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Perceptions of the professional and personal impact of hybrid fellowship training: a qualitative study.

MacPherson KL, Shepherd M, Everett JC, Fritsch A, Whitman JM, Dunleavy K.

J Man Manip Ther. 2019 May;27(2):99-108. doi: 10.1080/10669817.2018.1542850. Epub 2018 Nov 22.


Phase II Study of Roniciclib in Combination with Cisplatin/Etoposide or Carboplatin/Etoposide as First-Line Therapy in Patients with Extensive-Disease Small Cell Lung Cancer.

Reck M, Horn L, Novello S, Barlesi F, Albert I, Juhász E, Kowalski D, Robinet G, Cadranel J, Bidoli P, Chung J, Fritsch A, Drews U, Wagner A, Govindan R.

J Thorac Oncol. 2019 Apr;14(4):701-711. doi: 10.1016/j.jtho.2019.01.010. Epub 2019 Jan 21.


Acetylation of intrinsically disordered regions regulates phase separation.

Saito M, Hess D, Eglinger J, Fritsch AW, Kreysing M, Weinert BT, Choudhary C, Matthias P.

Nat Chem Biol. 2019 Jan;15(1):51-61. doi: 10.1038/s41589-018-0180-7. Epub 2018 Dec 10.


Riociguat treatment for portopulmonary hypertension: a subgroup analysis from the PATENT-1/-2 studies.

Cartin-Ceba R, Halank M, Ghofrani HA, Humbert M, Mattson J, Fritsch A, Krowka M.

Pulm Circ. 2018 Apr-Jun;8(2):2045894018769305. doi: 10.1177/2045894018769305. Epub 2018 Mar 22.


Non-invasive perturbations of intracellular flow reveal physical principles of cell organization.

Mittasch M, Gross P, Nestler M, Fritsch AW, Iserman C, Kar M, Munder M, Voigt A, Alberti S, Grill SW, Kreysing M.

Nat Cell Biol. 2018 Mar;20(3):344-351. doi: 10.1038/s41556-017-0032-9. Epub 2018 Feb 5.


Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores.

Grossegesse M, Doellinger J, Fritsch A, Laue M, Piesker J, Schaade L, Nitsche A.

Sci Rep. 2018 Jan 29;8(1):1807. doi: 10.1038/s41598-018-20130-9.


Response to Protocol Review Scenario: Collaborative decision making and navigating the red tape.

Fritsch A.

Lab Anim (NY). 2017 Dec 29;47(1):10-11. doi: 10.1038/laban.1382. No abstract available.


Evaluation and prediction of powder flowability in pharmaceutical tableting.

Hildebrandt C, Gopireddy SR, Fritsch AK, Profitlich T, Scherließ R, Urbanetz NA.

Pharm Dev Technol. 2019 Jan;24(1):35-47. doi: 10.1080/10837450.2017.1412462. Epub 2017 Dec 13.


Matter wave speckle observed in an out-of-equilibrium quantum fluid.

Tavares PES, Fritsch AR, Telles GD, Hussein MS, Impens F, Kaiser R, Bagnato VS.

Proc Natl Acad Sci U S A. 2017 Nov 28;114(48):12691-12695. doi: 10.1073/pnas.1713693114. Epub 2017 Nov 13.


Population Modeling Integrating Pharmacokinetics, Pharmacodynamics, Pharmacogenetics, and Clinical Outcome in Patients With Sunitinib-Treated Cancer.

Diekstra MH, Fritsch A, Kanefendt F, Swen JJ, Moes D, Sörgel F, Kinzig M, Stelzer C, Schindele D, Gauler T, Hauser S, Houtsma D, Roessler M, Moritz B, Mross K, Bergmann L, Oosterwijk E, Kiemeney LA, Guchelaar HJ, Jaehde U.

CPT Pharmacometrics Syst Pharmacol. 2017 Sep;6(9):604-613. doi: 10.1002/psp4.12210. Epub 2017 Jul 13.


Microbiological screenings for infection control in unaccompanied minor refugees: the German Armed Forces Medical Service's experience.

Maaßen W, Wiemer D, Frey C, Kreuzberg C, Tannich E, Hinz R, Wille A, Fritsch A, Hagen RM, Frickmann H.

Mil Med Res. 2017 Apr 21;4:13. doi: 10.1186/s40779-017-0123-8. eCollection 2017.


Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

van der Zanden LFM, Vermeulen SH, Oskarsdottir A, Maurits JSF, Diekstra MHM, Ambert V, Cambon-Thomsen A, Castellano D, Fritsch A, Garcia Donas J, Guarch Troyas R, Guchelaar HJ, Hartmann A, Hulsbergen-van de Kaa C, Jaehde U, Junker K, Martinez-Cardus A, Masson G, Oosterwijk-Wakka J, Radu MT, Rafnar T, Rodriguez-Antona C, Roessler M, Ruijtenbeek R, Stefansson K, Warren A, Wessels L, Eisen T, Kiemeney LALM, Oosterwijk E.

