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Items: 1 to 50 of 93

1.

Serotonin Prevents Differentiation of Brown Adipocytes by Interfering with Their Clock.

Rozenblit-Susan S, Chapnik N, Froy O.

Obesity (Silver Spring). 2019 Nov 1. doi: 10.1002/oby.22606. [Epub ahead of print]

PMID:
31674727
2.

Reduction in Glycated Hemoglobin and Daily Insulin Dose Alongside Circadian Clock Upregulation in Patients With Type 2 Diabetes Consuming a Three-Meal Diet: A Randomized Clinical Trial.

Jakubowicz D, Landau Z, Tsameret S, Wainstein J, Raz I, Ahren B, Chapnik N, Barnea M, Ganz T, Menaged M, Mor N, Bar-Dayan Y, Froy O.

Diabetes Care. 2019 Sep 23. pii: dc191142. doi: 10.2337/dc19-1142. [Epub ahead of print]

PMID:
31548244
3.

Clock Gene Disruption is an Initial Manifestation of Inflammatory Bowel Disease.

Weintraub Y, Cohen S, Chapnik N, Ben-Tov A, Yerushalmy-Feler A, Dotan I, Tauman R, Froy O.

Clin Gastroenterol Hepatol. 2019 Apr 10. pii: S1542-3565(19)30373-8. doi: 10.1016/j.cgh.2019.04.013. [Epub ahead of print]

PMID:
30981000
4.

Non-obesogenic doses of fatty acids modulate the functionality of the circadian clock in the liver.

Tal Y, Chapnik N, Froy O.

Cell Mol Life Sci. 2019 May;76(9):1795-1806. doi: 10.1007/s00018-019-03023-6. Epub 2019 Jan 29.

PMID:
30694347
5.

The Circadian Clock Drives Mast Cell Functions in Allergic Reactions.

Christ P, Sowa AS, Froy O, Lorentz A.

Front Immunol. 2018 Jul 6;9:1526. doi: 10.3389/fimmu.2018.01526. eCollection 2018. Review.

6.

The Circadian Clock in White and Brown Adipose Tissue: Mechanistic, Endocrine, and Clinical Aspects.

Froy O, Garaulet M.

Endocr Rev. 2018 Jun 1;39(3):261-273. doi: 10.1210/er.2017-00193. Review.

7.

Serotonin prevents differentiation into brown adipocytes and induces transdifferentiation into white adipocytes.

Rozenblit-Susan S, Chapnik N, Froy O.

Int J Obes (Lond). 2018 Apr;42(4):704-710. doi: 10.1038/ijo.2017.261. Epub 2017 Oct 30.

PMID:
29081505
8.

Circadian rhythms, nutrition and implications for longevity in urban environments.

Froy O.

Proc Nutr Soc. 2018 Aug;77(3):216-222. doi: 10.1017/S0029665117003962. Epub 2017 Oct 25. Review.

PMID:
29065948
9.

High-energy breakfast based on whey protein reduces body weight, postprandial glycemia and HbA1C in Type 2 diabetes.

Jakubowicz D, Wainstein J, Landau Z, Ahren B, Barnea M, Bar-Dayan Y, Froy O.

J Nutr Biochem. 2017 Nov;49:1-7. doi: 10.1016/j.jnutbio.2017.07.005. Epub 2017 Jul 21.

PMID:
28863364
10.

Influences of Breakfast on Clock Gene Expression and Postprandial Glycemia in Healthy Individuals and Individuals With Diabetes: A Randomized Clinical Trial.

Jakubowicz D, Wainstein J, Landau Z, Raz I, Ahren B, Chapnik N, Ganz T, Menaged M, Barnea M, Bar-Dayan Y, Froy O.

Diabetes Care. 2017 Nov;40(11):1573-1579. doi: 10.2337/dc16-2753. Epub 2017 Aug 22.

PMID:
28830875
11.

Effect of brain-derived neurotrophic factor (BDNF) on hepatocyte metabolism.

Genzer Y, Chapnik N, Froy O.

Int J Biochem Cell Biol. 2017 Jul;88:69-74. doi: 10.1016/j.biocel.2017.05.008. Epub 2017 May 5.

PMID:
28483667
12.

Relationship between FGF21 and UCP1 levels under time-restricted feeding and high-fat diet.

