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Items: 1 to 50 of 378

1.

A cardiac α-actin (ACTC1) p. Gly247Asp mutation inhibits SRF-signaling in vitro in neonatal rat cardiomyocytes.

Rangrez AY, Kilian L, Stiebeling K, Dittmann S, Schulze-Bahr E, Frey N, Frank D.

Biochem Biophys Res Commun. 2019 Aug 18. pii: S0006-291X(19)31604-3. doi: 10.1016/j.bbrc.2019.08.081. [Epub ahead of print]

PMID:
31434612
2.

Cardiac α-Actin (ACTC1) Gene Mutation Causes Atrial-Septal Defects Associated With Late-Onset Dilated Cardiomyopathy.

Frank D, Yusuf Rangrez A, Friedrich C, Dittmann S, Stallmeyer B, Yadav P, Bernt A, Schulze-Bahr E, Borlepawar A, Zimmermann WH, Peischard S, Seebohm G, Linke WA, Baba HA, Krüger M, Unger A, Usinger P, Frey N, Schulze-Bahr E.

Circ Genom Precis Med. 2019 Aug;12(8):e002491. doi: 10.1161/CIRCGEN.119.002491. Epub 2019 Aug 20.

PMID:
31430208
3.

Caseload management and outcome of patients with aortic stenosis in primary/secondary versus tertiary care settings-design of the IMPULSE enhanced registry.

Rudolph TK, Messika-Zeitoun D, Frey N, Lutz M, Krapf L, Passefort S, Fryearson J, Simpson H, Mortensen K, Rehse S, Tiroke A, Dodos F, Mies F, Pohlmann C, Kurucova J, Thoenes M, Bramlage P, Steeds RP.

Open Heart. 2019 Jul 21;6(2):e001019. doi: 10.1136/openhrt-2019-001019. eCollection 2019.

4.

Symptoms, disease severity and treatment of adults with a new diagnosis of severe aortic stenosis.

Frey N, Steeds RP, Rudolph TK, Thambyrajah J, Serra A, Schulz E, Maly J, Aiello M, Lloyd G, Bortone AS, Hauptmann KE, Clerici A, Delle Karth G, Rieber J, Indorfi C, Mancone M, Belle L, Lauten A, Arnold M, Bouma BJ, Lutz M, Pohlmann C, Kurucova J, Thoenes M, Bramlage P, Messika-Zeitoun D; IMPULSE registry group.

Heart. 2019 Jul 13. pii: heartjnl-2019-314940. doi: 10.1136/heartjnl-2019-314940. [Epub ahead of print]

PMID:
31302639
5.

Laccaria bicolor MiSSP8 is a small-secreted protein decisive for the establishment of the ectomycorrhizal symbiosis.

Pellegrin C, Daguerre Y, Ruytinx J, Guinet F, Kemppainen M, Frey NFD, Puech-Pagès V, Hecker A, Pardo AG, Martin FM, Veneault-Fourrey C.

Environ Microbiol. 2019 Jul 1. doi: 10.1111/1462-2920.14727. [Epub ahead of print]

PMID:
31260142
6.

Engineering Zero-Dimensional Quantum Confinement in Transition-Metal Dichalcogenide Heterostructures.

Price CC, Frey NC, Jariwala D, Shenoy VB.

ACS Nano. 2019 Jul 23;13(7):8303-8311. doi: 10.1021/acsnano.9b03716. Epub 2019 Jun 26.

PMID:
31241897
7.

Clinical and Angiographic Outcomes With a Novel Radiopaque Sirolimus-Eluting Bioresorbable Vascular Scaffold.

Chevalier B, Abizaid A, Carrié D, Frey N, Lutz M, Weber-Albers J, Dudek D, Weng SC, Akodad M, Anderson J, Stone GW.

Circ Cardiovasc Interv. 2019 Jun;12(6):e007283. doi: 10.1161/CIRCINTERVENTIONS.118.007283. Epub 2019 Jun 10.

PMID:
31177821
8.

The orphan receptor GPRC5B modulates inflammatory and fibrotic pathways in cardiac fibroblasts and mice hearts.

von Samson-Himmelstjerna FA, Freundt G, Nitz JT, Stelter F, Luedde M, Wieland T, Frey N, Hippe HJ.

Biochem Biophys Res Commun. 2019 Jul 5;514(4):1198-1203. doi: 10.1016/j.bbrc.2019.05.038. Epub 2019 May 16.

PMID:
31104767
9.

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Transplantation (ASBMT).

Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill JA, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK.

Bone Marrow Transplant. 2019 May 15. doi: 10.1038/s41409-019-0451-2. [Epub ahead of print]

PMID:
31092900
10.

