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Items: 1 to 50 of 351

1.

Waning of measured influenza vaccine effectiveness over time: the potential contribution of leaky vaccine effect.

Tokars JI, Patel MM, Foppa IM, Reed C, Fry AM, Ferdinands JM.

Clin Infect Dis. 2020 Mar 28. pii: ciaa340. doi: 10.1093/cid/ciaa340. [Epub ahead of print]

PMID:
32227109
2.

EML4-ALK V3 oncogenic fusion proteins promote microtubule stabilization and accelerated migration through NEK9 and NEK7.

O'Regan L, Barone G, Adib R, Woo CG, Jeong HJ, Richardson EL, Richards MW, Muller PAJ, Collis SJ, Fennell DA, Choi J, Bayliss R, Fry AM.

J Cell Sci. 2020 Mar 17. pii: jcs.241505. doi: 10.1242/jcs.241505. [Epub ahead of print]

PMID:
32184261
3.

Active Monitoring of Persons Exposed to Patients with Confirmed COVID-19 - United States, January-February 2020.

Burke RM, Midgley CM, Dratch A, Fenstersheib M, Haupt T, Holshue M, Ghinai I, Jarashow MC, Lo J, McPherson TD, Rudman S, Scott S, Hall AJ, Fry AM, Rolfes MA.

MMWR Morb Mortal Wkly Rep. 2020 Mar 6;69(9):245-246. doi: 10.15585/mmwr.mm6909e1.

4.

Vaccine Effectiveness Against Influenza Hospitalization Among Children in the United States, 2015-2016.

Feldstein LR, Ogokeh C, Rha B, Weinberg GA, Staat MA, Selvarangan R, Halasa NB, Englund JA, Boom JA, Azimi PH, Szilagyi PG, McNeal M, Harrison CJ, Williams JV, Klein EJ, Sahni LC, Singer MN, Lively JY, Payne DC, Fry AM, Patel M, Campbell AP.

J Pediatric Infect Dis Soc. 2020 Feb 28. pii: piaa017. doi: 10.1093/jpids/piaa017. [Epub ahead of print]

PMID:
32108879
5.

Interim Estimates of 2019-20 Seasonal Influenza Vaccine Effectiveness - United States, February 2020.

Dawood FS, Chung JR, Kim SS, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, McLean HQ, Gaglani M, Dunnigan K, Foust A, Sessions W, DaSilva J, Le S, Stark T, Kondor RJ, Barnes JR, Wentworth DE, Brammer L, Fry AM, Patel MM, Flannery B.

MMWR Morb Mortal Wkly Rep. 2020 Feb 21;69(7):177-182. doi: 10.15585/mmwr.mm6907a1.

6.

Persons Evaluated for 2019 Novel Coronavirus - United States, January 2020.

Bajema KL, Oster AM, McGovern OL, Lindstrom S, Stenger MR, Anderson TC, Isenhour C, Clarke KR, Evans ME, Chu VT, Biggs HM, Kirking HL, Gerber SI, Hall AJ, Fry AM, Oliver SE; 2019-nCoV Persons Under Investigation Team; 2019-CoV Persons Under Investigation Team.

MMWR Morb Mortal Wkly Rep. 2020 Feb 14;69(6):166-170. doi: 10.15585/mmwr.mm6906e1.

7.

Effectiveness of Trivalent and Quadrivalent Inactivated Vaccines against Influenza B in the United States, 2011-2012 to 2016-2017.

Gaglani M, Vasudevan A, Raiyani C, Murthy K, Chen W, Reis M, Belongia EA, McLean HQ, Jackson ML, Jackson LA, Zimmerman RK, Nowalk MP, Monto AS, Martin ET, Chung JR, Spencer S, Fry AM, Flannery B.

Clin Infect Dis. 2020 Feb 1. pii: ciaa102. doi: 10.1093/cid/ciaa102. [Epub ahead of print]

PMID:
32006430
8.

Early season pediatric influenza B/Victoria virus infections associated with a recently emerged virus subclade - Louisiana, 2019.

Owusu D, Hand J, Tenforde MW, Feldstein LR, DaSilva J, Barnes J, Lee G, Tran J, Sokol T, Fry AM, Brammer L, Rolfes MA.

