Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 107

1.

Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model.

Goettel JA, Kotlarz D, Emani R, Canavan JB, Konnikova L, Illig D, Frei SM, Field M, Kowalik M, Peng K, Gringauz J, Mitsalis V, Wall SM, Tsou A, Griffith AE, Friedman JR, Towne JE, Plevy SE, O'Hara Hall A, Snapper SB.

Cell Mol Gastroenterol Hepatol. 2019 May 9. pii: S2352-345X(19)30062-1. doi: 10.1016/j.jcmgh.2019.05.001. [Epub ahead of print] No abstract available.

2.

A negative role for the interleukin-2-inducible T-cell kinase (ITK) in human Foxp3+ TREG differentiation.

Mamontov P, Eberwine RA, Perrigoue J, Das A, Friedman JR, Mora JR.

PLoS One. 2019 Apr 25;14(4):e0215963. doi: 10.1371/journal.pone.0215963. eCollection 2019.

3.

A simplified definition of histologic improvement in ulcerative colitis and its association with disease outcomes up to 30 weeks from initiation of therapy: Post-hoc analysis of three clinical trials.

Li K, Strauss R, Marano C, Greenbaum LE, Friedman JR, Peyrin-Biroulet L, Brodmerkel C, De Hertogh G.

J Crohns Colitis. 2019 Feb 4. doi: 10.1093/ecco-jcc/jjz022. [Epub ahead of print]

PMID:
30721964
4.

Gut microbiota density influences host physiology and is shaped by host and microbial factors.

Contijoch EJ, Britton GJ, Yang C, Mogno I, Li Z, Ng R, Llewellyn SR, Hira S, Johnson C, Rabinowitz KM, Barkan R, Dotan I, Hirten RP, Fu SC, Luo Y, Yang N, Luong T, Labrias PR, Lira S, Peter I, Grinspan A, Clemente JC, Kosoy R, Kim-Schulze S, Qin X, Castillo A, Hurley A, Atreja A, Rogers J, Fasihuddin F, Saliaj M, Nolan A, Reyes-Mercedes P, Rodriguez C, Aly S, Santa-Cruz K, Peters L, Suárez-Fariñas M, Huang R, Hao K, Zhu J, Zhang B, Losic B, Irizar H, Song WM, Di Narzo A, Wang W, Cohen BL, DiMaio C, Greenwald D, Itzkowitz S, Lucas A, Marion J, Maser E, Ungaro R, Naymagon S, Novak J, Shah B, Ullman T, Rubin P, George J, Legnani P, Telesco SE, Friedman JR, Brodmerkel C, Plevy S, Cho JH, Colombel JF, Schadt EE, Argmann C, Dubinsky M, Kasarskis A, Sands B, Faith JJ.

Elife. 2019 Jan 22;8. pii: e40553. doi: 10.7554/eLife.40553.

5.

Acetylcholine signaling system in progression of lung cancers.

Friedman JR, Richbart SD, Merritt JC, Brown KC, Nolan NA, Akers AT, Lau JK, Robateau ZR, Miles SL, Dasgupta P.

Pharmacol Ther. 2019 Feb;194:222-254. doi: 10.1016/j.pharmthera.2018.10.002. Epub 2018 Oct 3. Review.

PMID:
30291908
6.

Rapid Diagnosis of KCNQ2-Associated Early Infantile Epileptic Encephalopathy Improved Outcome.

Chen DY, Chowdhury S, Farnaes L, Friedman JR, Honold J, Dimmock DP, Gold OBOTRIJJ.

Pediatr Neurol. 2018 Sep;86:69-70. doi: 10.1016/j.pediatrneurol.2018.06.002. Epub 2018 Jul 10. No abstract available.

PMID:
30107960
7.

Abnormal Small Intestinal Epithelial Microvilli in Patients With Crohn's Disease.

VanDussen KL, Stojmirović A, Li K, Liu TC, Kimes PK, Muegge BD, Simpson KF, Ciorba MA, Perrigoue JG, Friedman JR, Towne JE, Head RD, Stappenbeck TS.

Gastroenterology. 2018 Sep;155(3):815-828. doi: 10.1053/j.gastro.2018.05.028. Epub 2018 May 18.

PMID:
29782846
8.

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.

Guo Y, Walsh AM, Canavan M, Wechalekar MD, Cole S, Yin X, Scott B, Loza M, Orr C, McGarry T, Bombardieri M, Humby F, Proudman SM, Pitzalis C, Smith MD, Friedman JR, Anderson I, Madakamutil L, Veale DJ, Fearon U, Nagpal S.

