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Items: 28

1.

Defining HLA-II Ligand Processing and Binding Rules with Mass Spectrometry Enhances Cancer Epitope Prediction.

Abelin JG, Harjanto D, Malloy M, Suri P, Colson T, Goulding SP, Creech AL, Serrano LR, Nasir G, Nasrullah Y, McGann CD, Velez D, Ting YS, Poran A, Rothenberg DA, Chhangawala S, Rubinsteyn A, Hammerbacher J, Gaynor RB, Fritsch EF, Greshock J, Oslund RC, Barthelme D, Addona TA, Arieta CM, Rooney MS.

Immunity. 2019 Oct 15;51(4):766-779.e17. doi: 10.1016/j.immuni.2019.08.012. Epub 2019 Sep 5.

PMID:
31495665
2.

Detection of neoantigen-specific T cells following a personalized vaccine in a patient with glioblastoma.

Johanns TM, Miller CA, Liu CJ, Perrin RJ, Bender D, Kobayashi DK, Campian JL, Chicoine MR, Dacey RG, Huang J, Fritsch EF, Gillanders WE, Artyomov MN, Mardis ER, Schreiber RD, Dunn GP.

Oncoimmunology. 2019 Jan 25;8(4):e1561106. doi: 10.1080/2162402X.2018.1561106. eCollection 2019.

3.

Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.

Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA.

Nature. 2019 Jan;565(7738):234-239. doi: 10.1038/s41586-018-0792-9. Epub 2018 Dec 19.

4.

A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression.

Mahoney KM, Shukla SA, Patsoukis N, Chaudhri A, Browne EP, Arazi A, Eisenhaure TM, Pendergraft WF 3rd, Hua P, Pham HC, Bu X, Zhu B, Hacohen N, Fritsch EF, Boussiotis VA, Wu CJ, Freeman GJ.

Cancer Immunol Immunother. 2019 Mar;68(3):421-432. doi: 10.1007/s00262-018-2282-1. Epub 2018 Dec 18.

5.

A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens.

Hu Z, Anandappa AJ, Sun J, Kim J, Leet DE, Bozym DJ, Chen C, Williams L, Shukla SA, Zhang W, Tabbaa D, Steelman S, Olive O, Livak KJ, Kishi H, Muraguchi A, Guleria I, Stevens J, Lane WJ, Burkhardt UE, Fritsch EF, Neuberg D, Ott PA, Keskin DB, Hacohen N, Wu CJ.

Blood. 2018 Nov 1;132(18):1911-1921. doi: 10.1182/blood-2018-04-843763. Epub 2018 Aug 27.

6.

Corrigendum: An immunogenic personal neoantigen vaccine for patients with melanoma.

Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E, Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G, Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ.

Nature. 2018 Mar 14;555(7696):402. doi: 10.1038/nature25145.

7.

An immunogenic personal neoantigen vaccine for patients with melanoma.

Ott PA, Hu Z, Keskin DB, Shukla SA, Sun J, Bozym DJ, Zhang W, Luoma A, Giobbie-Hurder A, Peter L, Chen C, Olive O, Carter TA, Li S, Lieb DJ, Eisenhaure T, Gjini E, Stevens J, Lane WJ, Javeri I, Nellaiappan K, Salazar AM, Daley H, Seaman M, Buchbinder EI, Yoon CH, Harden M, Lennon N, Gabriel S, Rodig SJ, Barouch DH, Aster JC, Getz G, Wucherpfennig K, Neuberg D, Ritz J, Lander ES, Fritsch EF, Hacohen N, Wu CJ.

Nature. 2017 Jul 13;547(7662):217-221. doi: 10.1038/nature22991. Epub 2017 Jul 5. Erratum in: Nature. 2018 Mar 14;555(7696):402.

8.

Immunotherapy advances for glioblastoma.

Reardon DA, Freeman G, Wu C, Chiocca EA, Wucherpfennig KW, Wen PY, Fritsch EF, Curry WT Jr, Sampson JH, Dranoff G.

Neuro Oncol. 2014 Nov;16(11):1441-58. doi: 10.1093/neuonc/nou212. Epub 2014 Sep 4. Review.

9.

Personal neoantigen cancer vaccines: The momentum builds.

Fritsch EF, Hacohen N, Wu CJ.

Oncoimmunology. 2014 Jun 25;3:e29311. eCollection 2014.

10.

HLA-binding properties of tumor neoepitopes in humans.

Fritsch EF, Rajasagi M, Ott PA, Brusic V, Hacohen N, Wu CJ.

Cancer Immunol Res. 2014 Jun;2(6):522-9. doi: 10.1158/2326-6066.CIR-13-0227. Epub 2014 Mar 3. Review.

11.

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia.

