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Items: 1 to 50 of 58

1.

Selective inhibition of carbonic anhydrase IX over carbonic anhydrase XII in breast cancer cells using benzene sulfonamides: Disconnect between activity and growth inhibition.

Mboge MY, Chen Z, Wolff A, Mathias JV, Tu C, Brown KD, Bozdag M, Carta F, Supuran CT, McKenna R, Frost SC.

PLoS One. 2018 Nov 19;13(11):e0207417. doi: 10.1371/journal.pone.0207417. eCollection 2018.

2.

Biophysical, Biochemical, and Cell Based Approaches Used to Decipher the Role of Carbonic Anhydrases in Cancer and to Evaluate the Potency of Targeted Inhibitors.

Mboge MY, Kota A, McKenna R, Frost SC.

Int J Med Chem. 2018 Jul 16;2018:2906519. doi: 10.1155/2018/2906519. eCollection 2018. Review.

3.

Differential expression and function of CAIX and CAXII in breast cancer: A comparison between tumorgraft models and cells.

Chen Z, Ai L, Mboge MY, Tu C, McKenna R, Brown KD, Heldermon CD, Frost SC.

PLoS One. 2018 Jul 2;13(7):e0199476. doi: 10.1371/journal.pone.0199476. eCollection 2018.

4.

Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site.

Singh S, Lomelino CL, Mboge MY, Frost SC, McKenna R.

Molecules. 2018 Apr 30;23(5). pii: E1045. doi: 10.3390/molecules23051045. Review.

5.

UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system.

Chen Z, Ai L, Mboge MY, McKenna R, Frost CJ, Heldermon CD, Frost SC.

Cancer Biol Ther. 2018 Jul 3;19(7):598-608. doi: 10.1080/15384047.2018.1449612. Epub 2018 Apr 13.

PMID:
29561695
6.

Carbonic Anhydrases: Role in pH Control and Cancer.

Mboge MY, Mahon BP, McKenna R, Frost SC.

Metabolites. 2018 Feb 28;8(1). pii: E19. doi: 10.3390/metabo8010019. Review.

7.

Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides.

Mboge MY, Mahon BP, Lamas N, Socorro L, Carta F, Supuran CT, Frost SC, McKenna R.

Eur J Med Chem. 2017 May 26;132:184-191. doi: 10.1016/j.ejmech.2017.03.026. Epub 2017 Mar 19.

8.

The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis.

Mahon BP, Bhatt A, Socorro L, Driscoll JM, Okoh C, Lomelino CL, Mboge MY, Kurian JJ, Tu C, Agbandje-McKenna M, Frost SC, McKenna R.

Biochemistry. 2016 Aug 23;55(33):4642-53. doi: 10.1021/acs.biochem.6b00243. Epub 2016 Aug 5.

9.

Effects of acid-base variables and the role of carbonic anhydrase on oxalate secretion by the mouse intestine in vitro.

Whittamore JM, Frost SC, Hatch M.

Physiol Rep. 2015 Feb 25;3(2). pii: e12282. doi: 10.14814/phy2.12282. Print 2015 Feb 1.

10.

Advances in Anti-Cancer Drug Development Targeting Carbonic Anhydrase IX and XII.

Mboge MY, McKenna R, Frost SC.

Top Anticancer Res. 2015;5:3-42.

11.

Physiological functions of the alpha class of carbonic anhydrases.

Frost SC.

Subcell Biochem. 2014;75:9-30. doi: 10.1007/978-94-007-7359-2_2. Review.

PMID:
24146372
12.

Overview of the carbonic anhydrase family.

McKenna R, Frost SC.

Subcell Biochem. 2014;75:3-5. doi: 10.1007/978-94-007-7359-2_1.

PMID:
24146371
13.

Role of zinc in catalytic activity of carbonic anhydrase IX.

Tu C, Foster L, Alvarado A, McKenna R, Silverman DN, Frost SC.

Arch Biochem Biophys. 2012 May;521(1-2):90-4. doi: 10.1016/j.abb.2012.03.017. Epub 2012 Mar 23.

14.

Catalysis and pH control by membrane-associated carbonic anhydrase IX in MDA-MB-231 breast cancer cells.

