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The Axon Initial Segment is the Dominant Contributor to the Neuron's Extracellular Electrical Potential Landscape.

Bakkum DJ, Obien MEJ, Radivojevic M, Jäckel D, Frey U, Takahashi H, Hierlemann A.

Adv Biosyst. 2019 Feb;3(2). pii: 1800308. doi: 10.1002/adbi.201800308. Epub 2018 Nov 29.


Exposure to moderate air pollution and associations with lung function at school-age: A birth cohort study.

Usemann J, Decrue F, Korten I, Proietti E, Gorlanova O, Vienneau D, Fuchs O, Latzin P, Röösli M, Frey U; BILD study group.

Environ Int. 2019 Mar 11;126:682-689. doi: 10.1016/j.envint.2018.12.019. [Epub ahead of print]


Can a brief psychological expectancy intervention improve postoperative pain? A randomized, controlled trial in breast cancer patients.

Benson S, Hagen S, Hoffmann O, Pasler A, Bingel U, Schedlowski M, Peters J, Elsenbruch S, Frey UH.

Pain. 2019 Mar 4. doi: 10.1097/j.pain.0000000000001546. [Epub ahead of print]


Addressing the complexity of prenatal and postnatal environmental exposures affecting childhood lung function.

Frey U, Usemann J.

Lancet Planet Health. 2019 Feb;3(2):e51-e52. doi: 10.1016/S2542-5196(19)30011-7. Epub 2019 Feb 6. No abstract available.


Association of long-term exposure to traffic-related PM10 with heart rate variability and heart rate dynamics in healthy subjects.

Meier-Girard D, Delgado-Eckert E, Schaffner E, Schindler C, Künzli N, Adam M, Pichot V, Kronenberg F, Imboden M, Frey U, Probst-Hensch N.

Environ Int. 2019 Apr;125:107-116. doi: 10.1016/j.envint.2019.01.031. Epub 2019 Feb 1.


Accurate signal-source localization in brain slices by means of high-density microelectrode arrays.

Obien MEJ, Hierlemann A, Frey U.

Sci Rep. 2019 Jan 28;9(1):788. doi: 10.1038/s41598-018-36895-y.


Distinguishing protest responses in contingent valuation: A conceptualization of motivations and attitudes behind them.

Frey UJ, Pirscher F.

PLoS One. 2019 Jan 8;14(1):e0209872. doi: 10.1371/journal.pone.0209872. eCollection 2019.


Remote ischaemic preconditioning increases serum extracellular vesicle concentrations with altered micro-RNA signature in CABG patients.

Frey UH, Klaassen M, Ochsenfarth C, Murke F, Thielmann M, Kottenberg E, Kleinbongard P, Klenke S, Engler A, Heusch G, Giebel B, Peters J.

Acta Anaesthesiol Scand. 2019 Apr;63(4):483-492. doi: 10.1111/aas.13296. Epub 2018 Dec 11.


True Lumen Stabilization to Overcome Malperfusion in Acute Type I Aortic Dissection.

Tsagakis K, Jánosi RA, Frey UH, Schlosser T, Chiesa R, Rassaf T, Jakob H.

Semin Thorac Cardiovasc Surg. 2018 Dec 8. pii: S1043-0679(18)30385-X. doi: 10.1053/j.semtcvs.2018.11.012. [Epub ahead of print]


Nasal microbiota and symptom persistence in acute respiratory tract infections in infants.

Neumann RP, Hilty M, Xu B, Usemann J, Korten I, Mika M, Müller L, Latzin P, Frey U.

ERJ Open Res. 2018 Dec 3;4(4). pii: 00066-2018. doi: 10.1183/23120541.00066-2018. eCollection 2018 Oct.


Dynamics of respiratory symptoms during infancy and associations with wheezing at school age.

Usemann J, Xu B, Delgado-Eckert E, Korten I, Anagnostopoulou P, Gorlanova O, Kuehni C, Röösli M, Latzin P, Frey U.