Am J Transplant. 2020 Feb;20(2):606-609. doi: 10.1111/ajt.15782. No abstract available.

PMID:
31983080
9.

Note to readers.

Rolfes MA, Reed C, Fry AM.

Clin Infect Dis. 2020 Jan 17. pii: ciaa045. doi: 10.1093/cid/ciaa045. [Epub ahead of print] No abstract available.

PMID:
31960898
10.

Early Season Pediatric Influenza B/Victoria Virus Infections Associated with a Recently Emerged Virus Subclade - Louisiana, 2019.

Owusu D, Hand J, Tenforde MW, Feldstein LR, DaSilva J, Barnes J, Lee G, Tran J, Sokol T, Fry AM, Brammer L, Rolfes MA.

MMWR Morb Mortal Wkly Rep. 2020 Jan 17;69(2):40-43. doi: 10.15585/mmwr.mm6902e1.

11.

Effects of Influenza Vaccination in the United States during the 2018-2019 Influenza Season.

Chung JR, Rolfes MA, Flannery B, Prasad P, O'Halloran A, Garg S, Fry AM, Singleton JA, Patel M, Reed C.

Clin Infect Dis. 2020 Jan 6. pii: ciz1244. doi: 10.1093/cid/ciz1244. [Epub ahead of print]

PMID:
31905401
12.

Comparative Immunogenicity of Several Enhanced Influenza Vaccine Options for Older Adults: A Randomized, Controlled Trial.

Cowling BJ, Perera RAPM, Valkenburg SA, Leung NHL, Iuliano AD, Tam YH, Wong JHF, Fang VJ, Li APY, So HC, Ip DKM, Azziz-Baumgartner E, Fry AM, Levine MZ, Gangappa S, Sambhara S, Barr IG, Skowronski DM, Peiris JSM, Thompson MG.

Clin Infect Dis. 2019 Dec 12. pii: ciz1034. doi: 10.1093/cid/ciz1034. [Epub ahead of print]

PMID:
31828291
13.

Priming with MF59 adjuvanted versus nonadjuvanted seasonal influenza vaccines in children - A systematic review and a meta-analysis.

Patel MM, Davis W, Beacham L, Spencer S, Campbell AP, Lafond K, Rolfes M, Levine MZ, Azziz-Baumgartner E, Thompson MG, Fry AM.

Vaccine. 2020 Jan 16;38(3):608-619. doi: 10.1016/j.vaccine.2019.10.053. Epub 2019 Nov 15.

PMID:
31735505
14.

Spread of Antigenically Drifted Influenza A(H3N2) Viruses and Vaccine Effectiveness in the United States During the 2018-2019 Season.

Flannery B, Kondor RJG, Chung JR, Gaglani M, Reis M, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, McLean HQ, Kim SS, Blanton L, Kniss K, Budd AP, Brammer L, Stark TJ, Barnes JR, Wentworth DE, Fry AM, Patel M.

J Infect Dis. 2020 Jan 1;221(1):8-15. doi: 10.1093/infdis/jiz543.

PMID:
31665373
15.

Update: Influenza Activity - United States and Worldwide, May 19-September 28, 2019, and Composition of the 2020 Southern Hemisphere Influenza Vaccine.

Epperson S, Davis CT, Brammer L, Abd Elal AI, Ajayi N, Barnes J, Budd AP, Burns E, Daly P, Dugan VG, Fry AM, Jang Y, Johnson SJ, Kniss K, Kondor R, Grohskopf LA, Gubareva L, Merced-Morales A, Sessions W, Stevens J, Wentworth DE, Xu X, Jernigan D.

MMWR Morb Mortal Wkly Rep. 2019 Oct 11;68(40):880-884. doi: 10.15585/mmwr.mm6840a3.

16.

Results of flap reconstruction: categorisation to reflect outcomes and process in the management of head and neck defects.

Ho MW, Nugent M, Puglia F, Shaw RJ, Blackburn TK, Parmar S, Dhanda J, Fry AM, Brennan P, Barry CP, McMahon J.

