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Items: 1 to 50 of 220

1.

Lévy-like movement patterns of metastatic cancer cells revealed in microfabricated systems and implicated in vivo.

Huda S, Weigelin B, Wolf K, Tretiakov KV, Polev K, Wilk G, Iwasa M, Emami FS, Narojczyk JW, Banaszak M, Soh S, Pilans D, Vahid A, Makurath M, Friedl P, Borisy GG, Kandere-Grzybowska K, Grzybowski BA.

Nat Commun. 2018 Oct 31;9(1):4539. doi: 10.1038/s41467-018-06563-w.

2.

Intravital microscopy of osteolytic progression and therapy response of cancer lesions in the bone.

Dondossola E, Alexander S, Holzapfel BM, Filippini S, Starbuck MW, Hoffman RM, Navone N, De-Juan-Pardo EM, Logothetis CJ, Hutmacher DW, Friedl P.

Sci Transl Med. 2018 Aug 1;10(452). pii: eaao5726. doi: 10.1126/scitranslmed.aao5726.

PMID:
30068572
3.

Cancer invasion into musculature: Mechanics, molecules and implications.

Beunk L, Brown K, Nagtegaal I, Friedl P, Wolf K.

Semin Cell Dev Biol. 2018 Sep 4. pii: S1084-9521(17)30555-4. doi: 10.1016/j.semcdb.2018.07.014. [Epub ahead of print] Review.

PMID:
30009945
4.

Intravital microscopy of collective invasion plasticity in breast cancer.

Ilina O, Campanello L, Gritsenko PG, Vullings M, Wang C, Bult P, Losert W, Friedl P.

Dis Model Mech. 2018 Aug 23;11(9). pii: dmm034330. doi: 10.1242/dmm.034330.

5.

Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma.

Odenthal J, Rijpkema M, Bos D, Wagena E, Croes H, Grenman R, Boerman O, Takes R, Friedl P.

Sci Rep. 2018 Jul 11;8(1):10467. doi: 10.1038/s41598-018-28059-9.

6.

Adaptive adhesion systems mediate glioma cell invasion in complex environments.

Gritsenko PG, Friedl P.

J Cell Sci. 2018 Aug 13;131(15). pii: jcs216382. doi: 10.1242/jcs.216382.

PMID:
29991514
7.

Rational Design of Mouse Models for Cancer Research.

Landgraf M, McGovern JA, Friedl P, Hutmacher DW.

Trends Biotechnol. 2018 Mar;36(3):242-251. doi: 10.1016/j.tibtech.2017.12.001. Epub 2018 Jan 5. Review.

PMID:
29310843
8.

Mechanoreciprocity in cell migration.

van Helvert S, Storm C, Friedl P.

Nat Cell Biol. 2018 Jan;20(1):8-20. doi: 10.1038/s41556-017-0012-0. Epub 2017 Dec 21. Review.

PMID:
29269951
9.

Collective invasion in ductal and lobular breast cancer associates with distant metastasis.

Khalil AA, Ilina O, Gritsenko PG, Bult P, Span PN, Friedl P.

Clin Exp Metastasis. 2017 Oct;34(6-7):421-429. doi: 10.1007/s10585-017-9858-6. Epub 2017 Sep 11.

10.

Recapitulating in vivo-like plasticity of glioma cell invasion along blood vessels and in astrocyte-rich stroma.

Gritsenko P, Leenders W, Friedl P.

Histochem Cell Biol. 2017 Oct;148(4):395-406. doi: 10.1007/s00418-017-1604-2. Epub 2017 Aug 19.

11.

Single cell-based automated quantification of therapy responses of invasive cancer spheroids in organotypic 3D culture.

Veelken C, Bakker GJ, Drell D, Friedl P.

Methods. 2017 Sep 1;128:139-149. doi: 10.1016/j.ymeth.2017.07.015. Epub 2017 Jul 22.

PMID:
28739118
12.

Extracellular protonation modulates cell-cell interaction mechanics and tissue invasion in human melanoma cells.

Hofschröer V, Koch KA, Ludwig FT, Friedl P, Oberleithner H, Stock C, Schwab A.

Sci Rep. 2017 Feb 13;7:42369. doi: 10.1038/srep42369.

