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Flagellin hypervariable region determines symbiotic properties of commensal Escherichia coli strains.

Steimle A, Menz S, Bender A, Ball B, Weber ANR, Hagemann T, Lange A, Maerz JK, Parusel R, Michaelis L, Schäfer A, Yao H, Löw HC, Beier S, Tesfazgi Mebrhatu M, Gronbach K, Wagner S, Voehringer D, Schaller M, Fehrenbacher B, Autenrieth IB, Oelschlaeger TA, Frick JS.

PLoS Biol. 2019 Jun 17;17(6):e3000334. doi: 10.1371/journal.pbio.3000334. eCollection 2019 Jun.


The roles of the chaperone-like protein CpeZ and the phycoerythrobilin lyase CpeY in phycoerythrin biogenesis.

Kronfel CM, Biswas A, Frick JP, Gutu A, Blensdorf T, Karty JA, Kehoe DM, Schluchter WM.

Biochim Biophys Acta Bioenerg. 2019 Jul 1;1860(7):549-561. doi: 10.1016/j.bbabio.2019.06.001. Epub 2019 Jun 4.


Suitability of the German version of the Manchester Triage System to redirect emergency department patients to general practitioner care: a prospective cohort study.

Slagman A, Greiner F, Searle J, Harriss L, Thompson F, Frick J, Bolanaki M, Lindner T, Möckel M.

BMJ Open. 2019 May 6;9(5):e024896. doi: 10.1136/bmjopen-2018-024896.


A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses.

Lange A, Schäfer A, Frick JS.

J Vis Exp. 2019 Mar 21;(145). doi: 10.3791/59270.


CpeF is the bilin lyase that ligates the doubly linked phycoerythrobilin on β-phycoerythrin in the cyanobacterium Fremyella diplosiphon.

Kronfel CM, Hernandez CV, Frick JP, Hernandez LS, Gutu A, Karty JA, Boutaghou MN, Kehoe DM, Cole RB, Schluchter WM.

J Biol Chem. 2019 Mar 15;294(11):3987-3999. doi: 10.1074/jbc.RA118.007221. Epub 2019 Jan 22.


The h-Sbx WO3+2x Oxygen Excess Antimony Tungsten Bronze.

von Rohr FO, Ryser A, Ji H, Stolze K, Tao J, Frick JJ, Patzke GR, Cava RJ.

Chemistry. 2019 Feb 6;25(8):2082-2088. doi: 10.1002/chem.201805251. Epub 2019 Jan 9.


Single-Crystal Growth and Characterization of the Chalcopyrite Semiconductor CuInTe2 for Photoelectrochemical Solar Fuel Production.

Frick JJ, Topp A, Klemenz S, Krivenkov M, Varykhalov A, Ast CR, Bocarsly AB, Schoop LM.

J Phys Chem Lett. 2018 Dec 6;9(23):6833-6840. doi: 10.1021/acs.jpclett.8b03100. Epub 2018 Nov 20.


Galleria mellonella: A Novel Invertebrate Model to Distinguish Intestinal Symbionts From Pathobionts.

Lange A, Schäfer A, Bender A, Steimle A, Beier S, Parusel R, Frick JS.

Front Immunol. 2018 Sep 19;9:2114. doi: 10.3389/fimmu.2018.02114. eCollection 2018.


[Quality of German-Language Guidelines for Post-Stroke Rehabilitation of Aphasia and Dysarthria - Results of a Systematic Review and of an International Comparison].

Mandl L, Schindel D, Deutschbein J, Frick J, Schenk L.

Rehabilitation (Stuttg). 2018 Oct 1. doi: 10.1055/a-0651-9838. [Epub ahead of print] German.


Using clinical and genetic data to predict pulmonary hypertension in bronchopulmonary dysplasia.

Trittmann JK, Bartenschlag A, Zmuda EJ, Frick J, Stewart WCL, Nelin LD.

Acta Paediatr. 2018 Dec;107(12):2158-2164. doi: 10.1111/apa.14600.


Chemotherapy re-challenge response rate in metastatic colorectal cancer.

Chambers AE, Frick J, Tanner N, Gerkin R, Kundranda M, Dragovich T.

J Gastrointest Oncol. 2018 Aug;9(4):679-686. doi: 10.21037/jgo.2018.04.08.


Fungi as Part of the Microbiota and Interactions with Intestinal Bacteria.

Kapitan M, Niemiec MJ, Steimle A, Frick JS, Jacobsen ID.

Curr Top Microbiol Immunol. 2018 Jul 31. doi: 10.1007/82_2018_117. [Epub ahead of print]


The Macular Carotenoids are Associated with Cognitive Function in Preadolescent Children.

Saint SE, Renzi-Hammond LM, Khan NA, Hillman CH, Frick JE, Hammond BR.

