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Items: 1 to 50 of 133

1.

Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison.

Walter KM, Dach K, Hayakawa K, Giersiefer S, Heuer H, Lein PJ, Fritsche E.

PLoS One. 2019 Sep 12;14(9):e0221230. doi: 10.1371/journal.pone.0221230. eCollection 2019.

2.

Lower medial thigh perforator (LMTP) propeller flap for reconstruction of soft tissue defects around the knee.

Scaglioni MF, Giunta G, Barth AA, Fritsche E, Arvanitakis M.

Microsurgery. 2019 Aug 7. doi: 10.1002/micr.30499. [Epub ahead of print]

PMID:
31390101
3.

Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity.

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M.

ALTEX. 2019;36(3):506. doi: 10.14573/altex.1904112.

4.

Propeller flap donor site closure by means of another propeller flap: A case report and literature review.

Scaglioni MF, Franchi A, Fritsche E.

Microsurgery. 2019 Jul 18. doi: 10.1002/micr.30497. [Epub ahead of print]

PMID:
31318094
5.

Update of the DevTox data database for harmonized risk assessment and alternative methodologies in developmental toxicology: Report of the 9th Berlin Workshop on Developmental Toxicity.

Solecki R, Rauch M, Gall A, Buschmann J, Kellner R, Kucheryavenko O, Schmitt A, Delrue N, Li W, Hu J, Fujiwara M, Kuwagata M, Mantovani A, Makris SL, Paumgartten F, Schönfelder G, Schneider S, Vogl S, Kleinstreuer N, Schneider M, Schulze F, Fritsche E, Clark R, Shiota K, Chahoud I.

Reprod Toxicol. 2019 Jul 6;89:124-129. doi: 10.1016/j.reprotox.2019.07.003. [Epub ahead of print]

PMID:
31288076
6.

Arsenite interrupts neurodevelopmental processes of human and rat neural progenitor cells: The role of reactive oxygen species and species-specific antioxidative defense.

Masjosthusmann S, Siebert C, Hübenthal U, Bendt F, Baumann J, Fritsche E.

Chemosphere. 2019 Nov;235:447-456. doi: 10.1016/j.chemosphere.2019.06.123. Epub 2019 Jun 17.

PMID:
31272005
7.

Groin defect reconstruction with perforator flaps: Considerations after a retrospective single-center analysis of 54 consecutive cases.

Arvanitakis M, Schlagnitweit P, Franchi A, Fritsche E, Chen YC, Scaglioni MF.

J Plast Reconstr Aesthet Surg. 2019 Jun 8. pii: S1748-6815(19)30260-8. doi: 10.1016/j.bjps.2019.05.052. [Epub ahead of print]

PMID:
31266737
8.

Evaluation of in vitro embryotoxicity tests for Chinese herbal medicines.

Li L, Yin Tang L, Liang B, Wang R, Sun Q, Bik San Lau C, Chung Leung P, Fritsche E, Liebsch M, Seiler Wulczyn AEM, Spielmann H, Wang CC.

Reprod Toxicol. 2019 Jun 20;89:45-53. doi: 10.1016/j.reprotox.2019.06.001. [Epub ahead of print]

PMID:
31228572
9.

Intra-pedicular injection of indocyanine green in flap surgery: A preliminary report.

Franchi A, Fritsche E, Scaglioni MF.

J Plast Reconstr Aesthet Surg. 2019 Aug;72(8):1418-1433. doi: 10.1016/j.bjps.2019.03.027. Epub 2019 Apr 10. No abstract available.

PMID:
30982594
10.

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake.

Hausmann C, Zoschke C, Wolff C, Darvin ME, Sochorová M, Kováčik A, Wanjiku B, Schumacher F, Tigges J, Kleuser B, Lademann J, Fritsche E, Vávrová K, Ma N, Schäfer-Korting M.

Sci Rep. 2019 Feb 27;9(1):2913. doi: 10.1038/s41598-019-39770-6.

11.

[Treatment of a frontotemporal congenital melanocytic nevus combining Integra® with split-thickness skin grafting].

Grufman V, Fritsche E, Hug U.

Handchir Mikrochir Plast Chir. 2018 Dec;50(6):433-434. doi: 10.1055/s-0044-101709. Epub 2019 Jan 8. German. No abstract available.

PMID:
30620980
12.

Comprehensive human stem cell differentiation in a 2D and 3D mode to cardiomyocytes for long-term cultivation and multiparametric monitoring on a multimodal microelectrode array setup.

Fleischer S, Jahnke HG, Fritsche E, Girard M, Robitzki AA.

Biosens Bioelectron. 2019 Feb 1;126:624-631. doi: 10.1016/j.bios.2018.10.061. Epub 2018 Oct 29.

13.