13.

Tuning Collective Cell Migration by Cell-Cell Junction Regulation.

Friedl P, Mayor R.

Cold Spring Harb Perspect Biol. 2017 Apr 3;9(4). pii: a029199. doi: 10.1101/cshperspect.a029199. Review.

PMID:
28096261
14.

Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells.

Lehmann S, Te Boekhorst V, Odenthal J, Bianchi R, van Helvert S, Ikenberg K, Ilina O, Stoma S, Xandry J, Jiang L, Grenman R, Rudin M, Friedl P.

Curr Biol. 2017 Feb 6;27(3):392-400. doi: 10.1016/j.cub.2016.11.057. Epub 2017 Jan 12.

15.

Plasticity of tumor cell invasion: governance by growth factors and cytokines.

Odenthal J, Takes R, Friedl P.

Carcinogenesis. 2016 Dec;37(12):1117-1128. Epub 2016 Sep 23. Review.

PMID:
27664164
16.

Plasticity of Cancer Cell Invasion-Mechanisms and Implications for Therapy.

Te Boekhorst V, Friedl P.

Adv Cancer Res. 2016;132:209-64. doi: 10.1016/bs.acr.2016.07.005. Epub 2016 Aug 17. Review.

PMID:
27613134
17.

Plasticity of Cell Migration In Vivo and In Silico.

Te Boekhorst V, Preziosi L, Friedl P.

Annu Rev Cell Dev Biol. 2016 Oct 6;32:491-526. Epub 2016 Aug 26. Review.

PMID:
27576118
18.

Cancer cells: Stemness shaped by curvature.

Weigelin B, Friedl P.

Nat Mater. 2016 Jul 22;15(8):827-8. doi: 10.1038/nmat4711. No abstract available.

PMID:
27443907
19.

Strain Stiffening of Fibrillar Collagen during Individual and Collective Cell Migration Identified by AFM Nanoindentation.

van Helvert S, Friedl P.

ACS Appl Mater Interfaces. 2016 Aug 31;8(34):21946-55. doi: 10.1021/acsami.6b01755. Epub 2016 Apr 29.

PMID:
27128771
20.

Nuclear envelope rupture and repair during cancer cell migration.

Denais CM, Gilbert RM, Isermann P, McGregor AL, te Lindert M, Weigelin B, Davidson PM, Friedl P, Wolf K, Lammerding J.

Science. 2016 Apr 15;352(6283):353-8. doi: 10.1126/science.aad7297. Epub 2016 Mar 24.

21.

Anti-CD137 monoclonal antibodies and adoptive T cell therapy: a perfect marriage?

Weigelin B, Bolaños E, Rodriguez-Ruiz ME, Martinez-Forero I, Friedl P, Melero I.

Cancer Immunol Immunother. 2016 May;65(5):493-7. doi: 10.1007/s00262-016-1818-5. Epub 2016 Mar 12.

PMID:
26970765
22.

Opposing Roles of JNK and p38 in Lymphangiogenesis in Melanoma.

Puujalka E, Heinz M, Hoesel B, Friedl P, Schweighofer B, Wenzina J, Pirker C, Schmid JA, Loewe R, Wagner EF, Berger W, Petzelbauer P.

J Invest Dermatol. 2016 May;136(5):967-77. doi: 10.1016/j.jid.2016.01.020. Epub 2016 Jan 30.

23.

Third harmonic generation microscopy of cells and tissue organization.

Weigelin B, Bakker GJ, Friedl P.

J Cell Sci. 2016 Jan 15;129(2):245-55. doi: 10.1242/jcs.152272. Epub 2016 Jan 7. Review.

24.

Examination of the foreign body response to biomaterials by nonlinear intravital microscopy.

Dondossola E, Holzapfel BM, Alexander S, Filippini S, Hutmacher DW, Friedl P.

Nat Biomed Eng. 2016;1. pii: 0007. doi: 10.1038/s41551-016-0007. Epub 2016 Dec 19.

25.

Collective cell migration: guidance principles and hierarchies.

Haeger A, Wolf K, Zegers MM, Friedl P.

Trends Cell Biol. 2015 Sep;25(9):556-66. doi: 10.1016/j.tcb.2015.06.003. Epub 2015 Jun 29. Review.