ERJ Open Res. 2018 Nov 20;4(4). pii: 00037-2018. doi: 10.1183/23120541.00037-2018. eCollection 2018 Oct.


The Swiss Paediatric Airway Cohort (SPAC).

Pedersen ESL, de Jong CCM, Ardura-Garcia C, Barben J, Casaulta C, Frey U, Jochmann A, Latzin P, Moeller A, Regamey N, Singer F, Spycher B, Sutter O, Goutaki M, Kuehni CE.

ERJ Open Res. 2018 Nov 20;4(4). pii: 00050-2018. doi: 10.1183/23120541.00050-2018. eCollection 2018 Oct.


Variability of Tidal Breathing Parameters in Preterm Infants and Associations with Respiratory Morbidity during Infancy: A Cohort Study.

Usemann J, Suter A, Zannin E, Proietti E, Fouzas S, Schulzke S, Latzin P, Frey U; BILD study group.

J Pediatr. 2019 Feb;205:61-69.e1. doi: 10.1016/j.jpeds.2018.10.002. Epub 2018 Nov 8.


Mitochondrial and Contractile Function of Human Right Atrial Tissue in Response to Remote Ischemic Conditioning.

Kleinbongard P, Gedik N, Kirca M, Stoian L, Frey U, Zandi A, Thielmann M, Jakob H, Peters J, Kamler M, Heusch G.

J Am Heart Assoc. 2018 Aug 7;7(15):e009540. doi: 10.1161/JAHA.118.009540.


Monolithic CMOS sensor platform featuring an array of 9'216 carbon-nanotube-sensor elements and low-noise, wide-bandwidth and wide-dynamic-range readout circuitry.

Dudina A, Seichepine F, Chen Y, Stettler A, Hierlemann A, Frey U.

Sens Actuators B Chem. 2019 Jan 15;279:255-266. doi: 10.1016/j.snb.2018.10.004.


Neighbourhood child population density as a proxy measure for exposure to respiratory infections in the first year of life: A validation study.

Lupatsch JE, Kreis C, Korten I, Latzin P, Frey U, Kuehni CE, Spycher BD.

PLoS One. 2018 Sep 12;13(9):e0203743. doi: 10.1371/journal.pone.0203743. eCollection 2018.


Willingness to pay and moral stance: The case of farm animal welfare in Germany.

Frey UJ, Pirscher F.

PLoS One. 2018 Aug 14;13(8):e0202193. doi: 10.1371/journal.pone.0202193. eCollection 2018. Erratum in: PLoS One. 2018 Oct 5;13(10):e0205551.


Respiratory rate in infants with cystic fibrosis throughout the first year of life and association with lung clearance index measured shortly after birth.

Korten I, Kieninger E, Yammine S, Cangiano G, Nyilas S, Anagnostopoulou P, Singer F, Kuehni CE, Regamey N, Frey U, Casaulta C, Spycher BD, Latzin P; SCILD; BILD study group.

J Cyst Fibros. 2019 Jan;18(1):118-126. doi: 10.1016/j.jcf.2018.07.002. Epub 2018 Jul 27.


Protective effects of breastfeeding on respiratory symptoms in infants with 17q21 asthma risk variants.

Gorlanova O, Illi S, Toncheva AA, Usemann J, Latzin P, Kabesch M, Dalphin JC, Lauener R, Pekkanen JR, Von Mutius E, Riedler J, Kuehni CE, Röösli M, Frey U; BILD and PASTURE study groups.

Allergy. 2018 Dec;73(12):2388-2392. doi: 10.1111/all.13568. Epub 2018 Aug 9. No abstract available.


Response of cord blood cells to environmental, hereditary and perinatal factors: A prospective birth cohort study.

Lurà MP, Gorlanova O, Müller L, Proietti E, Vienneau D, Reppucci D, Pavlovic R, Dahinden C, Röösli M, Latzin P, Frey U.

PLoS One. 2018 Jul 6;13(7):e0200236. doi: 10.1371/journal.pone.0200236. eCollection 2018.


[Point-of-Care Testing in Trauma Patients - Methods and Evidence].

