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Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease.

Weston PSJ, Poole T, O'Connor A, Heslegrave A, Ryan NS, Liang Y, Druyeh R, Mead S, Blennow K, Schott JM, Frost C, Zetterberg H, Fox NC.

Alzheimers Res Ther. 2019 Feb 20;11(1):19. doi: 10.1186/s13195-019-0472-5.


Findings of Impaired Hearing in Patients With Nonfluent/Agrammatic Variant Primary Progressive Aphasia.

Hardy CJD, Frost C, Sivasathiaseelan H, Johnson JCS, Agustus JL, Bond RL, Benhamou E, Russell LL, Marshall CR, Rohrer JD, Bamiou DE, Warren JD.

JAMA Neurol. 2019 Feb 11. doi: 10.1001/jamaneurol.2018.4799. [Epub ahead of print]


Is improvement in comorbid major depression associated with longer survival in people with cancer? A long-term follow-up of participants in the SMaRT Oncology-2 and 3 trials.

Mulick A, Walker J, Puntis S, Symeonides S, Gourley C, Burke K, Wanat M, Frost C, Sharpe M.

J Psychosom Res. 2019 Jan;116:106-112. doi: 10.1016/j.jpsychores.2018.11.008. Epub 2018 Nov 14.


Comparative detection method of early onset cytokine-induced stress in β-cells (INS-1E).

Beukes N, Levendal RA, Prinsloo E, Frost C.

Biotechnol Appl Biochem. 2019 Jan 15. doi: 10.1002/bab.1729. [Epub ahead of print]


Evaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects.

Frost C, Shenker A, Jhee S, Yu Z, Wang J, Bragat A, Pursley J, LaCreta F.

Clin Pharmacol. 2018 Oct 24;10:153-163. doi: 10.2147/CPAA.S169505. eCollection 2018.


Regenerative peripheral nerve interfaces for real-time, proportional control of a Neuroprosthetic hand.

Frost CM, Ursu DC, Flattery SM, Nedic A, Hassett CA, Moon JD, Buchanan PJ, Brent Gillespie R, Kung TA, Kemp SWP, Cederna PS, Urbanchek MG.

J Neuroeng Rehabil. 2018 Nov 20;15(1):108. doi: 10.1186/s12984-018-0452-1.


Collaborative Skills Essential to Leadership.

Van Hala S, Cochella S, Frost CJ, Gren L.

Fam Med. 2018 Oct;50(9):712-713. doi: 10.22454/FamMed.2018.743907. No abstract available.


Moderate levels of glyphosate and its formulations vary in their cytotoxicity and genotoxicity in a whole blood model and in human cell lines with different estrogen receptor status.

De Almeida LKS, Pletschke BI, Frost CL.

3 Biotech. 2018 Oct;8(10):438. doi: 10.1007/s13205-018-1464-z. Epub 2018 Oct 4.


Population Pharmacokinetics of Apixaban in Subjects With Nonvalvular Atrial Fibrillation.

Cirincione B, Kowalski K, Nielsen J, Roy A, Thanneer N, Byon W, Boyd R, Wang X, Leil T, LaCreta F, Ueno T, Oishi M, Frost C.

CPT Pharmacometrics Syst Pharmacol. 2018 Nov;7(11):728-738. doi: 10.1002/psp4.12347. Epub 2018 Sep 30.


Determining Physical and Mental Health Conditions Present in Older Adult Refugees: A Mini-Review.

Frost CJ, Morgan NJ, Allkhenfr H, Dearden S, Ess R, Albalawi WF, Berri A, Benson LS, Gren LH.

Gerontology. 2018 Aug 21:1-7. doi: 10.1159/000491695. [Epub ahead of print] Review.


Longitudinal Growth Outcomes Following First-line Treatment for Pediatric Patients With Eosinophilic Esophagitis.

Jensen ET, Huang KZ, Chen HX, Landes LE, McConnell KA, Almond MA, Safta AM, Johnston DT, Durban R, Jobe L, Frost C, Donnelly S, Antonio B, Quiros A, Markowitz JE, Dellon ES.

J Pediatr Gastroenterol Nutr. 2019 Jan;68(1):50-55. doi: 10.1097/MPG.0000000000002114.


Navigational cue effects in Alzheimer's disease and posterior cortical atrophy.

Yong KXX, McCarthy ID, Poole T, Suzuki T, Yang B, Carton AM, Holloway C, Papadosifos N, Boampong D, Langham J, Slattery CF, Paterson RW, Foulkes AJM, Schott JM, Frost C, Tyler N, Crutch SJ.

Ann Clin Transl Neurol. 2018 Apr 20;5(6):697-709. doi: 10.1002/acn3.566. eCollection 2018 Jun.


Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.