PLoS One. 2018 Feb 28;13(2):e0192704. doi: 10.1371/journal.pone.0192704. eCollection 2018.

9.

Molecular Comparison of Adult and Pediatric Ulcerative Colitis Indicates Broad Similarity of Molecular Pathways in Disease Tissue.

Li K, Strauss R, Ouahed J, Chan D, Telesco SE, Shouval DS, Canavan JB, Brodmerkel C, Snapper SB, Friedman JR.

J Pediatr Gastroenterol Nutr. 2018 Jul;67(1):45-52. doi: 10.1097/MPG.0000000000001898.

PMID:
29401083
10.

Lipid Homeostasis Is Maintained by Dual Targeting of the Mitochondrial PE Biosynthesis Enzyme to the ER.

Friedman JR, Kannan M, Toulmay A, Jan CH, Weissman JS, Prinz WA, Nunnari J.

Dev Cell. 2018 Jan 22;44(2):261-270.e6. doi: 10.1016/j.devcel.2017.11.023. Epub 2017 Dec 28.

11.

Anticancer Activity of Natural and Synthetic Capsaicin Analogs.

Friedman JR, Nolan NA, Brown KC, Miles SL, Akers AT, Colclough KW, Seidler JM, Rimoldi JM, Valentovic MA, Dasgupta P.

J Pharmacol Exp Ther. 2018 Mar;364(3):462-473. doi: 10.1124/jpet.117.243691. Epub 2017 Dec 15. Review.

12.

Low CSF 5-HIAA in Myoclonus Dystonia.

Peall KJ, Ng J, Dy ME, Sharma N, Pope S, Heales S, Friedman JR, Kurian MA.

Mov Disord. 2017 Nov;32(11):1647-1649. doi: 10.1002/mds.27117. Epub 2017 Sep 26. No abstract available.

13.

A functional genomics predictive network model identifies regulators of inflammatory bowel disease.

Peters LA, Perrigoue J, Mortha A, Iuga A, Song WM, Neiman EM, Llewellyn SR, Di Narzo A, Kidd BA, Telesco SE, Zhao Y, Stojmirovic A, Sendecki J, Shameer K, Miotto R, Losic B, Shah H, Lee E, Wang M, Faith JJ, Kasarskis A, Brodmerkel C, Curran M, Das A, Friedman JR, Fukui Y, Humphrey MB, Iritani BM, Sibinga N, Tarrant TK, Argmann C, Hao K, Roussos P, Zhu J, Zhang B, Dobrin R, Mayer LF, Schadt EE.

Nat Genet. 2017 Oct;49(10):1437-1449. doi: 10.1038/ng.3947. Epub 2017 Sep 11.

14.

GI Research Path: From Academia to the Pharmaceutical Industry.

Friedman JR.

Cell Mol Gastroenterol Hepatol. 2016 Dec 3;3(1):8-10. doi: 10.1016/j.jcmgh.2016.11.003. eCollection 2017 Jan. No abstract available.

15.

System Transformation Under the California Mental Health Services Act: Implementation of Full-Service Partnerships in L.A. County.

Starks SL, Arns PG, Padwa H, Friedman JR, Marrow J, Meldrum ML, Bromley E, Kelly EL, Brekke JS, Braslow JT.

Psychiatr Serv. 2017 Jun 1;68(6):587-595. doi: 10.1176/appi.ps.201500390. Epub 2017 Feb 1.

16.

Capsaicin synergizes with camptothecin to induce increased apoptosis in human small cell lung cancers via the calpain pathway.

Friedman JR, Perry HE, Brown KC, Gao Y, Lin J, Stevenson CD, Hurley JD, Nolan NA, Akers AT, Chen YC, Denning KL, Brown LG, Dasgupta P.

Biochem Pharmacol. 2017 Apr 1;129:54-66. doi: 10.1016/j.bcp.2017.01.004. Epub 2017 Jan 16.

17.

Ustekinumab as Induction and Maintenance Therapy for Crohn's Disease.

Feagan BG, Sandborn WJ, Gasink C, Jacobstein D, Lang Y, Friedman JR, Blank MA, Johanns J, Gao LL, Miao Y, Adedokun OJ, Sands BE, Hanauer SB, Vermeire S, Targan S, Ghosh S, de Villiers WJ, Colombel JF, Tulassay Z, Seidler U, Salzberg BA, Desreumaux P, Lee SD, Loftus EV Jr, Dieleman LA, Katz S, Rutgeerts P; UNITI–IM-UNITI Study Group.

