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Items: 1 to 50 of 264

1.

Genes Implicated in Rare Congenital Inner Ear and Cochleovestibular Nerve Malformations.

Kari E, Llaci L, Go JL, Naymik M, Knowles JA, Leal SM, Rangasamy S, Huentelman MJ, Liang W, Friedman RA, Schrauwen I.

Ear Hear. 2020 Jan 24. doi: 10.1097/AUD.0000000000000819. [Epub ahead of print]

PMID:
31985533
2.

Targeting MEK5 impairs nonhomologous end-joining repair and sensitizes prostate cancer to DNA damaging agents.

Broustas CG, Duval AJ, Chaudhary KR, Friedman RA, Virk RK, Lieberman HB.

Oncogene. 2020 Jan 24. doi: 10.1038/s41388-020-1163-1. [Epub ahead of print]

PMID:
31980741
3.

Meeting the challenges of medical student mental health and well-being today.

Choi AMK, Moon JE, Friedman RA.

Med Educ. 2020 Mar;54(3):183-185. doi: 10.1111/medu.14064. No abstract available.

PMID:
31958172
4.

The Direct Costs of Microsurgical Resection of Vestibular Schwannomas.

Saliba J, Mohammadzadeh A, Tawfik KO, Carriere JS, Schwartz MS, Nguyen QT, Friedman RA.

Otol Neurotol. 2020 Mar;41(3):397-402. doi: 10.1097/MAO.0000000000002546.

PMID:
31868780
5.

A de novo SIX1 variant in a patient with a rare nonsyndromic cochleovestibular nerve abnormality, cochlear hypoplasia, and bilateral sensorineural hearing loss.

Kari E, Llaci L, Go JL, Naymik M, Knowles JA, Leal SM, Rangasamy S, Huentelman MJ, Friedman RA, Schrauwen I.

Mol Genet Genomic Med. 2019 Dec;7(12):e995. doi: 10.1002/mgg3.995. Epub 2019 Oct 8.

6.

A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis.

Hurtado Del Pozo C, Ruiz HH, Arivazhagan L, Aranda JF, Shim C, Daya P, Derk J, MacLean M, He M, Frye L, Friedline RH, Noh HL, Kim JK, Friedman RA, Ramasamy R, Schmidt AM.

Cell Rep. 2019 Jul 16;28(3):773-791.e7. doi: 10.1016/j.celrep.2019.06.061.

7.

Tophaceous Gout of the Middle Ear: Case Reports and Review of the Literature.

Saliba J, Sakano H, Friedman RA, Harris JP.

Audiol Neurootol. 2019;24(2):51-55. doi: 10.1159/000500514. Epub 2019 Jun 5. Review.

8.

The α2 chain of type IX collagen is essential for type IX collagen biosynthesis.

Balasubramanian K, Weis M, Eyre DR, Martin J, Ortiz-Sanchez J, Duran I, Vangala S, Wang J, Friedman RA, Krakow D, Cohn DH.

Am J Med Genet A. 2019 Aug;179(8):1672-1677. doi: 10.1002/ajmg.a.61208. Epub 2019 Jun 3. No abstract available.

PMID:
31161720
9.

High-resolution genomic alterations in Barrett's metaplasia of patients who progress to esophageal dysplasia and adenocarcinoma.

Sepulveda JL, Komissarova EV, Kongkarnka S, Friedman RA, Davison JM, Levy B, Bryk D, Jobanputra V, Del Portillo A, Falk GW, Sonett JR, Lightdale CJ, Abrams JA, Wang TC, Sepulveda AR.

Int J Cancer. 2019 Nov 15;145(10):2754-2766. doi: 10.1002/ijc.32351. Epub 2019 May 2.

PMID:
31001805
10.

Advances in understanding of presbycusis.

Tawfik KO, Klepper K, Saliba J, Friedman RA.

J Neurosci Res. 2019 Apr 4. doi: 10.1002/jnr.24426. [Epub ahead of print] Review.

PMID:
30950547
11.

HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.