Chapnik N, Genzer Y, Froy O.

J Nutr Biochem. 2017 Feb;40:116-121. doi: 10.1016/j.jnutbio.2016.10.017. Epub 2016 Nov 2.

PMID:
27883936
13.

Differential effect of fructose on fat metabolism and clock gene expression in hepatocytes vs. myotubes.

Chapnik N, Rozenblit-Susan S, Genzer Y, Froy O.

Int J Biochem Cell Biol. 2016 Aug;77(Pt A):35-40. doi: 10.1016/j.biocel.2016.05.019. Epub 2016 May 27.

PMID:
27240446
14.

Effect of dietary fat and the circadian clock on the expression of brain-derived neurotrophic factor (BDNF).

Genzer Y, Dadon M, Burg C, Chapnik N, Froy O.

Mol Cell Endocrinol. 2016 Jul 15;430:49-55. doi: 10.1016/j.mce.2016.04.015. Epub 2016 Apr 22.

PMID:
27113028
15.

Metabolic effect of fluvoxamine in mouse peripheral tissues.

Rozenblit-Susan S, Chapnik N, Froy O.

Mol Cell Endocrinol. 2016 Mar 15;424:12-22. doi: 10.1016/j.mce.2016.01.009. Epub 2016 Jan 12.

PMID:
26797245
16.

Serotonin suppresses food anticipatory activity and synchronizes the food-entrainable oscillator during time-restricted feeding.

Rozenblit-Susan S, Chapnik N, Genzer Y, Froy O.

Behav Brain Res. 2016 Jan 15;297:150-4. doi: 10.1016/j.bbr.2015.10.019. Epub 2015 Oct 20.

PMID:
26467604
17.

Ketogenic diet delays the phase of circadian rhythms and does not affect AMP-activated protein kinase (AMPK) in mouse liver.

Genzer Y, Dadon M, Burg C, Chapnik N, Froy O.

Mol Cell Endocrinol. 2015 Dec 5;417:124-30. doi: 10.1016/j.mce.2015.09.012. Epub 2015 Sep 25.

PMID:
26408964
18.

Fasting until noon triggers increased postprandial hyperglycemia and impaired insulin response after lunch and dinner in individuals with type 2 diabetes: a randomized clinical trial.

Jakubowicz D, Wainstein J, Ahren B, Landau Z, Bar-Dayan Y, Froy O.

Diabetes Care. 2015 Oct;38(10):1820-6. doi: 10.2337/dc15-0761. Epub 2015 Jul 28.

PMID:
26220945
19.

Concentrating carbohydrates before sleep improves feeding regulation and metabolic and inflammatory parameters in mice.

Sofer S, Eliraz A, Madar Z, Froy O.

Mol Cell Endocrinol. 2015 Oct 15;414:29-41. doi: 10.1016/j.mce.2015.06.032. Epub 2015 Jul 20.

PMID:
26206716
20.

High-energy breakfast with low-energy dinner decreases overall daily hyperglycaemia in type 2 diabetic patients: a randomised clinical trial.

Jakubowicz D, Wainstein J, Ahrén B, Bar-Dayan Y, Landau Z, Rabinovitz HR, Froy O.

Diabetologia. 2015 May;58(5):912-9. doi: 10.1007/s00125-015-3524-9. Epub 2015 Mar 1.

PMID:
25724569
21.

IgE-dependent activation of human mast cells and fMLP-mediated activation of human eosinophils is controlled by the circadian clock.

Baumann A, Feilhauer K, Bischoff SC, Froy O, Lorentz A.

Mol Immunol. 2015 Mar;64(1):76-81. doi: 10.1016/j.molimm.2014.10.026. Epub 2014 Nov 15.

PMID:
25466613
22.

The circadian clock machinery controls adiponectin expression.

Barnea M, Chapnik N, Genzer Y, Froy O.

Mol Cell Endocrinol. 2015 Jan 5;399:284-7. doi: 10.1016/j.mce.2014.10.018. Epub 2014 Oct 24.

PMID:
25448847
23.

Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial.

Jakubowicz D, Froy O, Ahrén B, Boaz M, Landau Z, Bar-Dayan Y, Ganz T, Barnea M, Wainstein J.

Diabetologia. 2014 Sep;57(9):1807-11. doi: 10.1007/s00125-014-3305-x. Epub 2014 Jul 10.

