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Items: 1 to 50 of 193

1.
2.

Improving and Evaluating eMMA's Communication Skills: A Chatbot for Managing Medication.

Hess GI, Fricker G, Denecke K.

Stud Health Technol Inform. 2019;259:101-104.

PMID:
30923283
3.

Does eHealth Literacy Impact Patients' Opinion on the EHR?

Möri N, Bürki J, de Oliveira Matos P, Düllmann P, Fricker G, Gehri Y, Glauser R, Gund Y, Haller C, Kilchherr S, Landolt A, Leuenberger L, Lüscher L, Müller N, Schwarz M, Sinnappah T, Uthayathas G, Drewlow J.

Stud Health Technol Inform. 2019;259:95-98.

PMID:
30923281
4.

Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules.

Mahringer A, Bernd A, Miller DS, Fricker G.

Biol Chem. 2019 Sep 25;400(10):1335-1345. doi: 10.1515/hsz-2018-0425.

PMID:
30913027
5.

Effect of methadone and acepromazine premedication on tear production in dogs.

Volk HA, West E, Linn-Pearl RN, Fricker GV, Panti A, Gould DJ.

Vet Rec Open. 2018 Dec 5;5(1):e000298. doi: 10.1136/vetreco-2018-000298. eCollection 2018.

6.

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging.

Schirrmacher R, Bailey JJ, Mossine AV, Scott PJH, Kaiser L, Bartenstein P, Lindner S, Kaplan DR, Kostikov A, Fricker G, Mahringer A, Rosa-Neto P, Schirrmacher E, Wängler C, Wängler B, Thiel A, Soucy JP, Bernard-Gauthier V.

Pharmaceuticals (Basel). 2019 Jan 3;12(1). pii: E7. doi: 10.3390/ph12010007. Review.

7.

Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo.

Zaremba A, Helm F, Fricker G.

Mol Pharm. 2019 Jan 7;16(1):305-317. doi: 10.1021/acs.molpharmaceut.8b00987. Epub 2018 Nov 29.

PMID:
30422662
8.
9.

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

Vall-Sagarra A, Litau S, Decristoforo C, Wängler B, Schirrmacher R, Fricker G, Wängler C.

Pharmaceuticals (Basel). 2018 Jul 4;11(3). pii: E65. doi: 10.3390/ph11030065.

10.

Circulating Troponin I Level in Patients with Acute Ischemic Stroke.

VanHouten J, Fricker G, Collins B, Bhatia R, Ellis C, Schrag M.

Curr Neurol Neurosci Rep. 2018 Apr 20;18(6):32. doi: 10.1007/s11910-018-0842-6.

PMID:
29679162
11.

Practice Patterns of Providers for the Management of Staphylococcus aureus Bacteremia in Children: Results of an Emerging Infections Network Survey.

Wood JB, Fricker GP, Beekmann SE, Polgreen P, Buddy Creech C.

J Pediatric Infect Dis Soc. 2018 Aug 17;7(3):e152-e155. doi: 10.1093/jpids/piy022. Erratum in: J Pediatric Infect Dis Soc. 2018 Dec 3;7(4):359-358.

PMID:
29534244
12.

In Vitro and In Situ Absorption and Metabolism of Sesquiterpenes from Petasites hybridus Extracts.

Disch L, Forsch K, Siewert B, Drewe J, Fricker G.

Planta Med. 2018 Jul;84(11):795-805. doi: 10.1055/s-0044-100401. Epub 2018 Jan 16.

PMID:
29341029
13.

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2018 Jan 12;15(1):3. doi: 10.1186/s12987-017-0086-x.

14.

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging.

Bernard-Gauthier V, Mossine AV, Mahringer A, Aliaga A, Bailey JJ, Shao X, Stauff J, Arteaga J, Sherman P, Grand'Maison M, Rochon PL, Wängler B, Wängler C, Bartenstein P, Kostikov A, Kaplan DR, Fricker G, Rosa-Neto P, Scott PJH, Schirrmacher R.

J Med Chem. 2018 Feb 22;61(4):1737-1743. doi: 10.1021/acs.jmedchem.7b01607. Epub 2018 Jan 5.

PMID:
29257860
15.

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors.

Prause M, Niedermoser S, Wängler C, Decristoforo C, Seibold U, Riester S, Taguchi T, Schirrmacher R, Fricker G, Wängler B.

