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APOL1 and Kidney Disease: From Genetics to Biology.

Friedman DJ, Pollak MR.

Annu Rev Physiol. 2019 Nov 11. doi: 10.1146/annurev-physiol-021119-034345. [Epub ahead of print]


Long-Term Prognostic Value of Less Stringent Electrocardiographic Q Waves and Fourth Universal Definition of Myocardial Infarction Q Waves.

Polcwiartek C, Kragholm K, Friedman DJ, Atwater BD, Graff C, Nielsen JB, Holst AG, Struijk JJ, Pietersen AH, Svendsen JH, Køber L, Søgaard P, Jensen SE, Torp-Pedersen C, Hansen SM.

Am J Med. 2019 Oct 21. pii: S0002-9343(19)30859-9. doi: 10.1016/j.amjmed.2019.08.056. [Epub ahead of print]


Apolipoprotein L1 (APOL1) risk variant toxicity depends on the haplotype background.

Lannon H, Shah SS, Dias L, Blackler D, Alper SL, Pollak MR, Friedman DJ.

Kidney Int. 2019 Aug 1. pii: S0085-2538(19)30777-X. doi: 10.1016/j.kint.2019.07.010. [Epub ahead of print]


APOL1 gene variants and kidney disease in whites: the cardiovascular health study.

Drury ER, Friedman DJ, Pollak MR, Ix JH, Kuller LH, Tracy RP, Mukamal KJ.

Nephrol Dial Transplant. 2019 Oct 3. pii: gfz186. doi: 10.1093/ndt/gfz186. [Epub ahead of print] No abstract available.


Complications involving the subcutaneous implantable cardioverter-defibrillator: Lessons learned from MAUDE.

Zeitler EP, Friedman DJ, Loring Z, Campbell KB, Goldstein SA, Wegermann ZK, Schutz J, Smith N, Black-Maier E, Al-Khatib SM, Piccini JP.

Heart Rhythm. 2019 Sep 24. pii: S1547-5271(19)30857-4. doi: 10.1016/j.hrthm.2019.09.024. [Epub ahead of print]


APOL1 Kidney Risk Variants Induce Cell Death via Mitochondrial Translocation and Opening of the Mitochondrial Permeability Transition Pore.

Shah SS, Lannon H, Dias L, Zhang JY, Alper SL, Pollak MR, Friedman DJ.

J Am Soc Nephrol. 2019 Sep 26. pii: ASN.2019020114. doi: 10.1681/ASN.2019020114. [Epub ahead of print]


Non-invasively quantified changes in left ventricular activation predict outcomes in patients undergoing cardiac resynchronization therapy.

Friedman DJ, Emerek K, Hansen SM, Polcwiartek C, Sørensen PL, Loring Z, Sutter J, Søgaard P, Kisslo J, Graff C, Atwater BD.

J Cardiovasc Electrophysiol. 2019 Nov;30(11):2475-2483. doi: 10.1111/jce.14192. Epub 2019 Oct 8.


PR Prolongation predicts inadequate resynchronization with biventricular pacing in left bundle branch block.

Atwater BD, Emerek K, Sørensen PL, Hansen SM, Loring Z, Graff C, Polcwiartek C, Kisslo J, Søgaard P, Friedman DJ.

Pacing Clin Electrophysiol. 2019 Nov;42(11):1477-1485. doi: 10.1111/pace.13802. Epub 2019 Sep 22.


High performance III-V photoelectrodes for solar water splitting via synergistically tailored structure and stoichiometry.

Lim H, Young JL, Geisz JF, Friedman DJ, Deutsch TG, Yoon J.

Nat Commun. 2019 Jul 29;10(1):3388. doi: 10.1038/s41467-019-11351-1.


APOL1-Associated Kidney Disease in Brazil.

Riella C, Siemens TA, Wang M, Campos RP, Moraes TP, Riella LV, Friedman DJ, Riella MC, Pollak MR.

Kidney Int Rep. 2019 Mar 20;4(7):923-929. doi: 10.1016/j.ekir.2019.03.006. eCollection 2019 Jul.


Investigating Possible Infectious Causes of Chronic Kidney Disease of Unknown Etiology in a Nicaraguan Mining Community.

Yih WK, Kulldorff M, Friedman DJ, Leibler JH, Amador JJ, López-Pilarte D, Galloway RL, Ramírez-Rubio O, Riefkohl A, Brooks DR.

Am J Trop Med Hyg. 2019 Sep;101(3):676-683. doi: 10.4269/ajtmh.18-0856.


Contributions of Rare Gene Variants to Familial and Sporadic FSGS.

Wang M, Chun J, Genovese G, Knob AU, Benjamin A, Wilkins MS, Friedman DJ, Appel GB, Lifton RP, Mane S, Pollak MR.