Urol Oncol. 2017 Aug;35(8):529.e9-529.e16. doi: 10.1016/j.urolonc.2017.03.009. Epub 2017 Apr 3.


Comparison of hemodynamic parameters in treatment-naïve and pre-treated patients with pulmonary arterial hypertension in the randomized phase III PATENT-1 study.

Galiè N, Grimminger F, Grünig E, Hoeper MM, Humbert M, Jing ZC, Keogh AM, Langleben D, Rubin LJ, Fritsch A, Davie N, Ghofrani HA.

J Heart Lung Transplant. 2017 May;36(5):509-519. doi: 10.1016/j.healun.2016.12.012. Epub 2016 Dec 24.


Haemodynamic effects of riociguat in inoperable/recurrent chronic thromboembolic pulmonary hypertension.

Kim NH, D'Armini AM, Grimminger F, Grünig E, Hoeper MM, Jansa P, Mayer E, Neurohr C, Simonneau G, Torbicki A, Wang C, Fritsch A, Davie N, Ghofrani HA.

Heart. 2017 Apr;103(8):599-606. doi: 10.1136/heartjnl-2016-309621. Epub 2016 Dec 23.


Spectroscopic and theoretical investigations of phenolic acids in white wines.

Martin C, Bruneel JL, Castet F, Fritsch A, Teissedre PL, Jourdes M, Guillaume F.

Food Chem. 2017 Apr 15;221:568-575. doi: 10.1016/j.foodchem.2016.11.137. Epub 2016 Nov 27.


Predictors of long-term outcomes in patients treated with riociguat for pulmonary arterial hypertension: data from the PATENT-2 open-label, randomised, long-term extension trial.

Ghofrani HA, Grimminger F, Grünig E, Huang Y, Jansa P, Jing ZC, Kilpatrick D, Langleben D, Rosenkranz S, Menezes F, Fritsch A, Nikkho S, Humbert M.

Lancet Respir Med. 2016 May;4(5):361-71. doi: 10.1016/S2213-2600(16)30019-4. Epub 2016 Apr 8.


Predictors of long-term outcomes in patients treated with riociguat for chronic thromboembolic pulmonary hypertension: data from the CHEST-2 open-label, randomised, long-term extension trial.

Simonneau G, D'Armini AM, Ghofrani HA, Grimminger F, Jansa P, Kim NH, Mayer E, Pulido T, Wang C, Colorado P, Fritsch A, Meier C, Nikkho S, Hoeper MM.

Lancet Respir Med. 2016 May;4(5):372-80. doi: 10.1016/S2213-2600(16)30022-4. Epub 2016 Apr 8.


Doripenem Treatment during Continuous Renal Replacement Therapy.

Vossen MG, Wenisch JM, Maier-Salamon A, Fritsch A, Saria K, Zuba C, Jilch S, Lemmerer R, Unger M, Jaehde U, Jäger W, Thalhammer F.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1687-94. doi: 10.1128/AAC.01801-15.


General guidance on exploratory and confirmatory subgroup analysis in late-stage clinical trials.

Dmitrienko A, Muysers C, Fritsch A, Lipkovich I.

J Biopharm Stat. 2016;26(1):71-98. doi: 10.1080/10543406.2015.1092033. Review.


Cannibalism stress response in Bacillus subtilis.

Höfler C, Heckmann J, Fritsch A, Popp P, Gebhard S, Fritz G, Mascher T.

Microbiology. 2016 Jan;162(1):164-76. doi: 10.1099/mic.0.000176. Epub 2015 Sep 11.


Not in the protocol, not approved.

Fritsch A.

Lab Anim (NY). 2015 Aug;44(8):296. doi: 10.1038/laban.823. No abstract available.


Riociguat for pulmonary arterial hypertension associated with congenital heart disease.

Rosenkranz S, Ghofrani HA, Beghetti M, Ivy D, Frey R, Fritsch A, Weimann G, Saleh S, Apitz C.

Heart. 2015 Nov;101(22):1792-9. doi: 10.1136/heartjnl-2015-307832. Epub 2015 Jul 1.


The lensing effect of trapped particles in a dual-beam optical trap.

Grosser S, Fritsch AW, Kiessling TR, Stange R, Käs JA.

Opt Express. 2015 Feb 23;23(4):5221-35. doi: 10.1364/OE.23.005221.


Riociguat for the treatment of pulmonary arterial hypertension: a long-term extension study (PATENT-2).

Rubin LJ, Galiè N, Grimminger F, Grünig E, Humbert M, Jing ZC, Keogh A, Langleben D, Fritsch A, Menezes F, Davie N, Ghofrani HA.