Barnes J, Bartlett JW, Wolk DA, van der Flier WM, Frost C.

J Alzheimers Dis. 2018;64(2):631-642. doi: 10.3233/JAD-170841.


Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements.

Spanopoulou A, Heidrich L, Chen HR, Frost C, Hrle D, Malideli E, Hille K, Grammatikopoulos A, Bernhagen J, Zacharias M, Rammes G, Kapurniotu A.

Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14503-14508. doi: 10.1002/anie.201802979. Epub 2018 Jul 24.


Practice Pattern Variation in Pediatric Eosinophilic Esophagitis in the Carolinas EoE Collaborative: A Research Model in Community and Academic Practices.

Huang KZ, Jensen ET, Chen HX, Landes LE, McConnell KA, Almond MA, Johnston DT, Durban R, Jobe L, Frost C, Donnelly S, Antonio B, Safta AM, Quiros JA, Markowitz JE, Dellon ES.

South Med J. 2018 Jun;111(6):328-332. doi: 10.14423/SMJ.0000000000000817.


Assessing patient readiness for personalized genomic medicine.

Frost CJ, Andrulis IL, Buys SS, Hopper JL, John EM, Terry MB, Bradbury A, Chung WK, Colbath K, Quintana N, Gamarra E, Egleston B, Galpern N, Bealin L, Glendon G, Miller LP, Daly MB.

J Community Genet. 2019 Jan;10(1):109-120. doi: 10.1007/s12687-018-0365-5. Epub 2018 May 26.


Publication Rate of Podium Presentations From the North American Spine Society Annual Meetings.

Raudenbush B, Frost C, Okafor R, Chen C, Qui X, Mesfin A.

Global Spine J. 2018 May;8(3):273-278. doi: 10.1177/2192568217713732. Epub 2017 Jun 23.


Childhood Emotional Abuse Moderates Associations Among Corticomotor White Matter Structure and Stress Neuromodulators in Women With and Without Depression.

Frost CP, Meyerand ME, Birn RM, Hoks RM, Walsh EC, Abercrombie HC.

Front Neurosci. 2018 Apr 23;12:256. doi: 10.3389/fnins.2018.00256. eCollection 2018.


A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study.

Ridha BH, Crutch S, Cutler D, Frost C, Knight W, Barker S, Epie N, Warrington EK, Kukkastenvehmas R, Douglas J, Rossor MN.

Alzheimers Res Ther. 2018 May 1;10(1):44. doi: 10.1186/s13195-018-0363-1.


Development and Validation of the Foundational Healthcare Leadership Self-assessment.

Van Hala S, Cochella S, Jaggi R, Frost CJ, Kiraly B, Pohl S, Gren L.

Fam Med. 2018 Apr;50(4):262-268. doi: 10.22454/FamMed.2018.835145.


Regional Gastrointestinal Absorption of Apixaban in Healthy Subjects.

Byon W, Nepal S, Schuster AE, Shenker A, Frost CE.

J Clin Pharmacol. 2018 Jul;58(7):965-971. doi: 10.1002/jcph.1097. Epub 2018 Mar 26.


The prevalence of depression in general hospital inpatients: a systematic review and meta-analysis of interview-based studies.

Walker J, Burke K, Wanat M, Fisher R, Fielding J, Mulick A, Puntis S, Sharpe J, Esposti MD, Harriss E, Frost C, Sharpe M.

Psychol Med. 2018 Oct;48(14):2285-2298. doi: 10.1017/S0033291718000624. Epub 2018 Mar 26.


UFH-001 cells: A novel triple negative, CAIX-positive, human breast cancer model system.

Chen Z, Ai L, Mboge MY, McKenna R, Frost CJ, Heldermon CD, Frost SC.

Cancer Biol Ther. 2018 Jul 3;19(7):598-608. doi: 10.1080/15384047.2018.1449612. Epub 2018 Apr 13.


Does depression treatment improve the survival of depressed patients with cancer? A long-term follow-up of participants in the SMaRT Oncology-2 and 3 trials.

Mulick A, Walker J, Puntis S, Burke K, Symeonides S, Gourley C, Wanat M, Frost C, Sharpe M.

Lancet Psychiatry. 2018 Apr;5(4):321-326. doi: 10.1016/S2215-0366(18)30061-0. Epub 2018 Mar 12.


Health and Well-being of Women Migrating from Predominantly Muslim Countries to the United States.

Kamimura A, Pye M, Sin K, Nourian MM, Assasnik N, Stoddard M, Frost CJ.

J Health Care Poor Underserved. 2018;29(1):337-348. doi: 10.1353/hpu.2018.0023.


Neural Signaling of Cortisol, Childhood Emotional Abuse, and Depression-Related Memory Bias.