Pharmacokinetics, exposure, efficacy and safety of obinutuzumab in rituximab-refractory follicular lymphoma patients in the GADOLIN phase III study.

Gibiansky E, Gibiansky L, Buchheit V, Frey N, Brewster M, Fingerle-Rowson G, Jamois C.

Br J Clin Pharmacol. 2019 May 3. doi: 10.1111/bcp.13974. [Epub ahead of print]

PMID:
31050355
11.

Mechanical performance and healing patterns of the novel sirolimus-eluting bioresorbable Fantom scaffold: 6-month and 9-month follow-up by optical coherence tomography in the FANTOM II study.

Simonsen JK, Holck EN, Carrié D, Frey N, Lutz M, Weber-Albers J, Dudek D, Chevalier B, Daemen J, Dijkstra J, Fox Maule C, Neghabat O, Lassen JF, Anderson J, Christiansen EH, Abizaid A, Holm NR.

Open Heart. 2019 Feb 28;6(1):e000941. doi: 10.1136/openhrt-2018-000941. eCollection 2019.

12.

Hodgkin lymphoma patients have an increased incidence of idiopathic acquired aplastic anemia.

Linaburg T, Davis AR, Frey NV, Khawaja MR, Landsburg DJ, Schuster SJ, Svoboda J, Li Y, Borovskiy Y, Olson TS, Bagg A, Hexner EO, Babushok DV.

PLoS One. 2019 Apr 5;14(4):e0215021. doi: 10.1371/journal.pone.0215021. eCollection 2019.

13.

From waterfall plots to spaghetti plots in early oncology clinical development.

Mercier F, Consalvo N, Frey N, Phipps A, Ribba B.

Pharm Stat. 2019 Apr 3. doi: 10.1002/pst.1944. [Epub ahead of print]

PMID:
30942559
14.

miR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years.

Tacke F, Spehlmann ME, Vucur M, Benz F, Luedde M, Cardenas DV, Roy S, Loosen S, Hippe HJ, Frey N, Trautwein C, Koch A, Roderburg C, Luedde T.

Mediators Inflamm. 2019 Feb 24;2019:6714080. doi: 10.1155/2019/6714080. eCollection 2019.

15.
16.

Nabilone for Chronic Pain Management: A Review of Clinical Effectiveness and Guidelines – An Update [Internet].

McGolrick D, Frey N.

Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2018 Nov 2.

17.
18.

Role of obinutuzumab exposure on clinical outcome of follicular lymphoma treated with first-line immunochemotherapy.

Jamois C, Gibiansky E, Gibiansky L, Buchheit V, Sahin D, Cartron G, Marcus R, Hiddemann W, Seymour JF, Strefford JC, Hargreaves CE, Meneses-Lorente G, Frey N, Fingerle-Rowson G.

Br J Clin Pharmacol. 2019 Jul;85(7):1495-1506. doi: 10.1111/bcp.13920. Epub 2019 May 17.

19.

A Gene Expression Test to Assess the Likelihood of Obstructive Coronary Artery Disease.

Mason J, Frey N.

CADTH Issues in Emerging Health Technologies. Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016-. 170.

20.
21.
22.
23.

Prediction of Synthesis of 2D Metal Carbides and Nitrides (MXenes) and Their Precursors with Positive and Unlabeled Machine Learning.

Frey NC, Wang J, Vega Bellido GI, Anasori B, Gogotsi Y, Shenoy VB.

ACS Nano. 2019 Mar 26;13(3):3031-3041. doi: 10.1021/acsnano.8b08014. Epub 2019 Mar 7.

PMID:
30830760
24.

Rho-family GTPase 1 (Rnd1) is a biomechanical stress-sensitive activator of cardiomyocyte hypertrophy.

Kluge A, Rangrez AY, Kilian LS, Pott J, Bernt A, Frauen R, Rohrbeck A, Frey N, Frank D.

J Mol Cell Cardiol. 2019 Apr;129:130-143. doi: 10.1016/j.yjmcc.2019.01.028. Epub 2019 Feb 21.

PMID:
30797814
25.

Chimeric antigen receptor T cells for acute lymphoblastic leukemia.

Frey NV.

Am J Hematol. 2019 May;94(S1):S24-S27. doi: 10.1002/ajh.25442. Epub 2019 Mar 22. Review.

PMID:
30784101
26.

Eltrombopag treatment during induction chemotherapy for acute myeloid leukaemia: a randomised, double-blind, phase 2 study.

Frey N, Jang JH, Szer J, Illés Á, Kim HJ, Ram R, Chong BH, Rowe JM, Borisenkova E, Liesveld J, Winer ES, Cherfi A, Aslanis V, Ghaznawi F, Strickland S.

Lancet Haematol. 2019 Mar;6(3):e122-e131. doi: 10.1016/S2352-3026(18)30231-X. Epub 2019 Jan 29.