Eur Respir J. 2015 May;45(5):1303-13. doi: 10.1183/09031936.00090614. Epub 2015 Jan 22.


Dose-dependent collagen cross-linking of rabbit scleral tissue by blue light and riboflavin treatment probed by dynamic shear rheology.

Schuldt C, Karl A, Körber N, Koch C, Liu Q, Fritsch AW, Reichenbach A, Wiedemann P, Käs JA, Francke M, Iseli HP.

Acta Ophthalmol. 2015 Aug;93(5):e328-36. doi: 10.1111/aos.12621. Epub 2014 Dec 16.


Riociguat for the treatment of chronic thromboembolic pulmonary hypertension: a long-term extension study (CHEST-2).

Simonneau G, D'Armini AM, Ghofrani HA, Grimminger F, Hoeper MM, Jansa P, Kim NH, Wang C, Wilkins MR, Fritsch A, Davie N, Colorado P, Mayer E.

Eur Respir J. 2015 May;45(5):1293-302. doi: 10.1183/09031936.00087114. Epub 2014 Nov 13.


Active contractions in single suspended epithelial cells.

Gyger M, Stange R, Kießling TR, Fritsch A, Kostelnik KB, Beck-Sickinger AG, Zink M, Käs JA.

Eur Biophys J. 2014 Jan;43(1):11-23. doi: 10.1007/s00249-013-0935-8. Epub 2013 Nov 7.


Keratins significantly contribute to cell stiffness and impact invasive behavior.

Seltmann K, Fritsch AW, Käs JA, Magin TM.

Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18507-12. doi: 10.1073/pnas.1310493110. Epub 2013 Oct 28.


Pharmacokinetics of ganciclovir during continuous venovenous hemodiafiltration in critically ill patients.

Horvatits T, Kitzberger R, Drolz A, Zauner C, Jäger W, Böhmdorfer M, Kraff S, Fritsch A, Thalhammer F, Fuhrmann V, Schenk P.

Antimicrob Agents Chemother. 2014;58(1):94-101. doi: 10.1128/AAC.00892-13. Epub 2013 Oct 21.


Evaluation of single-cell biomechanics as potential marker for oral squamous cell carcinomas: a pilot study.

Runge J, Reichert TE, Fritsch A, Käs J, Bertolini J, Remmerbach TW.

Oral Dis. 2014 Apr;20(3):e120-7. doi: 10.1111/odi.12171. Epub 2013 Sep 6.


Riociguat for the treatment of pulmonary arterial hypertension.

Ghofrani HA, Galiè N, Grimminger F, Grünig E, Humbert M, Jing ZC, Keogh AM, Langleben D, Kilama MO, Fritsch A, Neuser D, Rubin LJ; PATENT-1 Study Group.

N Engl J Med. 2013 Jul 25;369(4):330-40. doi: 10.1056/NEJMoa1209655.


Riociguat for the treatment of chronic thromboembolic pulmonary hypertension.

Ghofrani HA, D'Armini AM, Grimminger F, Hoeper MM, Jansa P, Kim NH, Mayer E, Simonneau G, Wilkins MR, Fritsch A, Neuser D, Weimann G, Wang C; CHEST-1 Study Group.

N Engl J Med. 2013 Jul 25;369(4):319-29. doi: 10.1056/NEJMoa1209657.


Collagen VII plays a dual role in wound healing.

Nyström A, Velati D, Mittapalli VR, Fritsch A, Kern JS, Bruckner-Tuderman L.

J Clin Invest. 2013 Aug;123(8):3498-509. doi: 10.1172/JCI68127. Epub 2013 Jul 8.


Analysis of multiple physical parameters for mechanical phenotyping of living cells.

Kiessling TR, Herrera M, Nnetu KD, Balzer EM, Girvan M, Fritsch AW, Martin SS, Käs JA, Losert W.

Eur Biophys J. 2013 May;42(5):383-94. doi: 10.1007/s00249-013-0888-y. Epub 2013 Mar 17.


Purifying and concentrating genomic DNA from mock forensic samples using Millipore Amicon filters.

Garvin AM, Fritsch A.

J Forensic Sci. 2013 Jan;58 Suppl 1:S173-5. doi: 10.1111/1556-4029.12002. Epub 2012 Oct 19.


[Nonimmune hydrops fetalis: two decades of experience in a university hospital].

Fritsch A, Müller AL, Sanseverino MT, Kessler RG, Barrios PM, Patusco LM, Magalhães JA.

Rev Bras Ginecol Obstet. 2012 Jul;34(7):310-5. Portuguese.


Update on the cardiac safety of moxifloxacin.

Haverkamp W, Kruesmann F, Fritsch A, van Veenhuyzen D, Arvis P.

Curr Drug Saf. 2012 Apr;7(2):149-63.


