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Items: 1 to 50 of 70

1.

Flow disturbances and progression of endocardial fibroelastosis - a case report.

Weixler V, Hammer PE, Marx GR, Emani SM, Del Nido PJ, Friehs I.

Cardiovasc Pathol. 2019 May 3;42:1-3. doi: 10.1016/j.carpath.2019.04.004. [Epub ahead of print]

PMID:
31150840
2.

Alloreactivity and allorecognition of syngeneic and allogeneic mitochondria.

Ramirez-Barbieri G, Moskowitzova K, Shin B, Blitzer D, Orfany A, Guariento A, Iken K, Friehs I, Zurakowski D, Del Nido PJ, McCully JD.

Mitochondrion. 2019 May;46:103-115. doi: 10.1016/j.mito.2018.03.002. Epub 2018 Mar 26.

PMID:
29588218
3.

Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation.

Wendell DC, Friehs I, Samyn MM, Harmann LM, LaDisa JF Jr.

J Surg Res. 2017 Oct;218:194-201. doi: 10.1016/j.jss.2017.05.053. Epub 2017 Jun 19.

4.

Vascular Endothelial Growth Factor Prevents Endothelial-to-Mesenchymal Transition in Hypertrophy.

Illigens BM, Casar Berazaluce A, Poutias D, Gasser R, Del Nido PJ, Friehs I.

Ann Thorac Surg. 2017 Sep;104(3):932-939. doi: 10.1016/j.athoracsur.2017.01.112. Epub 2017 May 5.

5.

A Growth-Accommodating Implant for Paediatric Applications.

Feins EN, Lee Y, O'Cearbhaill ED, Vasilyev NV, Shimada S, Friehs I, Perrin D, Hammer PE, Yamauchi H, Marx G, Gosline A, Arabagi V, Karp JM, Del Nido PJ.

Nat Biomed Eng. 2017;1:818-825. doi: 10.1038/s41551-017-0142-5. Epub 2017 Oct 10.

6.

Myocardial rescue with autologous mitochondrial transplantation in a porcine model of ischemia/reperfusion.

Kaza AK, Wamala I, Friehs I, Kuebler JD, Rathod RH, Berra I, Ericsson M, Yao R, Thedsanamoorthy JK, Zurakowski D, Levitsky S, Del Nido PJ, Cowan DB, McCully JD.

J Thorac Cardiovasc Surg. 2017 Apr;153(4):934-943. doi: 10.1016/j.jtcvs.2016.10.077. Epub 2016 Nov 15.

7.

Development of a Vascularized Heterotopic Neonatal Rat Heart Transplantation Model.

Shimada S, Del Nido PJ, Friehs I.

Eur Surg Res. 2016;57(3-4):240-251. Epub 2016 Aug 20.

PMID:
27544776
8.

Pilomotor function is impaired in patients with Parkinson's disease: A study of the adrenergic axon-reflex response and autonomic functions.

Siepmann T, Frenz E, Penzlin AI, Goelz S, Zago W, Friehs I, Kubasch ML, Wienecke M, Löhle M, Schrempf W, Barlinn K, Siegert J, Storch A, Reichmann H, Illigens BM.

Parkinsonism Relat Disord. 2016 Oct;31:129-134. doi: 10.1016/j.parkreldis.2016.08.001. Epub 2016 Aug 11.

PMID:
27569843
9.

Intracoronary Delivery of Mitochondria to the Ischemic Heart for Cardioprotection.

Cowan DB, Yao R, Akurathi V, Snay ER, Thedsanamoorthy JK, Zurakowski D, Ericsson M, Friehs I, Wu Y, Levitsky S, Del Nido PJ, Packard AB, McCully JD.

PLoS One. 2016 Aug 8;11(8):e0160889. doi: 10.1371/journal.pone.0160889. eCollection 2016.

10.

A light-reflecting balloon catheter for atraumatic tissue defect repair.

Roche ET, Fabozzo A, Lee Y, Polygerinos P, Friehs I, Schuster L, Whyte W, Casar Berazaluce AM, Bueno A, Lang N, Pereira MJ, Feins E, Wasserman S, O'Cearbhaill ED, Vasilyev NV, Mooney DJ, Karp JM, Del Nido PJ, Walsh CJ.