Dirkmann D, Britten MW, Frey UH.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2018 Jun;53(6):440-457. doi: 10.1055/s-0043-107753. Epub 2018 Jun 26. Review. German.


CHRM3 rs2165870 polymorphism is independently associated with postoperative nausea and vomiting, but combined prophylaxis is effective.

Klenke S, de Vries GJ, Schiefer L, Seyffert N, Bachmann HS, Peters J, Frey UH.

Br J Anaesth. 2018 Jul;121(1):58-65. doi: 10.1016/j.bja.2018.02.025. Epub 2018 Apr 4.


Increased circulating microRNA-122 is associated with mortality and acute liver injury in the acute respiratory distress syndrome.

Rahmel T, Rump K, Adamzik M, Peters J, Frey UH.

BMC Anesthesiol. 2018 Jun 23;18(1):75. doi: 10.1186/s12871-018-0541-5.


Circulating miR-192 is a prognostic marker in patients with ischemic cardiomyopathy.

Klenke S, Eul S, Peters J, Neumann T, Adamzik M, Frey UH.

Future Cardiol. 2018 Jul;14(4):283-289. doi: 10.2217/fca-2017-0108. Epub 2018 Jun 21.


The GRK2 Promoter Is Regulated by Early-Growth Response Transcription Factor EGR-1.

Klenke S, Engler A, Ecker D, Ochsenfarth C, Danowski N, Peters J, Siffert W, Frey UH.

Basic Clin Pharmacol Toxicol. 2018 Dec;123(6):660-669. doi: 10.1111/bcpt.13055. Epub 2018 Jul 9.


Increased circulating microRNA-122 is a biomarker for discrimination and risk stratification in patients defined by sepsis-3 criteria.

Rahmel T, Schäfer ST, Frey UH, Adamzik M, Peters J.

PLoS One. 2018 May 21;13(5):e0197637. doi: 10.1371/journal.pone.0197637. eCollection 2018.


Acquisition of Bioelectrical Signals with Small Electrodes.

Viswam V, Obien M, Frey U, Franke F, Hierlemann A.

IEEE Biomed Circuits Syst Conf. 2018 Mar 29;2017:1-4. doi: 10.1109/BIOCAS.2017.8325216.


Glucocorticoid metabolites in newborns: A marker for traffic noise related stress?

Cantuaria ML, Usemann J, Proietti E, Blanes-Vidal V, Dick B, Flück CE, Rüedi S, Héritier H, Wunderli JM, Latzin P, Frey U, Röösli M, Vienneau D; BILD study group.

Environ Int. 2018 Aug;117:319-326. doi: 10.1016/j.envint.2018.05.002. Epub 2018 May 17.


Nasal Microbiota and Respiratory Tract Infections: The Role of Viral Detection.

Korten I, Ramsey K, Mika M, Usemann J, Frey U, Hilty M, Latzin P.

Am J Respir Crit Care Med. 2018 Mar 8. doi: 10.1164/rccm.201710-2020LE. [Epub ahead of print] No abstract available.


Patterns of paediatric end-of-life care: a chart review across different care settings in Switzerland.

Zimmermann K, Cignacco E, Engberg S, Ramelet AS, von der Weid N, Eskola K, Bergstraesser E; PELICAN Consortium, Ansari M, Aebi C, Baer R, Popovic MB, Bernet V, Brazzola P, Bucher HU, Buder R, Cagnazzo S, Dinten B, Dorsaz A, Elmer F, Enriquez R, Fahrni-Nater P, Finkbeiner G, Frey B, Frey U, Greiner J, Hassink RI, Keller S, Kretschmar O, Kroell J, Laubscher B, Leibundgut K, Malaer R, Meyer A, Stuessi C, Nelle M, Neuhaus T, Niggli F, Perrenoud G, Pfammatter JP, Plecko B, Rupf D, Sennhauser F, Stade C, Steinlin M, Stoffel L, Thomas K, Vonarburg C, von Vigier R, Wagner B, Wieland J, Wernz B.