Li Y, Tu C, Wang H, Silverman DN, Frost SC.

J Biol Chem. 2011 May 6;286(18):15789-96. doi: 10.1074/jbc.M110.188524. Epub 2011 Mar 17.

15.

The promise of nanotechnology for solving clinical problems in breast cancer.

Grobmyer SR, Morse DL, Fletcher B, Gutwein LG, Sharma P, Krishna V, Frost SC, Moudgil BM, Brown SC.

J Surg Oncol. 2011 Mar 15;103(4):317-25. doi: 10.1002/jso.21698. Review.

PMID:
21337565
16.

Role of hypoxia and EGF on expression, activity, localization and phosphorylation of carbonic anhydrase IX in MDA-MB-231 breast cancer cells.

Li Y, Wang H, Tu C, Shiverick KT, Silverman DN, Frost SC.

Biochim Biophys Acta. 2011 Jan;1813(1):159-67. doi: 10.1016/j.bbamcr.2010.09.018. Epub 2010 Oct 12.

17.

Detecting extracellular carbonic anhydrase activity using membrane inlet mass spectrometry.

Delacruz J, Mikulski R, Tu C, Li Y, Wang H, Shiverick KT, Frost SC, Horenstein NA, Silverman DN.

Anal Biochem. 2010 Aug;403(1-2):74-8. doi: 10.1016/j.ab.2010.04.019. Epub 2010 Apr 22.

18.

Antibody-specific detection of CAIX in breast and prostate cancers.

Li Y, Wang H, Oosterwijk E, Selman Y, Mira JC, Medrano T, Shiverick KT, Frost SC.

Biochem Biophys Res Commun. 2009 Aug 28;386(3):488-92. doi: 10.1016/j.bbrc.2009.06.064. Epub 2009 Jun 16.

19.

Expression and activity of carbonic anhydrase IX is associated with metabolic dysfunction in MDA-MB-231 breast cancer cells.

Li Y, Wang H, Oosterwijk E, Tu C, Shiverick KT, Silverman DN, Frost SC.

Cancer Invest. 2009 Jul;27(6):613-23. doi: 10.1080/07357900802653464.

20.

Berberine activates GLUT1-mediated glucose uptake in 3T3-L1 adipocytes.

Kim SH, Shin EJ, Kim ED, Bayaraa T, Frost SC, Hyun CK.

Biol Pharm Bull. 2007 Nov;30(11):2120-5.

21.

Angiogenic factors for the prediction of preeclampsia in high-risk women.

Moore Simas TA, Crawford SL, Solitro MJ, Frost SC, Meyer BA, Maynard SE.

Am J Obstet Gynecol. 2007 Sep;197(3):244.e1-8.

PMID:
17826405
22.

Soluble fibroin enhances insulin sensitivity and glucose metabolism in 3T3-L1 adipocytes.

Hyun CK, Kim IY, Frost SC.

J Nutr. 2004 Dec;134(12):3257-63.

PMID:
15570022
23.

Glucose deprivation enhances targeting of GLUT1 to lipid rafts in 3T3-L1 adipocytes.

Kumar A, Xiao YP, Laipis PJ, Fletcher BS, Frost SC.

Am J Physiol Endocrinol Metab. 2004 Apr;286(4):E568-76. Epub 2003 Dec 9.

24.

Glycogen phosphorylase is activated in response to glucose deprivation but is not responsible for enhanced glucose transport activity in 3T3-L1 adipocytes.

McInerney M, Serrano Rodriguez G, Pawlina W, Hurt CB, Fletcher BS, Laipis PJ, Frost SC.

Biochim Biophys Acta. 2002 Feb 15;1570(1):53-62.

PMID:
11960689
25.
26.

Glucose deprivation does not affect GLUT1 targeting in 3T3-L1 adipocytes.

McMahon RJ, Hwang JB, Frost SC.

Biochem Biophys Res Commun. 2000 Jul 14;273(3):859-64.

PMID:
10891337
27.

Effect of alternative glycosylation on insulin receptor processing.

Hwang JB, Frost SC.

J Biol Chem. 1999 Aug 6;274(32):22813-20.

28.

Is stress radiography necessary in the diagnosis of acute or chronic ankle instability?

