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Exocyst structural changes associated with activation of tethering downstream of Rho/Cdc42 GTPases.

Rossi G, Lepore D, Kenner L, Czuchra AB, Plooster M, Frost A, Munson M, Brennwald P.

J Cell Biol. 2020 Feb 3;219(2). pii: e201904161. doi: 10.1083/jcb.201904161.


Mechanical circulatory support in cardiogenic shock.

Frost A, Haddad H, Shavadia J.

Curr Opin Cardiol. 2019 Dec 27. doi: 10.1097/HCO.0000000000000715. [Epub ahead of print]


Outcomes of kidney transplantation using deceased donors with history of diabetes.

Khan FN, Truong LD, Nguyen DT, Graviss EA, Bhatti MI, Frost AE, Osama Gaber A, Suki WN.

Clin Transplant. 2019 Dec 21:e13775. doi: 10.1111/ctr.13775. [Epub ahead of print]


Developmental pathways from preschool irritability to multifinality in early adolescence: the role of diurnal cortisol.

Kessel EM, Frost A, Goldstein BL, Black SR, Dougherty LR, Carlson GA, Klein DN.

Psychol Med. 2019 Dec 20:1-9. doi: 10.1017/S0033291719003684. [Epub ahead of print]


The Importance of 1,5-Oxygen---Chalcogen Interactions in Enantioselective Isochalcogenourea Catalysis.

Young C, Elmi A, Pascoe D, Morris R, McLaughlin C, Woods A, Frost A, De La Houpliere A, Ling K, Smith T, Slawin A, Willoughby P, Cockroft S, Smith AD.

Angew Chem Int Ed Engl. 2019 Dec 19. doi: 10.1002/anie.201914421. [Epub ahead of print]


Results of an Expert Consensus Survey on the Treatment of Pulmonary Arterial Hypertension With Oral Prostacyclin Pathway Agents.

McLaughlin VV, Channick R, De Marco T, Farber HW, Gaine S, Galié N, Krasuski RA, Preston I, Souza R, Coghlan JG, Frantz RP, Hemnes A, Kim NH, Lang IM, Langleben D, Li M, Sitbon O, Tapson V, Frost A.

Chest. 2019 Nov 16. pii: S0012-3692(19)34214-X. doi: 10.1016/j.chest.2019.10.043. [Epub ahead of print]


Patients with pulmonary arterial hypertension with and without cardiovascular risk factors: Results from the AMBITION trial.

McLaughlin VV, Vachiery JL, Oudiz RJ, Rosenkranz S, Galiè N, Barberà JA, Frost AE, Ghofrani HA, Peacock AJ, Simonneau G, Rubin LJ, Blair C, Langley J, Hoeper MM; AMBITION Study Group.

J Heart Lung Transplant. 2019 Dec;38(12):1286-1295. doi: 10.1016/j.healun.2019.09.010. Epub 2019 Sep 17.


Multivariate Analysis of Electrophysiological Signals Reveals the Temporal Properties of Visuomotor Computations for Precision Grips.

Guo LL, Nestor A, Nemrodov D, Frost A, Niemeier M.

J Neurosci. 2019 Nov 27;39(48):9585-9597. doi: 10.1523/JNEUROSCI.0914-19.2019. Epub 2019 Oct 18.


Current outcomes when optimizing 'standard' sample preparation for single-particle cryo-EM.

Carragher B, Cheng Y, Frost A, Glaeser RM, Lander GC, Nogales E, Wang HW.

J Microsc. 2019 Oct;276(1):39-45. doi: 10.1111/jmi.12834. Epub 2019 Oct 7.


The Effect of Divalent Cations on the Thermostability of Type II Polyketide Synthase Acyl Carrier Proteins.

Rivas M, Courouble VC, Baker MC, Cookmeyer DL, Fiore KE, Frost AJ, Godbe KN, Jordan MR, Krasnow EN, Mollo A, Ridings ST, Sawada K, Shroff KD, Studnitzer B, Thiele GAR, Sisto AC, Nawaal S, Huff AR, Fairman R, Johnson KA, Beld J, Kokona B, Charkoudian LK.

AIChE J. 2018 Dec;64(12):4308-4318. doi: 10.1002/aic.16402. Epub 2018 Sep 8.