Sci Transl Med. 2015 Sep 23;7(306):306ra149. doi: 10.1126/scitranslmed.aaa2406. Epub 2015 Sep 23.

PMID:
26400910
11.
12.

Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition.

Xu X, Friehs I, Zhong Hu T, Melnychenko I, Tampe B, Alnour F, Iascone M, Kalluri R, Zeisberg M, Del Nido PJ, Zeisberg EM.

Circ Res. 2015 Feb 27;116(5):857-66. doi: 10.1161/CIRCRESAHA.116.305629. Epub 2015 Jan 13.

13.

Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death.

Yoshida T, Friehs I, Mummidi S, del Nido PJ, Addulnour-Nakhoul S, Delafontaine P, Valente AJ, Chandrasekar B.

J Mol Cell Cardiol. 2014 Oct;75:141-51. doi: 10.1016/j.yjmcc.2014.07.007. Epub 2014 Aug 7.

14.

A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects.

Lang N, Pereira MJ, Lee Y, Friehs I, Vasilyev NV, Feins EN, Ablasser K, O'Cearbhaill ED, Xu C, Fabozzo A, Padera R, Wasserman S, Freudenthal F, Ferreira LS, Langer R, Karp JM, del Nido PJ.

Sci Transl Med. 2014 Jan 8;6(218):218ra6. doi: 10.1126/scitranslmed.3006557.

15.

Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium.

Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JD.

Am J Physiol Heart Circ Physiol. 2013 Mar 1;304(5):H697-708. doi: 10.1152/ajpheart.00802.2012. Epub 2012 Dec 21.

16.

A highly tunable biocompatible and multifunctional biodegradable elastomer.

Pereira MJ, Ouyang B, Sundback CA, Lang N, Friehs I, Mureli S, Pomerantseva I, McFadden J, Mochel MC, Mwizerwa O, Del Nido P, Sarkar D, Masiakos PT, Langer R, Ferreira LS, Karp JM.

Adv Mater. 2013 Feb 25;25(8):1209-15. doi: 10.1002/adma.201203824. Epub 2012 Dec 12. No abstract available.

17.

An animal model of endocardial fibroelastosis.

Friehs I, Illigens B, Melnychenko I, Zhong-Hu T, Zeisberg E, Del Nido PJ.

J Surg Res. 2013 Jun 1;182(1):94-100. doi: 10.1016/j.jss.2012.07.069. Epub 2012 Aug 17.

18.

Endogenous angiogenesis inhibitors prevent adaptive capillary growth in left ventricular pressure overload hypertrophy.

Nikolova A, Ablasser K, Wyler von Ballmoos MC, Poutias D, Kaza E, McGowan FX, Moses MA, Del Nido PJ, Friehs I.

Ann Thorac Surg. 2012 Nov;94(5):1509-17. doi: 10.1016/j.athoracsur.2012.05.052. Epub 2012 Jul 12.

19.

No effect of short-term hypertension on bone matrix mineralization in a surgical animal model in immature rabbits.

Hofstaetter JG, Blouin S, Friehs I, Klaushofer K, Roschger P.

Clin Exp Hypertens. 2012;34(2):107-12. doi: 10.3109/10641963.2011.601382. Epub 2011 Oct 3.

PMID:
21967032
20.

Up-regulation of soluble vascular endothelial growth factor receptor-1 prevents angiogenesis in hypertrophied myocardium.

Kaza E, Ablasser K, Poutias D, Griffiths ER, Saad FA, Hofstaetter JG, del Nido PJ, Friehs I.

Cardiovasc Res. 2011 Feb 1;89(2):410-8. doi: 10.1093/cvr/cvq321. Epub 2010 Oct 8.

21.

Electron transport chain dysfunction in neonatal pressure-overload hypertrophy precedes cardiomyocyte apoptosis independent of oxidative stress.

Griffiths ER, Friehs I, Scherr E, Poutias D, McGowan FX, Del Nido PJ.

J Thorac Cardiovasc Surg. 2010 Jun;139(6):1609-17. doi: 10.1016/j.jtcvs.2009.08.060. Epub 2009 Dec 28.

22.

Development of left ventricular diastolic dysfunction with preservation of ejection fraction during progression of infant right ventricular hypertrophy.

Kitahori K, He H, Kawata M, Cowan DB, Friehs I, Del Nido PJ, McGowan FX Jr.