Nucl Med Biol. 2018 Feb;57:1-11. doi: 10.1016/j.nucmedbio.2017.11.004. Epub 2017 Nov 17.

PMID:
29175467
16.

A Case of a 4-Year-Old Female with a Primary Spinal Malignancy Presenting with Froin's Syndrome.

Hale AT, Fricker GP, Crook TW.

Pediatr Neurosurg. 2018;53(1):64-68. doi: 10.1159/000481514. Epub 2017 Nov 2.

PMID:
29131102
17.

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Greenwood J, Hammarlund-Udenaes M, Jones HC, Stitt AW, Vandenbroucke RE, Romero IA, Campbell M, Fricker G, Brodin B, Manninga H, Gaillard PJ, Schwaninger M, Webster C, Wicher KB, Khrestchatisky M.

Fluids Barriers CNS. 2017 Nov 7;14(1):31. doi: 10.1186/s12987-017-0079-9. Erratum in: Fluids Barriers CNS. 2018 Jan 12;15(1):3.

18.

Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus).

Zaremba A, Miller DS, Fricker G.

Toxicol Appl Pharmacol. 2017 Nov 1;334:88-99. doi: 10.1016/j.taap.2017.09.001. Epub 2017 Sep 4.

PMID:
28882485
19.

In Vitro and In Situ Characterization of Triterpene Glycosides From Cimicifuga racemosa Extract.

Disch L, Forsch K, Siewert B, Drewe J, Fricker G.

J Pharm Sci. 2017 Dec;106(12):3642-3650. doi: 10.1016/j.xphs.2017.07.023. Epub 2017 Aug 4.

PMID:
28827038
20.

Oral delivery of vancomycin by tetraether lipid liposomes.

Uhl P, Pantze S, Storck P, Parmentier J, Witzigmann D, Hofhaus G, Huwyler J, Mier W, Fricker G.

Eur J Pharm Sci. 2017 Oct 15;108:111-118. doi: 10.1016/j.ejps.2017.07.013. Epub 2017 Jul 14.

PMID:
28716758
21.

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human.

Bernard-Gauthier V, Bailey JJ, Mossine AV, Lindner S, Vomacka L, Aliaga A, Shao X, Quesada CA, Sherman P, Mahringer A, Kostikov A, Grand'Maison M, Rosa-Neto P, Soucy JP, Thiel A, Kaplan DR, Fricker G, Wängler B, Bartenstein P, Schirrmacher R, Scott PJH.

J Med Chem. 2017 Aug 24;60(16):6897-6910. doi: 10.1021/acs.jmedchem.7b00396. Epub 2017 Jul 21.

PMID:
28696690
22.

Electrospray Synthesis of Poly(lactide-co-glycolide) Nanoparticles Encapsulating Peptides to Enhance Proliferation of Antigen-Specific CD8+ T Cells.

Furtmann B, Tang J, Kramer S, Eickner T, Luderer F, Fricker G, Gomez A, Heemskerk B, Jähn PS.

J Pharm Sci. 2017 Nov;106(11):3316-3327. doi: 10.1016/j.xphs.2017.06.013. Epub 2017 Jun 23.

PMID:
28652156
23.

Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development.

Bernard-Gauthier V, Mahringer A, Vesnaver M, Fricker G, Schirrmacher R.

Bioorg Med Chem Lett. 2017 Jun 15;27(12):2771-2775. doi: 10.1016/j.bmcl.2017.04.064. Epub 2017 Apr 21.

PMID:
28476569
24.

Development and characterization of novel highly-loaded itraconazole poly(butyl cyanoacrylate) polymeric nanoparticles.

Ćurić A, Möschwitzer JP, Fricker G.

Eur J Pharm Biopharm. 2017 May;114:175-185. doi: 10.1016/j.ejpb.2017.01.014. Epub 2017 Jan 31.

PMID:
28159723
25.

Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine.

Stremmel W, Schmidt KV, Schuhmann V, Kratzer F, Garbade SF, Langhans CD, Fricker G, Okun JG.

PLoS One. 2017 Jan 27;12(1):e0170742. doi: 10.1371/journal.pone.0170742. eCollection 2017.

26.

Archaeal lipids in oral delivery of therapeutic peptides.

Jacobsen AC, Jensen SM, Fricker G, Brandl M, Treusch AH.