Clinical outcomes stratified by baseline functional class after initial combination therapy for pulmonary arterial hypertension.

White RJ, Vonk-Noordegraaf A, Rosenkranz S, Oudiz RJ, McLaughlin VV, Hoeper MM, Grünig E, Ghofrani HA, Chakinala MM, Barberà JA, Blair C, Langley J, Frost AE.

Respir Res. 2019 Sep 12;20(1):208. doi: 10.1186/s12931-019-1180-1.


Working memory in action: inspecting the systematic and unsystematic errors of spatial memory across saccades.

Frost A, Tomou G, Parikh H, Kaur J, Zivcevska M, Niemeier M.

Exp Brain Res. 2019 Nov;237(11):2939-2956. doi: 10.1007/s00221-019-05623-x. Epub 2019 Sep 10.


Single-stage tubular urethral reconstruction using oral grafts is an alternative to classical staged approach for selected penile urethral strictures.

Campos-Juanatey F, Bugeja S, Dragova M, Frost AV, Ivaz SL, Andrich DE, Mundy AR.

Asian J Androl. 2019 Aug 2. doi: 10.4103/aja.aja_78_19. [Epub ahead of print]


A Tunable Microfluidic Device Enables Cargo Encapsulation by Cell- or Organelle-Sized Lipid Vesicles Comprising Asymmetric Lipid Bilayers.

Romanov V, McCullough J, Gale BK, Frost A.

Adv Biosyst. 2019 Jul;3(7). pii: 1900010. doi: 10.1002/adbi.201900010. Epub 2019 May 27.


Open and cut: allosteric motion and membrane fission by dynamin superfamily proteins.

Kalia R, Frost A.

Mol Biol Cell. 2019 Aug 1;30(17):2097-2104. doi: 10.1091/mbc.E16-10-0709.


Funneling of the bladder neck - radiological appearance after radical retropubic prostatectomy and clinical relevance.

Bugeja S, Frost A, Ivaz S, Campos F, Andrich DE, Mundy AR.

Asian J Androl. 2019 Jul 9. doi: 10.4103/aja.aja_73_19. [Epub ahead of print] No abstract available.


Syringoceles of Cowper's ducts and glands in adult men.

Bugeja S, Frost A, Ivaz S, Dragova M, Andrich DE, Mundy AR.

Asian J Androl. 2019 Jul 2. doi: 10.4103/aja.aja_59_19. [Epub ahead of print]


United States Pulmonary Hypertension Scientific Registry (USPHSR): rationale, design, and clinical implications.

Elliott CG, Austin ED, Badesch D, Badlam J, Benza RL, Chung WK, Farber HW, Feldkircher K, Frost AE, Poms AD, Lutz KA, Pauciulo MW, Yu C, Nichols WC.

Pulm Circ. 2019 Apr-Jun;9(2):2045894019851696. doi: 10.1177/2045894019851696.


Enhancement of Consonant Recognition in Bimodal and Normal Hearing Listeners.

Yoon YS, Riley B, Patel H, Frost A, Fillmore P, Gifford R, Hansen J.

Ann Otol Rhinol Laryngol. 2019 Jun;128(6_suppl):139S-145S. doi: 10.1177/0003489419832625.


Altering standard admission order sets to promote clinical laboratory stewardship: a cohort quality improvement study.

Leis B, Frost A, Bryce R, Lyon AW, Coverett K.

BMJ Qual Saf. 2019 Oct;28(10):846-852. doi: 10.1136/bmjqs-2018-008995. Epub 2019 May 9.


Acute Angle-Closure Glaucoma Secondary to a Phakic Intraocular Lens, an Ophthalmic Emergency.

Frost A, Ritter DJ, Trotter A, Pulia MS.

Clin Pract Cases Emerg Med. 2019 Mar 5;3(2):137-139. doi: 10.5811/cpcem.2019.1.41399. eCollection 2019 May.


eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.

Kenner LR, Anand AA, Nguyen HC, Myasnikov AG, Klose CJ, McGeever LA, Tsai JC, Miller-Vedam LE, Walter P, Frost A.

Science. 2019 May 3;364(6439):491-495. doi: 10.1126/science.aaw2922.