Frost SC, Amendola A.

Clin J Sport Med. 1999 Jan;9(1):40-5. Review.

PMID:
10336051
29.

Using magnetic beads to isolate inside-out GLUT1-containing vesicles from 3T3-L1 adipocyte plasma membranes.

Fisher MD, Frost SC.

Anal Biochem. 1997 Aug 15;251(1):125-6. No abstract available.

PMID:
9300096
30.

Development of insulin resistance in 3T3-L1 adipocytes.

Thomson MJ, Williams MG, Frost SC.

J Biol Chem. 1997 Mar 21;272(12):7759-64.

31.

Insulin-stimulated glucose disposal: does adipose play a role?

Frost SC.

Nutr Rev. 1996 Oct;54(10):329-31. Review.

PMID:
9063024
32.

Differential regulation of GRP78 and GLUT1 expression in 3T3-L1 adipocytes.

Kitzman HH Jr, McMahon RJ, Aslanian AM, Fadia PM, Frost SC.

Mol Cell Biochem. 1996 Sep 6;162(1):51-8.

PMID:
8905625
33.
34.
35.

Nutrient control of GLUT1 processing and turnover in 3T3-L1 adipocytes.

McMahon RJ, Frost SC.

J Biol Chem. 1995 May 19;270(20):12094-9.

36.

Effect of glucose deprivation of GLUT 1 expression in 3T3-L1 adipocytes.

Kitzman HH Jr, McMahon RJ, Williams MG, Frost SC.

J Biol Chem. 1993 Jan 15;268(2):1320-5.

37.

Retinoic acid effects on cell death and division patterns in experimental chick wing buds.

Frost SC, Hinchliffe JR.

Prog Clin Biol Res. 1993;383B:769-79. No abstract available.

PMID:
8115392
38.

Regulation of annexin I in adipogenesis: cAMP-independent action of methylisobutylxanthine.

Wong WT, Nick HS, Frost SC.

Am J Physiol. 1992 Jan;262(1 Pt 1):C91-7.

PMID:
1370745
39.

Protein-synthesis-dependent induction of annexin I by glucocorticoid.

Wong WT, Frost SC, Nick HS.

Biochem J. 1991 Apr 15;275 ( Pt 2):313-9.

40.

Annexin-I regulation in response to suckling and rat mammary cell differentiation.

Horlick KR, Ganjianpour M, Frost SC, Nick HS.

Endocrinology. 1991 Mar;128(3):1574-9.

PMID:
1825630
41.

Role of receptor internalization in insulin signalling.

Frost SC, Risch R.

Adv Exp Med Biol. 1991;293:215-25. Review. No abstract available.

PMID:
1767732
42.

Uptake and binding of radiolabelled phenylarsine oxide in 3T3-L1 adipocytes.

Frost SC, Schwalbe MS.

Biochem J. 1990 Aug 1;269(3):589-95.

43.

Human relaxin inhibits division but not differentiation of 3T3-L1 cells.

Pawlina W, Larkin LH, Ogilvie S, Frost SC.

Mol Cell Endocrinol. 1990 Jul 30;72(1):55-61.

PMID:
2272403
44.
45.

Effect of relaxin on differentiation of 3T3-L1 preadipocytes.

Pawlina W, Larkin LH, Frost SC.

Endocrinology. 1989 Oct;125(4):2049-55.

PMID:
2676478
46.

Effect of phenylarsine oxide on protein synthesis in 3T3-L1 adipocytes.

Pettengell K, Frost SC.

Biochem Biophys Res Commun. 1989 Jun 15;161(2):633-9.

PMID:
2735914
47.
48.
49.

Insulin stimulates fluid-phase endocytosis and exocytosis in 3T3-L1 adipocytes.

Gibbs EM, Lienhard GE, Appleman JR, Lane MD, Frost SC.

J Biol Chem. 1986 Mar 25;261(9):3944-51.

50.

Identification and partial purification of the insulin-responsive glucose transporter from 3T3-L1 adipocytes.

Schroer DW, Frost SC, Kohanski RA, Lane MD, Lienhard GE.

Biochim Biophys Acta. 1986 Mar 14;885(3):317-26.

PMID:
3511974

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