J Am Soc Nephrol. 2019 Sep;30(9):1625-1640. doi: 10.1681/ASN.2019020152. Epub 2019 Jul 15.


Electrocardiogram Characteristics and Their Association With Psychotropic Drugs Among Patients With Schizophrenia.

Polcwiartek C, Kragholm K, Hansen SM, Atwater BD, Friedman DJ, Barcella CA, Graff C, Nielsen JB, Pietersen A, Nielsen J, Søgaard P, Torp-Pedersen C, Jensen SE.

Schizophr Bull. 2019 Jun 20. pii: sbz064. doi: 10.1093/schbul/sbz064. [Epub ahead of print]


Watchman implantation in a patient with left atrial appendage thrombus.

Friedman DJ, Greene SJ, Piccini JP, Vemulapalli S, Jackson KP.

J Cardiovasc Electrophysiol. 2019 Sep;30(9):1694-1695. doi: 10.1111/jce.14031. Epub 2019 Jul 2. No abstract available.


The Association of a classical left bundle Branch Block Contraction Pattern by vendor-independent strain echocardiography and outcome after cardiac resynchronization therapy.

Emerek K, Friedman DJ, Sørensen PL, Hansen SM, Larsen JM, Risum N, Thøgersen AM, Graff C, Atwater BD, Kisslo J, Søgaard P.

Cardiovasc Ultrasound. 2019 May 21;17(1):10. doi: 10.1186/s12947-019-0160-4.


Catheter Ablation of Atrial Fibrillation With and Without On-Site Cardiothoracic Surgery.

Friedman DJ, Pokorney SD, Khanna R, Goldstein L, Atwater BD, Bahnson TD, Daubert JP, Jackson KP, Heist EK, Singh JP, Calkins H, Piccini JP.

J Am Coll Cardiol. 2019 May 21;73(19):2487-2489. doi: 10.1016/j.jacc.2019.02.036. No abstract available.


Premature ventricular contraction response-induced new-onset atrial fibrillation.

Friedman DJ, Chasten T, Anderson K, Mullenix J, Rider K, Sun AY.

HeartRhythm Case Rep. 2018 Nov 30;5(3):120-123. doi: 10.1016/j.hrcr.2018.11.012. eCollection 2019 Mar. No abstract available.


Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity.

Chun J, Zhang JY, Wilkins MS, Subramanian B, Riella C, Magraner JM, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3712-3721. doi: 10.1073/pnas.1820414116. Epub 2019 Feb 7.


How to Implant Cardiac Resynchronization Therapy in a Busy Clinical Practice.

Friedman DJ, Jackson KP.

Card Electrophysiol Clin. 2019 Mar;11(1):67-74. doi: 10.1016/j.ccep.2018.11.009. Review.


Use of left atrial appendage occlusion among older cardiac surgery patients with preoperative atrial fibrillation: a national cohort study.

Friedman DJ, Gaca JG, Wang T, Malaisrie SC, Holmes DR, Piccini JP, Suri RM, Mack MJ, Badhwar V, Jacobs JP, Peterson ED, Chow SC, Matthew Brennan J.

J Interv Card Electrophysiol. 2019 Feb 2. doi: 10.1007/s10840-019-00519-w. [Epub ahead of print]


Is Time From Last Hospitalization for Heart Failure to Placement of a Primary Prevention Implantable Cardioverter-Defibrillator Associated With Patient Outcomes?

Ambrosy AP, Parzynski CS, Friedman DJ, Fudim M, Hernandez AF, Fonarow GC, Masoudi FA, Al-Khatib SM.

Circulation. 2018 Dec 11;138(24):2787-2797. doi: 10.1161/CIRCULATIONAHA.118.035627.


Size Matters: Normalization of QRS Duration to Left Ventricular Dimension Improves Prediction of Long-Term Cardiac Resynchronization Therapy Outcome.

Zweerink A, Friedman DJ, Klem I, van de Ven PM, Vink C, Biesbroek PS, Hansen SM, Emerek K, Kim RJ, van Rossum AC, Atwater BD, Nijveldt R, Allaart CP.

Circ Arrhythm Electrophysiol. 2018 Dec;11(12):e006767. doi: 10.1161/CIRCEP.118.006767.


Preventing overdiagnosis and the harms of too much sport and exercise medicine.

Friedman DJ, Khan KM.

Br J Sports Med. 2019 Oct;53(20):1314-1318. doi: 10.1136/bjsports-2018-100039. Epub 2018 Dec 5. No abstract available.


Genes and environment in chronic kidney disease hotspots.

Friedman DJ.

Curr Opin Nephrol Hypertens. 2019 Jan;28(1):87-96. doi: 10.1097/MNH.0000000000000470. Review.


The mechanical and hemodynamic effects of left ventricular pacing in heart failure with preserved ejection fraction and left bundle branch block.