Predictors of Overnight Admission After Laparoscopic Myomectomy in a High-Volume Minimally Invasive Gynecologic Surgery Setting.

Moawad G, Park D, Maasen M, Frost A, Tyan P.

J Minim Invasive Gynecol. 2020 Jan;27(1):195-199. doi: 10.1016/j.jmig.2019.03.022. Epub 2019 Mar 29.


Latent profiles of maternal neural response to infant emotional stimuli: Associations with maternal sensitivity.

Kuzava S, Nissim G, Frost A, Nelson B, Bernard K.

Biol Psychol. 2019 Apr;143:113-120. doi: 10.1016/j.biopsycho.2019.02.009. Epub 2019 Feb 22.


Predicting Survival in Patients With Pulmonary Arterial Hypertension: The REVEAL Risk Score Calculator 2.0 and Comparison With ESC/ERS-Based Risk Assessment Strategies.

Benza RL, Gomberg-Maitland M, Elliott CG, Farber HW, Foreman AJ, Frost AE, McGoon MD, Pasta DJ, Selej M, Burger CD, Frantz RP.

Chest. 2019 Aug;156(2):323-337. doi: 10.1016/j.chest.2019.02.004. Epub 2019 Feb 14.


The combined survival effect of codon 72 polymorphisms and p53 somatic mutations in breast cancer depends on race and molecular subtype.

Hebert-Magee S, Yu H, Behring M, Jadhav T, Shanmugam C, Frost A, Eltoum IE, Varambally S, Manne U.

PLoS One. 2019 Feb 7;14(2):e0211734. doi: 10.1371/journal.pone.0211734. eCollection 2019.


Where Australia's Better Access scheme has had an impact on mental health: A commentary on Jorm (2018).

Lee CW, Frost AD.

Aust N Z J Psychiatry. 2019 Mar;53(3):259-261. doi: 10.1177/0004867419828495. Epub 2019 Feb 7. No abstract available.


Functional role of PGAM5 multimeric assemblies and their polymerization into filaments.

Ruiz K, Thaker TM, Agnew C, Miller-Vedam L, Trenker R, Herrera C, Ingaramo M, Toso D, Frost A, Jura N.

Nat Commun. 2019 Jan 31;10(1):531. doi: 10.1038/s41467-019-08393-w.


Secure attachment predicts lower body mass index in young children with histories of child protective services involvement.

Bernard K, Frost A, Jelinek C, Dozier M.

Pediatr Obes. 2019 Jul;14(7):e12510. doi: 10.1111/ijpo.12510. Epub 2019 Jan 18.


Rates of regression of cervical dysplasia between initial biopsy and excisional procedure in routine clinical practice.

Mark K, Frost A, Hussey H, Lopez-Acevedo M, Burke AE, Edwardson J, Solaru O, Gravitt P.

Arch Gynecol Obstet. 2019 Mar;299(3):841-846. doi: 10.1007/s00404-018-5026-8. Epub 2019 Jan 4.


How Synthetic Biology and Metabolic Engineering Can Boost the Generation of Artificial Blood Using Microbial Production Hosts.

Frost AT, Jacobsen IH, Worberg A, Martínez JL.

Front Bioeng Biotechnol. 2018 Nov 30;6:186. doi: 10.3389/fbioe.2018.00186. eCollection 2018. Review.


Diagnosis of pulmonary hypertension.

Frost A, Badesch D, Gibbs JSR, Gopalan D, Khanna D, Manes A, Oudiz R, Satoh T, Torres F, Torbicki A.

Eur Respir J. 2019 Jan 24;53(1). pii: 1801904. doi: 10.1183/13993003.01904-2018. Print 2019 Jan.


Initial combination therapy with ambrisentan + tadalafil on pulmonary arterial hypertension‒related hospitalization in the AMBITION trial.

Vachiéry JL, Galiè N, Barberá JA, Frost AE, Ghofrani HA, Hoeper MM, McLaughlin VV, Peacock AJ, Simonneau G, Blair C, Miller KL, Langley J, Rubin LJ; AMBITION Study Group.

J Heart Lung Transplant. 2019 Feb;38(2):194-202. doi: 10.1016/j.healun.2018.11.006. Epub 2018 Nov 22.


Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.