Nutrients. 2018 Feb 10;10(2). pii: E193. doi: 10.3390/nu10020193.


Genome Sequence of Galleria mellonella (Greater Wax Moth).

Lange A, Beier S, Huson DH, Parusel R, Iglauer F, Frick JS.

Genome Announc. 2018 Jan 11;6(2). pii: e01220-17. doi: 10.1128/genomeA.01220-17.


The performance of tranchet blows at the Late Middle Paleolithic site of Grotte de la Verpillière I (Saône-et-Loire, France).

Frick JA, Herkert K, Hoyer CT, Floss H.

PLoS One. 2017 Nov 30;12(11):e0188990. doi: 10.1371/journal.pone.0188990. eCollection 2017.


Proteome and phosphoproteome analysis of commensally induced dendritic cell maturation states.

Korkmaz AG, Popov T, Peisl L, Codrea MC, Nahnsen S, Steimle A, Velic A, Macek B, von Bergen M, Bernhardt J, Frick JS.

J Proteomics. 2018 May 30;180:11-24. doi: 10.1016/j.jprot.2017.11.008. Epub 2017 Nov 15.


Correction to: Fragebogen zur Inanspruchnahme der Notaufnahmen : Implikationen für die Patientenbefragung.

Frick J, Möckel M, Schmiedhofer M, Searle J, Erdmann B, Erhart M, Slagman A.

Med Klin Intensivmed Notfmed. 2019 Feb;114(1):45. doi: 10.1007/s00063-017-0363-0. German. No abstract available.


Suitability of current definitions of ambulatory care sensitive conditions for research in emergency department patients: a secondary health data analysis.

Frick J, Möckel M, Muller R, Searle J, Somasundaram R, Slagman A.

BMJ Open. 2017 Oct 22;7(10):e016109. doi: 10.1136/bmjopen-2017-016109.


[Questionnaire for the utilization of the Emergency Department : Implications for the patient survey].

Frick J, Möckel M, Schmiedhofer M, Searle J, Erdmann B, Erhart M, Slagman A.

Med Klin Intensivmed Notfmed. 2019 Feb;114(1):38-44. doi: 10.1007/s00063-017-0345-2. Epub 2017 Sep 12. German. Erratum in: Med Klin Intensivmed Notfmed. 2019 Feb;114(1):45.


An important question: Which LPS do you use?

Parusel R, Steimle A, Lange A, Schäfer A, Maerz JK, Bender A, Frick JS.

Virulence. 2017 Nov 17;8(8):1890-1893. doi: 10.1080/21505594.2017.1361100. Epub 2017 Sep 12. No abstract available.


Effects of Cluster Sets and Rest-Redistribution on Mechanical Responses to Back Squats in Trained Men.

Tufano JJ, Conlon JA, Nimphius S, Brown LE, Petkovic A, Frick J, Haff GG.

J Hum Kinet. 2017 Aug 1;58:35-43. doi: 10.1515/hukin-2017-0069. eCollection 2017 Sep.


Developmental trends in infant temporal processing speed.

Saint SE, Hammond BR Jr, O'Brien KJ, Frick JE.

Vision Res. 2017 Sep;138:71-77. doi: 10.1016/j.visres.2017.07.004. Epub 2017 Aug 4.


Outer membrane vesicles blebbing contributes to B. vulgatus mpk-mediated immune response silencing.

Maerz JK, Steimle A, Lange A, Bender A, Fehrenbacher B, Frick JS.

Gut Microbes. 2018 Jan 2;9(1):1-12. doi: 10.1080/19490976.2017.1344810. Epub 2017 Jul 13.


Analytical and Clinical Validation of a Point-of-Care Cardiac Troponin T Test with an Improved Detection Limit.

Jungbauer C, Hupf J, Giannitsis E, Frick J, Slagman A, Ehret C, Herbert N, Jung C, Zerback R, Bertsch T, Christ M.

Clin Lab. 2017 Apr 1;63(4):633-645. doi: 10.7754/Clin.Lab.2016.160814.


Phosphotransferase systems in Enterococcus faecalis OG1RF enhance anti-stress capacity in vitro and in vivo.

Peng Z, Ehrmann MA, Waldhuber A, Niemeyer C, Miethke T, Frick JS, Xiong T, Vogel RF.

Res Microbiol. 2017 Jul - Aug;168(6):558-566. doi: 10.1016/j.resmic.2017.03.003. Epub 2017 Mar 29.


[Perception of the Emergency Department for Outpatient Care in a Rural Region in Saxony-Anhalt: A Qualitative Survey of Patients and General Practitioners].

Schmiedhofer M, Searle J, Slagman A, Frick J, Ruhla S, Möckel M.