Br J Oral Maxillofac Surg. 2019 Nov;57(9):935-937. doi: 10.1016/j.bjoms.2019.08.005. Epub 2019 Aug 22.

PMID:
31447074
17.

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2019-20 Influenza Season.

Grohskopf LA, Alyanak E, Broder KR, Walter EB, Fry AM, Jernigan DB.

MMWR Recomm Rep. 2019 Aug 23;68(3):1-21. doi: 10.15585/mmwr.rr6803a1.

18.

Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression.

Adib R, Montgomery JM, Atherton J, O'Regan L, Richards MW, Straatman KR, Roth D, Straube A, Bayliss R, Moores CA, Fry AM.

Sci Signal. 2019 Aug 13;12(594). pii: eaaw2939. doi: 10.1126/scisignal.aaw2939.

19.

Vaccination history as a confounder of studies of influenza vaccine effectiveness.

Foppa IM, Ferdinands JM, Chung J, Flannery B, Fry AM.

Vaccine X. 2019 Jan 31;1:100008. doi: 10.1016/j.jvacx.2019.100008. eCollection 2019 Apr 11.

20.

Projected Population Benefit of Increased Effectiveness and Coverage of Influenza Vaccination on Influenza Burden - United States.

Hughes MM, Reed C, Flannery B, Garg S, Singleton JA, Fry AM, Rolfes MA.

Clin Infect Dis. 2019 Jul 25. pii: ciz676. doi: 10.1093/cid/ciz676. [Epub ahead of print]

PMID:
31344229
21.

Baloxavir and Treatment-Emergent Resistance: Public Health Insights and Next Steps.

Gubareva LV, Fry AM.

J Infect Dis. 2020 Jan 14;221(3):337-339. doi: 10.1093/infdis/jiz245. No abstract available.

PMID:
31309982
22.

Waning of influenza vaccine protection: Exploring the trade-offs of changes in vaccination timing among older adults.

Ferdinands JM, Alyanak E, Reed C, Fry AM.

Clin Infect Dis. 2019 Jun 29. pii: ciz452. doi: 10.1093/cid/ciz452. [Epub ahead of print]

PMID:
31257422
23.

Update: Influenza Activity in the United States During the 2018-19 Season and Composition of the 2019-20 Influenza Vaccine.

Xu X, Blanton L, Elal AIA, Alabi N, Barnes J, Biggerstaff M, Brammer L, Budd AP, Burns E, Cummings CN, Garg S, Kondor R, Gubareva L, Kniss K, Nyanseor S, O'Halloran A, Rolfes M, Sessions W, Dugan VG, Fry AM, Wentworth DE, Stevens J, Jernigan D.

MMWR Morb Mortal Wkly Rep. 2019 Jun 21;68(24):544-551. doi: 10.15585/mmwr.mm6824a3.

24.

Reply to Gonzales-Luna and Carlson.

Rolfes MA, Flannery B, Patel M, Reed C, Fry AM.

Clin Infect Dis. 2020 Jan 2;70(2):357-358. doi: 10.1093/cid/ciz428. No abstract available.

PMID:
31112216
25.

Birth Cohort Effects in Influenza Surveillance Data: Evidence That First Influenza Infection Affects Later Influenza-Associated Illness.

Budd AP, Beacham L, Smith CB, Garten RJ, Reed C, Kniss K, Mustaquim D, Ahmad FB, Cummings CN, Garg S, Levine MZ, Fry AM, Brammer L.

J Infect Dis. 2019 Jul 31;220(5):820-829. doi: 10.1093/infdis/jiz201.

PMID:
31053844
26.

Data resource profile: Household Influenza Vaccine Evaluation (HIVE) Study.

Monto AS, Malosh RE, Evans R, Lauring AS, Gordon A, Thompson MG, Fry AM, Flannery B, Ohmit SE, Petrie JG, Martin ET; HIVE Study Research Staff.

Int J Epidemiol. 2019 Aug 1;48(4):1040-1040g. doi: 10.1093/ije/dyz086. No abstract available.

27.

Text-Based Illness Monitoring for Detection of Novel Influenza A Virus Infections During an Influenza A (H3N2)v Virus Outbreak in Michigan, 2016: Surveillance and Survey.

