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Items: 1 to 50 of 189

1.

Effect of methadone and acepromazine premedication on tear production in dogs.

Volk HA, West E, Linn-Pearl RN, Fricker GV, Panti A, Gould DJ.

Vet Rec Open. 2018 Dec 5;5(1):e000298. doi: 10.1136/vetreco-2018-000298. eCollection 2018.

2.

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging.

Schirrmacher R, Bailey JJ, Mossine AV, Scott PJH, Kaiser L, Bartenstein P, Lindner S, Kaplan DR, Kostikov A, Fricker G, Mahringer A, Rosa-Neto P, Schirrmacher E, Wängler C, Wängler B, Thiel A, Soucy JP, Bernard-Gauthier V.

Pharmaceuticals (Basel). 2019 Jan 3;12(1). pii: E7. doi: 10.3390/ph12010007. Review.

3.

Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo.

Zaremba A, Helm F, Fricker G.

Mol Pharm. 2018 Nov 29. doi: 10.1021/acs.molpharmaceut.8b00987. [Epub ahead of print]

PMID:
30422662
4.
5.

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

Vall-Sagarra A, Litau S, Decristoforo C, Wängler B, Schirrmacher R, Fricker G, Wängler C.

Pharmaceuticals (Basel). 2018 Jul 4;11(3). pii: E65. doi: 10.3390/ph11030065.

6.

Circulating Troponin I Level in Patients with Acute Ischemic Stroke.

VanHouten J, Fricker G, Collins B, Bhatia R, Ellis C, Schrag M.

Curr Neurol Neurosci Rep. 2018 Apr 20;18(6):32. doi: 10.1007/s11910-018-0842-6. Review.

PMID:
29679162
7.

Practice Patterns of Providers for the Management of Staphylococcus aureus Bacteremia in Children: Results of an Emerging Infections Network Survey.

Wood JB, Fricker GP, Beekmann SE, Polgreen P, Buddy Creech C.

J Pediatric Infect Dis Soc. 2018 Aug 17;7(3):e152-e155. doi: 10.1093/jpids/piy022.

PMID:
29534244
8.

In Vitro and In Situ Absorption and Metabolism of Sesquiterpenes from Petasites hybridus Extracts.

Disch L, Forsch K, Siewert B, Drewe J, Fricker G.

Planta Med. 2018 Jul;84(11):795-805. doi: 10.1055/s-0044-100401. Epub 2018 Jan 16.

PMID:
29341029
9.

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2018 Jan 12;15(1):3. doi: 10.1186/s12987-017-0086-x.

10.

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging.

Bernard-Gauthier V, Mossine AV, Mahringer A, Aliaga A, Bailey JJ, Shao X, Stauff J, Arteaga J, Sherman P, Grand'Maison M, Rochon PL, Wängler B, Wängler C, Bartenstein P, Kostikov A, Kaplan DR, Fricker G, Rosa-Neto P, Scott PJH, Schirrmacher R.

J Med Chem. 2018 Feb 22;61(4):1737-1743. doi: 10.1021/acs.jmedchem.7b01607. Epub 2018 Jan 5.

PMID:
29257860
11.

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors.

Prause M, Niedermoser S, Wängler C, Decristoforo C, Seibold U, Riester S, Taguchi T, Schirrmacher R, Fricker G, Wängler B.

Nucl Med Biol. 2018 Feb;57:1-11. doi: 10.1016/j.nucmedbio.2017.11.004. Epub 2017 Nov 17.

PMID:
29175467
12.

A Case of a 4-Year-Old Female with a Primary Spinal Malignancy Presenting with Froin's Syndrome.

Hale AT, Fricker GP, Crook TW.

Pediatr Neurosurg. 2018;53(1):64-68. doi: 10.1159/000481514. Epub 2017 Nov 2.

PMID:
29131102
13.

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2017 Nov 7;14(1):31. doi: 10.1186/s12987-017-0079-9. Erratum in: Fluids Barriers CNS. 2018 Jan 12;15(1):3.

14.

Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus).

Zaremba A, Miller DS, Fricker G.

Toxicol Appl Pharmacol. 2017 Nov 1;334:88-99. doi: 10.1016/j.taap.2017.09.001. Epub 2017 Sep 4.

PMID:
28882485
15.