BMC Pediatr. 2018 Feb 16;18(1):67. doi: 10.1186/s12887-018-1021-2.


Translating secondary electrospray ionization-high-resolution mass spectrometry to the clinical environment.

Singh KD, Del Miguel GV, Gaugg MT, Ibañez AJ, Zenobi R, Kohler M, Frey U, Sinues PM.

J Breath Res. 2018 Feb 7;12(2):027113. doi: 10.1088/1752-7163/aa9ee3.


Establishment of an easy and straight forward heparinase protocol to analyse circulating and myocardial tissue micro-RNA during coronary artery-bypass-graft surgery.

Engler A, Dreja F, Köberle S, Thielmann M, Peters J, Frey UH.

Sci Rep. 2018 Jan 22;8(1):1361. doi: 10.1038/s41598-018-19748-6.


Electronic monitoring of adherence to inhaled corticosteroids: an essential tool in identifying severe asthma in children.

Jochmann A, Artusio L, Jamalzadeh A, Nagakumar P, Delgado-Eckert E, Saglani S, Bush A, Frey U, Fleming LJ.

Eur Respir J. 2017 Dec 21;50(6). pii: 1700910. doi: 10.1183/13993003.00910-2017. Print 2017 Dec.


Novel magnetic resonance technique for functional imaging of cystic fibrosis lung disease.

Nyilas S, Bauman G, Sommer G, Stranzinger E, Pusterla O, Frey U, Korten I, Singer F, Casaulta C, Bieri O, Latzin P.

Eur Respir J. 2017 Dec 7;50(6). pii: 1701464. doi: 10.1183/13993003.01464-2017. Print 2017 Dec.


Elevated lung clearance index in infants with cystic fibrosis shortly after birth.

Kieninger E, Yammine S, Korten I, Anagnostopoulou P, Singer F, Frey U, Mornand A, Zanolari M, Rochat I, Trachsel D, Mueller-Suter D, Moeller A, Casaulta C, Latzin P; SCILD study group; BILD study group.

Eur Respir J. 2017 Nov 9;50(5). pii: 1700580. doi: 10.1183/13993003.00580-2017. Print 2017 Nov.


Surface electromyography for analysis of heart rate variability in preterm infants.

Jost K, Scherer S, De Angelis C, Büchler M, Datta AN, Cattin PC, Frey U, Suki B, Schulzke SM.

Physiol Meas. 2017 Dec 28;39(1):015004. doi: 10.1088/1361-6579/aa996a.


Potential humoral mediators of remote ischemic preconditioning in patients undergoing surgical coronary revascularization.

Gedik N, Kottenberg E, Thielmann M, Frey UH, Jakob H, Peters J, Heusch G, Kleinbongard P.

Sci Rep. 2017 Oct 4;7(1):12660. doi: 10.1038/s41598-017-12833-2.


After asthma: redefining airways diseases.

Pavord ID, Beasley R, Agusti A, Anderson GP, Bel E, Brusselle G, Cullinan P, Custovic A, Ducharme FM, Fahy JV, Frey U, Gibson P, Heaney LG, Holt PG, Humbert M, Lloyd CM, Marks G, Martinez FD, Sly PD, von Mutius E, Wenzel S, Zar HJ, Bush A.

Lancet. 2018 Jan 27;391(10118):350-400. doi: 10.1016/S0140-6736(17)30879-6. Epub 2017 Sep 11. Review. No abstract available.


Breath-to-breath variability of exhaled CO2 as a marker of lung dysmaturity in infancy.

Fouzas S, Theodorakopoulos I, Delgado-Eckert E, Latzin P, Frey U.

J Appl Physiol (1985). 2017 Dec 1;123(6):1563-1570. doi: 10.1152/japplphysiol.00372.2017. Epub 2017 Sep 7.


Functional phenotypes determined by fluctuation-based clustering of lung function measurements in healthy and asthmatic cohort participants.

Delgado-Eckert E, Fuchs O, Kumar N, Pekkanen J, Dalphin JC, Riedler J, Lauener R, Kabesch M, Kupczyk M, Dahlen SE, Mutius EV, Frey U; PASTURE and BIOAIR Study groups.