Stewart RJ, Rossow J, Eckel S, Bidol S, Ballew G, Signs K, Conover JT, Burns E, Bresee JS, Fry AM, Olsen SJ, Biggerstaff M.

JMIR Public Health Surveill. 2019 Apr 26;5(2):e10842. doi: 10.2196/10842.

28.

Population-based Incidence of Childhood Pneumonia Associated With Viral Infections in Bangladesh.

Havers FP, Fry AM, Goswami D, Nahar K, Sharmin AT, Rahman M, Brooks WA.

Pediatr Infect Dis J. 2019 Apr;38(4):344-350. doi: 10.1097/INF.0000000000002155.

PMID:
30882722
29.

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.

Uyeki TM, Bernstein HH, Bradley JS, Englund JA, File TM, Fry AM, Gravenstein S, Hayden FG, Harper SA, Hirshon JM, Ison MG, Johnston BL, Knight SL, McGeer A, Riley LE, Wolfe CR, Alexander PE, Pavia AT.

Clin Infect Dis. 2019 Mar 5;68(6):895-902. doi: 10.1093/cid/ciy874. No abstract available.

30.

Interim Estimates of 2018-19 Seasonal Influenza Vaccine Effectiveness - United States, February 2019.

Doyle JD, Chung JR, Kim SS, Gaglani M, Raiyani C, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, McLean HQ, Foust A, Sessions W, Berman L, Garten RJ, Barnes JR, Wentworth DE, Fry AM, Patel MM, Flannery B.

MMWR Morb Mortal Wkly Rep. 2019 Feb 15;68(6):135-139. doi: 10.15585/mmwr.mm6806a2.

31.

Update: Influenza Activity - United States, September 30, 2018-February 2, 2019.

Blanton L, Dugan VG, Abd Elal AI, Alabi N, Barnes J, Brammer L, Budd AP, Burns E, Cummings CN, Garg S, Garten R, Gubareva L, Kniss K, Kramer N, O'Halloran A, Reed C, Rolfes M, Sessions W, Taylor C, Xu X, Fry AM, Wentworth DE, Katz J, Jernigan D.

MMWR Morb Mortal Wkly Rep. 2019 Feb 15;68(6):125-134. doi: 10.15585/mmwr.mm6806a1.

32.

Estimating Risk to Responders Exposed to Avian Influenza A H5 and H7 Viruses in Poultry, United States, 2014-2017.

Olsen SJ, Rooney JA, Blanton L, Rolfes MA, Nelson DI, Gomez TM, Karli SA, Trock SC, Fry AM.

Emerg Infect Dis. 2019 May;25(5):1011-1014. doi: 10.3201/eid2505.181253. Epub 2019 May 17.

33.

Effects of Influenza Vaccination in the United States During the 2017-2018 Influenza Season.

Rolfes MA, Flannery B, Chung JR, O'Halloran A, Garg S, Belongia EA, Gaglani M, Zimmerman RK, Jackson ML, Monto AS, Alden NB, Anderson E, Bennett NM, Billing L, Eckel S, Kirley PD, Lynfield R, Monroe ML, Spencer M, Spina N, Talbot HK, Thomas A, Torres SM, Yousey-Hindes K, Singleton JA, Patel M, Reed C, Fry AM; US Influenza Vaccine Effectiveness (Flu VE) Network, the Influenza Hospitalization Surveillance Network, and the Assessment Branch, Immunization Services Division, Centers for Disease Control and Prevention .

Clin Infect Dis. 2019 Nov 13;69(11):1845-1853. doi: 10.1093/cid/ciz075.

PMID:
30715278
34.

Assessing baloxavir susceptibility of influenza viruses circulating in the United States during the 2016/17 and 2017/18 seasons.

Gubareva LV, Mishin VP, Patel MC, Chesnokov A, Nguyen HT, De La Cruz J, Spencer S, Campbell AP, Sinner M, Reid H, Garten R, Katz JM, Fry AM, Barnes J, Wentworth DE.