In Vitro and In Situ Characterization of Triterpene Glycosides From Cimicifuga racemosa Extract.

Disch L, Forsch K, Siewert B, Drewe J, Fricker G.

J Pharm Sci. 2017 Dec;106(12):3642-3650. doi: 10.1016/j.xphs.2017.07.023. Epub 2017 Aug 4.

PMID:
28827038
16.

Oral delivery of vancomycin by tetraether lipid liposomes.

Uhl P, Pantze S, Storck P, Parmentier J, Witzigmann D, Hofhaus G, Huwyler J, Mier W, Fricker G.

Eur J Pharm Sci. 2017 Oct 15;108:111-118. doi: 10.1016/j.ejps.2017.07.013. Epub 2017 Jul 14.

PMID:
28716758
17.

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human.

Bernard-Gauthier V, Bailey JJ, Mossine AV, Lindner S, Vomacka L, Aliaga A, Shao X, Quesada CA, Sherman P, Mahringer A, Kostikov A, Grand'Maison M, Rosa-Neto P, Soucy JP, Thiel A, Kaplan DR, Fricker G, Wängler B, Bartenstein P, Schirrmacher R, Scott PJH.

J Med Chem. 2017 Aug 24;60(16):6897-6910. doi: 10.1021/acs.jmedchem.7b00396. Epub 2017 Jul 21.

PMID:
28696690
18.

Electrospray Synthesis of Poly(lactide-co-glycolide) Nanoparticles Encapsulating Peptides to Enhance Proliferation of Antigen-Specific CD8+ T Cells.

Furtmann B, Tang J, Kramer S, Eickner T, Luderer F, Fricker G, Gomez A, Heemskerk B, Jähn PS.

J Pharm Sci. 2017 Nov;106(11):3316-3327. doi: 10.1016/j.xphs.2017.06.013. Epub 2017 Jun 23.

PMID:
28652156
19.

Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development.

Bernard-Gauthier V, Mahringer A, Vesnaver M, Fricker G, Schirrmacher R.

Bioorg Med Chem Lett. 2017 Jun 15;27(12):2771-2775. doi: 10.1016/j.bmcl.2017.04.064. Epub 2017 Apr 21.

PMID:
28476569
20.

Development and characterization of novel highly-loaded itraconazole poly(butyl cyanoacrylate) polymeric nanoparticles.

Ćurić A, Möschwitzer JP, Fricker G.

Eur J Pharm Biopharm. 2017 May;114:175-185. doi: 10.1016/j.ejpb.2017.01.014. Epub 2017 Jan 31.

PMID:
28159723
21.

Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine.

Stremmel W, Schmidt KV, Schuhmann V, Kratzer F, Garbade SF, Langhans CD, Fricker G, Okun JG.

PLoS One. 2017 Jan 27;12(1):e0170742. doi: 10.1371/journal.pone.0170742. eCollection 2017.

22.

Archaeal lipids in oral delivery of therapeutic peptides.

Jacobsen AC, Jensen SM, Fricker G, Brandl M, Treusch AH.

Eur J Pharm Sci. 2017 Oct 15;108:101-110. doi: 10.1016/j.ejps.2016.12.036. Epub 2017 Jan 17. Review.

PMID:
28108360
23.

Immediate effects of diamond burr debridement in patients with spontaneous chronic corneal epithelial defects, light and electron microscopic evaluation.

Dawson C, Naranjo C, Sanchez-Maldonado B, Fricker GV, Linn-Pearl RN, Escanilla N, Kafarnik C, Gould DJ, Sanchez RF, Matas-Riera M.

Vet Ophthalmol. 2017 Jan;20(1):11-15. doi: 10.1111/vop.12337. Epub 2015 Dec 21.

PMID:
28044425
24.

The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers - An in vitro and in vivo comparison.

Weinheimer M, Fricker G, Burhenne J, Mylius P, Schubert R.

Eur J Pharm Sci. 2017 Oct 15;108:13-22. doi: 10.1016/j.ejps.2016.08.055. Epub 2016 Aug 30.

PMID:
27590127
25.

Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes.

Tremmel R, Uhl P, Helm F, Wupperfeld D, Sauter M, Mier W, Stremmel W, Hofhaus G, Fricker G.

Int J Pharm. 2016 Oct 15;512(1):87-95. doi: 10.1016/j.ijpharm.2016.08.040. Epub 2016 Aug 20.