Hernandez C, Huebener P, Pradere JP, Antoine DJ, Friedman RA, Schwabe RF.

J Clin Invest. 2019 Apr 1;129(4):1803. doi: 10.1172/JCI128262. Epub 2019 Apr 1. No abstract available.

12.

HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.

Hernandez C, Huebener P, Pradere JP, Antoine DJ, Friedman RA, Schwabe RF.

J Clin Invest. 2019 Apr 1;129(4):1803. doi: 10.1172/JCI128261. Epub 2019 Apr 1. No abstract available.

13.

Hearing Preservation in Vestibular Schwannoma Surgery.

Saliba J, Friedman RA, Cueva RA.

J Neurol Surg B Skull Base. 2019 Apr;80(2):149-155. doi: 10.1055/s-0038-1677550. Epub 2019 Jan 10.

PMID:
30931222
14.

Cochlear FLAIR Signal Changes in Hearing Preservation Vestibular Schwannoma Surgery.

Tu NC, Bobarnac Dogaru G, Huang P, Kim J, Diegnan B, Go JL, Friedman RA.

Otol Neurotol. 2019 Mar;40(3):375-383. doi: 10.1097/MAO.0000000000002102.

PMID:
30664035
15.

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.

Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC.

Cancer Cell. 2018 Nov 12;34(5):863-867. doi: 10.1016/j.ccell.2018.10.010. No abstract available.

16.

The receptor for advanced glycation end products (RAGE) and DIAPH1: unique mechanisms and healing the wounded vascular system.

Ramasamy R, Friedman RA, Shekhtman A, Schmidt AM.

Expert Rev Proteomics. 2019 Jun;16(6):471-474. doi: 10.1080/14789450.2018.1536551. Epub 2019 Jan 13. No abstract available.

PMID:
30324836
17.

Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.

Renz BW, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, Middelhoff MA, Ilmer M, Oberstein PE, Angele MK, Deng H, Hayakawa Y, Westphalen CB, Werner J, Remotti H, Reichert M, Tailor YH, Nagar K, Friedman RA, Iuga AC, Olive KP, Wang TC.

Cancer Discov. 2018 Nov;8(11):1458-1473. doi: 10.1158/2159-8290.CD-18-0046. Epub 2018 Sep 5.

18.

Deletion of the formin Diaph1 protects from structural and functional abnormalities in the murine diabetic kidney.

Manigrasso MB, Friedman RA, Ramasamy R, D'Agati V, Schmidt AM.

Am J Physiol Renal Physiol. 2018 Dec 1;315(6):F1601-F1612. doi: 10.1152/ajprenal.00075.2018. Epub 2018 Aug 22.

19.

Prostate cancer: unmet clinical needs and RAD9 as a candidate biomarker for patient management.

Lieberman HB, Rai AJ, Friedman RA, Hopkins KM, Broustas CG.

Transl Cancer Res. 2018 Jul;7(Suppl 6):S651-S661. doi: 10.21037/tcr.2018.01.21. Epub 2018 Jan 14.

20.

Profiling of Stem/Progenitor Cell Regulatory Genes of the Synovial Joint by Genome-Wide RNA-Seq Analysis.

Zhou Y, Chen M, Ricupero CL, He L, Wu J, Chen K, Friedman RA, Guarnieri P, Wang Z, Zhou X, Mao JJ.

Biomed Res Int. 2018 Jun 26;2018:9327487. doi: 10.1155/2018/9327487. eCollection 2018.

21.

Overcoming Tribalism.

Friedman RA.

Psychiatr Serv. 2018 Sep 1;69(9):946-947. doi: 10.1176/appi.ps.201800259. Epub 2018 Jul 26. No abstract available.

PMID:
30045662
22.

De novo variants in GREB1L are associated with non-syndromic inner ear malformations and deafness.

Schrauwen I, Kari E, Mattox J, Llaci L, Smeeton J, Naymik M, Raible DW, Knowles JA, Crump JG, Huentelman MJ, Friedman RA.

