. doi: 10.1371/journal.pone.0186377. eCollection 2017.


Bioenergetic variation is related to autism symptomatology.

Delhey L, Kilinc EN, Yin L, Slattery J, Tippett M, Wynne R, Rose S, Kahler S, Damle S, Legido A, Goldenthal MJ, Frye RE.

Metab Brain Dis. 2017 Dec;32(6):2021-2031. doi: 10.1007/s11011-017-0087-0. Epub 2017 Aug 29.


Novel biomarkers of metabolic dysfunction is autism spectrum disorder: potential for biological diagnostic markers.

Khemakhem AM, Frye RE, El-Ansary A, Al-Ayadhi L, Bacha AB.

Metab Brain Dis. 2017 Dec;32(6):1983-1997. doi: 10.1007/s11011-017-0085-2. Epub 2017 Aug 22.


Folate metabolism abnormalities in autism: potential biomarkers.

Frye RE, Slattery JC, Quadros EV.

Biomark Med. 2017 Aug;11(8):687-699. doi: 10.2217/bmm-2017-0109. Epub 2017 Aug 3.


Patient care standards for primary mitochondrial disease: a consensus statement from the Mitochondrial Medicine Society.

Parikh S, Goldstein A, Karaa A, Koenig MK, Anselm I, Brunel-Guitton C, Christodoulou J, Cohen BH, Dimmock D, Enns GM, Falk MJ, Feigenbaum A, Frye RE, Ganesh J, Griesemer D, Haas R, Horvath R, Korson M, Kruer MC, Mancuso M, McCormack S, Raboisson MJ, Reimschisel T, Salvarinova R, Saneto RP, Scaglia F, Shoffner J, Stacpoole PW, Sue CM, Tarnopolsky M, Van Karnebeek C, Wolfe LA, Cunningham ZZ, Rahman S, Chinnery PF.

Genet Med. 2017 Dec;19(12). doi: 10.1038/gim.2017.107. Epub 2017 Jul 27. Review.


The Putative Role of Environmental Mercury in the Pathogenesis and Pathophysiology of Autism Spectrum Disorders and Subtypes.

Morris G, Puri BK, Frye RE, Maes M.

Mol Neurobiol. 2018 Jun;55(6):4834-4856. doi: 10.1007/s12035-017-0692-2. Epub 2017 Jul 22. Review.


Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines.

Frye RE, Rose S, Wynne R, Bennuri SC, Blossom S, Gilbert KM, Heilbrun L, Palmer RF.

Sci Rep. 2017 Jun 30;7(1):4478. doi: 10.1038/s41598-017-04821-3.


Multiarterial grafts improve the rate of early major adverse cardiac and cerebrovascular events in patients undergoing coronary revascularization: analysis of 12 615 patients with multivessel disease.

Locker C, Schaff HV, Daly RC, Bell MR, Frye RL, Stulak JM, Said SM, Dearani JA, Joyce LD, Greason KL, Pochettino A, Li Z, Lennon RJ, Lerman A.

Eur J Cardiothorac Surg. 2017 Oct 1;52(4):746-752. doi: 10.1093/ejcts/ezx171.


Concentration-dependent response to pioglitazone in nonalcoholic steatohepatitis.

Kawaguchi-Suzuki M, Bril F, Kalavalapalli S, Cusi K, Frye RF.

Aliment Pharmacol Ther. 2017 Jul;46(1):56-61. doi: 10.1111/apt.14111. Epub 2017 May 3.


The effect of milk thistle (Silybum marianum) and its main flavonolignans on CYP2C8 enzyme activity in human liver microsomes.

Albassam AA, Frye RF, Markowitz JS.

Chem Biol Interact. 2017 Jun 1;271:24-29. doi: 10.1016/j.cbi.2017.04.025. Epub 2017 Apr 27.


Presence of arachidonoyl-carnitine is associated with adverse cardiometabolic responses in hypertensive patients treated with atenolol.

Weng L, Gong Y, Culver J, Gardell SJ, Petucci C, Morse AM, Frye RF, Turner ST, Chapman A, Boerwinkle E, Gums J, Beitelshees AL, Borum PR, Johnson JA, Garrett TJ, McIntyre LM, Cooper-DeHoff RM.

Metabolomics. 2016 Oct;12(10). pii: 160. doi: 10.1007/s11306-016-1098-2. Epub 2016 Sep 15.


Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.

de Oliveira FA, Shahin MH, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Boerwinkle E, Turner ST, Frye RF, Fiehn O, Kaddurah-Daouk R, Johnson JA, Cooper-DeHoff RM.

Metabolomics. 2016 Aug;12(8). pii: 129. doi: 10.1007/s11306-016-1076-8. Epub 2016 Jul 13.


The Effect of Mitochondrial Supplements on Mitochondrial Activity in Children with Autism Spectrum Disorder.

Delhey LM, Nur Kilinc E, Yin L, Slattery JC, Tippett ML, Rose S, Bennuri SC, Kahler SG, Damle S, Legido A, Goldenthal MJ, Frye RE.

J Clin Med. 2017 Feb 13;6(2). pii: E18. doi: 10.3390/jcm6020018.

Supplemental Content

Support Center