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Items: 1 to 50 of 163

1.

Differential multivariable risk prediction of appropriate shock versus competing mortality - A prospective cohort study to estimate benefits from ICD therapy.

Bergau L, Willems R, Sprenkeler DJ, Fischer TH, Flevari P, Hasenfuß G, Katsaras D, Kirova A, Lehnart SE, Lüthje L, Röver C, Seegers J, Sossalla S, Dunnink A, Sritharan R, Tuinenburg AE, Vandenberk B, Vos MA, Wijers SC, Friede T, Zabel M.

Int J Cardiol. 2018 Jun 28. pii: S0167-5273(18)32262-9. doi: 10.1016/j.ijcard.2018.06.103. [Epub ahead of print]

2.

Reducing antibiotic use for uncomplicated urinary tract infection in general practice by treatment with uva-ursi (REGATTA) - a double-blind, randomized, controlled comparative effectiveness trial.

Afshar K, Fleischmann N, Schmiemann G, Bleidorn J, Hummers-Pradier E, Friede T, Wegscheider K, Moore M, Gágyor I.

BMC Complement Altern Med. 2018 Jul 3;18(1):203. doi: 10.1186/s12906-018-2266-x.

3.

Group sequential designs with robust semiparametric recurrent event models.

Mütze T, Glimm E, Schmidli H, Friede T.

Stat Methods Med Res. 2018 Jan 1:962280218780538. doi: 10.1177/0962280218780538. [Epub ahead of print]

PMID:
29890892
4.

Robustness of testing procedures for confirmatory subpopulation analyses based on a continuous biomarker.

Graf AC, Wassmer G, Friede T, Gera RG, Posch M.

Stat Methods Med Res. 2018 Jan 1:962280218777538. doi: 10.1177/0962280218777538. [Epub ahead of print]

PMID:
29888651
5.

Group sequential designs for negative binomial outcomes.

Mütze T, Glimm E, Schmidli H, Friede T.

Stat Methods Med Res. 2018 Jan 1:962280218773115. doi: 10.1177/0962280218773115. [Epub ahead of print]

PMID:
29770729
6.

Randomised controlled trial of a self-guided online fatigue intervention in multiple sclerosis.

Pöttgen J, Moss-Morris R, Wendebourg JM, Feddersen L, Lau S, Köpke S, Meyer B, Friede T, Penner IK, Heesen C, Gold SM.

J Neurol Neurosurg Psychiatry. 2018 Mar 16. pii: jnnp-2017-317463. doi: 10.1136/jnnp-2017-317463. [Epub ahead of print]

PMID:
29549193
7.

Methods for evidence synthesis in the case of very few studies.

Bender R, Friede T, Koch A, Kuss O, Schlattmann P, Schwarzer G, Skipka G.

Res Synth Methods. 2018 Mar 5. doi: 10.1002/jrsm.1297. [Epub ahead of print]

PMID:
29504289
8.

dfpk: An R-package for Bayesian dose-finding designs using pharmacokinetics (PK) for phase I clinical trials.

Toumazi A, Comets E, Alberti C, Friede T, Lentz F, Stallard N, Zohar S, Ursino M.

Comput Methods Programs Biomed. 2018 Apr;157:163-177. doi: 10.1016/j.cmpb.2018.01.023. Epub 2018 Jan 31.

9.

Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: results from the German prospective, multicentre FITT-STEMI trial.

Scholz KH, Maier SKG, Maier LS, Lengenfelder B, Jacobshagen C, Jung J, Fleischmann C, Werner GS, Olbrich HG, Ott R, Mudra H, Seidl K, Schulze PC, Weiss C, Haimerl J, Friede T, Meyer T.

Eur Heart J. 2018 Apr 1;39(13):1065-1074. doi: 10.1093/eurheartj/ehy004.

10.

Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis.

Stork L, Ellenberger D, Beißbarth T, Friede T, Lucchinetti CF, Brück W, Metz I.

JAMA Neurol. 2018 Apr 1;75(4):428-435. doi: 10.1001/jamaneurol.2017.4842.

PMID:
29404583
11.

Reclassifying Acute Respiratory Distress Syndrome.