Abercrombie HC, Frost CP, Walsh EC, Hoks RM, Cornejo MD, Sampe MC, Gaffey AE, Plante DT, Ladd CO, Birn RM.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Mar;3(3):274-284. doi: 10.1016/j.bpsc.2017.11.005. Epub 2017 Nov 22.


CSF neurogranin or tau distinguish typical and atypical Alzheimer disease.

Wellington H, Paterson RW, Suárez-González A, Poole T, Frost C, Sjöbom U, Slattery CF, Magdalinou NK, Lehmann M, Portelius E, Fox NC, Blennow K, Zetterberg H, Schott JM.

Ann Clin Transl Neurol. 2018 Jan 11;5(2):162-171. doi: 10.1002/acn3.518. eCollection 2018 Feb.


Time-dependent effect of phytocannabinoid treatments in fat cells.

Ramlugon S, Levendal RA, Frost CL.

Phytother Res. 2018 Jun;32(6):1080-1089. doi: 10.1002/ptr.6047. Epub 2018 Feb 21.


Improving the understanding of plasma kallikrein contribution to arterial thrombus formation using two plant protease inhibitors.

Salu BR, Pando SC, Brito MV, Medina AF, Odei-Addo F, Frost C, Naude R, Sampaio MU, Emsley J, Maffei FHA, Oliva MLV.

Platelets. 2018 Feb 14:1-9. doi: 10.1080/09537104.2018.1428738. [Epub ahead of print]


Neural and behavioral correlates of negative self-focused thought associated with depression.

Philippi CL, Cornejo MD, Frost CP, Walsh EC, Hoks RM, Birn R, Abercrombie HC.

Hum Brain Mapp. 2018 May;39(5):2246-2257. doi: 10.1002/hbm.24003. Epub 2018 Feb 9.


Management of Bilateral Edentulous Mandible Fractures Through an Intraoral Approach Using CAD/CAM Technology: A Case Report.

Wang HD, Frost C, Cusano A, Dorafshar AH.

J Oral Maxillofac Surg. 2018 May;76(5):1056.e1-1056.e6. doi: 10.1016/j.joms.2018.01.008. Epub 2018 Jan 31.


In Vitro Screening of Synthetic Fluorogenic Substrates for Detection of Cancer Procoagulant Activity.

Krause J, Frost CL.

Protein J. 2018 Apr;37(2):151-163. doi: 10.1007/s10930-018-9758-x.


Combining optical coherence tomography with visual field data to rapidly detect disease progression in glaucoma: a diagnostic accuracy study.

Garway-Heath DF, Zhu H, Cheng Q, Morgan K, Frost C, Crabb DP, Ho TA, Agiomyrgiannakis Y.

Health Technol Assess. 2018 Jan;22(4):1-106. doi: 10.3310/hta22040.


First-in-human study to assess the safety, pharmacokinetics and pharmacodynamics of BMS-962212, a direct, reversible, small molecule factor XIa inhibitor in non-Japanese and Japanese healthy subjects.

Perera V, Luettgen JM, Wang Z, Frost CE, Yones C, Russo C, Lee J, Zhao Y, LaCreta FP, Ma X, Knabb RM, Seiffert D, DeSouza M, Mugnier P, Cirincione B, Ueno T, Frost RJA.

Br J Clin Pharmacol. 2018 May;84(5):876-887. doi: 10.1111/bcp.13520. Epub 2018 Mar 5.


Comparing Diet and Exercise Monitoring Using Smartphone App and Paper Diary: A Two-Phase Intervention Study.

Jimoh F, Lund EK, Harvey LJ, Frost C, Lay WJ, Roe MA, Berry R, Finglas PM.

JMIR Mhealth Uhealth. 2018 Jan 15;6(1):e17. doi: 10.2196/mhealth.7702.


Safety and Efficacy of Reslizumab for Children and Adolescents With Eosinophilic Esophagitis Treated for 9 Years.

Markowitz JE, Jobe L, Miller M, Frost C, Laney Z, Eke R.

J Pediatr Gastroenterol Nutr. 2018 Jun;66(6):893-897. doi: 10.1097/MPG.0000000000001840.


Ruthenium catalyzed remote C4-selective C-H functionalisation of carbazoles via σ-activation.

Leitch JA, Heron CJ, McKnight J, Kociok-Köhn G, Bhonoah Y, Frost CG.

Chem Commun (Camb). 2017 Dec 5;53(97):13039-13042. doi: 10.1039/c7cc07606a.


Ruthenium-catalysed σ-activation for remote meta-selective C-H functionalisation.

Leitch JA, Frost CG.

Chem Soc Rev. 2017 Dec 7;46(23):7145-7153. doi: 10.1039/c7cs00496f. Epub 2017 Oct 17.


