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Items: 35

1.

KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions.

Marella M, Jadin L, Keller GA, Sugarman BJ, Frost GI, Shepard HM.

Glycobiology. 2018 Dec 1;28(12):958-967. doi: 10.1093/glycob/cwy064.

2.

PH20 is not expressed in murine CNS and oligodendrocyte precursor cells.

Marella M, Ouyang J, Zombeck J, Zhao C, Huang L, Connor RJ, Phan KB, Jorge MC, Printz MA, Paladini RD, Gelb AB, Huang Z, Frost GI, Sugarman BJ, Steinman L, Wei G, Shepard HM, Maneval DC, Lapinskas PJ.

Ann Clin Transl Neurol. 2017 Feb 23;4(3):191-211. doi: 10.1002/acn3.393. eCollection 2017 Mar.

3.

Interstitial Pressure in Pancreatic Ductal Adenocarcinoma Is Dominated by a Gel-Fluid Phase.

DuFort CC, DelGiorno KE, Carlson MA, Osgood RJ, Zhao C, Huang Z, Thompson CB, Connor RJ, Thanos CD, Scott Brockenbrough J, Provenzano PP, Frost GI, Michael Shepard H, Hingorani SR.

Biophys J. 2016 May 10;110(9):2106-19. doi: 10.1016/j.bpj.2016.03.040.

4.

Erratum to: Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration.

Rosengren S, Dychter SS, Printz MA, Huang L, Schiff RI, Schwarz HP, McVey JK, Drake FH, Maneval DC, Kennard DA, Frost GI, Sugarman BJ, Muchmore DB.

AAPS J. 2015 Nov;17(6):1523-4. doi: 10.1208/s12248-015-9822-9. No abstract available.

5.

Clinical Immunogenicity of rHuPH20, a Hyaluronidase Enabling Subcutaneous Drug Administration.

Rosengren S, Dychter SS, Printz MA, Huang L, Schiff RI, Schwarz HP, McVey JK, Drake FH, Maneval DC, Kennard DA, Frost GI, Sugarman BJ, Muchmore DB.

AAPS J. 2015 Sep;17(5):1144-56. doi: 10.1208/s12248-015-9782-0. Epub 2015 May 13. Erratum in: AAPS J. 2015 Nov;17(6):1523-4.

6.

Tumor-associated hyaluronan limits efficacy of monoclonal antibody therapy.

Singha NC, Nekoroski T, Zhao C, Symons R, Jiang P, Frost GI, Huang Z, Shepard HM.

Mol Cancer Ther. 2015 Feb;14(2):523-32. doi: 10.1158/1535-7163.MCT-14-0580. Epub 2014 Dec 15.

7.

Accumulation of extracellular hyaluronan by hyaluronan synthase 3 promotes tumor growth and modulates the pancreatic cancer microenvironment.

Kultti A, Zhao C, Singha NC, Zimmerman S, Osgood RJ, Symons R, Jiang P, Li X, Thompson CB, Infante JR, Jacobetz MA, Tuveson DA, Frost GI, Shepard HM, Huang Z.

Biomed Res Int. 2014;2014:817613. doi: 10.1155/2014/817613. Epub 2014 Jul 24.

8.

Response to Chauhan et Al.: interstitial pressure and vascular collapse in pancreas cancer-fluids and solids, measurement and meaning.

DelGiorno KE, Carlson MA, Osgood R, Provenzano PP, Brockenbough JS, Thompson CB, Shepard HM, Frost GI, Potter JD, Hingorani SR.

Cancer Cell. 2014 Jul 14;26(1):16-7. doi: 10.1016/j.ccr.2014.06.004. No abstract available.

9.

Characterization of a novel recombinant hyaluronan binding protein for tissue hyaluronan detection.

Jadin L, Huang L, Wei G, Zhao Q, Gelb AB, Frost GI, Jiang P, Shepard HM.

J Histochem Cytochem. 2014 Sep;62(9):672-83. doi: 10.1369/0022155414540176. Epub 2014 Jun 2.

PMID:
24891594
10.

Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation.

Huang Z, Zhao C, Chen Y, Cowell JA, Wei G, Kultti A, Huang L, Thompson CB, Rosengren S, Frost GI, Shepard HM.

J Immunol. 2014 Jun 1;192(11):5285-95. doi: 10.4049/jimmunol.1303060. Epub 2014 Apr 28.

11.

A recombinant human hyaluronidase sustained release gel for the treatment of post-surgical edema.

Nekoroski T, Paladini RD, Sauder DN, Frost GI, Keller GA.

Int J Dermatol. 2014 Jun;53(6):777-85. doi: 10.1111/ijd.12304. Epub 2013 Oct 29.

PMID:
24168080
12.

Mutations in the catalytic domain of human matrix metalloproteinase-1 (MMP-1) that allow for regulated activity through the use of Ca2+.

Paladini RD, Wei G, Kundu A, Zhao Q, Bookbinder LH, Keller GA, Shepard HM, Frost GI.

J Biol Chem. 2013 Mar 1;288(9):6629-39. doi: 10.1074/jbc.M112.364729. Epub 2013 Jan 15.

13.

Effective targeting of the tumor microenvironment for cancer therapy.

Jiang P, Li X, Thompson CB, Huang Z, Araiza F, Osgood R, Wei G, Feldmann M, Frost GI, Shepard HM.

Anticancer Res. 2012 Apr;32(4):1203-12.

PMID:
22493350
14.

Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer.