N Engl J Med. 2016 Nov 17;375(20):1946-1960.

18.

ADCY5-related dyskinesia: Comments on characteristic manifestations and variant-associated severity.

Raskind WH, Friedman JR, Roze E, Méneret A, Chen DH, Bird TD.

Mov Disord. 2017 Feb;32(2):305-306. doi: 10.1002/mds.26888. Epub 2016 Dec 9. No abstract available.

19.

Observation of Tunneling-Assisted Highly Forbidden Single-Photon Transitions in a Ni_{4} Single-Molecule Magnet.

Chen Y, Ashkezari MD, Collett CA, Allão Cassaro RA, Troiani F, Lahti PM, Friedman JR.

Phys Rev Lett. 2016 Oct 28;117(18):187202. Epub 2016 Oct 27.

PMID:
27835005
20.

Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit.

Zeharia A, Friedman JR, Tobar A, Saada A, Konen O, Fellig Y, Shaag A, Nunnari J, Elpeleg O.

Eur J Hum Genet. 2016 Dec;24(12):1778-1782. doi: 10.1038/ejhg.2016.83. Epub 2016 Aug 3.

21.

MICOS and phospholipid transfer by Ups2-Mdm35 organize membrane lipid synthesis in mitochondria.

Aaltonen MJ, Friedman JR, Osman C, Salin B, di Rago JP, Nunnari J, Langer T, Tatsuta T.

J Cell Biol. 2016 Jun 6;213(5):525-34. doi: 10.1083/jcb.201602007. Epub 2016 May 30.

22.

Non-pungent long chain capsaicin-analogs arvanil and olvanil display better anti-invasive activity than capsaicin in human small cell lung cancers.

Hurley JD, Akers AT, Friedman JR, Nolan NA, Brown KC, Dasgupta P.

Cell Adh Migr. 2017 Jan 2;11(1):80-97. doi: 10.1080/19336918.2016.1187368. Epub 2016 May 19.

23.

What Is Not in the Name? Dopa-Responsive Dystonia May Respond to More Than L-Dopa.

Friedman JR.

Pediatr Neurol. 2016 Jun;59:76-80. doi: 10.1016/j.pediatrneurol.2015.12.016. Epub 2016 Mar 4.

PMID:
27080360
24.

MicroRNA-122 regulates polyploidization in the murine liver.

Hsu SH, Delgado ER, Otero PA, Teng KY, Kutay H, Meehan KM, Moroney JB, Monga JK, Hand NJ, Friedman JR, Ghoshal K, Duncan AW.

Hepatology. 2016 Aug;64(2):599-615. doi: 10.1002/hep.28573. Epub 2016 May 12.

25.

Toward clinical genomics in everyday medicine: perspectives and recommendations.

Delaney SK, Hultner ML, Jacob HJ, Ledbetter DH, McCarthy JJ, Ball M, Beckman KB, Belmont JW, Bloss CS, Christman MF, Cosgrove A, Damiani SA, Danis T, Delledonne M, Dougherty MJ, Dudley JT, Faucett WA, Friedman JR, Haase DH, Hays TS, Heilsberg S, Huber J, Kaminsky L, Ledbetter N, Lee WH, Levin E, Libiger O, Linderman M, Love RL, Magnus DC, Martland A, McClure SL, Megill SE, Messier H, Nussbaum RL, Palaniappan L, Patay BA, Popovich BW, Quackenbush J, Savant MJ, Su MM, Terry SF, Tucker S, Wong WT, Green RC.

Expert Rev Mol Diagn. 2016;16(5):521-32. doi: 10.1586/14737159.2016.1146593. Epub 2016 Feb 24.

26.

ADCY5 mutation carriers display pleiotropic paroxysmal day and nighttime dyskinesias.

Friedman JR, Méneret A, Chen DH, Trouillard O, Vidailhet M, Raskind WH, Roze E.

Mov Disord. 2016 Jan;31(1):147-8. doi: 10.1002/mds.26494. Epub 2015 Dec 21. No abstract available.

27.

ADCY5-related dyskinesia: Broader spectrum and genotype-phenotype correlations.

Chen DH, Méneret A, Friedman JR, Korvatska O, Gad A, Bonkowski ES, Stessman HA, Doummar D, Mignot C, Anheim M, Bernes S, Davis MY, Damon-Perrière N, Degos B, Grabli D, Gras D, Hisama FM, Mackenzie KM, Swanson PD, Tranchant C, Vidailhet M, Winesett S, Trouillard O, Amendola LM, Dorschner MO, Weiss M, Eichler EE, Torkamani A, Roze E, Bird TD, Raskind WH.

