Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 152

1.

Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.

Regenass P, Abboud D, Daubeuf F, Lehalle C, Gizzi P, Riché S, Hachet-Haas M, Rohmer F, Gasparik V, Boeglin D, Haiech J, Knehans T, Rognan D, Heissler D, Marsol C, Villa P, Galzi JL, Hibert M, Frossard N, Bonnet D.

J Med Chem. 2018 Sep 13;61(17):7671-7686. doi: 10.1021/acs.jmedchem.8b00657. Epub 2018 Aug 28.

PMID:
30106292
2.

Optimising experimental research in respiratory diseases: an ERS statement.

Bonniaud P, Fabre A, Frossard N, Guignabert C, Inman M, Kuebler WM, Maes T, Shi W, Stampfli M, Uhlig S, White E, Witzenrath M, Bellaye PS, Crestani B, Eickelberg O, Fehrenbach H, Guenther A, Jenkins G, Joos G, Magnan A, Maitre B, Maus UA, Reinhold P, Vernooy JHJ, Richeldi L, Kolb M.

Eur Respir J. 2018 May 17;51(5). pii: 1702133. doi: 10.1183/13993003.02133-2017. Print 2018 May.

PMID:
29773606
3.

A bifunctional-biased mu-opioid agonist-neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects.

Drieu la Rochelle A, Guillemyn K, Dumitrascuta M, Martin C, Utard V, Quillet R, Schneider S, Daubeuf F, Willemse T, Mampuys P, Maes BUW, Frossard N, Bihel F, Spetea M, Simonin F, Ballet S.

Pain. 2018 Sep;159(9):1705-1718. doi: 10.1097/j.pain.0000000000001262.

PMID:
29708942
4.

Decreased Migration of Dendritic Cells into the Jugular-Nodose Ganglia by the CXCL12 Neutraligand Chalcone 4 in Ovalbumin-Sensitized Asthmatic Mice.

Heck S, Daubeuf F, Le DD, Sester M, Bonnet D, Bals R, Frossard N, Dinh QT.

Neuroimmunomodulation. 2017;24(6):331-340. doi: 10.1159/000487140. Epub 2018 Apr 20.

PMID:
29680839
5.

Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation.

Bollenbach M, Salvat E, Daubeuf F, Wagner P, Yalcin I, Humo M, Letellier B, Becker LJ, Bihel F, Bourguignon JJ, Villa P, Obrecht A, Frossard N, Barrot M, Schmitt M.

Eur J Med Chem. 2018 Mar 10;147:163-182. doi: 10.1016/j.ejmech.2018.01.049. Epub 2018 Jan 31. Review.

PMID:
29432948
6.

Towards targeting resolution pathways of airway inflammation in asthma.

Barnig C, Frossard N, Levy BD.

Pharmacol Ther. 2018 Jun;186:98-113. doi: 10.1016/j.pharmthera.2018.01.004. Epub 2018 Jan 20. Review.

PMID:
29352860
7.

Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy.

Tavakoli R, Nemska S, Jamshidi P, Gassmann M, Frossard N.

J Vis Exp. 2017 Sep 25;(127). doi: 10.3791/56231.

PMID:
28994784
8.

The role of 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors.

Ayme-Dietrich E, Lawson R, Côté F, de Tapia C, Da Silva S, Ebel C, Hechler B, Gachet C, Guyonnet J, Rouillard H, Stoltz J, Quentin E, Banas S, Daubeuf F, Frossard N, Gasser B, Mazzucotelli JP, Hermine O, Maroteaux L, Monassier L.

Br J Pharmacol. 2017 Nov;174(22):4123-4139. doi: 10.1111/bph.13981. Epub 2017 Oct 15.

9.

A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.

Daubeuf F, Becker J, Aguilar-Pimentel JA, Ebel C, Hrabě de Angelis M, Hérault Y, Frossard N.

Curr Protoc Mouse Biol. 2017 Jun 19;7(2):88-99. doi: 10.1002/cpmo.26.

PMID:
28628216
10.

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling.

Dong J, Aulestia FJ, Assad Kahn S, Zeniou M, Dubois LG, El-Habr EA, Daubeuf F, Tounsi N, Cheshier SH, Frossard N, Junier MP, Chneiweiss H, Néant I, Moreau M, Leclerc C, Haiech J, Kilhoffer MC.

Biochim Biophys Acta Mol Cell Res. 2017 Jun;1864(6):1018-1027. doi: 10.1016/j.bbamcr.2017.01.010. Epub 2017 Jan 18.

11.