Jacobetz MA, Chan DS, Neesse A, Bapiro TE, Cook N, Frese KK, Feig C, Nakagawa T, Caldwell ME, Zecchini HI, Lolkema MP, Jiang P, Kultti A, Thompson CB, Maneval DC, Jodrell DI, Frost GI, Shepard HM, Skepper JN, Tuveson DA.

Gut. 2013 Jan;62(1):112-20. doi: 10.1136/gutjnl-2012-302529. Epub 2012 Mar 30.

15.

Therapeutic targeting of hyaluronan in the tumor stroma.

Kultti A, Li X, Jiang P, Thompson CB, Frost GI, Shepard HM.

Cancers (Basel). 2012 Sep 6;4(3):873-903. doi: 10.3390/cancers4030873.

16.

A comprehensive model of hyaluronan turnover in the mouse.

Jadin L, Bookbinder LH, Frost GI.

Matrix Biol. 2012 Mar;31(2):81-9. doi: 10.1016/j.matbio.2011.11.002. Epub 2011 Nov 26.

PMID:
22142621
17.

Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models.

Thompson CB, Shepard HM, O'Connor PM, Kadhim S, Jiang P, Osgood RJ, Bookbinder LH, Li X, Sugarman BJ, Connor RJ, Nadjsombati S, Frost GI.

Mol Cancer Ther. 2010 Nov;9(11):3052-64. doi: 10.1158/1535-7163.MCT-10-0470. Epub 2010 Oct 26.

18.

Accelerated pharmacokinetics and glucodynamics of prandial insulins injected with recombinant human hyaluronidase.

Vaughn DE, Yocum RC, Muchmore DB, Sugarman BJ, Vick AM, Bilinsky IP, Frost GI.

Diabetes Technol Ther. 2009 Jun;11(6):345-52. doi: 10.1089/dia.2009.0013.

PMID:
19459762
19.

Skeletal and hematological anomalies in HYAL2-deficient mice: a second type of mucopolysaccharidosis IX?

Jadin L, Wu X, Ding H, Frost GI, Onclinx C, Triggs-Raine B, Flamion B.

FASEB J. 2008 Dec;22(12):4316-26. doi: 10.1096/fj.08-111997. Epub 2008 Sep 4.

PMID:
18772348
20.
21.

A recombinant human enzyme for enhanced interstitial transport of therapeutics.

Bookbinder LH, Hofer A, Haller MF, Zepeda ML, Keller GA, Lim JE, Edgington TS, Shepard HM, Patton JS, Frost GI.

J Control Release. 2006 Aug 28;114(2):230-41. Epub 2006 Jun 7.

PMID:
16876899
22.

Novel syngeneic pseudo-orthotopic prostate cancer model: vascular, mitotic and apoptotic responses to castration.

Frost GI, Lustgarten J, Dudouet B, Nyberg L, Hartley-Asp B, Borgström P.

Microvasc Res. 2005 Jan;69(1-2):1-9.

PMID:
15797254
24.

Cooperative effect between immunotherapy and antiangiogenic therapy leads to effective tumor rejection in tolerant Her-2/neu mice.

Cuadros C, Dominguez AL, Frost GI, Borgstrom P, Lustgarten J.

Cancer Res. 2003 Sep 15;63(18):5895-901.

25.

Real time in vivo quantitation of tumor angiogenesis.

Frost GI, Borgström P.

Methods Mol Med. 2003;85:65-78. Review. No abstract available.

PMID:
12710198
26.

Hyaluronidase reduces human breast cancer xenografts in SCID mice.

Shuster S, Frost GI, Csoka AB, Formby B, Stern R.

Int J Cancer. 2002 Nov 10;102(2):192-7.

27.

The six hyaluronidase-like genes in the human and mouse genomes.

Csoka AB, Frost GI, Stern R.

Matrix Biol. 2001 Dec;20(8):499-508. Review.

PMID:
11731267
28.
29.
30.

A new disorder of hyaluronan metabolism associated with generalized folding and thickening of the skin.

Ramsden CA, Bankier A, Brown TJ, Cowen PS, Frost GI, McCallum DD, Studdert VP, Fraser JR.

J Pediatr. 2000 Jan;136(1):62-8.

PMID:
10636976
31.

The hyaluronidase gene HYAL1 maps to chromosome 3p21.2-p21.3 in human and 9F1-F2 in mouse, a conserved candidate tumor suppressor locus.

Csóka AB, Frost GI, Heng HH, Scherer SW, Mohapatra G, Stern R.

Genomics. 1998 Feb 15;48(1):63-70. Erratum in: Genomics. 2004 Jul;84(1):227.. Csóka, T B [corrected to Csóka, A B].

PMID:
9503017
32.

Purification and microsequencing of hyaluronidase isozymes from human urine.

Csóka AB, Frost GI, Wong T, Stern R.

FEBS Lett. 1997 Nov 17;417(3):307-10. Erratum in: FEBS Lett. 2004 May 21;566(1-3):316.. Csoka, T B [corrected to Csoka, A B].

33.

A microtiter-based assay for hyaluronidase activity not requiring specialized reagents.

Frost GI, Stern R.

Anal Biochem. 1997 Sep 5;251(2):263-9.

PMID:
9299025
34.

Purification, cloning, and expression of human plasma hyaluronidase.

Frost GI, Csóka AB, Wong T, Stern R.

Biochem Biophys Res Commun. 1997 Jul 9;236(1):10-5. Erratum in: Biochem Biophys Res Commun. 2004 Jun 25;319(2):705.. Csoka, T B [corrected to Csoka, A B].

PMID:
9223416
35.

Hyaluronidases in tissue invasion.

Csóka TB, Frost GI, Stern R.

Invasion Metastasis. 1997;17(6):297-311. Review.

PMID:
9949289

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