PMID:
25005331
24.

Effect of metformin and lipid emulsion on the circadian gene expression in muscle cells.

Barnea M, Cohen-Yogev T, Chapnik N, Madar Z, Froy O.

Int J Biochem Cell Biol. 2014 Aug;53:151-61. doi: 10.1016/j.biocel.2014.05.014. Epub 2014 May 17.

PMID:
24842104
25.

Long-term commercial cow's milk consumption and its effects on metabolic parameters associated with obesity in young mice.

Bar Yamin H, Barnea M, Genzer Y, Chapnik N, Froy O.

Mol Nutr Food Res. 2014 May;58(5):1061-8. doi: 10.1002/mnfr.201300650. Epub 2013 Dec 23.

PMID:
24550222
26.

AMPK-derived peptides reduce blood glucose levels but lead to fat retention in the liver of obese mice.

Chapnik N, Genzer Y, Ben-Shimon A, Niv MY, Froy O.

J Endocrinol. 2014 Mar 7;221(1):89-99. doi: 10.1530/JOE-13-0625. Print 2014 Apr.

PMID:
24478381
27.

Circadian aspects of energy metabolism and aging.

Froy O.

Ageing Res Rev. 2013 Sep;12(4):931-40. doi: 10.1016/j.arr.2013.09.002. Epub 2013 Sep 25. Review.

PMID:
24075855
28.

The circadian clock is functional in eosinophils and mast cells.

Baumann A, Gönnenwein S, Bischoff SC, Sherman H, Chapnik N, Froy O, Lorentz A.

Immunology. 2013 Dec;140(4):465-74. doi: 10.1111/imm.12157.

29.

Dexamethasone induces high-amplitude rhythms in preadipocytes, but hinders circadian expression in differentiated adipocytes.

Barnea M, Madar Z, Froy O.

Chronobiol Int. 2013 Jul;30(6):837-42. doi: 10.3109/07420528.2013.767824. Epub 2013 Jun 5.

PMID:
23738907
30.

Effects of caloric intake timing on insulin resistance and hyperandrogenism in lean women with polycystic ovary syndrome.

Jakubowicz D, Barnea M, Wainstein J, Froy O.

Clin Sci (Lond). 2013 Nov;125(9):423-32. doi: 10.1042/CS20130071.

PMID:
23688334
31.

A CRY for help to fight fat.

Froy O.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1129-30. doi: 10.1152/ajpendo.00233.2013. Epub 2013 Apr 30. No abstract available.

32.

High caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women.

Jakubowicz D, Barnea M, Wainstein J, Froy O.

Obesity (Silver Spring). 2013 Dec;21(12):2504-12. doi: 10.1002/oby.20460. Epub 2013 Jul 2.

33.

A superactive leptin antagonist alters metabolism and locomotion in high-leptin mice.

Chapnik N, Solomon G, Genzer Y, Miskin R, Gertler A, Froy O.

J Endocrinol. 2013 Apr 29;217(3):283-90. doi: 10.1530/JOE-13-0033. Print 2013 Jun.

PMID:
23482705
34.

Association between phase shifts, expression levels, and amplitudes in peripheral circadian clocks.

Barnea M, Sherman H, Genzer Y, Froy O.

Chronobiol Int. 2013 May;30(4):618-27. doi: 10.3109/07420528.2012.754456. Epub 2013 Feb 27.

PMID:
23445509
35.

Biochemical and metabolic mechanisms by which dietary whey protein may combat obesity and Type 2 diabetes.

Jakubowicz D, Froy O.

J Nutr Biochem. 2013 Jan;24(1):1-5. doi: 10.1016/j.jnutbio.2012.07.008. Epub 2012 Sep 17. Review.

PMID:
22995389
36.

Metformin affects the circadian clock and metabolic rhythms in a tissue-specific manner.

Barnea M, Haviv L, Gutman R, Chapnik N, Madar Z, Froy O.

Biochim Biophys Acta. 2012 Nov;1822(11):1796-806. doi: 10.1016/j.bbadis.2012.08.005. Epub 2012 Aug 16. Erratum in: Biochim Biophys Acta. 2013 May;1832(5):696.

37.

Timed high-fat diet resets circadian metabolism and prevents obesity.

