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Items: 15

1.

Gamma-H2AX immunofluorescence for the detection of tissue-specific genotoxicity in vivo.

Plappert-Helbig U, Libertini S, Frieauff W, Theil D, Martus HJ.

Environ Mol Mutagen. 2018 Oct 11. doi: 10.1002/em.22238. [Epub ahead of print]

PMID:
30307065
2.

The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.

Neumann U, Ufer M, Jacobson LH, Rouzade-Dominguez ML, Huledal G, Kolly C, Lüönd RM, Machauer R, Veenstra SJ, Hurth K, Rueeger H, Tintelnot-Blomley M, Staufenbiel M, Shimshek DR, Perrot L, Frieauff W, Dubost V, Schiller H, Vogg B, Beltz K, Avrameas A, Kretz S, Pezous N, Rondeau JM, Beckmann N, Hartmann A, Vormfelde S, David OJ, Galli B, Ramos R, Graf A, Lopez Lopez C.

EMBO Mol Med. 2018 Sep 17. pii: e9316. doi: 10.15252/emmm.201809316. [Epub ahead of print]

3.

Brain region-specific enhancement of remyelination and prevention of demyelination by the CSF1R kinase inhibitor BLZ945.

Beckmann N, Giorgetti E, Neuhaus A, Zurbruegg S, Accart N, Smith P, Perdoux J, Perrot L, Nash M, Desrayaud S, Wipfli P, Frieauff W, Shimshek DR.

Acta Neuropathol Commun. 2018 Feb 15;6(1):9. doi: 10.1186/s40478-018-0510-8.

4.

Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor-treated APP transgenic mice.

Beckmann N, Doelemeyer A, Zurbruegg S, Bigot K, Theil D, Frieauff W, Kolly C, Moulin P, Neddermann D, Kreutzer R, Perrot L, Brzak I, Jacobson LH, Staufenbiel M, Neumann U, Shimshek DR.

Neurobiol Aging. 2016 Sep;45:50-60. doi: 10.1016/j.neurobiolaging.2016.05.009. Epub 2016 May 17.

5.

A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-β and neuroinflammation in APP transgenic mice.

Neumann U, Rueeger H, Machauer R, Veenstra SJ, Lueoend RM, Tintelnot-Blomley M, Laue G, Beltz K, Vogg B, Schmid P, Frieauff W, Shimshek DR, Staufenbiel M, Jacobson LH.

Mol Neurodegener. 2015 Sep 3;10:44. doi: 10.1186/s13024-015-0033-8.

6.

Clinical classification of cancer cachexia: phenotypic correlates in human skeletal muscle.

Johns N, Hatakeyama S, Stephens NA, Degen M, Degen S, Frieauff W, Lambert C, Ross JA, Roubenoff R, Glass DJ, Jacobi C, Fearon KC.

PLoS One. 2014 Jan 3;9(1):e83618. doi: 10.1371/journal.pone.0083618. eCollection 2014.

7.

Automatic analysis of the micronucleus test in primary human lymphocytes using image analysis.

Frieauff W, Martus HJ, Suter W, Elhajouji A.

Mutagenesis. 2013 Jan;28(1):15-23. doi: 10.1093/mutage/ges047. Epub 2012 Oct 5.

PMID:
23042049
8.

High-content micronucleus assay in genotoxicity profiling: initial-stage development and some applications in the investigative/lead-finding studies in drug discovery.

Mondal MS, Gabriels J, McGinnis C, Magnifico M, Marsilje TH, Urban L, Collis A, Bojanic D, Biller SA, Frieauff W, Martus HJ, Suter W, Bentley P.

Toxicol Sci. 2010 Nov;118(1):71-85. doi: 10.1093/toxsci/kfq181. Epub 2010 Jul 14.

PMID:
20631060
9.

Structure-activity considerations and in vitro approaches to assess the genotoxicity of 19 methane-, benzene- and toluenesulfonic acid esters.

Glowienke S, Frieauff W, Allmendinger T, Martus HJ, Suter W, Mueller L.

Mutat Res. 2005 Mar 7;581(1-2):23-34. Epub 2004 Dec 21.

PMID:
15725602
10.

Use of the alkaline comet assay for industrial genotoxicity screening: comparative investigation with the micronucleus test.

Hartmann A, Elhajouji A, Kiskinis E, Poetter F, Martus H, Fjällman A, Frieauff W, Suter W.

Food Chem Toxicol. 2001 Aug;39(8):843-58.

PMID:
11434992
11.

Automatic analysis of slides processed in the Comet assay.

Frieauff W, Hartmann A, Suter W.

Mutagenesis. 2001 Mar;16(2):133-7.

PMID:
11230555
12.

In vitro models to study mechanisms involved in cyclosporine A-mediated glomerular contraction.

L'Azou B, Medina J, Frieauff W, Cordier A, Cambar J, Wolf A.

Arch Toxicol. 1999 Aug;73(6):337-45.

PMID:
10447561
13.

Automatic analysis of the in vitro micronucleus test on V79 cells.

Frieauff W, Pötter-Locher F, Cordier A, Suter W.

Mutat Res. 1998 Feb 23;413(1):57-68.

PMID:
9602859
14.

Technical aspects of automatic micronucleus analysis in rodent bone marrow assays.

Frieauff W, Romagna F.

Cell Biol Toxicol. 1994 Dec;10(5-6):283-9.

PMID:
7697486
15.

Role of reactive oxygen formation in the cyclosporin-A-mediated impairment of renal functions.

Wolf A, Clemann N, Frieauff W, Ryffel B, Cordier A.

Transplant Proc. 1994 Oct;26(5):2902-7. No abstract available.

PMID:
7940917

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