Comparison of migration disturbance potency of epigallocatechin gallate (EGCG) synthetic analogs and EGCG PEGylated PLGA nanoparticles in rat neurospheres.

Kühne BA, Puig T, Ruiz-Martínez S, Crous-Masó J, Planas M, Feliu L, Cano A, García ML, Fritsche E, Llobet JM, Gómez-Catalán J, Barenys M.

Food Chem Toxicol. 2019 Jan;123:195-204. doi: 10.1016/j.fct.2018.10.055. Epub 2018 Oct 25.

PMID:
30367911
14.

[The Conjoined Free Microvascular Arteria Interossea Anterior-Posterior Free Flap - A Case Report].

Engels PE, Wishart KT, Winterholer D, Fritsche E.

Handchir Mikrochir Plast Chir. 2018 Dec;50(6):422-424. doi: 10.1055/a-0621-9282. Epub 2018 Oct 22. German. No abstract available.

PMID:
30347422
15.

Deficiency of the clock gene Bmal1 affects neural progenitor cell migration.

Ali AAH, Schwarz-Herzke B, Mir S, Sahlender B, Victor M, Görg B, Schmuck M, Dach K, Fritsche E, Kremer A, von Gall C.

Brain Struct Funct. 2019 Jan;224(1):373-386. doi: 10.1007/s00429-018-1775-1. Epub 2018 Oct 19.

16.

A Historical Perspective on the Use of Stem/Progenitor Cell-Based In Vitro Methods for Neurodevelopmental Toxicity Testing.

Barenys M, Fritsche E.

Toxicol Sci. 2018 Sep 1;165(1):10-13. doi: 10.1093/toxsci/kfy170. No abstract available.

PMID:
30325470
17.

Corrigendum to "Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing".

Fritsche E, Barenys M, Klose J, Masjosthusmann S, Nimtz L, Schmuck M, Wuttke S, Tigges J.

Toxicol Sci. 2018 Oct 1;165(2):531. doi: 10.1093/toxsci/kfy195. No abstract available.

PMID:
30215788
18.

Editorial: Developmental neurotoxicity.

Bal-Price A, Fritsche E.

Toxicol Appl Pharmacol. 2018 Sep 1;354:1-2. doi: 10.1016/j.taap.2018.07.016. Epub 2018 Jul 17. No abstract available.

PMID:
30030094
19.

Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing.

Fritsche E, Barenys M, Klose J, Masjosthusmann S, Nimtz L, Schmuck M, Wuttke S, Tigges J.

Toxicol Sci. 2018 Sep 1;165(1):21-30. doi: 10.1093/toxsci/kfy178. Review. Erratum in: Toxicol Sci. 2018 Oct 1;165(2):531.

PMID:
29982830
20.

Development of the Concept for Stem Cell-Based Developmental Neurotoxicity Evaluation.

Fritsche E, Barenys M, Klose J, Masjosthusmann S, Nimtz L, Schmuck M, Wuttke S, Tigges J.

Toxicol Sci. 2018 Sep 1;165(1):14-20. doi: 10.1093/toxsci/kfy175. Review.

PMID:
29982725
21.

Microphysiological systems meet hiPSC technology - New tools for disease modeling of liver infections in basic research and drug development.

Raasch M, Fritsche E, Kurtz A, Bauer M, Mosig AS.

Adv Drug Deliv Rev. 2019 Feb 1;140:51-67. doi: 10.1016/j.addr.2018.06.008. Epub 2018 Jun 15. Review.

22.

Culture of human neurospheres in 3D scaffolds for developmental neurotoxicity testing.

Hellwig C, Barenys M, Baumann J, Gassmann K, Casanellas L, Kauer G, Fritsche E.

Toxicol In Vitro. 2018 Oct;52:106-115. doi: 10.1016/j.tiv.2018.06.002. Epub 2018 Jun 5.

PMID:
29883730
23.

A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness.

Masjosthusmann S, Becker D, Petzuch B, Klose J, Siebert C, Deenen R, Barenys M, Baumann J, Dach K, Tigges J, Hübenthal U, Köhrer K, Fritsche E.

Toxicol Appl Pharmacol. 2018 Sep 1;354:40-55. doi: 10.1016/j.taap.2018.05.009. Epub 2018 May 9.

PMID:
29753005
24.

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M.

ALTEX. 2018;35(3):306-352. doi: 10.14573/altex.1712081. Epub 2018 Feb 23. Erratum in: ALTEX. 2019;36(3):506.

25.

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.

Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg HT, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A.

Toxicol Appl Pharmacol. 2018 Sep 1;354:3-6. doi: 10.1016/j.taap.2018.02.004. Epub 2018 Feb 12.

26.

Building a developmental toxicity ontology.