Increase of Mast Cell-Nerve Association and Neuropeptide Receptor Expression on Mast Cells in Perennial Allergic Rhinitis.

Le DD, Schmit D, Heck S, Omlor AJ, Sester M, Herr C, Schick B, Daubeuf F, Fähndrich S, Bals R, Frossard N, Al Kadah B, Dinh QT.

Neuroimmunomodulation. 2016;23(5-6):261-270. doi: 10.1159/000453068. Epub 2016 Dec 29.

PMID:
28030866
12.

Kinetic mRNA Profiling in a Rat Model of Left-Ventricular Hypertrophy Reveals Early Expression of Chemokines and Their Receptors.

Nemska S, Monassier L, Gassmann M, Frossard N, Tavakoli R.

PLoS One. 2016 Aug 15;11(8):e0161273. doi: 10.1371/journal.pone.0161273. eCollection 2016.

13.

Revascularization of the graft in obliterative bronchiolitis after heterotopic tracheal transplantation.

Nemska S, Daubeuf F, Frossard N.

Physiol Rep. 2016 Feb;4(4). pii: e12690. doi: 10.14814/phy2.12690.

14.

A strategy to discover decoy chemokine ligands with an anti-inflammatory activity.

Abboud D, Daubeuf F, Do QT, Utard V, Villa P, Haiech J, Bonnet D, Hibert M, Bernard P, Galzi JL, Frossard N.

Sci Rep. 2015 Oct 7;5:14746. doi: 10.1038/srep14746.

15.

Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.

Flacher V, Neuberg P, Point F, Daubeuf F, Muller Q, Sigwalt D, Fauny JD, Remy JS, Frossard N, Wagner A, Mueller CG, Schaeffer E.

ACS Chem Biol. 2015 Dec 18;10(12):2697-705. doi: 10.1021/acschembio.5b00552. Epub 2015 Sep 30.

PMID:
26389521
16.

Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation.

Daubeuf F, Jung F, Douglas GJ, Chevalier E, Frossard N.

Respir Res. 2015 Jun 27;16:77. doi: 10.1186/s12931-015-0231-5.

17.

Discovery and characterization of an endogenous CXCR4 antagonist.

Zirafi O, Kim KA, Ständker L, Mohr KB, Sauter D, Heigele A, Kluge SF, Wiercinska E, Chudziak D, Richter R, Moepps B, Gierschik P, Vas V, Geiger H, Lamla M, Weil T, Burster T, Zgraja A, Daubeuf F, Frossard N, Hachet-Haas M, Heunisch F, Reichetzeder C, Galzi JL, Pérez-Castells J, Canales-Mayordomo A, Jiménez-Barbero J, Giménez-Gallego G, Schneider M, Shorter J, Telenti A, Hocher B, Forssmann WG, Bonig H, Kirchhoff F, Münch J.

Cell Rep. 2015 May 5;11(5):737-47. doi: 10.1016/j.celrep.2015.03.061. Epub 2015 Apr 23.

18.

Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue.

Beck IM, Van Crombruggen K, Holtappels G, Daubeuf F, Frossard N, Bachert C, De Bosscher K.

PLoS One. 2015 Apr 13;10(4):e0123068. doi: 10.1371/journal.pone.0123068. eCollection 2015.

19.

Full-root aortic valve replacement with stentless xenograft achieves superior regression of left ventricular hypertrophy compared to pericardial stented aortic valves.

Tavakoli R, Auf der Maur C, Mueller X, Schläpfer R, Jamshidi P, Daubeuf F, Frossard N.

J Cardiothorac Surg. 2015 Feb 3;10:15. doi: 10.1186/s13019-015-0219-8.

20.

Eosinophils and the ovalbumin mouse model of asthma.

Daubeuf F, Frossard N.

Methods Mol Biol. 2014;1178:283-93. doi: 10.1007/978-1-4939-1016-8_24.

PMID:
24986625
21.

Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway.

Daryadel A, Bogdanova A, Gassmann M, Mueller X, Zünd G, Seifert B, Lehalle C, Frossard N, Tavakoli R.

J Cardiothorac Surg. 2014 May 9;9:81. doi: 10.1186/1749-8090-9-81.

22.

Targeting mast cells in inflammatory diseases.

Reber LL, Frossard N.

Pharmacol Ther. 2014 Jun;142(3):416-35. doi: 10.1016/j.pharmthera.2014.01.004. Epub 2014 Jan 31. Review.

PMID:
24486828
23.

Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism.

Reber LL, Daubeuf F, Pejler G, Abrink M, Frossard N.

J Immunol. 2014 Feb 15;192(4):1847-54. doi: 10.4049/jimmunol.1300875. Epub 2014 Jan 22.