Ruthenium-Catalyzed para-Selective C-H Alkylation of Aniline Derivatives.

Leitch JA, McMullin CL, Paterson AJ, Mahon MF, Bhonoah Y, Frost CG.

Angew Chem Int Ed Engl. 2017 Nov 20;56(47):15131-15135. doi: 10.1002/anie.201708961. Epub 2017 Oct 24.


Nanoformulation of Leonotis leonurus to improve its bioavailability as a potential antidiabetic drug.

Odei-Addo F, Shegokar R, Müller RH, Levendal RA, Frost C.

3 Biotech. 2017 Oct;7(5):344. doi: 10.1007/s13205-017-0986-0. Epub 2017 Sep 23.


Design optimization for clinical trials in early-stage manifest Huntington's disease.

Frost C, Mulick A, Scahill RI, Owen G, Aylward E, Leavitt BR, Durr A, Roos RAC, Borowsky B, Stout JC, Reilmann R, Langbehn DR, Tabrizi SJ, Sampaio C; TRACK-HD Investigators.

Mov Disord. 2017 Nov;32(11):1610-1619. doi: 10.1002/mds.27122. Epub 2017 Sep 14.


Reversal of apixaban anticoagulation by four-factor prothrombin complex concentrates in healthy subjects: a randomized three-period crossover study.

Song Y, Wang Z, Perlstein I, Wang J, LaCreta F, Frost RJA, Frost C.

J Thromb Haemost. 2017 Nov;15(11):2125-2137. doi: 10.1111/jth.13815. Epub 2017 Oct 9.


Ratiometric electrochemical detection of β-galactosidase.

Spring SA, Goggins S, Frost CG.

Org Biomol Chem. 2017 Aug 30;15(34):7122-7126. doi: 10.1039/c7ob01593c.


Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial magnetic resonance imaging study.

Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway SP, Correia S, Sperling RA, Chhatwal JP, Mayeux RP, Brickman AM, Martins RN, Farlow MR, Ghetti B, Saykin AJ, Jack CR Jr, Schofield PR, McDade E, Weiner MW, Ringman JM, Thompson PM, Masters CL, Rowe CC, Rossor MN, Ourselin S, Fox NC; Dominantly Inherited Alzheimer Network (DIAN).

Alzheimers Dement. 2018 Jan;14(1):43-53. doi: 10.1016/j.jalz.2017.06.2268. Epub 2017 Jul 22.


Key aromatic/hydrophobic amino acids controlling a cross-amyloid peptide interaction versus amyloid self-assembly.

Bakou M, Hille K, Kracklauer M, Spanopoulou A, Frost CV, Malideli E, Yan LM, Caporale A, Zacharias M, Kapurniotu A.

J Biol Chem. 2017 Sep 1;292(35):14587-14602. doi: 10.1074/jbc.M117.774893. Epub 2017 Jul 6.


Community health promotion and medical provision for neonatal health-CHAMPION cluster randomised trial in Nagarkurnool district, Telangana (formerly Andhra Pradesh), India.

Boone P, Eble A, Elbourne D, Frost C, Jayanty C, Lakshminarayana R, Mann V, Mukherjee R, Piaggio G, Reddy P.

PLoS Med. 2017 Jul 5;14(7):e1002324. doi: 10.1371/journal.pmed.1002324. eCollection 2017 Jul.


α-Halo carbonyls enable meta selective primary, secondary and tertiary C-H alkylations by ruthenium catalysis.

Paterson AJ, Heron CJ, McMullin CL, Mahon MF, Press NJ, Frost CG.

Org Biomol Chem. 2017 Jul 19;15(28):5993-6000. doi: 10.1039/c7ob01192j.


Linked symptom monitoring and depression treatment programmes for specialist cancer services: protocol for a mixed-methods implementation study.

Wanat M, Walker J, Burke K, Sevdalis N, Richardson A, Mulick A, Frost C, Sharpe M.

BMJ Open. 2017 Jul 2;7(6):e016186. doi: 10.1136/bmjopen-2017-016186.


Re: The accuracy of emergency abdominal CT in adult patients who present with non-traumatic abdominal pain: results of a UK national audit. A reply.

Howlett DC, Drinkwater K, Frost C, Higginson A, Ball C, Maskell G.

Clin Radiol. 2017 Oct;72(10):897. doi: 10.1016/j.crad.2017.05.011. Epub 2017 Jun 22. No abstract available.


Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone.

Podewin T, Broichhagen J, Frost C, Groneberg D, Ast J, Meyer-Berg H, Fine NHF, Friebe A, Zacharias M, Hodson DJ, Trauner D, Hoffmann-Röder A.

Chem Sci. 2017 Jun 1;8(6):4644-4653. doi: 10.1039/c6sc05044a. Epub 2017 Apr 19.

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