Maiolo G, Collino F, Vasques F, Rapetti F, Tonetti T, Romitti F, Cressoni M, Chiumello D, Moerer O, Herrmann P, Friede T, Quintel M, Gattinoni L.

Am J Respir Crit Care Med. 2018 Jun 15;197(12):1586-1595. doi: 10.1164/rccm.201709-1804OC.

PMID:
29345967
12.

Clinical trials with nested subgroups: Analysis, sample size determination and internal pilot studies.

Placzek M, Friede T.

Stat Methods Med Res. 2017 Jan 1:962280217696116. doi: 10.1177/0962280217696116. [Epub ahead of print]

PMID:
29298604
13.

Treatment of fatigue in amyotrophic lateral sclerosis/motor neuron disease.

Gibbons C, Pagnini F, Friede T, Young CA.

Cochrane Database Syst Rev. 2018 Jan 2;1:CD011005. doi: 10.1002/14651858.CD011005.pub2. Review.

PMID:
29293261
14.

A standardised frankincense extract reduces disease activity in relapsing-remitting multiple sclerosis (the SABA phase IIa trial).

Stürner KH, Stellmann JP, Dörr J, Paul F, Friede T, Schammler S, Reinhardt S, Gellissen S, Weissflog G, Faizy TD, Werz O, Fleischer S, Vaas LAI, Herrmann F, Pless O, Martin R, Heesen C.

J Neurol Neurosurg Psychiatry. 2018 Apr;89(4):330-338. doi: 10.1136/jnnp-2017-317101. Epub 2017 Dec 16.

PMID:
29248894
15.

A design-by-treatment interaction model for network meta-analysis and meta-regression with integrated nested Laplace approximations.

Günhan BK, Friede T, Held L.

Res Synth Methods. 2018 Jun;9(2):179-194. doi: 10.1002/jrsm.1285. Epub 2018 Jan 16.

16.

Sample size re-estimation incorporating prior information on a nuisance parameter.

Mütze T, Schmidli H, Friede T.

Pharm Stat. 2018 Mar;17(2):126-143. doi: 10.1002/pst.1837. Epub 2017 Nov 27.

PMID:
29181869
17.

Echocardiographic Estimation of Mean Pulmonary Artery Pressure: A Comparison of Different Approaches to Assign the Likelihood of Pulmonary Hypertension.

Hellenkamp K, Unsöld B, Mushemi-Blake S, Shah AM, Friede T, Hasenfuß G, Seidler T.

J Am Soc Echocardiogr. 2018 Jan;31(1):89-98. doi: 10.1016/j.echo.2017.09.009. Epub 2017 Nov 23.

PMID:
29174340
18.

Predictors of mortality and ICD shock therapy in primary prophylactic ICD patients-A systematic review and meta-analysis.

Bergau L, Tichelbäcker T, Kessel B, Lüthje L, Fischer TH, Friede T, Zabel M.

PLoS One. 2017 Oct 17;12(10):e0186387. doi: 10.1371/journal.pone.0186387. eCollection 2017. Review.

19.

Sex differences in outcomes of primary prevention implantable cardioverter-defibrillator therapy: combined registry data from eleven European countries.

Sticherling C, Arendacka B, Svendsen JH, Wijers S, Friede T, Stockinger J, Dommasch M, Merkely B, Willems R, Lubinski A, Scharfe M, Braunschweig F, Svetlosak M, Zürn CS, Huikuri H, Flevari P, Lund-Andersen C, Schaer BA, Tuinenburg AE, Bergau L, Schmidt G, Szeplaki G, Vandenberk B, Kowalczyk E, Eick C, Juntilla J, Conen D, Zabel M; EU-CERT-ICD Investigators.

Europace. 2018 Jun 1;20(6):963-970. doi: 10.1093/europace/eux176.

20.

Patient-reported outcomes and survival in multiple sclerosis: A 10-year retrospective cohort study using the Multiple Sclerosis Impact Scale-29.

Raffel J, Wallace A, Gveric D, Reynolds R, Friede T, Nicholas R.

PLoS Med. 2017 Jul 10;14(7):e1002346. doi: 10.1371/journal.pmed.1002346. eCollection 2017 Jul.