Hum Genet. 2018 Jul;137(6-7):459-470. doi: 10.1007/s00439-018-1898-8. Epub 2018 Jun 28.

23.

Increased Hospital Surgical Volume Reduces Rate of 30- and 90-Day Readmission After Acoustic Neuroma Surgery.

Babadjouni R, Wen T, Donoho DA, Buchanan IA, Cen SY, Friedman RA, Amar A, Russin JJ, Giannotta SL, Mack WJ, Attenello FJ.

Neurosurgery. 2019 Mar 1;84(3):726-732. doi: 10.1093/neuros/nyy187.

PMID:
29889284
24.

Age-related hearing loss: Unraveling the pieces.

Tu NC, Friedman RA.

Laryngoscope Investig Otolaryngol. 2018 Feb 21;3(2):68-72. doi: 10.1002/lio2.134. eCollection 2018 Apr. Review.

25.

HMGB1 links chronic liver injury to progenitor responses and hepatocarcinogenesis.

Hernandez C, Huebener P, Pradere JP, Antoine DJ, Friedman RA, Schwabe RF.

J Clin Invest. 2018 Jun 1;128(6):2436-2451. doi: 10.1172/JCI91786. Epub 2018 May 7. Erratum in: J Clin Invest. 2019 Apr 1;129(4):1803.

26.

Prevalence of Hearing Loss and Hearing Care Use Among Asian Americans: A Nationally Representative Sample.

Choi JS, Kari E, Friedman RA, Fisher LM.

Otol Neurotol. 2018 Feb;39(2):158-167. doi: 10.1097/MAO.0000000000001668.

PMID:
29315179
27.

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.

Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC.

Cancer Cell. 2018 Jan 8;33(1):75-90.e7. doi: 10.1016/j.ccell.2017.11.007. Epub 2017 Dec 14. Erratum in: Cancer Cell. 2018 Nov 12;34(5):863-867.

28.

Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.

Chen X, Deng H, Churchill MJ, Luchsinger LL, Du X, Chu TH, Friedman RA, Middelhoff M, Ding H, Tailor YH, Wang ALE, Liu H, Niu Z, Wang H, Jiang Z, Renders S, Ho SH, Shah SV, Tishchenko P, Chang W, Swayne TC, Munteanu L, Califano A, Takahashi R, Nagar KK, Renz BW, Worthley DL, Westphalen CB, Hayakawa Y, Asfaha S, Borot F, Lin CS, Snoeck HW, Mukherjee S, Wang TC.

Cell Stem Cell. 2017 Dec 7;21(6):747-760.e7. doi: 10.1016/j.stem.2017.11.003. Epub 2017 Nov 30.

29.

MicroRNA-21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis.

Caviglia JM, Yan J, Jang MK, Gwak GY, Affo S, Yu L, Olinga P, Friedman RA, Chen X, Schwabe RF.

Hepatology. 2018 Jun;67(6):2414-2429. doi: 10.1002/hep.29627. Epub 2018 Jan 18.

30.

Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea.

Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA.

PLoS Genet. 2017 Oct 23;13(10):e1007048. doi: 10.1371/journal.pgen.1007048. eCollection 2017 Oct.

31.

Corrigendum: MC4R-dependent suppression of appetite by bone-derived lipocalin 2.

Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nickolas T, Chung W, Zeltser LM, Williams KW, Pessin JE, Kousteni S.

Nature. 2017 Jun 14;546(7658):440. doi: 10.1038/nature22808.

PMID:
28617454
32.

Compound heterozygous mutations in MASP1 in a deaf child with absent cochlear nerves.

Kari E, Schrauwen I, Llaci L, Fisher LM, Go JL, Naymik M, Knowles JA, Huentelman MJ, Friedman RA.

Neurol Genet. 2017 May 11;3(3):e153. doi: 10.1212/NXG.0000000000000153. eCollection 2017 Jun. No abstract available.

33.

Histidine decarboxylase (HDC)-expressing granulocytic myeloid cells induce and recruit Foxp3+ regulatory T cells in murine colon cancer.