Circ Heart Fail. 2009 Nov;2(6):599-607. doi: 10.1161/CIRCHEARTFAILURE.109.862664. Epub 2009 Sep 24.

23.

Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium.

Choi YH, Cowan DB, Moran AM, Colan SD, Stamm C, Takeuchi K, Friehs I, del Nido PJ, McGowan FX Jr.

J Thorac Cardiovasc Surg. 2009 Jun;137(6):1356-62, 1362.e1-3. doi: 10.1016/j.jtcvs.2008.12.020. Epub 2009 Mar 17.

24.

Proteasome inhibition in hypertrophied myocardium.

Friehs I.

Am J Physiol Heart Circ Physiol. 2008 Oct;295(4):H1373-4. doi: 10.1152/ajpheart.00886.2008. Epub 2008 Aug 15. No abstract available.

25.

Inhibition of glycogen synthase kinase-3beta improves tolerance to ischemia in hypertrophied hearts.

Barillas R, Friehs I, Cao-Danh H, Martinez JF, del Nido PJ.

Ann Thorac Surg. 2007 Jul;84(1):126-33.

26.

Age-dependent expression of VEGF isoforms and receptors in the rabbit anterior cruciate ligament.

Hofstaetter JG, Saad FA, Sunk IG, Bobacz K, Friehs I, Glimcher MJ.

Biochim Biophys Acta. 2007 Jul;1770(7):997-1002. Epub 2007 Feb 27.

PMID:
17459591
27.

Dopamine induces postischemic cardiomyocyte apoptosis in vivo: an effect ameliorated by propofol.

Roy N, Friehs I, Cowan DB, Zurakowski D, McGowan FX, del Nido PJ.

Ann Thorac Surg. 2006 Dec;82(6):2192-9.

PMID:
17126134
28.

Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart.

Friehs I, Barillas R, Vasilyev NV, Roy N, McGowan FX, del Nido PJ.

Circulation. 2006 Jul 4;114(1 Suppl):I290-5.

29.

Cardiac conduction through engineered tissue.

Choi YH, Stamm C, Hammer PE, Kwaku KF, Marler JJ, Friehs I, Jones M, Rader CM, Roy N, Eddy MT, Triedman JK, Walsh EP, McGowan FX Jr, del Nido PJ, Cowan DB.

Am J Pathol. 2006 Jul;169(1):72-85.

30.

Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis.

Friehs I, Margossian RE, Moran AM, Cao-Danh H, Moses MA, del Nido PJ.

Basic Res Cardiol. 2006 May;101(3):204-13. Epub 2005 Dec 23.

31.

Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart.

Nathan M, Friehs I, Choi YH, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ.

Ann Thorac Surg. 2005 May;79(5):1620-6.

PMID:
15854943
32.

Impaired insulin-signaling in hypertrophied hearts contributes to ischemic injury.

Friehs I, Cao-Danh H, Nathan M, McGowan FX, del Nido PJ.

Biochem Biophys Res Commun. 2005 May 27;331(1):15-22.

33.

Promoting angiogenesis protects severely hypertrophied hearts from ischemic injury.

Friehs I, Moran AM, Stamm C, Choi YH, Cowan DB, McGowan FX, del Nido PJ.

Ann Thorac Surg. 2004 Jun;77(6):2004-10; discussion 2011.

PMID:
15172254
34.

Cytosolic calcium in the ischemic rabbit heart: assessment by pH- and temperature-adjusted rhod-2 spectrofluorometry.

Stamm C, Friehs I, Choi YH, Zurakowski D, McGowan FX, del Nido PJ.

Cardiovasc Res. 2003 Sep 1;59(3):695-704.

PMID:
14499871
35.

Postnatal increase in insulin-sensitive glucose transporter expression is associated with improved recovery of postischemic myocardial function.

Friehs I, Cao-Danh H, Stamm C, Cowan DB, McGowan FX, del Nido PJ.

J Thorac Cardiovasc Surg. 2003 Jul;126(1):263-71.

36.

Improving results of the modified Fontan operation in patients with heterotaxy syndrome.

Stamm C, Friehs I, Duebener LF, Zurakowski D, Mayer JE Jr, Jonas RA, del Nido PJ.

Ann Thorac Surg. 2002 Dec;74(6):1967-77; discussion 1978.

PMID:
12643382
37.

