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Items: 18

1.

Transcriptome-wide analysis of filarial extract-primed human monocytes reveal changes in LPS-induced PTX3 expression levels.

Buerfent BC, Gölz L, Hofmann A, Rühl H, Stamminger W, Fricker N, Hess T, Oldenburg J, Nöthen MM, Schumacher J, Hübner MP, Hoerauf A.

Sci Rep. 2019 Feb 22;9(1):2562. doi: 10.1038/s41598-019-38985-x.

2.

Insights into Male Androgenetic Alopecia: Differential Gene Expression Profiling of Plucked Hair Follicles and Integration with Genetic Data.

Hochfeld LM, Keller A, Anhalt T, Fricker N; Meta-analysis for Androgenetic Alopecia Novel determinants (MAAN) Consortium, Nöthen MM, Heilmann-Heimbach S.

J Invest Dermatol. 2019 Jan;139(1):235-238. doi: 10.1016/j.jid.2018.06.182. Epub 2018 Jul 21. No abstract available.

3.

Nonsyndromic cleft palate: An association study at GWAS candidate loci in a multiethnic sample.

Ishorst N, Francheschelli P, Böhmer AC, Khan MFJ, Heilmann-Heimbach S, Fricker N, Little J, Steegers-Theunissen RPM, Peterlin B, Nowak S, Martini M, Kruse T, Dunsche A, Kreusch T, Gölz L, Aldhorae K, Halboub E, Reutter H, Mossey P, Nöthen MM, Rubini M, Ludwig KU, Knapp M, Mangold E.

Birth Defects Res. 2018 Jun 1;110(10):871-882. doi: 10.1002/bdr2.1213. Epub 2018 Mar 2.

PMID:
29498243
4.

Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus.

Schulz H, Ruppert AK, Herms S, Wolf C, Mirza-Schreiber N, Stegle O, Czamara D, Forstner AJ, Sivalingam S, Schoch S, Moebus S, Pütz B, Hillmer A, Fricker N, Vatter H, Müller-Myhsok B, Nöthen MM, Becker AJ, Hoffmann P, Sander T, Cichon S.

Nat Commun. 2017 Nov 15;8(1):1511. doi: 10.1038/s41467-017-01818-4.

5.

Genetic regulatory effects modified by immune activation contribute to autoimmune disease associations.

Kim-Hellmuth S, Bechheim M, Pütz B, Mohammadi P, Nédélec Y, Giangreco N, Becker J, Kaiser V, Fricker N, Beier E, Boor P, Castel SE, Nöthen MM, Barreiro LB, Pickrell JK, Müller-Myhsok B, Lappalainen T, Schumacher J, Hornung V.

Nat Commun. 2017 Aug 16;8(1):266. doi: 10.1038/s41467-017-00366-1.

6.

Expression profiling and bioinformatic analyses suggest new target genes and pathways for human hair follicle related microRNAs.

Hochfeld LM, Anhalt T, Reinbold CS, Herrera-Rivero M, Fricker N, Nöthen MM, Heilmann-Heimbach S.

BMC Dermatol. 2017 Feb 22;17(1):3. doi: 10.1186/s12895-017-0054-9.

7.

Genome-wide transcriptome induced by nickel in human monocytes.

Gölz L, Buerfent BC, Hofmann A, Rühl H, Fricker N, Stamminger W, Oldenburg J, Deschner J, Hoerauf A, Nöthen MM, Schumacher J, Hübner MP, Jäger A.

Acta Biomater. 2016 Oct 1;43:369-382. doi: 10.1016/j.actbio.2016.07.047. Epub 2016 Jul 28.

PMID:
27477848
8.

Genome-wide transcriptome induced by Porphyromonas gingivalis LPS supports the notion of host-derived periodontal destruction and its association with systemic diseases.

Gölz L, Buerfent BC, Hofmann A, Hübner MP, Rühl H, Fricker N, Schmidt D, Johannes O, Jepsen S, Deschner J, Hoerauf A, Nöthen MM, Schumacher J, Jäger A.

Innate Immun. 2016 Jan;22(1):72-84. doi: 10.1177/1753425915616685. Epub 2015 Nov 24.

PMID:
26608307
9.

Investigation of the role of TCF4 rare sequence variants in schizophrenia.

Basmanav FB, Forstner AJ, Fier H, Herms S, Meier S, Degenhardt F, Hoffmann P, Barth S, Fricker N, Strohmaier J, Witt SH, Ludwig M, Schmael C, Moebus S, Maier W, Mössner R, Rujescu D, Rietschel M, Lange C, Nöthen MM, Cichon S.