Euro Surveill. 2019 Jan;24(3). doi: 10.2807/1560-7917.ES.2019.24.3.1800666.

35.

Outpatient Antibiotic Prescribing for Acute Respiratory Infections During Influenza Seasons.

Havers FP, Hicks LA, Chung JR, Gaglani M, Murthy K, Zimmerman RK, Jackson LA, Petrie JG, McLean HQ, Nowalk MP, Jackson ML, Monto AS, Belongia EA, Flannery B, Fry AM.

JAMA Netw Open. 2018 Jun 1;1(2):e180243. doi: 10.1001/jamanetworkopen.2018.0243.

36.

Live Attenuated and Inactivated Influenza Vaccine Effectiveness.

Chung JR, Flannery B, Ambrose CS, Bégué RE, Caspard H, DeMarcus L, Fowlkes AL, Kersellius G, Steffens A, Fry AM; Influenza Clinical Investigation for Children Study Team; Influenza Incidence Surveillance Project; US Influenza Vaccine Effectiveness Network.

Pediatrics. 2019 Feb;143(2). pii: e20182094. doi: 10.1542/peds.2018-2094. Epub 2019 Jan 7.

37.

Clinical Practice Guidelines by the Infectious Diseases Society of America: 2018 Update on Diagnosis, Treatment, Chemoprophylaxis, and Institutional Outbreak Management of Seasonal Influenzaa.

Uyeki TM, Bernstein HH, Bradley JS, Englund JA, File TM, Fry AM, Gravenstein S, Hayden FG, Harper SA, Hirshon JM, Ison MG, Johnston BL, Knight SL, McGeer A, Riley LE, Wolfe CR, Alexander PE, Pavia AT.

Clin Infect Dis. 2019 Mar 5;68(6):e1-e47. doi: 10.1093/cid/ciy866. Erratum in: Clin Infect Dis. 2019 May 2;68(10):1790.

38.

Comparing Influenza Vaccine Types: The Path Toward Improved Influenza Vaccine Strategies.

Flannery B, Fry AM.

J Infect Dis. 2019 Sep 13;220(8):1237-1239. doi: 10.1093/infdis/jiy717. No abstract available.

PMID:
30561690
39.

Prevention of Influenza Hospitalization Among Adults in the United States, 2015-2016: Results From the US Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN).

Ferdinands JM, Gaglani M, Martin ET, Middleton D, Monto AS, Murthy K, Silveira FP, Talbot HK, Zimmerman R, Alyanak E, Strickland C, Spencer S, Fry AM; HAIVEN Study Investigators .

J Infect Dis. 2019 Sep 13;220(8):1265-1275. doi: 10.1093/infdis/jiy723.

PMID:
30561689
40.

Influenza Vaccine Effectiveness.

Ferdinands JM, Patel MM, Foppa IM, Fry AM.

Clin Infect Dis. 2019 Jun 18;69(1):190-191. doi: 10.1093/cid/ciy1084. No abstract available.

PMID:
30561533
41.

Influenza Activity - United States, September 30-December 1, 2018.

Budd AP, Abd Elal AI, Alabi N, Barnes J, Blanton L, Brammer L, Burns E, Cummings CN, Dugan VG, Garg S, Garten R, Grohskopf LA, Gubareva L, Kniss K, Kramer N, O'Halloran A, Sessions W, Taylor C, Wentworth DE, Xu X, Fry AM, Katz J, Jernigan D.

MMWR Morb Mortal Wkly Rep. 2018 Dec 14;67(49):1369-1371. doi: 10.15585/mmwr.mm6749a4.

42.

Immunogenicity and Viral Shedding of Russian-Backbone, Seasonal, Trivalent, Live, Attenuated Influenza Vaccine in a Phase II, Randomized, Placebo-Controlled Trial Among Preschool-Aged Children in Urban Bangladesh.

Lewis KDC, Ortiz JR, Rahman MZ, Levine MZ, Rudenko L, Wright PF, Katz JM, Dally L, Rahman M, Isakova-Sivak I, Ilyushina NA, Matyushenko V, Fry AM, Lindstrom SE, Bresee JS, Brooks WA, Neuzil KM.

