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Items: 11

1.

Quantifying Target Occupancy of Small Molecules Within Living Cells.

Robers MB, Friedman-Ohana R, Huber K, Kilpatrick L, Vasta JD, Berger BT, Chaudhry C, Hill S, Müller S, Knapp S, Wood KV.

Annu Rev Biochem. 2020 Mar 24. doi: 10.1146/annurev-biochem-011420-092302. [Epub ahead of print]

PMID:
32208767
2.

The luminescent HiBiT peptide enables selective quantitation of GPCR ligand engagement and internalization in living cells.

Boursier ME, Levin S, Zimmerman K, Machleidt T, Hurst R, Butler BL, Eggers CT, Kirkland TA, Wood KV, Friedman Ohana R.

J Biol Chem. 2020 Feb 27. pii: jbc.RA119.011952. doi: 10.1074/jbc.RA119.011952. [Epub ahead of print]

3.

Utilizing a Simple Method for Stoichiometric Protein Labeling to Quantify Antibody Blockade.

Friedman Ohana R, Hurst R, Rosenblatt M, Levin S, Machleidt T, Kirkland TA, Encell LP, Robers MB, Wood KV.

Sci Rep. 2019 May 7;9(1):7046. doi: 10.1038/s41598-019-43469-z.

4.

Real-Time Ligand Binding of Fluorescent VEGF-A Isoforms that Discriminate between VEGFR2 and NRP1 in Living Cells.

Peach CJ, Kilpatrick LE, Friedman-Ohana R, Zimmerman K, Robers MB, Wood KV, Woolard J, Hill SJ.

Cell Chem Biol. 2018 Oct 18;25(10):1208-1218.e5. doi: 10.1016/j.chembiol.2018.06.012. Epub 2018 Jul 26.

5.

Target Identification Using Cell Permeable and Cleavable Chloroalkane Derivatized Small Molecules.

Mendez-Johnson JL, Daniels DL, Urh M, Friedman Ohana R.

Methods Mol Biol. 2017;1647:91-108. doi: 10.1007/978-1-4939-7201-2_6.

PMID:
28808997
6.

Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes.

Kilpatrick LE, Friedman-Ohana R, Alcobia DC, Riching K, Peach CJ, Wheal AJ, Briddon SJ, Robers MB, Zimmerman K, Machleidt T, Wood KV, Woolard J, Hill SJ.

Biochem Pharmacol. 2017 Jul 15;136:62-75. doi: 10.1016/j.bcp.2017.04.006. Epub 2017 Apr 7.

7.

Improved Deconvolution of Protein Targets for Bioactive Compounds Using a Palladium Cleavable Chloroalkane Capture Tag.

Friedman Ohana R, Levin S, Wood MG, Zimmerman K, Dart ML, Schwinn MK, Kirkland TA, Hurst R, Uyeda HT, Encell LP, Wood KV.

ACS Chem Biol. 2016 Sep 16;11(9):2608-17. doi: 10.1021/acschembio.6b00408. Epub 2016 Aug 3.

8.

Development of a dehalogenase-based protein fusion tag capable of rapid, selective and covalent attachment to customizable ligands.

Encell LP, Friedman Ohana R, Zimmerman K, Otto P, Vidugiris G, Wood MG, Los GV, McDougall MG, Zimprich C, Karassina N, Learish RD, Hurst R, Hartnett J, Wheeler S, Stecha P, English J, Zhao K, Mendez J, Benink HA, Murphy N, Daniels DL, Slater MR, Urh M, Darzins A, Klaubert DH, Bulleit RF, Wood KV.

Curr Chem Genomics. 2012;6:55-71. doi: 10.2174/1875397301206010055. Epub 2012 Oct 5.

9.

A RecG-independent nonconservative branch migration mechanism in Escherichia coli recombination.

Friedman-Ohana R, Karunker I, Cohen A.

J Bacteriol. 1999 Dec;181(23):7199-205.

10.
11.

Chi-dependent intramolecular recombination in Escherichia coli.

Friedman-Ohana R, Karunker I, Cohen A.

Genetics. 1998 Feb;148(2):545-57.

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