Rajasagi M, Shukla SA, Fritsch EF, Keskin DB, DeLuca D, Carmona E, Zhang W, Sougnez C, Cibulskis K, Sidney J, Stevenson K, Ritz J, Neuberg D, Brusic V, Gabriel S, Lander ES, Getz G, Hacohen N, Wu CJ.

Blood. 2014 Jul 17;124(3):453-62. doi: 10.1182/blood-2014-04-567933. Epub 2014 Jun 2.

12.

Vaccines and melanoma.

Ott PA, Fritsch EF, Wu CJ, Dranoff G.

Hematol Oncol Clin North Am. 2014 Jun;28(3):559-69. doi: 10.1016/j.hoc.2014.02.008. Epub 2014 Apr 3. Review.

PMID:
24880947
13.

Getting personal with neoantigen-based therapeutic cancer vaccines.

Hacohen N, Fritsch EF, Carter TA, Lander ES, Wu CJ.

Cancer Immunol Res. 2013 Jul;1(1):11-5. doi: 10.1158/2326-6066.CIR-13-0022. Epub 2013 Apr 7.

14.

The limitations of nucleic acid testing.

Fritsch EF.

Dev Biol Stand. 1994;83:99-105. No abstract available.

PMID:
7883105
15.

Modulation of HBF production by erythropoietin.

Stamatoyannopoulos G, Umemura T, al-Khatti A, Spadaccino E, Abels RI, Fritsch EF, Papayannopoulou T.

Prog Clin Biol Res. 1989;316B:269-80. Review. No abstract available.

PMID:
2482497
16.

Cooperative enhancement of F-cell formation in baboons treated with erythropoietin and hydroxyurea.

Al-Khatti A, Papayannopoulou T, Knitter G, Fritsch EF, Stamatoyannopoulos G.

Blood. 1988 Aug;72(2):817-9.

PMID:
2456801
17.

The thermal stability of oligonucleotide duplexes is sequence independent in tetraalkylammonium salt solutions: application to identifying recombinant DNA clones.

Jacobs KA, Rudersdorf R, Neill SD, Dougherty JP, Brown EL, Fritsch EF.

Nucleic Acids Res. 1988 May 25;16(10):4637-50.

18.

A novel diagnostic method based on DNA strand displacement.

Collins M, Fritsch EF, Ellwood MS, Diamond SE, Williams JI, Brewen JG.

Mol Cell Probes. 1988 Mar;2(1):15-30.

PMID:
2454401
19.

Stimulation of fetal hemoglobin synthesis by erythropoietin in baboons.

Al-Khatti A, Veith RW, Papayannopoulou T, Fritsch EF, Goldwasser E, Stamatoyannopoulos G.

N Engl J Med. 1987 Aug 13;317(7):415-20.

PMID:
2441258
20.

On the induction of fetal hemoglobin in the adult; stress erythropoiesis, cell cycle-specific drugs, and recombinant erythropoietin.

Stamatoyannopoulos G, Veith R, Al-Khatti A, Fritsch EF, Goldwasser E, Papayannopoulou T.

Prog Clin Biol Res. 1987;251:443-53. No abstract available.

PMID:
2448812
21.

Strand displacement applied to assays with nucleic acid probes.

Ellwood MS, Collins M, Fritsch EF, Williams JI, Diamond SE, Brewen JG.

Clin Chem. 1986 Sep;32(9):1631-6.

22.

Isolation and characterization of genomic and cDNA clones of human erythropoietin.

Jacobs K, Shoemaker C, Rudersdorf R, Neill SD, Kaufman RJ, Mufson A, Seehra J, Jones SS, Hewick R, Fritsch EF, et al.

Nature. 1985 Feb 28-Mar 6;313(6005):806-10.

PMID:
3838366
23.

The organization of repetitive sequences in mammalian globin gene clusters.

Fritsch EF, Shen CK, Lawn RM, Maniatis T.

Cold Spring Harb Symp Quant Biol. 1981;45 Pt 2:761-5. No abstract available.

PMID:
6167396
24.

Molecular cloning and characterization of the human beta-like globin gene cluster.

Fritsch EF, Lawn RM, Maniatis T.

Cell. 1980 Apr;19(4):959-72.

PMID:
6155216
25.

The molecular genetics of human hemoglobins.

Maniatis T, Fritsch EF, Lauer J, Lawn RM.

Annu Rev Genet. 1980;14:145-78. Review. No abstract available.

PMID:
6452087
26.

Characterisation of deletions which affect the expression of fetal globin genes in man.

Fritsch EF, Lawn RM, Maniatis T.

Nature. 1979 Jun 14;279(5714):598-603.

PMID:
450109
27.

The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

Lawn RM, Fritsch EF, Parker RC, Blake G, Maniatis T.

Cell. 1978 Dec;15(4):1157-74.

PMID:
728996

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