21.

Modelling and sample size reestimation for longitudinal count data with incomplete follow up.

Asendorf T, Henderson R, Schmidli H, Friede T.

Stat Methods Med Res. 2017 Jan 1:962280217715664. doi: 10.1177/0962280217715664. [Epub ahead of print]

PMID:
28633609
22.

Blinded sample size re-estimation in three-arm trials with 'gold standard' design.

Mütze T, Friede T.

Stat Med. 2017 Oct 15;36(23):3636-3653. doi: 10.1002/sim.7356. Epub 2017 Jun 12.

PMID:
28608469
23.

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response.

Stellmann JP, Krumbholz M, Friede T, Gahlen A, Borisow N, Fischer K, Hellwig K, Pache F, Ruprecht K, Havla J, Kümpfel T, Aktas O, Hartung HP, Ringelstein M, Geis C, Kleinschnitz C, Berthele A, Hemmer B, Angstwurm K, Young KL, Schuster S, Stangel M, Lauda F, Tumani H, Mayer C, Zeltner L, Ziemann U, Linker RA, Schwab M, Marziniak M, Then Bergh F, Hofstadt-van Oy U, Neuhaus O, Zettl U, Faiss J, Wildemann B, Paul F, Jarius S, Trebst C, Kleiter I; NEMOS (Neuromyelitis Optica Study Group).

J Neurol Neurosurg Psychiatry. 2017 Aug;88(8):639-647. doi: 10.1136/jnnp-2017-315603. Epub 2017 Jun 1.

24.

Toward evidence-based diagnosis of myocarditis in children and adolescents: Rationale, design, and first baseline data of MYKKE, a multicenter registry and study platform.

Messroghli DR, Pickardt T, Fischer M, Opgen-Rhein B, Papakostas K, Böcker D, Jakob A, Khalil M, Mueller GC, Schmidt F, Kaestner M, Udink Ten Cate FEA, Wagner R, Ruf B, Kiski D, Wiegand G, Degener F, Bauer UMM, Friede T, Schubert S; MYKKE Consortium.

Am Heart J. 2017 May;187:133-144. doi: 10.1016/j.ahj.2017.02.027. Epub 2017 Feb 24.

PMID:
28454797
25.

Pharmacological Approaches to the Management of Secondary Progressive Multiple Sclerosis.

Nandoskar A, Raffel J, Scalfari AS, Friede T, Nicholas RS.

Drugs. 2017 May;77(8):885-910. doi: 10.1007/s40265-017-0726-0. Review.

PMID:
28429241
26.

Control conditions for randomised trials of behavioural interventions in psychiatry: a decision framework.

Gold SM, Enck P, Hasselmann H, Friede T, Hegerl U, Mohr DC, Otte C.

Lancet Psychiatry. 2017 Sep;4(9):725-732. doi: 10.1016/S2215-0366(17)30153-0. Epub 2017 Apr 7. Review.

PMID:
28396067
27.

Using phase II data for the analysis of phase III studies: An application in rare diseases.

Wandel S, Neuenschwander B, Röver C, Friede T.

Clin Trials. 2017 Jun;14(3):277-285. doi: 10.1177/1740774517699409. Epub 2017 Apr 7.

28.

Dose-finding methods for Phase I clinical trials using pharmacokinetics in small populations.

Ursino M, Zohar S, Lentz F, Alberti C, Friede T, Stallard N, Comets E.

Biom J. 2017 Jul;59(4):804-825. doi: 10.1002/bimj.201600084. Epub 2017 Mar 21.

29.

T-wave loop area from a pre-implant 12-lead ECG is associated with appropriate ICD shocks.

Seegers J, Hnatkova K, Friede T, Malik M, Zabel M.

PLoS One. 2017 Mar 14;12(3):e0173868. doi: 10.1371/journal.pone.0173868. eCollection 2017.

30.

Independent academic Data Monitoring Committees for clinical trials in cardiovascular and cardiometabolic diseases.