Noninvasive serial evaluation of myocardial mechanics in pressure overload hypertrophy of rabbit myocardium.

Moran AM, Friehs I, Takeuchi K, Stamm C, Hammer PE, McGowan FX, del Nido PJ, Colan SD.

Herz. 2003 Feb;28(1):52-62.

PMID:
12616321
38.

Increased susceptibility of hypertrophied hearts to ischemic injury.

Friehs I, del Nido PJ.

Ann Thorac Surg. 2003 Feb;75(2):S678-84. Review.

PMID:
12607712
39.

Dopamine treatment of postischemic contractile dysfunction rapidly induces calcium-dependent pro-apoptotic signaling.

Stamm C, Friehs I, Cowan DB, Cao-Danh H, Choi YH, Duebener LF, McGowan FX, del Nido PJ.

Circulation. 2002 Sep 24;106(12 Suppl 1):I290-8.

PMID:
12354748
40.

Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C.

Munakata M, Stamm C, Friehs I, Zurakowski D, Cowan DB, Cao-Danh H, McGowan FX Jr, del Nido PJ.

Ann Thorac Surg. 2002 Apr;73(4):1236-45.

PMID:
11998814
41.

Outcome after reconstruction of discontinuous pulmonary arteries.

Stamm C, Friehs I, Zurakowski D, Scheule AM, Moran AM, Lock JE, Mayer JE Jr, del Nido PJ, Jonas RA.

J Thorac Cardiovasc Surg. 2002 Feb;123(2):246-57.

42.

Rapid endotoxin-induced alterations in myocardial calcium handling: obligatory role of cardiac TNF-alpha.

Stamm C, Cowan DB, Friehs I, Noria S, del Nido PJ, McGowan FX Jr.

Anesthesiology. 2001 Dec;95(6):1396-405.

PMID:
11748398
43.

Insulin-like growth factor-1 improves postischemic recovery in hypertrophied hearts.

Friehs I, Stamm C, Cao-Danh H, McGowan FX, del Nido PJ.

Ann Thorac Surg. 2001 Nov;72(5):1650-6.

PMID:
11722060
44.

Inhibition of tumor necrosis factor-alpha improves postischemic recovery of hypertrophied hearts.

Stamm C, Friehs I, Cowan DB, Moran AM, Cao-Danh H, Duebener LF, del Nido PJ, McGowan FX Jr.

Circulation. 2001 Sep 18;104(12 Suppl 1):I350-5.

PMID:
11568081
45.

Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity.

Stamm C, Friehs I, Cowan DB, Cao-Danh H, Noria S, Munakata M, McGowan FX Jr, del Nido PJ.

Cardiovasc Res. 2001 Jul;51(1):108-21.

PMID:
11399253
46.

Congenital supravalvar aortic stenosis: a simple lesion?

Stamm C, Friehs I, Ho SY, Moran AM, Jonas RA, del Nido PJ.

Eur J Cardiothorac Surg. 2001 Feb;19(2):195-202. Review.

PMID:
11167112
47.

Long-term results of the lateral tunnel Fontan operation.

Stamm C, Friehs I, Mayer JE Jr, Zurakowski D, Triedman JK, Moran AM, Walsh EP, Lock JE, Jonas RA, Del Nido PJ.

J Thorac Cardiovasc Surg. 2001 Jan;121(1):28-41.

48.

Differential role of sarcolemmal and mitochondrial K(ATP) channels in adenosine-enhanced ischemic preconditioning.

Toyoda Y, Friehs I, Parker RA, Levitsky S, McCully JD.

Am J Physiol Heart Circ Physiol. 2000 Dec;279(6):H2694-703.

49.

Surgery for bilateral outflow tract obstruction in elastin arteriopathy.

Stamm C, Friehs I, Moran AM, Zurakowski D, Bacha E, Mayer JE, Jonas RA, Del Nido PJ.

J Thorac Cardiovasc Surg. 2000 Oct;120(4):755-63.

50.

Impaired glucose transporter activity in pressure-overload hypertrophy is an early indicator of progression to failure.

Friehs I, Moran AM, Stamm C, Colan SD, Takeuchi K, Cao-Danh H, Rader CM, McGowan FX, del Nido PJ.

Circulation. 1999 Nov 9;100(19 Suppl):II187-93.

PMID:
10567302

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