Eur J Pharm Sci. 2017 Oct 15;108:101-110. doi: 10.1016/j.ejps.2016.12.036. Epub 2017 Jan 17. Review.

PMID:
28108360
27.

Immediate effects of diamond burr debridement in patients with spontaneous chronic corneal epithelial defects, light and electron microscopic evaluation.

Dawson C, Naranjo C, Sanchez-Maldonado B, Fricker GV, Linn-Pearl RN, Escanilla N, Kafarnik C, Gould DJ, Sanchez RF, Matas-Riera M.

Vet Ophthalmol. 2017 Jan;20(1):11-15. doi: 10.1111/vop.12337. Epub 2015 Dec 21.

PMID:
28044425
28.

The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers - An in vitro and in vivo comparison.

Weinheimer M, Fricker G, Burhenne J, Mylius P, Schubert R.

Eur J Pharm Sci. 2017 Oct 15;108:13-22. doi: 10.1016/j.ejps.2016.08.055. Epub 2016 Aug 30.

PMID:
27590127
29.

Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes.

Tremmel R, Uhl P, Helm F, Wupperfeld D, Sauter M, Mier W, Stremmel W, Hofhaus G, Fricker G.

Int J Pharm. 2016 Oct 15;512(1):87-95. doi: 10.1016/j.ijpharm.2016.08.040. Epub 2016 Aug 20.

PMID:
27553779
30.

Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer's disease treatment.

Loureiro JA, Gomes B, Fricker G, Coelho MAN, Rocha S, Pereira MC.

Colloids Surf B Biointerfaces. 2016 Sep 1;145:8-13. doi: 10.1016/j.colsurfb.2016.04.041. Epub 2016 Apr 20.

PMID:
27131092
31.

A liposomal formulation for the oral application of the investigational hepatitis B drug Myrcludex B.

Uhl P, Helm F, Hofhaus G, Brings S, Kaufman C, Leotta K, Urban S, Haberkorn U, Mier W, Fricker G.

Eur J Pharm Biopharm. 2016 Jun;103:159-166. doi: 10.1016/j.ejpb.2016.03.031. Epub 2016 Apr 2.

PMID:
27049970
32.

ABC transporters at the blood-brain barrier.

Mahringer A, Fricker G.

Expert Opin Drug Metab Toxicol. 2016 May;12(5):499-508. doi: 10.1517/17425255.2016.1168804. Epub 2016 Apr 4. Review.

PMID:
26998936
33.

Predicting spatial variations of tree species richness in tropical forests from high-resolution remote sensing.

Fricker GA, Wolf JA, Saatchi SS, Gillespie TW.

Ecol Appl. 2015 Oct;25(7):1776-89.

PMID:
26591445
34.

Next Generation of SiFAlin-Based TATE Derivatives for PET Imaging of SSTR-Positive Tumors: Influence of Molecular Design on In Vitro SSTR Binding and In Vivo Pharmacokinetics.

Litau S, Niedermoser S, Vogler N, Roscher M, Schirrmacher R, Fricker G, Wängler B, Wängler C.

Bioconjug Chem. 2015 Dec 16;26(12):2350-9. doi: 10.1021/acs.bioconjchem.5b00510. Epub 2015 Oct 14.

PMID:
26420336
35.

Survey of the incidence of pectinate ligament dysplasia and glaucoma in the UK Leonberger population.

Fricker GV, Smith K, Gould DJ.

Vet Ophthalmol. 2016 Sep;19(5):379-85. doi: 10.1111/vop.12311. Epub 2015 Sep 11.

PMID:
26359130
36.

Dual ligand immunoliposomes for drug delivery to the brain.

Loureiro JA, Gomes B, Fricker G, Cardoso I, Ribeiro CA, Gaiteiro C, Coelho MA, Pereira Mdo C, Rocha S.

Colloids Surf B Biointerfaces. 2015 Oct 1;134:213-9. doi: 10.1016/j.colsurfb.2015.06.067. Epub 2015 Jul 3.

PMID:
26204501
37.

Development and lyophilization of itraconazole loaded poly(butylcyanoacrylate) nanospheres as a drug delivery system.

Ćurić A, Keller BL, Reul R, Möschwitzer J, Fricker G.

Eur J Pharm Sci. 2015 Oct 12;78:121-31. doi: 10.1016/j.ejps.2015.07.010. Epub 2015 Jul 11.

PMID:
26171880
38.