Sherman H, Genzer Y, Cohen R, Chapnik N, Madar Z, Froy O.

FASEB J. 2012 Aug;26(8):3493-502. doi: 10.1096/fj.12-208868. Epub 2012 May 16.

PMID:
22593546
38.

Expression and structure/function relationships of human defensin 5.

Chapnik N, Levit A, Niv MY, Froy O.

Appl Biochem Biotechnol. 2012 Apr;166(7):1703-10. doi: 10.1007/s12010-012-9571-5. Epub 2012 Feb 22.

PMID:
22354633
39.

Circadian rhythms and obesity in mammals.

Froy O.

ISRN Obes. 2012 Nov 18;2012:437198. doi: 10.5402/2012/437198. eCollection 2012. Review.

40.

Meal timing and composition influence ghrelin levels, appetite scores and weight loss maintenance in overweight and obese adults.

Jakubowicz D, Froy O, Wainstein J, Boaz M.

Steroids. 2012 Mar 10;77(4):323-31. doi: 10.1016/j.steroids.2011.12.006. Epub 2011 Dec 9. Erratum in: Steroids. 2012 Jul;77(8-9):887-9.

PMID:
22178258
41.

Peroxisome proliferator-activated receptor α (PPARα) activation advances locomotor activity and feeding daily rhythms in mice.

Gutman R, Barnea M, Haviv L, Chapnik N, Froy O.

Int J Obes (Lond). 2012 Aug;36(8):1131-4. doi: 10.1038/ijo.2011.215. Epub 2011 Nov 8.

PMID:
22064158
42.

Circadian rhythms, aging, and life span in mammals.

Froy O.

Physiology (Bethesda). 2011 Aug;26(4):225-35. doi: 10.1152/physiol.00012.2011. Review.

43.

All-trans retinoic acid modifies the expression of clock and disease marker genes.

Sherman H, Gutman R, Chapnik N, Meylan J, le Coutre J, Froy O.

J Nutr Biochem. 2012 Mar;23(3):209-17. doi: 10.1016/j.jnutbio.2010.11.017. Epub 2011 Apr 15.

PMID:
21497500
44.

Long-lived mice exhibit 24 h locomotor circadian rhythms at young and old age.

Gutman R, Genzer Y, Chapnik N, Miskin R, Froy O.

Exp Gerontol. 2011 Jul;46(7):606-9. doi: 10.1016/j.exger.2011.02.015. Epub 2011 Mar 3.

PMID:
21376793
45.

Caffeine alters circadian rhythms and expression of disease and metabolic markers.

Sherman H, Gutman R, Chapnik N, Meylan J, le Coutre J, Froy O.

Int J Biochem Cell Biol. 2011 May;43(5):829-38. doi: 10.1016/j.biocel.2011.02.008. Epub 2011 Feb 23.

PMID:
21352949
46.

The circadian clock and metabolism.

Froy O.

Clin Sci (Lond). 2011 Jan;120(2):65-72. doi: 10.1042/CS20100327. Review.

PMID:
20929440
47.

Long-term restricted feeding alters circadian expression and reduces the level of inflammatory and disease markers.

Sherman H, Frumin I, Gutman R, Chapnik N, Lorentz A, Meylan J, le Coutre J, Froy O.

J Cell Mol Med. 2011 Dec;15(12):2745-59. doi: 10.1111/j.1582-4934.2010.01160.x.

48.

Spontaneous caloric restriction associated with increased leptin levels in obesity-resistant αMUPA mice.

Froy O, Sherman H, Bhargava G, Chapnik N, Cohen R, Gutman R, Kronfeld-Schor N, Miskin R.

Int J Obes (Lond). 2011 Feb;35(2):226-35. doi: 10.1038/ijo.2010.125. Epub 2010 Jun 15.

PMID:
20548306
49.

Defensin carriers for better mucosal immunity in the digestive system.

Froy O, Chapnik N, Nussinovitch A.

Int J Pharm. 2010 Jun 30;393(1-2):263-7. doi: 10.1016/j.ijpharm.2010.04.038. Epub 2010 May 8.

PMID:
20438821
50.

Effect of feeding regimens on circadian rhythms: implications for aging and longevity.

Froy O, Miskin R.

Aging (Albany NY). 2010 Dec 11;2(1):7-27. Review.

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