24.

Cold ischemia with selective anterograde in situ pulmonary perfusion preserves gas exchange and mitochondrial homeostasis and curbs inflammation in an experimental model of donation after cardiac death.

Pottecher J, Santelmo N, Noll E, Charles AL, Benahmed M, Canuet M, Frossard N, Namer IJ, Geny B, Massard G, Diemunsch P.

Transpl Int. 2013 Oct;26(10):1027-37. doi: 10.1111/tri.12157. Epub 2013 Jul 29.

25.

An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice.

Daubeuf F, Hachet-Haas M, Gizzi P, Gasparik V, Bonnet D, Utard V, Hibert M, Frossard N, Galzi JL.

J Biol Chem. 2013 Apr 26;288(17):11865-76. doi: 10.1074/jbc.M112.449348. Epub 2013 Feb 28.

26.

NMR HRMAS spectroscopy of lung biopsy samples: Comparison study between human, pig, rat, and mouse metabolomics.

Benahmed MA, Elbayed K, Daubeuf F, Santelmo N, Frossard N, Namer IJ.

Magn Reson Med. 2014 Jan;71(1):35-43. doi: 10.1002/mrm.24658. Epub 2013 Feb 14.

27.

Acute Asthma Models to Ovalbumin in the Mouse.

Daubeuf F, Frossard N.

Curr Protoc Mouse Biol. 2013 Mar 1;3(1):31-7. doi: 10.1002/9780470942390.mo120202.

PMID:
26069022
28.

The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthma.

Reber LL, Daubeuf F, Nemska S, Frossard N.

PLoS One. 2012;7(11):e49512. doi: 10.1371/journal.pone.0049512. Epub 2012 Nov 26.

29.

A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma.

Reber LL, Daubeuf F, Plantinga M, De Cauwer L, Gerlo S, Waelput W, Van Calenbergh S, Tavernier J, Haegeman G, Lambrecht BN, Frossard N, De Bosscher K.

J Immunol. 2012 Apr 1;188(7):3478-87. doi: 10.4049/jimmunol.1004227. Epub 2012 Mar 5.

30.

Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo.

Gasparik V, Daubeuf F, Hachet-Haas M, Rohmer F, Gizzi P, Haiech J, Galzi JL, Hibert M, Bonnet D, Frossard N.

ACS Med Chem Lett. 2011 Dec 9;3(1):10-4. doi: 10.1021/ml200017d. eCollection 2012 Jan 12.

31.

Performing Bronchoalveolar Lavage in the Mouse.

Daubeuf F, Frossard N.

Curr Protoc Mouse Biol. 2012 Jun 1;2(2):167-75. doi: 10.1002/9780470942390.mo110201.

PMID:
26069010
32.

The assessment of the quality of the graft in an animal model for lung transplantation using the metabolomics 1H high-resolution magic angle spinning NMR spectroscopy.

Benahmed MA, Santelmo N, Elbayed K, Frossard N, Noll E, Canuet M, Pottecher J, Diemunsch P, Piotto M, Massard G, Namer IJ.

Magn Reson Med. 2012 Oct;68(4):1026-38. doi: 10.1002/mrm.24110. Epub 2011 Dec 9.

33.

The peroxisome proliferator-activated receptor α agonist fenofibrate decreases airway reactivity to methacholine and increases endothelial nitric oxide synthase phosphorylation in mouse lung.

Becker J, Delayre-Orthez C, Frossard N, Pons F.

Fundam Clin Pharmacol. 2012 Jun;26(3):340-6. doi: 10.1111/j.1472-8206.2011.00935.x. Epub 2011 Mar 11.

PMID:
21392098
34.

Genetic and pharmacological evaluation of cathepsin s in a mouse model of asthma.

Deschamps K, Cromlish W, Weicker S, Lamontagne S, Huszar SL, Gauthier JY, Mudgett JS, Guimond A, Romand R, Frossard N, Percival MD, Slipetz D, Tan CM.

Am J Respir Cell Mol Biol. 2011 Jul;45(1):81-7. doi: 10.1165/rcmb.2009-0392OC. Epub 2010 Sep 20.

PMID:
20855652
35.

[Respiratory research conference 2009].

Frossard N, Crestani B.

Rev Mal Respir. 2010 Mar;27(3):283-4. doi: 10.1016/j.rmr.2010.03.008. French. No abstract available.

PMID:
20359624
36.

Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications.

Galzi JL, Hachet-Haas M, Bonnet D, Daubeuf F, Lecat S, Hibert M, Haiech J, Frossard N.

