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Items: 8


Discovery of Small-Molecule Antibiotics against a Unique tRNA-Mediated Regulation of Transcription in Gram-Positive Bacteria.

Frohlich KM, Weintraub SF, Bell JT, Todd GC, Väre VYP, Schneider R, Kloos ZA, Tabe ES, Cantara WA, Stark CJ, Onwuanaibe UJ, Duffy BC, Basanta-Sanchez M, Kitchen DB, McDonough KA, Agris PF.

ChemMedChem. 2019 Apr 3;14(7):758-769. doi: 10.1002/cmdc.201800744. Epub 2019 Mar 1.


Multipart Chaperone-Effector Recognition in the Type III Secretion System of Chlamydia trachomatis.

Shen L, Macnaughtan MA, Frohlich KM, Cong Y, Goodwin OY, Chou CW, LeCour L Jr, Krup K, Luo M, Worthylake DK.

J Biol Chem. 2015 Nov 20;290(47):28141-55. doi: 10.1074/jbc.M115.670232. Epub 2015 Oct 5.


Evidence That Antibiotics Bind to Human Mitochondrial Ribosomal RNA Has Implications for Aminoglycoside Toxicity.

Hong S, Harris KA, Fanning KD, Sarachan KL, Frohlich KM, Agris PF.

J Biol Chem. 2015 Jul 31;290(31):19273-86. doi: 10.1074/jbc.M115.655092. Epub 2015 Jun 9.


Andrographolide inhibits intracellular Chlamydia trachomatis multiplication and reduces secretion of proinflammatory mediators produced by human epithelial cells.

Hua Z, Frohlich KM, Zhang Y, Feng X, Zhang J, Shen L.

Pathog Dis. 2015 Feb;73(1):1-11. doi: 10.1093/femspd/ftu022. Epub 2014 Dec 17.


Membrane vesicle production by Chlamydia trachomatis as an adaptive response.

Frohlich KM, Hua Z, Quayle AJ, Wang J, Lewis ME, Chou CW, Luo M, Buckner LR, Shen L.

Front Cell Infect Microbiol. 2014 Jun 10;4:73. doi: 10.3389/fcimb.2014.00073. eCollection 2014. Review.


Altered protein secretion of Chlamydia trachomatis in persistently infected human endocervical epithelial cells.

Wang J, Frohlich KM, Buckner L, Quayle AJ, Luo M, Feng X, Beatty W, Hua Z, Rao X, Lewis ME, Sorrells K, Santiago K, Zhong G, Shen L.

Microbiology. 2011 Oct;157(Pt 10):2759-71. doi: 10.1099/mic.0.044917-0. Epub 2011 Jul 7.


Rickettsia prowazekii uses an sn-glycerol-3-phosphate dehydrogenase and a novel dihydroxyacetone phosphate transport system to supply triose phosphate for phospholipid biosynthesis.

Frohlich KM, Roberts RA, Housley NA, Audia JP.

J Bacteriol. 2010 Sep;192(17):4281-8. doi: 10.1128/JB.00443-10. Epub 2010 Jun 25.

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