Baker N, Boobis A, Burgoon L, Carney E, Currie R, Fritsche E, Knudsen T, Laffont M, Piersma AH, Poole A, Schneider S, Daston G.

Birth Defects Res. 2018 Apr 3;110(6):502-518. doi: 10.1002/bdr2.1189. Epub 2018 Jan 31. Review.

PMID:
29383852
27.

[The Cyclops Breast as Result after Resection of a Large Recurrence of Breast Cancer - a Rare Case Report].

Wishart KT, Winterholer D, Bogdan I, Fritsche E.

Handchir Mikrochir Plast Chir. 2017 Dec;49(6):405-407. doi: 10.1055/s-0043-119989. Epub 2017 Dec 29. German. No abstract available.

PMID:
29287288
28.

The Vilkki Procedure as an emergency treatment in an apocalyptical hand injury - a case report and first description.

Merky D, Wishart K, Hug U, Fritsche E.

Case Reports Plast Surg Hand Surg. 2017 Nov 15;4(1):96-98. doi: 10.1080/23320885.2017.1403289. eCollection 2017.

29.

Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro.

Hofrichter M, Nimtz L, Tigges J, Kabiri Y, Schröter F, Royer-Pokora B, Hildebrandt B, Schmuck M, Epanchintsev A, Theiss S, Adjaye J, Egly JM, Krutmann J, Fritsche E.

Stem Cell Res. 2017 Dec;25:72-82. doi: 10.1016/j.scr.2017.10.013. Epub 2017 Oct 26.

30.

[Long-term outcome analysis of subjective and objective parameters after breast reduction in 159 cases: Patients judge differently from plastic surgeons].

Osinga R, Babst D, Bodmer ES, Link BC, Fritsche E, Hug U.

Handchir Mikrochir Plast Chir. 2017 Dec;49(6):399-404. doi: 10.1055/s-0043-112747. Epub 2017 Oct 26. German.

PMID:
29076124
31.

Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene.

Potratz S, Jungnickel H, Grabiger S, Tarnow P, Otto W, Fritsche E, von Bergen M, Luch A.

Toxicol Rep. 2016 Sep 16;3:763-773. doi: 10.1016/j.toxrep.2016.09.003. eCollection 2016.

32.

[Defect coverage of the hand using a rare Siamese combined flap].

Pasternak I, Hug U, Rüegg EM, Fritsche E.

Handchir Mikrochir Plast Chir. 2017 Oct;49(5):315-320. doi: 10.1055/s-0042-124614. Epub 2017 Sep 5. German.

PMID:
28873495
33.

OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.

Fritsche E, Crofton KM, Hernandez AF, Hougaard Bennekou S, Leist M, Bal-Price A, Reaves E, Wilks MF, Terron A, Solecki R, Sachana M, Gourmelon A.

ALTEX. 2017;34(2):311-315. doi: 10.14573/altex.1701171. No abstract available.

34.

BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action.

Dach K, Bendt F, Huebenthal U, Giersiefer S, Lein PJ, Heuer H, Fritsche E.

Sci Rep. 2017 Mar 20;7:44861. doi: 10.1038/srep44861.

35.

Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.

Schmuck MR, Temme T, Dach K, de Boer D, Barenys M, Bendt F, Mosig A, Fritsche E.

Arch Toxicol. 2017 Apr;91(4):2017-2028. doi: 10.1007/s00204-016-1852-2. Epub 2016 Oct 8.

PMID:
27722930
36.

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

Aschner M, Ceccatelli S, Daneshian M, Fritsche E, Hasiwa N, Hartung T, Hogberg HT, Leist M, Li A, Mundi WR, Padilla S, Piersma AH, Bal-Price A, Seiler A, Westerink RH, Zimmer B, Lein PJ.

ALTEX. 2017;34(1):49-74. doi: 10.14573/altex.1604201. Epub 2016 Jul 25.

37.

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity.

Bal-Price A, Lein PJ, Keil KP, Sethi S, Shafer T, Barenys M, Fritsche E, Sachana M, Meek MEB.

Neurotoxicology. 2017 Mar;59:240-255. doi: 10.1016/j.neuro.2016.05.010. Epub 2016 May 17. Review.

38.

Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro.

Barenys M, Gassmann K, Baksmeier C, Heinz S, Reverte I, Schmuck M, Temme T, Bendt F, Zschauer TC, Rockel TD, Unfried K, Wätjen W, Sundaram SM, Heuer H, Colomina MT, Fritsche E.

Arch Toxicol. 2017 Feb;91(2):827-837. doi: 10.1007/s00204-016-1709-8. Epub 2016 Apr 26.

PMID:
27116294
39.

[Treatment of an osteo-fascio-cutaneous defect of the femur with a serial connected flow-through free-flap].

Gütler J, Hug U, Link BC, Fritsche E.