Chen X, Takemoto Y, Deng H, Middelhoff M, Friedman RA, Chu TH, Churchill MJ, Ma Y, Nagar KK, Tailor YH, Mukherjee S, Wang TC.

Oncoimmunology. 2017 Feb 10;6(3):e1290034. doi: 10.1080/2162402X.2017.1290034. eCollection 2017.

34.

MC4R-dependent suppression of appetite by bone-derived lipocalin 2.

Mosialou I, Shikhel S, Liu JM, Maurizi A, Luo N, He Z, Huang Y, Zong H, Friedman RA, Barasch J, Lanzano P, Deng L, Leibel RL, Rubin M, Nickolas T, Chung W, Zeltser LM, Williams KW, Pessin JE, Kousteni S.

Nature. 2017 Mar 16;543(7645):385-390. doi: 10.1038/nature21697. Epub 2017 Mar 8. Erratum in: Nature. 2017 Jun 14;546(7658):440.

35.

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.

Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, Torsitano C, McGraw TE, Puchowicz M, Kurland I, Karsenty G.

Cell Metab. 2017 Jan 10;25(1):218. doi: 10.1016/j.cmet.2016.12.003. No abstract available.

36.

A Moral or Medical Problem? The Relationship between Legal Penalties and Treatment Practices for Opioid Use Disorders in Pregnant Women.

Angelotta C, Weiss CJ, Angelotta JW, Friedman RA.

Womens Health Issues. 2016 Nov - Dec;26(6):595-601. doi: 10.1016/j.whi.2016.09.002. Epub 2016 Oct 20.

PMID:
27773527
37.

Negative regulation of NF-κB p65 activity by serine 536 phosphorylation.

Pradère JP, Hernandez C, Koppe C, Friedman RA, Luedde T, Schwabe RF.

Sci Signal. 2016 Aug 23;9(442):ra85. doi: 10.1126/scisignal.aab2820.

38.

Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice.

Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI, Allayee H, Lusis AJ, Ohyama T, Friedman RA.

J Assoc Res Otolaryngol. 2016 Oct;17(5):417-31. doi: 10.1007/s10162-016-0578-4. Epub 2016 Aug 18.

39.

The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction.

Lavinsky J, Ge M, Crow AL, Pan C, Wang J, Salehi P, Myint A, Eskin E, Allayee H, Lusis AJ, Friedman RA.

G3 (Bethesda). 2016 Oct 13;6(10):3219-3228. doi: 10.1534/g3.116.032516.

40.

Gastrin stimulates a cholecystokinin-2-receptor-expressing cardia progenitor cell and promotes progression of Barrett's-like esophagus.

Lee Y, Urbanska AM, Hayakawa Y, Wang H, Au AS, Luna AM, Chang W, Jin G, Bhagat G, Abrams JA, Friedman RA, Varro A, Wang KK, Boyce M, Rustgi AK, Sepulveda AR, Quante M, Wang TC.

Oncotarget. 2017 Jan 3;8(1):203-214. doi: 10.18632/oncotarget.10667.

41.

Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise.

Mera P, Laue K, Ferron M, Confavreux C, Wei J, Galán-Díez M, Lacampagne A, Mitchell SJ, Mattison JA, Chen Y, Bacchetta J, Szulc P, Kitsis RN, de Cabo R, Friedman RA, Torsitano C, McGraw TE, Puchowicz M, Kurland I, Karsenty G.

Cell Metab. 2016 Jun 14;23(6):1078-1092. doi: 10.1016/j.cmet.2016.05.004. Erratum in: Cell Metab. 2017 Jan 10;25(1):218.

42.

Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis.

Westphalen CB, Takemoto Y, Tanaka T, Macchini M, Jiang Z, Renz BW, Chen X, Ormanns S, Nagar K, Tailor Y, May R, Cho Y, Asfaha S, Worthley DL, Hayakawa Y, Urbanska AM, Quante M, Reichert M, Broyde J, Subramaniam PS, Remotti H, Su GH, Rustgi AK, Friedman RA, Honig B, Califano A, Houchen CW, Olive KP, Wang TC.