Friedman DJ, Emerek K, Søgaard P, Vejdani-Jahromi M, Kisslo J, Atwater BD.

J Electrocardiol. 2018 Sep - Oct;51(5):859-862. doi: 10.1016/j.jelectrocard.2018.07.004. Epub 2018 Jul 10.


Pitfalls in programming: The HV and VH intervals in his bundle pacing.

Loring Z, Friedman DJ, Sun AY, Atwater BD.

J Electrocardiol. 2018 Sep - Oct;51(5):776-778. doi: 10.1016/j.jelectrocard.2018.06.002. Epub 2018 Jun 5. No abstract available.


Vectorcardiographic QRS area is associated with long-term outcome after cardiac resynchronization therapy.

Emerek K, Friedman DJ, Sørensen PL, Hansen SM, Larsen JM, Risum N, Thøgersen AM, Graff C, Kisslo J, Søgaard P, Atwater BD.

Heart Rhythm. 2019 Feb;16(2):213-219. doi: 10.1016/j.hrthm.2018.08.028. Epub 2018 Aug 28.


Acute Kidney Injury in Sugarcane Workers at Risk for Mesoamerican Nephropathy.

Kupferman J, Ramírez-Rubio O, Amador JJ, López-Pilarte D, Wilker EH, Laws RL, Sennett C, Robles NV, Lau JL, Salinas AJ, Kaufman JS, Weiner DE, Scammell MK, McClean MD, Brooks DR, Friedman DJ.

Am J Kidney Dis. 2018 Oct;72(4):475-482. doi: 10.1053/j.ajkd.2018.04.014. Epub 2018 Jul 2.


The relationship between baseline and follow-up left ventricular ejection fraction with adverse events among primary prevention ICD patients.

Friedman DJ, Fudim M, Overton R, Shaw LK, Patel D, Pokorney SD, Velazquez EJ, Al-Khatib SM.

Am Heart J. 2018 Jul;201:17-24. doi: 10.1016/j.ahj.2018.03.017. Epub 2018 Apr 4.


Exome Sequencing for CKD Diagnosis: Coming Soon to a Clinic Near You?

Friedman DJ.

Am J Kidney Dis. 2018 Nov;72(5):761-763. doi: 10.1053/j.ajkd.2018.03.014. Epub 2018 Jun 14. No abstract available.


Uninterrupted apixaban for atrial fibrillation ablation is a reasonable alternative, but what is the significance of silent cerebral infarctions?

Friedman DJ, Granger CB.

Eur Heart J. 2018 Aug 21;39(32):2956-2958. doi: 10.1093/eurheartj/ehy274. No abstract available.


Implantable cardioverter-defibrillators in heart failure patients with reduced ejection fraction and diabetes.

Sharma A, Al-Khatib SM, Ezekowitz JA, Cooper LB, Fordyce CB, Michael Felker G, Bardy GH, Poole JE, Thomas Bigger J, Buxton AE, Moss AJ, Friedman DJ, Lee KL, Steinman R, Dorian P, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Peterson ED, Inoue LYT, Sanders GD.

Eur J Heart Fail. 2018 Jun;20(6):1031-1038. doi: 10.1002/ejhf.1192. Epub 2018 May 15.


The impact of solid organ transplant history on inpatient complications, mortality, length of stay, and cost for primary total shoulder arthroplasty admissions in the United States.

Malcolm TL, Chatha K, Breceda AP, Guo E, Friedman DJ, Sabesan VJ, Barsoum WK.

J Shoulder Elbow Surg. 2018 Aug;27(8):1429-1436. doi: 10.1016/j.jse.2018.02.064. Epub 2018 May 4.


Peeling back of left bundle branch refractoriness facilitates mapping of a hemodynamically unstable atrial flutter.

Friedman DJ, Atwater BD.

J Cardiovasc Electrophysiol. 2018 Sep;29(9):1319-1320. doi: 10.1111/jce.13617. Epub 2018 May 15. No abstract available.


A Review of Global Literature on Using Administrative Data to Estimate Prevalence of Intellectual and Developmental Disabilities.

Friedman DJ, Parrish RG, Fox MH.

J Policy Pract Intellect Disabil. 2018 Mar;15(1):43-62. doi: 10.1111/jppi.12220. Epub 2018 Jan 26.


Left Atrial Appendage Electrical Isolation for Treatment of Recurrent Atrial Fibrillation: A Meta-Analysis.

Friedman DJ, Black-Maier EW, Barnett AS, Pokorney SD, Al-Khatib SM, Jackson KP, Bahnson TD, Ellis CR, Atwater BD, Lewis RK, Piccini JP.

JACC Clin Electrophysiol. 2018 Jan;4(1):112-120. doi: 10.1016/j.jacep.2017.07.007. Epub 2017 Sep 13.


UBD modifies APOL1-induced kidney disease risk.