PMID:
27553779
26.

Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer's disease treatment.

Loureiro JA, Gomes B, Fricker G, Coelho MAN, Rocha S, Pereira MC.

Colloids Surf B Biointerfaces. 2016 Sep 1;145:8-13. doi: 10.1016/j.colsurfb.2016.04.041. Epub 2016 Apr 20.

PMID:
27131092
27.

A liposomal formulation for the oral application of the investigational hepatitis B drug Myrcludex B.

Uhl P, Helm F, Hofhaus G, Brings S, Kaufman C, Leotta K, Urban S, Haberkorn U, Mier W, Fricker G.

Eur J Pharm Biopharm. 2016 Jun;103:159-166. doi: 10.1016/j.ejpb.2016.03.031. Epub 2016 Apr 2.

PMID:
27049970
28.

ABC transporters at the blood-brain barrier.

Mahringer A, Fricker G.

Expert Opin Drug Metab Toxicol. 2016 May;12(5):499-508. doi: 10.1517/17425255.2016.1168804. Epub 2016 Apr 4. Review.

PMID:
26998936
29.

Predicting spatial variations of tree species richness in tropical forests from high-resolution remote sensing.

Fricker GA, Wolf JA, Saatchi SS, Gillespie TW.

Ecol Appl. 2015 Oct;25(7):1776-89.

PMID:
26591445
30.

Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo Pharmacokinetics.

Litau S, Niedermoser S, Vogler N, Roscher M, Schirrmacher R, Fricker G, Wängler B, Wängler C.

Bioconjug Chem. 2015 Dec 16;26(12):2350-9. doi: 10.1021/acs.bioconjchem.5b00510. Epub 2015 Oct 14.

PMID:
26420336
31.

Survey of the incidence of pectinate ligament dysplasia and glaucoma in the UK Leonberger population.

Fricker GV, Smith K, Gould DJ.

Vet Ophthalmol. 2016 Sep;19(5):379-85. doi: 10.1111/vop.12311. Epub 2015 Sep 11.

PMID:
26359130
32.

Dual ligand immunoliposomes for drug delivery to the brain.

Loureiro JA, Gomes B, Fricker G, Cardoso I, Ribeiro CA, Gaiteiro C, Coelho MA, Pereira Mdo C, Rocha S.

Colloids Surf B Biointerfaces. 2015 Oct 1;134:213-9. doi: 10.1016/j.colsurfb.2015.06.067. Epub 2015 Jul 3.

PMID:
26204501
33.

Development and lyophilization of itraconazole loaded poly(butylcyanoacrylate) nanospheres as a drug delivery system.

Ćurić A, Keller BL, Reul R, Möschwitzer J, Fricker G.

Eur J Pharm Sci. 2015 Oct 12;78:121-31. doi: 10.1016/j.ejps.2015.07.010. Epub 2015 Jul 11.

PMID:
26171880
34.

Comparative Assessment of Complex Stabilities of Radiocopper Chelating Agents by a Combination of Complex Challenge and in vivo Experiments.

Litau S, Seibold U, Vall-Sagarra A, Fricker G, Wängler B, Wängler C.

ChemMedChem. 2015 Jul;10(7):1200-8. doi: 10.1002/cmdc.201500132. Epub 2015 May 25.

PMID:
26011290
35.

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier.

Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G.

Pharm Res. 2015 Sep;32(9):2973-82. doi: 10.1007/s11095-015-1679-1. Epub 2015 May 19.

PMID:
25986174
36.

Liposomal conjugates for drug delivery to the central nervous system.

Helm F, Fricker G.

Pharmaceutics. 2015 Apr 1;7(2):27-42. doi: 10.3390/pharmaceutics7020027.

37.

Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases.

Gartzke D, Delzer J, Laplanche L, Uchida Y, Hoshi Y, Tachikawa M, Terasaki T, Sydor J, Fricker G.

Pharm Res. 2015 Jun;32(6):2060-71. doi: 10.1007/s11095-014-1599-5. Epub 2014 Dec 19.

PMID:
25522789
38.

Nanotoxicity of poly(n-butylcyano-acrylate) nanoparticles at the blood-brain barrier, in human whole blood and in vivo.

Kolter M, Ott M, Hauer C, Reimold I, Fricker G.