Tuning liver stiffness against tumours: an in vitro study using entrapped cells in tumour-like microcapsules.

Leal-Egaña A, Fritsch A, Heidebrecht F, Díaz-Cuenca A, Nowicki M, Bader A, Käs J.

J Mech Behav Biomed Mater. 2012 May;9:113-21. doi: 10.1016/j.jmbbm.2012.01.013. Epub 2012 Jan 31.


Antitumoral effects of calcitriol in basal cell carcinomas involve inhibition of hedgehog signaling and induction of vitamin D receptor signaling and differentiation.

Uhmann A, Niemann H, Lammering B, Henkel C, Hess I, Nitzki F, Fritsch A, Prüfer N, Rosenberger A, Dullin C, Schraepler A, Reifenberger J, Schweyer S, Pietsch T, Strutz F, Schulz-Schaeffer W, Hahn H.

Mol Cancer Ther. 2011 Nov;10(11):2179-88. doi: 10.1158/1535-7163.MCT-11-0422. Epub 2011 Aug 30.


Impact of lymph node metastases on serum level of melanoma inhibitory activity in stage III melanoma patients.

Hofmann MA, Schicke B, Fritsch A, Biesold S, Gussmann F, Küchler I, Voit C, Trefzer U.

J Dermatol. 2011 Sep;38(9):880-6. doi: 10.1111/j.1346-8138.2011.01219.x. Epub 2011 Jun 9.


PI3Kβ plays a critical role in neutrophil activation by immune complexes.

Kulkarni S, Sitaru C, Jakus Z, Anderson KE, Damoulakis G, Davidson K, Hirose M, Juss J, Oxley D, Chessa TA, Ramadani F, Guillou H, Segonds-Pichon A, Fritsch A, Jarvis GE, Okkenhaug K, Ludwig R, Zillikens D, Mocsai A, Vanhaesebroeck B, Stephens LR, Hawkins PT.

Sci Signal. 2011 Apr 12;4(168):ra23. doi: 10.1126/scisignal.2001617.


Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefanova I, Milh M, Kortüm F, Fritsch A, Pientka FK, Hellenbroich Y, Kalscheuer VM, Kohlhase J, Moog U, Rappold G, Rauch A, Ropers HH, von Spiczak S, Tönnies H, Villeneuve N, Villard L, Zabel B, Zenker M, Laube B, Reis A, Wieczorek D, Van Maldergem L, Kutsche K.

Nat Genet. 2010 Nov;42(11):1021-6. doi: 10.1038/ng.677. Epub 2010 Oct 3.


Experimental poromechanics of trabecular bone strength: role of Terzaghi's effective stress and of tissue level stress fluctuations.

Brynk T, Hellmich C, Fritsch A, Zysset P, Eberhardsteiner J.

J Biomech. 2011 Feb 3;44(3):501-8. doi: 10.1016/j.jbiomech.2010.09.016. Epub 2010 Sep 29.


Metal sensitization precipitates skin blistering in epidermolysis bullosa acquisita.

Baican A, Chiriac G, Baican C, Macovei V, Ciuce D, Fritsch A, Sitaru C.

J Dermatol. 2010 Mar;37(3):280-2. doi: 10.1111/j.1346-8138.2010.00810.x. No abstract available.


The role of disc-type crystal shape for micromechanical predictions of elasticity and strength of hydroxyapatite biomaterials.

Fritsch A, Hellmich C, Dormieux L.

Philos Trans A Math Phys Eng Sci. 2010 Apr 28;368(1917):1913-35. doi: 10.1098/rsta.2010.0005.


Cross-reactivity of autoantibodies from patients with epidermolysis bullosa acquisita with murine collagen VII.

Csorba K, Sesarman A, Oswald E, Feldrihan V, Fritsch A, Hashimoto T, Sitaru C.

Cell Mol Life Sci. 2010 Apr;67(8):1343-51. doi: 10.1007/s00018-009-0256-3. Epub 2010 Jan 20.


Dominant-negative effects of COL7A1 mutations can be rescued by controlled overexpression of normal collagen VII.

Fritsch A, Spassov S, Elfert S, Schlosser A, Gache Y, Meneguzzi G, Bruckner-Tuderman L.

J Biol Chem. 2009 Oct 30;284(44):30248-56. doi: 10.1074/jbc.M109.045294. Epub 2009 Sep 2.


A case of epidermolysis bullosa acquisita with clinical features of Brunsting-Perry pemphigoid showing an excellent response to colchicine.

Tanaka N, Dainichi T, Ohyama B, Yasumoto S, Oono T, Iwatsuki K, Elfert S, Fritsch A, Bruckner-Tuderman L, Hashimoto T.

J Am Acad Dermatol. 2009 Oct;61(4):715-9. doi: 10.1016/j.jaad.2008.12.020. Epub 2009 Aug 13.


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