Orthopade. 2016 May;45(5):452-5. doi: 10.1007/s00132-016-3236-y. German.

PMID:
26940823
40.

The nuclear aryl hydocarbon receptor is involved in regulation of DNA repair and cell survival following treatment with ionizing radiation.

Dittmann KH, Rothmund MC, Paasch A, Mayer C, Fehrenbacher B, Schaller M, Frauenstein K, Fritsche E, Haarmann-Stemmann T, Braeuning A, Rodemann HP.

Toxicol Lett. 2016 Jan 5;240(1):122-9. doi: 10.1016/j.toxlet.2015.10.017. Epub 2015 Oct 28.

PMID:
26520184
41.

The European Long-range Research Initiative (LRI): A decade of contributions to human health protection, exposure modelling and environmental integrity.

de Boer J, Fritsche E, Schoeters G, Kimber I.

Toxicology. 2015 Nov 4;337:83-90. doi: 10.1016/j.tox.2015.09.003. Epub 2015 Sep 24. Review.

PMID:
26388043
42.

Is Intake of Flavonoid-Based Food Supplements During Pregnancy Safe for the Developing Child? A Literature Review.

Barenys M, Masjosthusmann S, Fritsche E.

Curr Drug Targets. 2017;18(2):196-231. doi: 10.2174/1389450116666150804110049. Review.

PMID:
26240050
43.

Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events.

Baumann J, Gassmann K, Masjosthusmann S, DeBoer D, Bendt F, Giersiefer S, Fritsche E.

Arch Toxicol. 2016 Jun;90(6):1415-27. doi: 10.1007/s00204-015-1568-8. Epub 2015 Jul 28.

PMID:
26216354
44.

[An immobilising malignant phyllodes tumour of the breast].

Fritsche E, Hug U, Winterholer D.

Handchir Mikrochir Plast Chir. 2015 Apr;47(2):142-3. doi: 10.1055/s-0035-1548776. Epub 2015 Apr 2. German.

PMID:
25836949
45.

Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

Waldera Lupa DM, Kalfalah F, Safferling K, Boukamp P, Poschmann G, Volpi E, Götz-Rösch C, Bernerd F, Haag L, Huebenthal U, Fritsche E, Boege F, Grabe N, Tigges J, Stühler K, Krutmann J.

J Invest Dermatol. 2015 Aug;135(8):1954-1968. doi: 10.1038/jid.2015.120. Epub 2015 Mar 27.

46.

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes.

Bal-Price A, Crofton KM, Leist M, Allen S, Arand M, Buetler T, Delrue N, FitzGerald RE, Hartung T, Heinonen T, Hogberg H, Bennekou SH, Lichtensteiger W, Oggier D, Paparella M, Axelstad M, Piersma A, Rached E, Schilter B, Schmuck G, Stoppini L, Tongiorgi E, Tiramani M, Monnet-Tschudi F, Wilks MF, Ylikomi T, Fritsche E.

Arch Toxicol. 2015 Feb;89(2):269-87. doi: 10.1007/s00204-015-1464-2. Epub 2015 Jan 25.

47.

Putative adverse outcome pathways relevant to neurotoxicity.

Bal-Price A, Crofton KM, Sachana M, Shafer TJ, Behl M, Forsby A, Hargreaves A, Landesmann B, Lein PJ, Louisse J, Monnet-Tschudi F, Paini A, Rolaki A, Schrattenholz A, Suñol C, van Thriel C, Whelan M, Fritsche E.

Crit Rev Toxicol. 2015 Jan;45(1):83-91. doi: 10.3109/10408444.2014.981331. Review.

48.

[Long-term outcome after surgical treatment of breast asymmetry: analysis of the patient's perspective in 51 cases].

Osinga R, Bodmer ES, Link BC, Fritsche E, Haug M, Hug U.

Handchir Mikrochir Plast Chir. 2014 Dec;46(6):330-5. doi: 10.1055/s-0034-1394426. Epub 2014 Nov 20. German.

PMID:
25412242
49.

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts.

Waldera-Lupa DM, Kalfalah F, Florea AM, Sass S, Kruse F, Rieder V, Tigges J, Fritsche E, Krutmann J, Busch H, Boerries M, Meyer HE, Boege F, Theis F, Reifenberger G, Stühler K.

Aging (Albany NY). 2014 Oct;6(10):856-78.

50.

miR-23a-3p causes cellular senescence by targeting hyaluronan synthase 2: possible implication for skin aging.

Röck K, Tigges J, Sass S, Schütze A, Florea AM, Fender AC, Theis FJ, Krutmann J, Boege F, Fritsche E, Reifenberger G, Fischer JW.

J Invest Dermatol. 2015 Feb;135(2):369-377. doi: 10.1038/jid.2014.422. Epub 2014 Sep 29.

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