Clin Infect Dis. 2019 Aug 16;69(5):777-785. doi: 10.1093/cid/ciy1003.

43.

Influenza vaccine effectiveness among patients with high-risk medical conditions in the United States, 2012-2016.

Shang M, Chung JR, Jackson ML, Jackson LA, Monto AS, Martin ET, Belongia EA, McLean HQ, Gaglani M, Murthy K, Zimmerman RK, Nowalk MP, Fry AM, Flannery B.

Vaccine. 2018 Dec 18;36(52):8047-8053. doi: 10.1016/j.vaccine.2018.10.093. Epub 2018 Nov 9.

44.

Hospitalization following outpatient medical care for influenza: US influenza vaccine effectiveness network, 2011-12-2015-16.

Appiah GD, Chung JR, Flannery B, Havers FP, Zimmerman RK, Nowalk MP, Monto AS, Martin ET, Gaglani M, Murthy K, Jackson LA, Jackson ML, McLean HQ, Belongia EA, Fry AM.

Influenza Other Respir Viruses. 2019 Mar;13(2):133-137. doi: 10.1111/irv.12616. Epub 2018 Dec 19.

45.

Detection of Avian Influenza A(H7N2) Virus Infection Among Animal Shelter Workers Using a Novel Serological Approach-New York City, 2016-2017.

Poirot E, Levine MZ, Russell K, Stewart RJ, Pompey JM, Chiu S, Fry AM, Gross L, Havers FP, Li ZN, Liu F, Crossa A, Lee CT, Boshuizen V, Rakeman JL, Slavinski S, Harper S, Gould LH.

J Infect Dis. 2019 May 5;219(11):1688-1696. doi: 10.1093/infdis/jiy595.

PMID:
30395249
46.

Influenza Vaccine Effectiveness and Statin Use Among Adults in the United States, 2011-2017.

Havers FP, Chung JR, Belongia EA, McLean HQ, Gaglani M, Murthy K, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Monto AS, Petrie JG, Fry AM, Flannery B.

Clin Infect Dis. 2019 May 2;68(10):1616-1622. doi: 10.1093/cid/ciy780.

47.

Update: Influenza Activity - United States and Worldwide, May 20-October 13, 2018.

Chow EJ, Davis CT, Abd Elal AI, Alabi N, Azziz-Baumgartner E, Barnes J, Blanton L, Brammer L, Budd AP, Burns E, Davis WW, Dugan VG, Fry AM, Garten R, Grohskopf LA, Gubareva L, Jang Y, Jones J, Kniss K, Lindstrom S, Mustaquim D, Porter R, Rolfes M, Sessions W, Taylor C, Wentworth DE, Xu X, Zanders N, Katz J, Jernigan D.

MMWR Morb Mortal Wkly Rep. 2018 Oct 26;67(42):1178-1185. doi: 10.15585/mmwr.mm6742a3.

48.

Influenza Vaccine Effectiveness in the United States During the 2016-2017 Season.

Flannery B, Chung JR, Monto AS, Martin ET, Belongia EA, McLean HQ, Gaglani M, Murthy K, Zimmerman RK, Nowalk MP, Jackson ML, Jackson LA, Rolfes MA, Spencer S, Fry AM; US Flu VE Investigators.

Clin Infect Dis. 2019 May 17;68(11):1798-1806. doi: 10.1093/cid/ciy775.

49.

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices-United States, 2018-19 Influenza Season.

Grohskopf LA, Sokolow LZ, Broder KR, Walter EB, Fry AM, Jernigan DB.

MMWR Recomm Rep. 2018 Aug 24;67(3):1-20. doi: 10.15585/mmwr.rr6703a1.

50.

Author Correction: Plasmodium APC3 mediates chromosome condensation and cytokinesis during atypical mitosis in male gametogenesis.

Wall RJ, Ferguson DJP, Freville A, Franke-Fayard B, Brady D, Zeeshan M, Bottrill AR, Wheatley S, Fry AM, Janse CJ, Yamano H, Holder AA, Guttery DS, Tewari R.

Sci Rep. 2018 Aug 21;8(1):12814. doi: 10.1038/s41598-018-30924-6.

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