Filippatos GS, de Graeff P, Bax JJ, Borg JJ, Cleland JG, Dargie HJ, Flather M, Ford I, Friede T, Greenberg B, Henon-Goburdhun C, Holcomb R, Horst B, Lekakis J, Mueller-Velten G, Papavassiliou AG, Prasad K, Rosano GM, Severin T, Sherman W, Stough WG, Swedberg K, Tavazzi L, Tousoulis D, Vardas P, Ruschitzka F, Anker SD.

Eur J Heart Fail. 2017 Apr;19(4):449-456. doi: 10.1002/ejhf.761. Epub 2017 Mar 8. Review.

31.

Do we consent to rules of consent and confidentiality?

Wegscheider K, Friede T.

Biom J. 2017 Mar;59(2):235-239. doi: 10.1002/bimj.201600150.

PMID:
28267282
32.

Blinded versus unblinded estimation of a correlation coefficient to inform interim design adaptations.

Kunz CU, Stallard N, Parsons N, Todd S, Friede T.

Biom J. 2017 Mar;59(2):344-357. doi: 10.1002/bimj.201500233. Epub 2016 Nov 25.

33.

A studentized permutation test for three-arm trials in the 'gold standard' design.

Mütze T, Konietschke F, Munk A, Friede T.

Stat Med. 2017 Mar 15;36(6):883-898. doi: 10.1002/sim.7176. Epub 2016 Nov 16.

PMID:
27859506
34.

Doxycycline in early CJD: a double-blinded randomised phase II and observational study.

Varges D, Manthey H, Heinemann U, Ponto C, Schmitz M, Schulz-Schaeffer WJ, Krasnianski A, Breithaupt M, Fincke F, Kramer K, Friede T, Zerr I.

J Neurol Neurosurg Psychiatry. 2017 Feb;88(2):119-125. doi: 10.1136/jnnp-2016-313541. Epub 2016 Nov 2.

35.

Results of medial patellofemoral ligament reconstruction compared with trochleoplasty plus individual extensor apparatus balancing in patellar instability caused by severe trochlear dysplasia: a systematic review and meta-analysis.

Balcarek P, Rehn S, Howells NR, Eldridge JD, Kita K, Dejour D, Nelitz M, Banke IJ, Lambrecht D, Harden M, Friede T.

Knee Surg Sports Traumatol Arthrosc. 2017 Dec;25(12):3869-3877. doi: 10.1007/s00167-016-4365-x. Epub 2016 Oct 27. Review.

PMID:
27796419
36.

Evaluation of dysphagia by novel real-time MRI.

Olthoff A, Carstens PO, Zhang S, von Fintel E, Friede T, Lotz J, Frahm J, Schmidt J.

Neurology. 2016 Nov 15;87(20):2132-2138. Epub 2016 Oct 21.

PMID:
27770070
37.

Meta-analysis of two studies in the presence of heterogeneity with applications in rare diseases.

Friede T, Röver C, Wandel S, Neuenschwander B.

Biom J. 2017 Jul;59(4):658-671. doi: 10.1002/bimj.201500236. Epub 2016 Oct 18.

38.

Gender Differences in Appropriate Shocks and Mortality among Patients with Primary Prophylactic Implantable Cardioverter-Defibrillators: Systematic Review and Meta-Analysis.

Conen D, Arendacká B, Röver C, Bergau L, Munoz P, Wijers S, Sticherling C, Zabel M, Friede T.

PLoS One. 2016 Sep 12;11(9):e0162756. doi: 10.1371/journal.pone.0162756. eCollection 2016. Review.

39.

Identifying back pain subgroups: developing and applying approaches using individual patient data collected within clinical trials.

Patel S, Hee SW, Mistry D, Jordan J, Brown S, Dritsaki M, Ellard DR, Friede T, Lamb SE, Lord J, Madan J, Morris T, Stallard N, Tysall C, Willis A, Underwood M; the Repository Group.

Southampton (UK): NIHR Journals Library; 2016 Jul.

40.

EFSPI/PSI working group on data sharing: accessing and working with pharmaceutical clinical trial patient level datasets - a primer for academic researchers.

Sudlow R, Branson J, Friede T, Morgan D, Whately-Smith C.

BMC Med Res Methodol. 2016 Jul 8;16 Suppl 1:73. doi: 10.1186/s12874-016-0171-x.

41.

