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Items: 28

1.

Mapping the functional anatomy of Orai1 transmembrane domains for CRAC channel gating.

Yeung PS, Yamashita M, Ing CE, Pom├Ęs R, Freymann DM, Prakriya M.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5193-E5202. doi: 10.1073/pnas.1718373115. Epub 2018 May 14.

2.

Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.

Klosowiak JL, Park S, Smith KP, French ME, Focia PJ, Freymann DM, Rice SE.

Sci Rep. 2016 Sep 8;6:33019. doi: 10.1038/srep33019.

3.

Structural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein Miro.

Klosowiak JL, Focia PJ, Chakravarthy S, Landahl EC, Freymann DM, Rice SE.

EMBO Rep. 2013 Nov;14(11):968-74. doi: 10.1038/embor.2013.151. Epub 2013 Sep 27.

4.

Structure of a tetrameric galectin from Cinachyrella sp. (ball sponge).

Freymann DM, Nakamura Y, Focia PJ, Sakai R, Swanson GT.

Acta Crystallogr D Biol Crystallogr. 2012 Sep;68(Pt 9):1163-74. doi: 10.1107/S0907444912022834. Epub 2012 Aug 18.

5.

Nucleotide-binding flexibility in ultrahigh-resolution structures of the SRP GTPase Ffh.

Ramirez UD, Focia PJ, Freymann DM.

Acta Crystallogr D Biol Crystallogr. 2008 Oct;64(Pt 10):1043-53. doi: 10.1107/S090744490802444X. Epub 2008 Sep 19.

6.

X-ray structure of the T. aquaticus FtsY:GDP complex suggests functional roles for the C-terminal helix of the SRP GTPases.

Gawronski-Salerno J, Coon JS 5th, Focia PJ, Freymann DM.

Proteins. 2007 Mar 1;66(4):984-95.

7.

Structure of the GMPPNP-stabilized NG domain complex of the SRP GTPases Ffh and FtsY.

Gawronski-Salerno J, Freymann DM.

J Struct Biol. 2007 Apr;158(1):122-8. Epub 2006 Nov 3.

8.

Analysis of protein hydration in ultrahigh-resolution structures of the SRP GTPase Ffh.

Ramirez UD, Freymann DM.

Acta Crystallogr D Biol Crystallogr. 2006 Dec;62(Pt 12):1520-34. Epub 2006 Nov 23.

9.

Structure of a GDP:AlF4 complex of the SRP GTPases Ffh and FtsY, and identification of a peripheral nucleotide interaction site.

Focia PJ, Gawronski-Salerno J, Coon JS 5th, Freymann DM.

J Mol Biol. 2006 Jul 14;360(3):631-43. Epub 2006 May 26.

10.

Purification of RanGDP, RanGTP, and RanGMPPNP by ion exchange chromatography.

Bibak N, Paul RM, Freymann DM, Yaseen NR.

Anal Biochem. 2004 Oct 1;333(1):57-64.

PMID:
15351280
11.

Heterodimeric GTPase core of the SRP targeting complex.

Focia PJ, Shepotinovskaya IV, Seidler JA, Freymann DM.

Science. 2004 Jan 16;303(5656):373-7.

12.

Novel protein and Mg2+ configurations in the Mg2+GDP complex of the SRP GTPase ffh.

Focia PJ, Alam H, Lu T, Ramirez UD, Freymann DM.

Proteins. 2004 Feb 1;54(2):222-30.

13.

Crystallization of the GMPPCP complex of the NG domains of Thermus aquaticus Ffh and FtsY.

Shepotinovskaya IV, Focia PJ, Freymann DM.

Acta Crystallogr D Biol Crystallogr. 2003 Oct;59(Pt 10):1834-7. Epub 2003 Sep 19.

14.

Structural basis for mobility in the 1.1 A crystal structure of the NG domain of Thermus aquaticus Ffh.

Ramirez UD, Minasov G, Focia PJ, Stroud RM, Walter P, Kuhn P, Freymann DM.

J Mol Biol. 2002 Jul 19;320(4):783-99.

15.
16.

Conserved tryptophan in the core domain of transglutaminase is essential for catalytic activity.

Murthy SN, Iismaa S, Begg G, Freymann DM, Graham RM, Lorand L.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2738-42. Epub 2002 Feb 26.

17.
18.

The signal recognition particle.

Keenan RJ, Freymann DM, Stroud RM, Walter P.

Annu Rev Biochem. 2001;70:755-75. Review.

PMID:
11395422
19.

Efficient identification of inhibitors targeting the closed active site conformation of the HPRT from Trypanosoma cruzi.

Freymann DM, Wenck MA, Engel JC, Feng J, Focia PJ, Eakin AE, Craig SP.

Chem Biol. 2000 Dec;7(12):957-68.

20.

Role of 4.5S RNA in assembly of the bacterial signal recognition particle with its receptor.

Peluso P, Herschlag D, Nock S, Freymann DM, Johnson AE, Walter P.

Science. 2000 Jun 2;288(5471):1640-3.

21.

The crystal structure of thymidylate synthase from Pneumocystis carinii reveals a fungal insert important for drug design.

Anderson AC, Perry KM, Freymann DM, Stroud RM.

J Mol Biol. 2000 Mar 31;297(3):645-57.

PMID:
10731418
22.

Structure of the phylogenetically most conserved domain of SRP RNA.

Schmitz U, Behrens S, Freymann DM, Keenan RJ, Lukavsky P, Walter P, James TL.

RNA. 1999 Nov;5(11):1419-29.

23.

Functional changes in the structure of the SRP GTPase on binding GDP and Mg2+GDP.

Freymann DM, Keenan RJ, Stroud RM, Walter P.

Nat Struct Biol. 1999 Aug;6(8):793-801.

PMID:
10426959
24.

Crystal structure of the signal sequence binding subunit of the signal recognition particle.

Keenan RJ, Freymann DM, Walter P, Stroud RM.

Cell. 1998 Jul 24;94(2):181-91.

25.

Structure of the conserved GTPase domain of the signal recognition particle.

Freymann DM, Keenan RJ, Stroud RM, Walter P.

Nature. 1997 Jan 23;385(6614):361-4.

PMID:
9002524
26.

NMR studies of the most conserved RNA domain of the mammalian signal recognition particle (SRP).

Schmitz U, Freymann DM, James TL, Keenan RJ, Vinayak R, Walter P.

RNA. 1996 Dec;2(12):1213-27.

27.

Functional substitution of the signal recognition particle 54-kDa subunit by its Escherichia coli homolog.

Bernstein HD, Zopf D, Freymann DM, Walter P.

Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5229-33.

28.

6 A-resolution X-ray structure of a variable surface glycoprotein from Trypanosoma brucei.

Freymann DM, Metcalf P, Turner M, Wiley DC.

Nature. 1984 Sep 13-19;311(5982):167-9.

PMID:
6472475

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