Zhang JY, Wang M, Tian L, Genovese G, Yan P, Wilson JG, Thadhani R, Mottl AK, Appel GB, Bick AG, Sampson MG, Alper SL, Friedman DJ, Pollak MR.

Proc Natl Acad Sci U S A. 2018 Mar 27;115(13):3446-3451. doi: 10.1073/pnas.1716113115. Epub 2018 Mar 12.


Burden of preoperative atrial fibrillation in patients undergoing coronary artery bypass grafting.

Malaisrie SC, McCarthy PM, Kruse J, Matsouaka R, Andrei AC, Grau-Sepulveda MV, Friedman DJ, Cox JL, Brennan JM.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2358-2367.e1. doi: 10.1016/j.jtcvs.2018.01.069. Epub 2018 Feb 9.


Modulation of tubular solute reuptake in UMOD knockout mice.

Friedman DJ, Alper SL.

Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F238-F240. doi: 10.1152/ajprenal.00080.2018. Epub 2018 Mar 7. No abstract available.


Ventricular Fibrillation Conversion Testing After Implantation of a Subcutaneous Implantable Cardioverter Defibrillator: Report From the National Cardiovascular Data Registry.

Friedman DJ, Parzynski CS, Heist EK, Russo AM, Akar JG, Freeman JV, Curtis JP, Al-Khatib SM.

Circulation. 2018 Jun 5;137(23):2463-2477. doi: 10.1161/CIRCULATIONAHA.117.032167. Epub 2018 Feb 20.


When Is It Safe Not to Reimplant an Implantable Cardioverter Defibrillator at the Time of Battery Depletion?

Al-Khatib SM, Friedman DJ, Sanders GD.

Card Electrophysiol Clin. 2018 Mar;10(1):137-144. doi: 10.1016/j.ccep.2017.11.014. Review.


Association Between Left Atrial Appendage Occlusion and Readmission for Thromboembolism Among Patients With Atrial Fibrillation Undergoing Concomitant Cardiac Surgery.

Friedman DJ, Piccini JP, Wang T, Zheng J, Malaisrie SC, Holmes DR, Suri RM, Mack MJ, Badhwar V, Jacobs JP, Gaca JG, Chow SC, Peterson ED, Brennan JM.

JAMA. 2018 Jan 23;319(4):365-374. doi: 10.1001/jama.2017.20125.


Predicting AF recurrence after catheter ablation: Is it time to use the force?

Friedman DJ, Piccini JP.

J Cardiovasc Electrophysiol. 2018 Feb;29(2):272-273. doi: 10.1111/jce.13408. Epub 2018 Jan 22. No abstract available.


Are We Approaching Chronotropy (In)competently?

Atwater BD, Friedman DJ.

JACC Heart Fail. 2018 Feb;6(2):114-116. doi: 10.1016/j.jchf.2017.10.002. Epub 2017 Dec 6. No abstract available.


A Brief History of APOL1: A Gene Evolving.

Friedman DJ.

Semin Nephrol. 2017 Nov;37(6):508-513. doi: 10.1016/j.semnephrol.2017.07.003. Review.


Reply: The Benefit of Cardiac Resynchronization Therapy Is Not Hindered by the Number of Comorbidities.

Zeitler EP, Friedman DJ, Daubert JP, Al-Khatib SM, Solomon SD, Biton Y, McNitt S, Zareba W, Moss AJ, Kutyifa V.

J Am Coll Cardiol. 2017 Oct 17;70(16):2097-2098. doi: 10.1016/j.jacc.2017.07.795. No abstract available.


Obstructive sleep apnea is associated with increased rotor burden in patients undergoing focal impulse and rotor modification guided atrial fibrillation ablation.

Friedman DJ, Liu P, Barnett AS, Campbell KB, Jackson KP, Bahnson TD, Daubert JP, Piccini JP.

Europace. 2018 Nov 1;20(FI_3):f337-f342. doi: 10.1093/europace/eux248.


New York Heart Association class and the survival benefit from primary prevention implantable cardioverter defibrillators: A pooled analysis of 4 randomized controlled trials.

Friedman DJ, Al-Khatib SM, Zeitler EP, Han J, Bardy GH, Poole JE, Bigger JT, Buxton AE, Moss AJ, Lee KL, Steinman R, Dorian P, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Inoue LYT, Sanders GD.

Am Heart J. 2017 Sep;191:21-29. doi: 10.1016/j.ahj.2017.06.002. Epub 2017 Jun 9. Review.


Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40.

Messenheimer DJ, Jensen SM, Afentoulis ME, Wegmann KW, Feng Z, Friedman DJ, Gough MJ, Urba WJ, Fox BA.

Clin Cancer Res. 2017 Oct 15;23(20):6165-6177. doi: 10.1158/1078-0432.CCR-16-2677. Epub 2017 Aug 28.

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