An Unconditional Test for Change Point Detection in Binary Sequences with Applications to Clinical Registries.

Ellenberger D, Friede T.

Methods Inf Med. 2016 Aug 5;55(4):367-72. doi: 10.3414/ME15-02-0020. Epub 2016 Jul 13.

PMID:
27406195
42.

Meta-analysis of few small studies in orphan diseases.

Friede T, Röver C, Wandel S, Neuenschwander B.

Res Synth Methods. 2017 Mar;8(1):79-91. doi: 10.1002/jrsm.1217. Epub 2016 Jun 30.

43.

Back schools for the treatment of chronic low back pain: possibility of benefit but no convincing evidence after 47 years of research-systematic review and meta-analysis.

Straube S, Harden M, Schröder H, Arendacka B, Fan X, Moore RA, Friede T.

Pain. 2016 Oct;157(10):2160-72. doi: 10.1097/j.pain.0000000000000640. Review.

44.

The N-MOmentum trial: Building momentum to advance trial methodology in a rare disease.

Chataway J, Friede T.

Mult Scler. 2016 Jun;22(7):852-3. doi: 10.1177/1352458516643399. No abstract available.

PMID:
27256900
45.

Advances and unmet needs in genetic, basic and clinical science in Alport syndrome: report from the 2015 International Workshop on Alport Syndrome.

Gross O, Kashtan CE, Rheault MN, Flinter F, Savige J, Miner JH, Torra R, Ars E, Deltas C, Savva I, Perin L, Renieri A, Ariani F, Mari F, Baigent C, Judge P, Knebelman B, Heidet L, Lagas S, Blatt D, Ding J, Zhang Y, Gale DP, Prunotto M, Xue Y, Schachter AD, Morton LCG, Blem J, Huang M, Liu S, Vallee S, Renault D, Schifter J, Skelding J, Gear S, Friede T, Turner AN, Lennon R.

Nephrol Dial Transplant. 2017 Jun 1;32(6):916-924. doi: 10.1093/ndt/gfw095.

46.

Prediction of Appropriate Shocks Using 24-Hour Holter Variables and T-Wave Alternans After First Implantable Cardioverter-Defibrillator Implantation in Patients With Ischemic or Nonischemic Cardiomyopathy.

Seegers J, Bergau L, Expósito PM, Bauer A, Fischer TH, Lüthje L, Hasenfuß G, Friede T, Zabel M.

Am J Cardiol. 2016 Jul 1;118(1):86-94. doi: 10.1016/j.amjcard.2016.04.016. Epub 2016 Apr 22.

47.

Monitoring of 30 marker candidates in early Parkinson disease as progression markers.

Mollenhauer B, Zimmermann J, Sixel-Döring F, Focke NK, Wicke T, Ebentheuer J, Schaumburg M, Lang E, Trautmann E, Zetterberg H, Taylor P, Friede T, Trenkwalder C; DeNoPa Study Group.

Neurology. 2016 Jul 12;87(2):168-77. doi: 10.1212/WNL.0000000000002651. Epub 2016 May 6.

48.

Peripheral Nerve Dysfunction in Middle-Aged Subjects Born with Thalidomide Embryopathy.

Nicotra A, Newman C, Johnson M, Eremin O, Friede T, Malik O, Nicholas R.

PLoS One. 2016 Apr 21;11(4):e0152902. doi: 10.1371/journal.pone.0152902. eCollection 2016.

49.

Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions.

Unkel S, Röver C, Stallard N, Benda N, Posch M, Zohar S, Friede T.

Orphanet J Rare Dis. 2016 Feb 20;11:16. doi: 10.1186/s13023-016-0402-6. Review.

50.

Serum peptide reactivities may distinguish neuromyelitis optica subgroups and multiple sclerosis.

Metz I, Beißbarth T, Ellenberger D, Pache F, Stork L, Ringelstein M, Aktas O, Jarius S, Wildemann B, Dihazi H, Friede T, Brück W, Ruprecht K, Paul F.

Neurol Neuroimmunol Neuroinflamm. 2016 Feb 2;3(2):e204. doi: 10.1212/NXI.0000000000000204. eCollection 2016 Apr.

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