Neurology. 2015 Dec 8;85(23):2026-35. doi: 10.1212/WNL.0000000000002058. Epub 2015 Nov 4.

28.

The Koolen-de Vries syndrome: a phenotypic comparison of patients with a 17q21.31 microdeletion versus a KANSL1 sequence variant.

Koolen DA, Pfundt R, Linda K, Beunders G, Veenstra-Knol HE, Conta JH, Fortuna AM, Gillessen-Kaesbach G, Dugan S, Halbach S, Abdul-Rahman OA, Winesett HM, Chung WK, Dalton M, Dimova PS, Mattina T, Prescott K, Zhang HZ, Saal HM, Hehir-Kwa JY, Willemsen MH, Ockeloen CW, Jongmans MC, Van der Aa N, Failla P, Barone C, Avola E, Brooks AS, Kant SG, Gerkes EH, Firth HV, Õunap K, Bird LM, Masser-Frye D, Friedman JR, Sokunbi MA, Dixit A, Splitt M; DDD Study, Kukolich MK, McGaughran J, Coe BP, Flórez J, Nadif Kasri N, Brunner HG, Thompson EM, Gecz J, Romano C, Eichler EE, de Vries BB.

Eur J Hum Genet. 2016 May;24(5):652-9. doi: 10.1038/ejhg.2015.178. Epub 2015 Aug 26.

29.

"A world crazier than us": Vanishing social contexts and the consequences for psychiatric practice in contemporary Romania.

Friedman JR.

Transcult Psychiatry. 2016 Apr;53(2):176-97. doi: 10.1177/1363461515590917. Epub 2015 Jul 1.

PMID:
26134545
30.

MICOS coordinates with respiratory complexes and lipids to establish mitochondrial inner membrane architecture.

Friedman JR, Mourier A, Yamada J, McCaffery JM, Nunnari J.

Elife. 2015 Apr 28;4. doi: 10.7554/eLife.07739.

31.

A genome sequencing program for novel undiagnosed diseases.

Bloss CS, Zeeland AA, Topol SE, Darst BF, Boeldt DL, Erikson GA, Bethel KJ, Bjork RL, Friedman JR, Hwynn N, Patay BA, Pockros PJ, Scott ER, Simon RA, Williams GW, Schork NJ, Topol EJ, Torkamani A.

Genet Med. 2015 Dec;17(12):995-1001. doi: 10.1038/gim.2015.21. Epub 2015 Mar 19. Erratum in: Genet Med. 2015 Jun;17(6):515.

32.

Instrument for in-situ orientation of superconducting thin-film resonators used for electron-spin resonance experiments.

Mowry A, Chen Y, Kubasek J, Friedman JR.

Rev Sci Instrum. 2015 Jan;86(1):014702. doi: 10.1063/1.4905176.

PMID:
25638103
33.

De novo KCNB1 mutations in epileptic encephalopathy.

Torkamani A, Bersell K, Jorge BS, Bjork RL Jr, Friedman JR, Bloss CS, Cohen J, Gupta S, Naidu S, Vanoye CG, George AL Jr, Kearney JA.

Ann Neurol. 2014 Oct;76(4):529-540. doi: 10.1002/ana.24263. Epub 2014 Sep 19.

34.

Pediatric eosinophilic esophagitis is associated with changes in esophageal microRNAs.

Zahm AM, Menard-Katcher C, Benitez AJ, Tsoucas DM, Le Guen CL, Hand NJ, Friedman JR.

Am J Physiol Gastrointest Liver Physiol. 2014 Oct 15;307(8):G803-12. doi: 10.1152/ajpgi.00121.2014. Epub 2014 Aug 21.

35.

Collective coupling of a macroscopic number of single-molecule magnets with a microwave cavity mode.

Eddins AW, Beedle CC, Hendrickson DN, Friedman JR.

Phys Rev Lett. 2014 Mar 28;112(12):120501. Epub 2014 Mar 26.

PMID:
24724636
36.

Gain-of-function ADCY5 mutations in familial dyskinesia with facial myokymia.

Chen YZ, Friedman JR, Chen DH, Chan GC, Bloss CS, Hisama FM, Topol SE, Carson AR, Pham PH, Bonkowski ES, Scott ER, Lee JK, Zhang G, Oliveira G, Xu J, Scott-Van Zeeland AA, Chen Q, Levy S, Topol EJ, Storm D, Swanson PD, Bird TD, Schork NJ, Raskind WH, Torkamani A.