Pharmacol Ther. 2010 Apr;126(1):39-55. doi: 10.1016/j.pharmthera.2009.12.003. Epub 2010 Feb 1. Review.

PMID:
20117133
37.

Activation of the lung S1P(1) receptor reduces allergen-induced plasma leakage in mice.

Blé FX, Cannet C, Zurbruegg S, Gérard C, Frossard N, Beckmann N, Trifilieff A.

Br J Pharmacol. 2009 Nov;158(5):1295-301. doi: 10.1111/j.1476-5381.2009.00391.x. Epub 2009 Sep 25.

38.

Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation.

Reber L, Vermeulen L, Haegeman G, Frossard N.

PLoS One. 2009;4(2):e4393. doi: 10.1371/journal.pone.0004393. Epub 2009 Feb 6.

39.

Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.

Zhang Z, Hener P, Frossard N, Kato S, Metzger D, Li M, Chambon P.

Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1536-41. doi: 10.1073/pnas.0812668106. Epub 2009 Feb 2.

40.

Allergen-induced lung inflammation in actively sensitized mice assessed with MR imaging.

Blé FX, Cannet C, Zurbruegg S, Karmouty-Quintana H, Bergmann R, Frossard N, Trifilieff A, Beckmann N.

Radiology. 2008 Sep;248(3):834-43. doi: 10.1148/radiol.2482071452. Epub 2008 Jul 22.

PMID:
18647843
41.

Overexpression of functional TrkA receptors after internalisation in human airway smooth muscle cells.

Freund-Michel V, Frossard N.

Biochim Biophys Acta. 2008 Oct;1783(10):1964-71. doi: 10.1016/j.bbamcr.2008.05.014. Epub 2008 Jun 23.

42.

Small neutralizing molecules to inhibit actions of the chemokine CXCL12.

Hachet-Haas M, Balabanian K, Rohmer F, Pons F, Franchet C, Lecat S, Chow KY, Dagher R, Gizzi P, Didier B, Lagane B, Kellenberger E, Bonnet D, Baleux F, Haiech J, Parmentier M, Frossard N, Arenzana-Seisdedos F, Hibert M, Galzi JL.

J Biol Chem. 2008 Aug 22;283(34):23189-99. doi: 10.1074/jbc.M803947200. Epub 2008 Jun 13.

43.

Suppression of allergen-induced airway inflammation and immune response by the peroxisome proliferator-activated receptor-alpha agonist fenofibrate.

Delayre-Orthez C, Becker J, Auwerx J, Frossard N, Pons F.

Eur J Pharmacol. 2008 Feb 26;581(1-2):177-84. Epub 2007 Nov 28.

PMID:
18096152
44.

Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine.

Frossard N, Strolin-Benedetti M, Purohit A, Pauli G.

Br J Clin Pharmacol. 2008 Feb;65(2):172-9. Epub 2007 Oct 29.

45.

The nerve growth factor and its receptors in airway inflammatory diseases.

Freund-Michel V, Frossard N.

Pharmacol Ther. 2008 Jan;117(1):52-76. Epub 2007 Aug 22. Review.

PMID:
17915332
46.

Regulation of peroxisome proliferator-activated receptor-alpha expression during lung inflammation.

Becker J, Delayre-Orthez C, Frossard N, Pons F.

Pulm Pharmacol Ther. 2008;21(2):324-30. Epub 2007 Aug 21.

PMID:
17897854
47.

Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor.

Faisy C, Planquette B, Naline E, Risse PA, Frossard N, Fagon JY, Advenier C, Devillier P.

Life Sci. 2007 Sep 8;81(13):1094-102. Epub 2007 Sep 4.

PMID:
17869310
48.

Role of tachykinin NK3 receptors in the release and effects of nerve growth factor in human isolated bronchi.

Naline E, Höglund CO, Vincent F, Emonds-Alt X, Lagente V, Advenier C, Frossard N.

Eur J Pharmacol. 2007 Apr 10;560(2-3):206-11. Epub 2007 Jan 18.

PMID:
17306250
49.

Anti-proliferative effect of Euphorbia stenoclada in human airway smooth muscle cells in culture.

Chaabi M, Freund-Michel V, Frossard N, Randriantsoa A, Andriantsitohaina R, Lobstein A.

J Ethnopharmacol. 2007 Jan 3;109(1):134-9. Epub 2006 Jul 21.

PMID:
16971077
50.

Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases?

Becker J, Delayre-Orthez C, Frossard N, Pons F.

Fundam Clin Pharmacol. 2006 Oct;20(5):429-47. Review.

PMID:
16968414

Supplemental Content

Loading ...
Support Center