Am J Med Genet B Neuropsychiatr Genet. 2015 Jul;168B(5):354-62. doi: 10.1002/ajmg.b.32318. Epub 2015 May 22.

PMID:
26010163
10.

Characterizing the genetic basis of innate immune response in TLR4-activated human monocytes.

Kim S, Becker J, Bechheim M, Kaiser V, Noursadeghi M, Fricker N, Beier E, Klaschik S, Boor P, Hess T, Hofmann A, Holdenrieder S, Wendland JR, Fröhlich H, Hartmann G, Nöthen MM, Müller-Myhsok B, Pütz B, Hornung V, Schumacher J.

Nat Commun. 2014 Oct 20;5:5236. doi: 10.1038/ncomms6236.

PMID:
25327457
11.

Nonsyndromic cleft lip with or without cleft palate: Increased burden of rare variants within Gremlin-1, a component of the bone morphogenetic protein 4 pathway.

Al Chawa T, Ludwig KU, Fier H, Pötzsch B, Reich RH, Schmidt G, Braumann B, Daratsianos N, Böhmer AC, Schuencke H, Alblas M, Fricker N, Hoffmann P, Knapp M, Lange C, Nöthen MM, Mangold E.

Birth Defects Res A Clin Mol Teratol. 2014 Jun;100(6):493-8. doi: 10.1002/bdra.23244. Epub 2014 Apr 7.

PMID:
24706492
12.

Androgenetic alopecia: identification of four genetic risk loci and evidence for the contribution of WNT signaling to its etiology.

Heilmann S, Kiefer AK, Fricker N, Drichel D, Hillmer AM, Herold C, Tung JY, Eriksson N, Redler S, Betz RC, Li R, Kárason A, Nyholt DR, Song K, Vermeulen SH, Kanoni S, Dedoussis G, Martin NG, Kiemeney LA, Mooser V, Stefansson K, Richards JB, Becker T, Brockschmidt FF, Hinds DA, Nöthen MM.

J Invest Dermatol. 2013 Jun;133(6):1489-96. doi: 10.1038/jid.2013.43. Epub 2013 Jan 28.

13.

Resequencing of VAX1 in patients with nonsyndromic cleft lip with or without cleft palate.

Nasser E, Mangold E, Tradowsky DC, Fier H, Becker J, Boehmer AC, Herberz R, Fricker N, Barth S, Wahle P, Nowak S, Reutter H, Reich RH, Lauster C, Braumann B, Kreusch T, Hemprich A, Pötzsch B, Hoffmann P, Kramer FJ, Knapp M, Lange C, Nöthen MM, Ludwig KU.

Birth Defects Res A Clin Mol Teratol. 2012 Nov;94(11):925-33. doi: 10.1002/bdra.23078. Epub 2012 Oct 18.

PMID:
23081944
14.

Stoichiometry of the CD95 death-inducing signaling complex: experimental and modeling evidence for a death effector domain chain model.

Schleich K, Warnken U, Fricker N, Oztürk S, Richter P, Kammerer K, Schnölzer M, Krammer PH, Lavrik IN.

Mol Cell. 2012 Jul 27;47(2):306-19. doi: 10.1016/j.molcel.2012.05.006. Epub 2012 Jun 7.

15.

Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation.

Kober AM, Legewie S, Pforr C, Fricker N, Eils R, Krammer PH, Lavrik IN.

Cell Death Dis. 2011 Oct 6;2:e212. doi: 10.1038/cddis.2011.93.

16.

Model-based dissection of CD95 signaling dynamics reveals both a pro- and antiapoptotic role of c-FLIPL.

Fricker N, Beaudouin J, Richter P, Eils R, Krammer PH, Lavrik IN.

J Cell Biol. 2010 Aug 9;190(3):377-89. doi: 10.1083/jcb.201002060.

17.

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells.

Neumann L, Pforr C, Beaudouin J, Pappa A, Fricker N, Krammer PH, Lavrik IN, Eils R.

Mol Syst Biol. 2010;6:352. doi: 10.1038/msb.2010.6. Epub 2010 Mar 9.

18.

Understanding apoptosis by systems biology approaches.

Lavrik IN, Eils R, Fricker N, Pforr C, Krammer PH.

Mol Biosyst. 2009 Oct;5(10):1105-11. doi: 10.1039/b905129p. Epub 2009 Aug 3. Review.

PMID:
19756299

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