Rhodes CJ, Batai K, Bleda M, Haimel M, Southgate L, Germain M, Pauciulo MW, Hadinnapola C, Aman J, Girerd B, Arora A, Knight J, Hanscombe KB, Karnes JH, Kaakinen M, Gall H, Ulrich A, Harbaum L, Cebola I, Ferrer J, Lutz K, Swietlik EM, Ahmad F, Amouyel P, Archer SL, Argula R, Austin ED, Badesch D, Bakshi S, Barnett C, Benza R, Bhatt N, Bogaard HJ, Burger CD, Chakinala M, Church C, Coghlan JG, Condliffe R, Corris PA, Danesino C, Debette S, Elliott CG, Elwing J, Eyries M, Fortin T, Franke A, Frantz RP, Frost A, Garcia JGN, Ghio S, Ghofrani HA, Gibbs JSR, Harley J, He H, Hill NS, Hirsch R, Houweling AC, Howard LS, Ivy D, Kiely DG, Klinger J, Kovacs G, Lahm T, Laudes M, Machado RD, MacKenzie Ross RV, Marsolo K, Martin LJ, Moledina S, Montani D, Nathan SD, Newnham M, Olschewski A, Olschewski H, Oudiz RJ, Ouwehand WH, Peacock AJ, Pepke-Zaba J, Rehman Z, Robbins I, Roden DM, Rosenzweig EB, Saydain G, Scelsi L, Schilz R, Seeger W, Shaffer CM, Simms RW, Simon M, Sitbon O, Suntharalingam J, Tang H, Tchourbanov AY, Thenappan T, Torres F, Toshner MR, Treacy CM, Vonk Noordegraaf A, Waisfisz Q, Walsworth AK, Walter RE, Wharton J, White RJ, Wilt J, Wort SJ, Yung D, Lawrie A, Humbert M, Soubrier F, Trégouët DA, Prokopenko I, Kittles R, Gräf S, Nichols WC, Trembath RC, Desai AA, Morrell NW, Wilkins MR; UK NIHR BioResource Rare Diseases Consortium; UK PAH Cohort Study Consortium; US PAH Biobank Consortium.

Lancet Respir Med. 2019 Mar;7(3):227-238. doi: 10.1016/S2213-2600(18)30409-0. Epub 2018 Dec 5.


Synthesis and Derivatization of 1,1-[18 F]Difluorinated Alkenes.

Frost AB, Brambilla M, Exner RM, Tredwell M.

Angew Chem Int Ed Engl. 2019 Jan 8;58(2):472-476. doi: 10.1002/anie.201810413. Epub 2018 Dec 6.


Extreme lateral interbody fusion (XLIF) as a treatment for acute spondylodiscitis: Leeds spinal unit experience.

Timothy J, Pal D, Akhunbay-Fudge C, Knights M, Frost A, Derham C, Selvanathan S.

J Clin Neurosci. 2019 Jan;59:213-217. doi: 10.1016/j.jocn.2018.10.063. Epub 2018 Nov 6.



Frantz RP, Zhao C, Farber HW, Badesch DB, Elliott CG, Frost AE, McGoon MD, Mink DR, Selej M, Benza RL.

Chest. 2018 Nov;154(5):1262-1264. doi: 10.1016/j.chest.2018.07.033. No abstract available.


Acetylation of ACAP4 regulates CCL18-elicited breast cancer cell migration and invasion.

Song X, Liu W, Yuan X, Jiang J, Wang W, Mullen M, Zhao X, Zhang Y, Liu F, Du S, Rehman A, Tian R, Li J, Frost A, Song Z, Green HN, Henry C, Liu X, Ding X, Wang D, Yao X.

J Mol Cell Biol. 2018 Dec 1;10(6):559-572. doi: 10.1093/jmcb/mjy058.


Safety and tolerability of transition from inhaled treprostinil to oral selexipag in pulmonary arterial hypertension: Results from the TRANSIT-1 study.

Frost A, Janmohamed M, Fritz JS, McConnell JW, Poch D, Fortin TA, Miller CE, Chin KM, Fisher M, Eggert M, McEvoy C, Benza RL, Farber HW, Kim NH, Pfister T, Shiraga Y, McLaughlin V.