Dtsch Med Wochenschr. 2017 May;142(10):e61-e73. doi: 10.1055/s-0043-100639. Epub 2017 Mar 29. German.


Successful treatment of pouchitis with Vedolizumab, but not fecal microbiota transfer (FMT), after proctocolectomy in ulcerative colitis.

Schmid M, Frick JS, Malek N, Goetz M.

Int J Colorectal Dis. 2017 Apr;32(4):597-598. doi: 10.1007/s00384-017-2761-4. Epub 2017 Jan 17. No abstract available.


Microbiome and chronic inflammatory bowel diseases.

Wehkamp J, Frick JS.

J Mol Med (Berl). 2017 Jan;95(1):21-28. doi: 10.1007/s00109-016-1495-z. Epub 2016 Dec 17. Review.


Patient motives behind low-acuity visits to the emergency department in Germany: a qualitative study comparing urban and rural sites.

Schmiedhofer M, Möckel M, Slagman A, Frick J, Ruhla S, Searle J.

BMJ Open. 2016 Nov 16;6(11):e013323. doi: 10.1136/bmjopen-2016-013323.


Acute heart failure facts and numbers: acute heart failure populations.

Searle J, Frick J, Möckel M.

ESC Heart Fail. 2016 Jun;3(2):65-70. Epub 2016 Apr 25.


Non-invasive detection and successful treatment of a Helicobacter pylori infection in a captive rhesus macaque.

Semrau A, Gerold S, Frick JS, Iglauer F.

Lab Anim. 2017 Apr;51(2):208-211. doi: 10.1177/0023677216669179. Epub 2016 Sep 24.


Symbiotic gut commensal bacteria act as host cathepsin S activity regulators.

Steimle A, Gronbach K, Beifuss B, Schäfer A, Harmening R, Bender A, Maerz JK, Lange A, Michaelis L, Maurer A, Menz S, McCoy K, Autenrieth IB, Kalbacher H, Frick JS.

J Autoimmun. 2016 Dec;75:82-95. doi: 10.1016/j.jaut.2016.07.009. Epub 2016 Jul 30.


Extensive Mobilome-Driven Genome Diversification in Mouse Gut-Associated Bacteroides vulgatus mpk.

Lange A, Beier S, Steimle A, Autenrieth IB, Huson DH, Frick JS.

Genome Biol Evol. 2016 Apr 25;8(4):1197-207. doi: 10.1093/gbe/evw070.


Structure and function: Lipid A modifications in commensals and pathogens.

Steimle A, Autenrieth IB, Frick JS.

Int J Med Microbiol. 2016 Aug;306(5):290-301. doi: 10.1016/j.ijmm.2016.03.001. Epub 2016 Mar 5. Review.


Molecular Mechanisms of Induction of Tolerant and Tolerogenic Intestinal Dendritic Cells in Mice.

Steimle A, Frick JS.

J Immunol Res. 2016;2016:1958650. doi: 10.1155/2016/1958650. Epub 2016 Feb 11. Review.


Intestinal microbiota: From sequencing to function.

Frick JS, Haller D.

Int J Med Microbiol. 2016 Aug;306(5):255-256. doi: 10.1016/j.ijmm.2016.02.007. Epub 2016 Feb 21. No abstract available.


A novel approach for reliable detection of cathepsin S activities in mouse antigen presenting cells.

Steimle A, Kalbacher H, Maurer A, Beifuss B, Bender A, Schäfer A, Müller R, Autenrieth IB, Frick JS.

J Immunol Methods. 2016 May;432:87-94. doi: 10.1016/j.jim.2016.02.015. Epub 2016 Feb 18.


A single nucleotide polymorphism in the dimethylarginine dimethylaminohydrolase gene is associated with lower risk of pulmonary hypertension in bronchopulmonary dysplasia.

Trittmann JK, Gastier-Foster JM, Zmuda EJ, Frick J, Rogers LK, Vieland VJ, Chicoine LG, Nelin LD.

Acta Paediatr. 2016 Apr;105(4):e170-5. doi: 10.1111/apa.13296. Epub 2016 Jan 11.


Platelet-derived HMGB1 is a critical mediator of thrombosis.

Vogel S, Bodenstein R, Chen Q, Feil S, Feil R, Rheinlaender J, Schäffer TE, Bohn E, Frick JS, Borst O, Münzer P, Walker B, Markel J, Csanyi G, Pagano PJ, Loughran P, Jessup ME, Watkins SC, Bullock GC, Sperry JL, Zuckerbraun BS, Billiar TR, Lotze MT, Gawaz M, Neal MD.

J Clin Invest. 2015 Dec;125(12):4638-54. doi: 10.1172/JCI81660. Epub 2015 Nov 9.


Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Stammler D, Eigenbrod T, Menz S, Frick JS, Sweet MJ, Shakespear MR, Jantsch J, Siegert I, Wölfle S, Langer JD, Oehme I, Schaefer L, Fischer A, Knievel J, Heeg K, Dalpke AH, Bode KA.

J Immunol. 2015 Dec 1;195(11):5421-31. doi: 10.4049/jimmunol.1501195. Epub 2015 Oct 30.


Outbreak of Tuberculosis in a Colony of Rhesus Monkeys (Macaca mulatta) after Possible Indirect Contact with a Human TB Patient.

Mätz-Rensing K, Hartmann T, Wendel GM, Frick JS, Homolka S, Richter E, Munk MH, Kaup FJ.

J Comp Pathol. 2015 Aug-Oct;153(2-3):81-91. doi: 10.1016/j.jcpa.2015.05.006. Epub 2015 Jul 10.


The effect of an apolipoprotein A-I-containing high-density lipoprotein-mimetic particle (CER-001) on carotid artery wall thickness in patients with homozygous familial hypercholesterolemia: The Modifying Orphan Disease Evaluation (MODE) study.

Hovingh GK, Smits LP, Stefanutti C, Soran H, Kwok S, de Graaf J, Gaudet D, Keyserling CH, Klepp H, Frick J, Paolini JF, Dasseux JL, Kastelein JJ, Stroes ES.

Am Heart J. 2015 May;169(5):736-742.e1. doi: 10.1016/j.ahj.2015.01.008. Epub 2015 Jan 28.


MGMT inhibition suppresses survivin expression in pancreatic cancer.

Bobustuc GC, Patel A, Thompson M, Srivenugopal KS, Frick J, Weese J, Konduri SD.

Pancreas. 2015 May;44(4):626-35. doi: 10.1097/MPA.0000000000000299.


Synthetic Lethal Screens Identify Vulnerabilities in GPCR Signaling and Cytoskeletal Organization in E-Cadherin-Deficient Cells.

Telford BJ, Chen A, Beetham H, Frick J, Brew TP, Gould CM, Single A, Godwin T, Simpson KJ, Guilford P.

Mol Cancer Ther. 2015 May;14(5):1213-23. doi: 10.1158/1535-7163.MCT-14-1092. Epub 2015 Mar 16.


Incidence, prevalence and 1-year all-cause mortality of heart failure in Germany: a study based on electronic healthcare data of more than six million persons.

Ohlmeier C, Mikolajczyk R, Frick J, Prütz F, Haverkamp W, Garbe E.

Clin Res Cardiol. 2015 Aug;104(8):688-96. doi: 10.1007/s00392-015-0841-4. Epub 2015 Mar 17.


TLR signaling-induced CD103-expressing cells protect against intestinal inflammation.

Wittmann A, Bron PA, van Swam II, Kleerebezem M, Adam P, Gronbach K, Menz S, Flade I, Bender A, Schäfer A, Korkmaz AG, Parusel R, Autenrieth IB, Frick JS.

Inflamm Bowel Dis. 2015 Mar;21(3):507-19. doi: 10.1097/MIB.0000000000000292.


Regulatory T-cell impairment in cystic fibrosis patients with chronic pseudomonas infection.

Hector A, Schäfer H, Pöschel S, Fischer A, Fritzsching B, Ralhan A, Carevic M, Öz H, Zundel S, Hogardt M, Bakele M, Rieber N, Riethmueller J, Graepler-Mainka U, Stahl M, Bender A, Frick JS, Mall M, Hartl D.

Am J Respir Crit Care Med. 2015 Apr 15;191(8):914-23. doi: 10.1164/rccm.201407-1381OC.


Controlling pharmaceutical crystallization with designed polymeric heteronuclei.

Pfund LY, Price CP, Frick JJ, Matzger AJ.

J Am Chem Soc. 2015 Jan 21;137(2):871-5. doi: 10.1021/ja511106j. Epub 2015 Jan 6.


NOD2 stimulation by Staphylococcus aureus-derived peptidoglycan is boosted by Toll-like receptor 2 costimulation with lipoproteins in dendritic cells.

Schäffler H, Demircioglu DD, Kühner D, Menz S, Bender A, Autenrieth IB, Bodammer P, Lamprecht G, Götz F, Frick JS.

Infect Immun. 2014 Nov;82(11):4681-8. doi: 10.1128/IAI.02043-14. Epub 2014 Aug 25.


Arginase I gene single-nucleotide polymorphism is associated with decreased risk of pulmonary hypertension in bronchopulmonary dysplasia.

Trittmann JK, Nelin LD, Zmuda EJ, Gastier-Foster JM, Chen B, Backes CH, Frick J, Vaynshtok P, Vieland VJ, Klebanoff MA.

Acta Paediatr. 2014 Oct;103(10):e439-43. doi: 10.1111/apa.12717. Epub 2014 Jul 6.

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