Comparative Assessment of Complex Stabilities of Radiocopper Chelating Agents by a Combination of Complex Challenge and in vivo Experiments.

Litau S, Seibold U, Vall-Sagarra A, Fricker G, Wängler B, Wängler C.

ChemMedChem. 2015 Jul;10(7):1200-8. doi: 10.1002/cmdc.201500132. Epub 2015 May 25.

PMID:
26011290
39.

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier.

Bernd A, Ott M, Ishikawa H, Schroten H, Schwerk C, Fricker G.

Pharm Res. 2015 Sep;32(9):2973-82. doi: 10.1007/s11095-015-1679-1. Epub 2015 May 19.

PMID:
25986174
40.

Liposomal conjugates for drug delivery to the central nervous system.

Helm F, Fricker G.

Pharmaceutics. 2015 Apr 1;7(2):27-42. doi: 10.3390/pharmaceutics7020027.

41.

Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases.

Gartzke D, Delzer J, Laplanche L, Uchida Y, Hoshi Y, Tachikawa M, Terasaki T, Sydor J, Fricker G.

Pharm Res. 2015 Jun;32(6):2060-71. doi: 10.1007/s11095-014-1599-5. Epub 2014 Dec 19.

PMID:
25522789
42.

Nanotoxicity of poly(n-butylcyano-acrylate) nanoparticles at the blood-brain barrier, in human whole blood and in vivo.

Kolter M, Ott M, Hauer C, Reimold I, Fricker G.

J Control Release. 2015 Jan 10;197:165-79. doi: 10.1016/j.jconrel.2014.11.005. Epub 2014 Nov 10.

PMID:
25445700
43.

Improved oral bioavailability of human growth hormone by a combination of liposomes containing bio-enhancers and tetraether lipids and omeprazole.

Parmentier J, Hofhaus G, Thomas S, Cuesta LC, Gropp F, Schröder R, Hartmann K, Fricker G.

J Pharm Sci. 2014 Dec;103(12):3985-3993. doi: 10.1002/jps.24215. Epub 2014 Oct 20.

PMID:
25332052
44.

Radionuclides in drug development.

Uhl P, Fricker G, Haberkorn U, Mier W.

Drug Discov Today. 2015 Feb;20(2):198-208. doi: 10.1016/j.drudis.2014.09.027. Epub 2014 Oct 7. Review.

PMID:
25304182
45.

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems.

Heshmati N, Cheng X, Dapat E, Sassene P, Eisenbrand G, Fricker G, Müllertz A.

J Pharm Pharmacol. 2014 Nov;66(11):1567-75. doi: 10.1111/jphp.12286. Epub 2014 Jun 24.

PMID:
24961657
46.

Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models.

Jähne EA, Eigenmann DE, Culot M, Cecchelli R, Walter FR, Deli MA, Tremmel R, Fricker G, Smiesko M, Hamburger M, Oufir M.

J Pharm Biomed Anal. 2014 Sep;98:235-46. doi: 10.1016/j.jpba.2014.05.026. Epub 2014 May 27.

PMID:
24949819
47.

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand.

Noysang C, Mahringer A, Zeino M, Saeed M, Luanratana O, Fricker G, Bauer R, Efferth T.

J Ethnopharmacol. 2014 Aug 8;155(1):633-41. doi: 10.1016/j.jep.2014.06.001. Epub 2014 Jun 12.

PMID:
24929106
48.

Current status in the therapy of liver diseases.

Uhl P, Fricker G, Haberkorn U, Mier W.

Int J Mol Sci. 2014 Apr 30;15(5):7500-12. doi: 10.3390/ijms15057500. Review.

49.

Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?

Wängler C, Chowdhury S, Höfner G, Djurova P, Purisima EO, Bartenstein P, Wängler B, Fricker G, Wanner KT, Schirrmacher R.

J Med Chem. 2014 May 22;57(10):4368-81. doi: 10.1021/jm5004123. Epub 2014 May 8.

PMID:
24779610
50.

What is the mechanism behind increased permeation rate of a poorly soluble drug from aqueous dispersions of an amorphous solid dispersion?

Frank KJ, Westedt U, Rosenblatt KM, Hölig P, Rosenberg J, Mägerlein M, Fricker G, Brandl M.

J Pharm Sci. 2014 Jun;103(6):1779-86. doi: 10.1002/jps.23979. Epub 2014 Apr 24.

PMID:
24764046

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