J Heart Lung Transplant. 2019 Jan;38(1):43-50. doi: 10.1016/j.healun.2018.09.003. Epub 2018 Sep 12.


Homotypic and heterotypic continuity of internalizing and externalizing symptoms from ages 3 to 12: The moderating role of diurnal cortisol.

Frost A, Kessel E, Black S, Goldstein B, Bernard K, Klein DN.

Dev Psychopathol. 2019 May;31(2):789-798. doi: 10.1017/S0954579418000573. Epub 2018 Sep 25.


Health Care Spending Under Employer-Sponsored Insurance: A 10-Year Retrospective.

Frost A, Barrette E, Kennedy K, Brennan N.

Health Aff (Millwood). 2018 Oct;37(10):1623-1631. doi: 10.1377/hlthaff.2018.0481. Epub 2018 Sep 19.


Risk-stratified outcomes with initial combination therapy in pulmonary arterial hypertension: Application of the REVEAL risk score.

Frost AE, Hoeper MM, Barberá JA, Vachiery JL, Blair C, Langley J, Rubin LJ.

J Heart Lung Transplant. 2018 Dec;37(12):1410-1417. doi: 10.1016/j.healun.2018.07.001. Epub 2018 Sep 9.


Structures, Functions, and Dynamics of ESCRT-III/Vps4 Membrane Remodeling and Fission Complexes.

McCullough J, Frost A, Sundquist WI.

Annu Rev Cell Dev Biol. 2018 Oct 6;34:85-109. doi: 10.1146/annurev-cellbio-100616-060600. Epub 2018 Aug 10. Review.


FDM 3D Printing of High-Pressure, Heat-Resistant, Transparent Microfluidic Devices.

Romanov V, Samuel R, Chaharlang M, Jafek AR, Frost A, Gale BK.

Anal Chem. 2018 Sep 4;90(17):10450-10456. doi: 10.1021/acs.analchem.8b02356. Epub 2018 Aug 17.


Therapeutic Engagement and Treatment Progress: Developing and Testing an In-Treatment Measure of Client Engagement Among Sex Offenders in a Group Program.

Frost A, Grace RC, McLean AP.

Sex Abuse. 2019 Dec;31(8):952-971. doi: 10.1177/1079063218791178. Epub 2018 Jul 27.


HIV-1 Transmission Clustering and Phylodynamics Highlight the Important Role of Young Men Who Have Sex with Men.

Dennis AM, Volz E, Frost ASMSDW, Hossain M, Poon AFY, Rebeiro PF, Vermund SH, Sterling TR, Kalish ML.

AIDS Res Hum Retroviruses. 2018 Oct;34(10):879-888. doi: 10.1089/AID.2018.0039. Epub 2018 Aug 23.


Structural basis of mitochondrial receptor binding and constriction by DRP1.

Kalia R, Wang RY, Yusuf A, Thomas PV, Agard DA, Shaw JM, Frost A.

Nature. 2018 Jun;558(7710):401-405. doi: 10.1038/s41586-018-0211-2. Epub 2018 Jun 13.


Vms1p is a release factor for the ribosome-associated quality control complex.

Zurita Rendón O, Fredrickson EK, Howard CJ, Van Vranken J, Fogarty S, Tolley ND, Kalia R, Osuna BA, Shen PS, Hill CP, Frost A, Rutter J.

Nat Commun. 2018 Jun 6;9(1):2197. doi: 10.1038/s41467-018-04564-3.


Direct Organocatalytic Enantioselective Functionalization of SiOx Surfaces.

Parkin JD, Chisholm R, Frost AB, Bailey RG, Smith AD, Hähner G.

Angew Chem Int Ed Engl. 2018 Jul 20;57(30):9377-9381. doi: 10.1002/anie.201804814. Epub 2018 Jun 29.


The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.

Shurtleff MJ, Itzhak DN, Hussmann JA, Schirle Oakdale NT, Costa EA, Jonikas M, Weibezahn J, Popova KD, Jan CH, Sinitcyn P, Vembar SS, Hernandez H, Cox J, Burlingame AL, Brodsky JL, Frost A, Borner GH, Weissman JS.

Elife. 2018 May 29;7. pii: e37018. doi: 10.7554/eLife.37018.

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