PMID:
26137890
26.

Translating Membrane Tension into Cytoskeletal Action by FBP17.

Zegers MM, Friedl P.

Dev Cell. 2015 Jun 22;33(6):628-30. doi: 10.1016/j.devcel.2015.06.006.

27.

Focusing and sustaining the antitumor CTL effector killer response by agonist anti-CD137 mAb.

Weigelin B, Bolaños E, Teijeira A, Martinez-Forero I, Labiano S, Azpilikueta A, Morales-Kastresana A, Quetglas JI, Wagena E, Sánchez-Paulete AR, Chen L, Friedl P, Melero I.

Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7551-6. doi: 10.1073/pnas.1506357112. Epub 2015 Jun 1.

28.

Yes-mediated phosphorylation of focal adhesion kinase at tyrosine 861 increases metastatic potential of prostate cancer cells.

Chatterji T, Varkaris AS, Parikh NU, Song JH, Cheng CJ, Schweppe RE, Alexander S, Davis JW, Troncoso P, Friedl P, Kuang J, Lin SH, Gallick GE.

Oncotarget. 2015 Apr 30;6(12):10175-94.

29.

A Swiss Army knife for CTLs.

Friedl P, Weigelin B.

Immunity. 2014 Dec 18;41(6):873-5. doi: 10.1016/j.immuni.2014.12.008.

30.

An open data ecosystem for cell migration research.

Masuzzo P, Martens L; 2014 Cell Migration Workshop Participants, Ampe C, Anderson KI, Barry J, De Wever O, Debeir O, Decaestecker C, Dolznig H, Friedl P, Gaggioli C, Geiger B, Goldberg IG, Horn E, Horwitz R, Kam Z, Le Dévédec SE, Vignjevic DM, Moore J, Olivo-Marin JC, Sahai E, Sansone SA, Sanz-Moreno V, Strömblad S, Swedlow J, Textor J, Van Troys M, Zantl R.

Trends Cell Biol. 2015 Feb;25(2):55-8. doi: 10.1016/j.tcb.2014.11.005. Epub 2014 Dec 5.

PMID:
25484346
31.

Directing collagen fibers using counter-rotating cone extrusion.

Hoogenkamp HR, Bakker GJ, Wolf L, Suurs P, Dunnewind B, Barbut S, Friedl P, van Kuppevelt TH, Daamen WF.

Acta Biomater. 2015 Jan;12:113-121. doi: 10.1016/j.actbio.2014.10.012. Epub 2014 Oct 16.

PMID:
25462525
32.

Plasticity of the actin cytoskeleton in response to extracellular matrix nanostructure and dimensionality.

Starke J, Wehrle-Haller B, Friedl P.

Biochem Soc Trans. 2014 Oct;42(5):1356-66. doi: 10.1042/BST20140139.

PMID:
25233415
33.

Rho GTPases in collective cell migration.

Zegers MM, Friedl P.

Small GTPases. 2014;5:e28997. doi: 10.4161/sgtp.28997. Epub 2014 May 9. Review.

34.

Cell jamming: collective invasion of mesenchymal tumor cells imposed by tissue confinement.

Haeger A, Krause M, Wolf K, Friedl P.

Biochim Biophys Acta. 2014 Aug;1840(8):2386-95. doi: 10.1016/j.bbagen.2014.03.020. Epub 2014 Apr 8.

PMID:
24721714
35.

Rho-directed forces in collective migration.

Friedl P, Wolf K, Zegers MM.

Nat Cell Biol. 2014 Mar;16(3):208-10. doi: 10.1038/ncb2923. Erratum in: Nat Cell Biol. 2014 Apr;16(4):383.

PMID:
24576897
36.

Cancer invasion and resistance.

Häger A, Alexander S, Friedl P.

EJC Suppl. 2013 Sep;11(2):291-3. doi: 10.1016/j.ejcsup.2013.07.055. Review. No abstract available.

37.

Preclinical intravital microscopy of the tumour-stroma interface: invasion, metastasis, and therapy response.

Alexander S, Weigelin B, Winkler F, Friedl P.