Thorax. 2018 Feb;73(2):107-115. doi: 10.1136/thoraxjnl-2016-209919. Epub 2017 Sep 2.


ESC Joint Working Groups on Cardiovascular Surgery and the Cellular Biology of the Heart Position Paper: Perioperative myocardial injury and infarction in patients undergoing coronary artery bypass graft surgery.

Thielmann M, Sharma V, Al-Attar N, Bulluck H, Bisleri G, Bunge JJH, Czerny M, Ferdinandy P, Frey UH, Heusch G, Holfeld J, Kleinbongard P, Kunst G, Lang I, Lentini S, Madonna R, Meybohm P, Muneretto C, Obadia JF, Perrino C, Prunier F, Sluijter JPG, Van Laake LW, Sousa-Uva M, Hausenloy DJ.

Eur Heart J. 2017 Aug 14;38(31):2392-2407. doi: 10.1093/eurheartj/ehx383. No abstract available.


A time-varying biased random walk approach to human growth.

Suki B, Frey U.

Sci Rep. 2017 Aug 10;7(1):7805. doi: 10.1038/s41598-017-07725-4.


Proteomics/phosphoproteomics of left ventricular biopsies from patients with surgical coronary revascularization and pigs with coronary occlusion/reperfusion: remote ischemic preconditioning.

Gedik N, Krüger M, Thielmann M, Kottenberg E, Skyschally A, Frey UH, Cario E, Peters J, Jakob H, Heusch G, Kleinbongard P.

Sci Rep. 2017 Aug 9;7(1):7629. doi: 10.1038/s41598-017-07883-5.


Respiratory viruses in healthy infants and infants with cystic fibrosis: a prospective cohort study.

Korten I, Kieninger E, Klenja S, Mack I, Schläpfer N, Barbani MT, Regamey N, Kuehni CE, Hilty M, Frey U, Gorgievski M, Casaulta C, Latzin P; SCILD and BILD study groups.

Thorax. 2018 Jan;73(1):13-20. doi: 10.1136/thoraxjnl-2016-209553. Epub 2017 Aug 4.


Interrupter technique in infancy: Higher airway resistance and lower short-term variability in preterm versus term infants.

Usemann J, Demann D, Anagnostopoulou P, Korten I, Gorlanova O, Schulzke S, Frey U, Latzin P.

Pediatr Pulmonol. 2017 Oct;52(10):1355-1362. doi: 10.1002/ppul.23771. Epub 2017 Aug 3.


[How Much Alarm Can the Human Being Tolerate?]

Lorenz B, Peters J, Frey UH.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2017 Jul;52(7-08):564-570. doi: 10.1055/s-0042-118618. Epub 2017 Jul 25. German.


Influence of the pneumococcal conjugate vaccines on the temporal variation of pneumococcal carriage and the nasal microbiota in healthy infants: a longitudinal analysis of a case-control study.

Mika M, Maurer J, Korten I, Allemann A, Aebi S, Brugger SD, Qi W, Frey U, Latzin P, Hilty M.

Microbiome. 2017 Jul 24;5(1):85. doi: 10.1186/s40168-017-0302-6.


Lower exhaled nitric oxide in infants with Cystic Fibrosis compared to healthy controls.

Korten I, Liechti M, Singer F, Hafen G, Rochat I, Anagnostopoulou P, Müller-Suter D, Usemann J, Moeller A, Frey U, Latzin P, Casaulta C; SCILD and BILD study group.

J Cyst Fibros. 2018 Jan;17(1):105-108. doi: 10.1016/j.jcf.2017.05.005. Epub 2017 Jul 14.


Dynamics and complexity of body temperature in preterm infants nursed in incubators.

Jost K, Pramana I, Delgado-Eckert E, Kumar N, Datta AN, Frey U, Schulzke SM.

PLoS One. 2017 Apr 27;12(4):e0176670. doi: 10.1371/journal.pone.0176670. eCollection 2017.

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