Cell Stem Cell. 2016 Apr 7;18(4):441-55. doi: 10.1016/j.stem.2016.03.016.

43.

Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer.

Dubeykovskaya Z, Si Y, Chen X, Worthley DL, Renz BW, Urbanska AM, Hayakawa Y, Xu T, Westphalen CB, Dubeykovskiy A, Chen D, Friedman RA, Asfaha S, Nagar K, Tailor Y, Muthupalani S, Fox JG, Kitajewski J, Wang TC.

Nat Commun. 2016 Feb 4;7:10517. doi: 10.1038/ncomms10517.

44.

Large-scale phenotyping of noise-induced hearing loss in 100 strains of mice.

Myint A, White CH, Ohmen JD, Li X, Wang J, Lavinsky J, Salehi P, Crow AL, Ohyama T, Friedman RA.

Hear Res. 2016 Feb;332:113-120. doi: 10.1016/j.heares.2015.12.006. Epub 2015 Dec 17.

45.

Mist1 Expressing Gastric Stem Cells Maintain the Normal and Neoplastic Gastric Epithelium and Are Supported by a Perivascular Stem Cell Niche.

Hayakawa Y, Ariyama H, Stancikova J, Sakitani K, Asfaha S, Renz BW, Dubeykovskaya ZA, Shibata W, Wang H, Westphalen CB, Chen X, Takemoto Y, Kim W, Khurana SS, Tailor Y, Nagar K, Tomita H, Hara A, Sepulveda AR, Setlik W, Gershon MD, Saha S, Ding L, Shen Z, Fox JG, Friedman RA, Konieczny SF, Worthley DL, Korinek V, Wang TC.

Cancer Cell. 2015 Dec 14;28(6):800-814. doi: 10.1016/j.ccell.2015.10.003. Epub 2015 Nov 12.

46.

Phase Ib Randomized, Double-Blinded, Placebo-Controlled, Dose Escalation Study of Polyphenon E in Patients with Barrett's Esophagus.

Joe AK, Schnoll-Sussman F, Bresalier RS, Abrams JA, Hibshoosh H, Cheung K, Friedman RA, Yang CS, Milne GL, Liu DD, Lee JJ, Abdul K, Bigg M, Foreman J, Su T, Wang X, Ahmed A, Neugut AI, Akpa E, Lippman SM, Perloff M, Brown PH, Lightdale CJ.

Cancer Prev Res (Phila). 2015 Dec;8(12):1131-7. doi: 10.1158/1940-6207.CAPR-14-0274-T. Epub 2015 Oct 15.

47.

Solitary Plasmacytoma in the Internal Auditory Canal and Cerebellopontine Angle Mimicking Meningioma.

Lavinsky J, Aaron KA, Christian E, Go JL, Hurth K, Giannotta SL, Friedman RA.

Otol Neurotol. 2016 Dec;37(10):e400-e401. No abstract available.

PMID:
26457817
48.

Prognostic implications of and audiometric evidence for hearing fluctuation in Meniere's disease.

Hoa M, Friedman RA, Fisher LM, Derebery MJ.

Laryngoscope. 2015 Dec;125 Suppl 12:S1-12. doi: 10.1002/lary.25579. Epub 2015 Sep 7.

PMID:
26343803
49.

The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants.

Crow AL, Ohmen J, Wang J, Lavinsky J, Hartiala J, Li Q, Li X, Salehide P, Eskin E, Pan C, Lusis AJ, Allayee H, Friedman RA.

G3 (Bethesda). 2015 Sep 4;5(11):2329-39. doi: 10.1534/g3.115.021592.

50.

A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear.

Schrauwen I, Hasin-Brumshtein Y, Corneveaux JJ, Ohmen J, White C, Allen AN, Lusis AJ, Van Camp G, Huentelman MJ, Friedman RA.

Hear Res. 2016 Mar;333:266-274. doi: 10.1016/j.heares.2015.08.013. Epub 2015 Sep 1.

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