Curr Opin Cell Biol. 2013 Oct;25(5):659-71. doi: 10.1016/j.ceb.2013.07.001. Epub 2013 Jul 26. Review.

PMID:
23896198
38.

Mechanotransduction of mesenchymal melanoma cell invasion into 3D collagen lattices: filopod-mediated extension-relaxation cycles and force anisotropy.

Starke J, Maaser K, Wehrle-Haller B, Friedl P.

Exp Cell Res. 2013 Oct 1;319(16):2424-33. doi: 10.1016/j.yexcr.2013.04.003. Epub 2013 Jul 2.

PMID:
23830878
39.

Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force.

Wolf K, Te Lindert M, Krause M, Alexander S, Te Riet J, Willis AL, Hoffman RM, Figdor CG, Weiss SJ, Friedl P.

J Cell Biol. 2013 Jun 24;201(7):1069-84. doi: 10.1083/jcb.201210152.

40.

New dimensions in cell migration.

Friedl P, Sahai E, Weiss S, Yamada KM.

Nat Rev Mol Cell Biol. 2012 Nov;13(11):743-7. doi: 10.1038/nrm3459. Epub 2012 Oct 17. Review.

PMID:
23072889
41.

Classifying collective cancer cell invasion.

Friedl P, Locker J, Sahai E, Segall JE.

Nat Cell Biol. 2012 Aug;14(8):777-83. doi: 10.1038/ncb2548. Review.

PMID:
22854810
42.

Intravital third harmonic generation microscopy of collective melanoma cell invasion: Principles of interface guidance and microvesicle dynamics.

Weigelin B, Bakker GJ, Friedl P.

Intravital. 2012 Jul 1;1(1):32-43. doi: 10.4161/intv.21223. eCollection 2012.

43.

A large-scale (19)F MRI-based cell migration assay to optimize cell therapy.

Bonetto F, Srinivas M, Weigelin B, Cruz LJ, Heerschap A, Friedl P, Figdor CG, de Vries IJ.

NMR Biomed. 2012 Sep;25(9):1095-103. doi: 10.1002/nbm.2774. Epub 2012 Feb 7.

PMID:
22315137
44.

Fluorescence lifetime microscopy of tumor cell invasion, drug delivery, and cytotoxicity.

Bakker GJ, Andresen V, Hoffman RM, Friedl P.

Methods Enzymol. 2012;504:109-25. doi: 10.1016/B978-0-12-391857-4.00005-7. Review.

PMID:
22264531
45.

Twenty-third annual Pezcoller Symposium: engineering influences in cancer research.

Friedl P, Hubbell J, Livingston D, Mihich E.

Cancer Res. 2012 Feb 15;72(4):841-4. doi: 10.1158/0008-5472.CAN-11-3080. Epub 2012 Jan 11.

46.

Cancer invasion and resistance: interconnected processes of disease progression and therapy failure.

Alexander S, Friedl P.

Trends Mol Med. 2012 Jan;18(1):13-26. doi: 10.1016/j.molmed.2011.11.003. Epub 2011 Dec 15. Review.

PMID:
22177734
47.

Cancer invasion and the microenvironment: plasticity and reciprocity.

Friedl P, Alexander S.

Cell. 2011 Nov 23;147(5):992-1009. doi: 10.1016/j.cell.2011.11.016. Review.

48.

Extracellular matrix determinants of proteolytic and non-proteolytic cell migration.

Wolf K, Friedl P.

Trends Cell Biol. 2011 Dec;21(12):736-44. doi: 10.1016/j.tcb.2011.09.006. Epub 2011 Oct 27. Review.

PMID:
22036198
49.

Interstitial guidance of cancer invasion.

Gritsenko PG, Ilina O, Friedl P.

J Pathol. 2012 Jan;226(2):185-99. doi: 10.1002/path.3031. Review.

PMID:
22006671
50.

Effective and minimally painful surgery of pilonidal sinus - asymmetric transposition flap according to Dufourmentel.

Friedl PG, Rappold EM, Jäger C.

J Dtsch Dermatol Ges. 2011 Apr;9(4):333-5. doi: 10.1111/j.1610-0387.2011.07662.x. Epub 2011 Mar 3. English, German. No abstract available.

PMID:
21371259

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