Ann Neurol. 2014 Apr;75(4):542-9. doi: 10.1002/ana.24119. Epub 2014 Mar 13.

37.

Rectal microRNAs are perturbed in pediatric inflammatory bowel disease of the colon.

Zahm AM, Hand NJ, Tsoucas DM, Le Guen CL, Baldassano RN, Friedman JR.

J Crohns Colitis. 2014 Sep;8(9):1108-17. doi: 10.1016/j.crohns.2014.02.012. Epub 2014 Mar 7.

38.

Novel targets of miR-30, a microRNA required for biliary development.

Le Guen CL, Friedman JR, Hand NJ.

F1000Res. 2013 Sep 24;2:197. doi: 10.12688/f1000research.2-197.v1. eCollection 2013.

39.

Mitochondrial form and function.

Friedman JR, Nunnari J.

Nature. 2014 Jan 16;505(7483):335-43. doi: 10.1038/nature12985. Review.

40.

Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets.

Kameswaran V, Bramswig NC, McKenna LB, Penn M, Schug J, Hand NJ, Chen Y, Choi I, Vourekas A, Won KJ, Liu C, Vivek K, Naji A, Friedman JR, Kaestner KH.

Cell Metab. 2014 Jan 7;19(1):135-45. doi: 10.1016/j.cmet.2013.11.016. Epub 2013 Dec 26.

41.

Red muscle proportions and enzyme activities in deep-sea demersal fishes.

Drazen JC, Dugan B, Friedman JR.

J Fish Biol. 2013 Dec;83(6):1592-612. doi: 10.1111/jfb.12268. Review.

PMID:
24298953
42.

ER exit sites are physical and functional core autophagosome biogenesis components.

Graef M, Friedman JR, Graham C, Babu M, Nunnari J.

Mol Biol Cell. 2013 Sep;24(18):2918-31. doi: 10.1091/mbc.E13-07-0381. Epub 2013 Jul 31.

43.

An unusual presentation of posterior fossa ependymoma in a child.

Crawford JR, Newbury RO, Friedman JR.

BMJ Case Rep. 2013 Jul 5;2013. pii: bcr2013010267. doi: 10.1136/bcr-2013-010267. No abstract available.

44.

Extrahepatic cholangiocyte cilia are abnormal in biliary atresia.

Karjoo S, Hand NJ, Loarca L, Russo PA, Friedman JR, Wells RG.

J Pediatr Gastroenterol Nutr. 2013 Jul;57(1):96-101. doi: 10.1097/MPG.0b013e318296e525.

45.

Dynamic recruitment of microRNAs to their mRNA targets in the regenerating liver.

Schug J, McKenna LB, Walton G, Hand N, Mukherjee S, Essuman K, Shi Z, Gao Y, Markley K, Nakagawa M, Kameswaran V, Vourekas A, Friedman JR, Kaestner KH, Greenbaum LE.

BMC Genomics. 2013 Apr 18;14:264. doi: 10.1186/1471-2164-14-264.

46.

Geometric-phase interference in a Mn12 single-molecule magnet with fourfold rotational symmetry.

Adams ST, da Silva Neto EH, Datta S, Ware JF, Lampropoulos C, Christou G, Myaesoedov Y, Zeldov E, Friedman JR.

Phys Rev Lett. 2013 Feb 22;110(8):087205. Epub 2013 Feb 20.

PMID:
23473196
47.

Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature.

Friedman JR, Dibenedetto JR, West M, Rowland AA, Voeltz GK.

Mol Biol Cell. 2013 Apr;24(7):1030-40. doi: 10.1091/mbc.E12-10-0733. Epub 2013 Feb 6.

48.

miR-122 regulates hepatic lipid metabolism and tumor suppression.

Wen J, Friedman JR.

J Clin Invest. 2012 Aug;122(8):2773-6. doi: 10.1172/JCI63966. Epub 2012 Jul 23.

49.

Circulating microRNA is a biomarker of biliary atresia.

Zahm AM, Hand NJ, Boateng LA, Friedman JR.

J Pediatr Gastroenterol Nutr. 2012 Oct;55(4):366-9.

50.

Identification of the DotL coupling protein subcomplex of the Legionella Dot/Icm type IV secretion system.

Vincent CD, Friedman JR, Jeong KC, Sutherland MC, Vogel JP.

Mol Microbiol. 2012 Jul;85(2):378-91. doi: 10.1111/j.1365-2958.2012.08118.x. Epub 2012 Jun 14.

Supplemental Content

Loading ...
Support Center