J Control Release. 2015 Jan 10;197:165-79. doi: 10.1016/j.jconrel.2014.11.005. Epub 2014 Nov 10.

PMID:
25445700
39.

Improved oral bioavailability of human growth hormone by a combination of liposomes containing bio-enhancers and tetraether lipids and omeprazole.

Parmentier J, Hofhaus G, Thomas S, Cuesta LC, Gropp F, Schröder R, Hartmann K, Fricker G.

J Pharm Sci. 2014 Dec;103(12):3985-3993. doi: 10.1002/jps.24215. Epub 2014 Oct 20.

PMID:
25332052
40.

Radionuclides in drug development.

Uhl P, Fricker G, Haberkorn U, Mier W.

Drug Discov Today. 2015 Feb;20(2):198-208. doi: 10.1016/j.drudis.2014.09.027. Epub 2014 Oct 7. Review.

PMID:
25304182
41.

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems.

Heshmati N, Cheng X, Dapat E, Sassene P, Eisenbrand G, Fricker G, Müllertz A.

J Pharm Pharmacol. 2014 Nov;66(11):1567-75. doi: 10.1111/jphp.12286. Epub 2014 Jun 24.

PMID:
24961657
42.

Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models.

Jähne EA, Eigenmann DE, Culot M, Cecchelli R, Walter FR, Deli MA, Tremmel R, Fricker G, Smiesko M, Hamburger M, Oufir M.

J Pharm Biomed Anal. 2014 Sep;98:235-46. doi: 10.1016/j.jpba.2014.05.026. Epub 2014 May 27.

PMID:
24949819
43.

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand.

Noysang C, Mahringer A, Zeino M, Saeed M, Luanratana O, Fricker G, Bauer R, Efferth T.

J Ethnopharmacol. 2014 Aug 8;155(1):633-41. doi: 10.1016/j.jep.2014.06.001. Epub 2014 Jun 12.

PMID:
24929106
44.

Current status in the therapy of liver diseases.

Uhl P, Fricker G, Haberkorn U, Mier W.

Int J Mol Sci. 2014 Apr 30;15(5):7500-12. doi: 10.3390/ijms15057500. Review.

45.

Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?

Wängler C, Chowdhury S, Höfner G, Djurova P, Purisima EO, Bartenstein P, Wängler B, Fricker G, Wanner KT, Schirrmacher R.

J Med Chem. 2014 May 22;57(10):4368-81. doi: 10.1021/jm5004123. Epub 2014 May 8.

PMID:
24779610
46.

What is the mechanism behind increased permeation rate of a poorly soluble drug from aqueous dispersions of an amorphous solid dispersion?

Frank KJ, Westedt U, Rosenblatt KM, Hölig P, Rosenberg J, Mägerlein M, Fricker G, Brandl M.

J Pharm Sci. 2014 Jun;103(6):1779-86. doi: 10.1002/jps.23979. Epub 2014 Apr 24.

PMID:
24764046
47.

Establishment of optimized MDCK cell lines for reliable efflux transport studies.

Gartzke D, Fricker G.

J Pharm Sci. 2014 Apr;103(4):1298-304. doi: 10.1002/jps.23901. Epub 2014 Feb 15.

PMID:
24532159
48.

Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1.

Tajima Y, Nakagawa H, Tamura A, Kadioglu O, Satake K, Mitani Y, Murase H, Regasini LO, Bolzani Vda S, Ishikawa T, Fricker G, Efferth T.

Phytomedicine. 2014 Feb 15;21(3):323-32. doi: 10.1016/j.phymed.2013.08.024. Epub 2013 Oct 14.

PMID:
24135452
49.

Physicochemical characterization and in vitro permeation of an indirubin derivative.

Heshmati N, Wagner B, Cheng X, Scholz T, Kansy M, Eisenbrand G, Fricker G.

Eur J Pharm Sci. 2013 Nov 20;50(3-4):467-75. doi: 10.1016/j.ejps.2013.08.021. Epub 2013 Aug 28.

PMID:
23994641
50.

Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats.

Heshmati N, Cheng X, Eisenbrand G, Fricker G.

J Pharm Sci. 2013 Oct;102(10):3792-9. doi: 10.1002/jps.23696. Epub 2013 Aug 11.

PMID:
23934779

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