PMID:
30704923
27.

Cardio-toxicity of checkpoint inhibitors.

Müller OJ, Spehlmann ME, Frey N.

J Thorac Dis. 2018 Dec;10(Suppl 35):S4400-S4404. doi: 10.21037/jtd.2018.12.78. Review.

28.

A retrospective study of conscious sedation versus general anaesthesia in patients scheduled for transfemoral aortic valve implantation: A single center experience.

Renner J, Tesdorpf A, Freitag-Wolf S, Francksen H, Petzina R, Lutter G, Frey N, Frank D.

Health Sci Rep. 2018 Nov 1;2(1):e95. doi: 10.1002/hsr2.95. eCollection 2019 Jan.

29.

Periprocedural Changes of NT-proBNP Are Associated With Survival After Transcatheter Aortic Valve Implantation.

Seoudy H, Frank J, Neu M, Güßefeld N, Klaus Y, Freitag-Wolf S, Lambers M, Lutter G, Dempfle A, Rangrez AY, Kuhn C, Frey N, Frank D.

J Am Heart Assoc. 2019 Feb 5;8(3):e010876. doi: 10.1161/JAHA.118.010876.

30.

Universal fluctuations in growth dynamics of economic systems.

Frey NC, Matin S, Stanley HE, Salinger MA.

Sci Rep. 2019 Jan 24;9(1):713. doi: 10.1038/s41598-018-38088-z.

31.

The DEDICATE Trial: An independent all-comers trial of transcatheter aortic valve implantation vs. surgical aortic valve replacement in patients at low to intermediate operative risk is recruiting patients.

Seiffert M, Walther T, Hamm C, Falk V, Frey N, Thiele H, Hagl C, Landmesser U, Borger M, Massberg S, Reichenspurner H, Baumgartner H, Blankenberg S, Cremer J.

Eur Heart J. 2019 Jan 21;40(4):331-333. doi: 10.1093/eurheartj/ehy851. No abstract available.

PMID:
30668699
32.

Surface-Engineered MXenes: Electric Field Control of Magnetism and Enhanced Magnetic Anisotropy.

Frey NC, Bandyopadhyay A, Kumar H, Anasori B, Gogotsi Y, Shenoy VB.

ACS Nano. 2019 Mar 26;13(3):2831-2839. doi: 10.1021/acsnano.8b09201. Epub 2019 Jan 23.

PMID:
30653916
33.

Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response.

Binder P, Wang S, Radu M, Zin M, Collins L, Khan S, Li Y, Sekeres K, Humphreys N, Swanton E, Reid A, Pu F, Oceandy D, Guan K, Hille SS, Frey N, Müller OJ, Cartwright EJ, Chernoff J, Wang X, Liu W.

Circ Res. 2019 Mar;124(5):696-711. doi: 10.1161/CIRCRESAHA.118.312829.

34.

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells.

Lee DW, Santomasso BD, Locke FL, Ghobadi A, Turtle CJ, Brudno JN, Maus MV, Park JH, Mead E, Pavletic S, Go WY, Eldjerou L, Gardner RA, Frey N, Curran KJ, Peggs K, Pasquini M, DiPersio JF, van den Brink MRM, Komanduri KV, Grupp SA, Neelapu SS.

Biol Blood Marrow Transplant. 2019 Apr;25(4):625-638. doi: 10.1016/j.bbmt.2018.12.758. Epub 2018 Dec 25. Review.

35.

Cytokine Release Syndrome with Chimeric Antigen Receptor T Cell Therapy.

Frey N, Porter D.

Biol Blood Marrow Transplant. 2019 Apr;25(4):e123-e127. doi: 10.1016/j.bbmt.2018.12.756. Epub 2018 Dec 23. Review.

PMID:
30586620
36.

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation.

Kansagra AJ, Frey NV, Bar M, Laetsch TW, Carpenter PA, Savani BN, Heslop HE, Bollard CM, Komanduri KV, Gastineau DA, Chabannon C, Perales MA, Hudecek M, Aljurf M, Andritsos L, Barrett JA, Bachanova V, Bonini C, Ghobadi A, Gill SI, Hill J, Kenderian S, Kebriaei P, Nagler A, Maloney D, Liu HD, Shah NN, Kharfan-Dabaja MA, Shpall EJ, Mufti GJ, Johnston L, Jacoby E, Bazarbachi A, DiPersio JF, Pavletic SZ, Porter DL, Grupp SA, Sadelain M, Litzow MR, Mohty M, Hashmi SK.

Biol Blood Marrow Transplant. 2019 Mar;25(3):e76-e85. doi: 10.1016/j.bbmt.2018.12.068. Epub 2018 Dec 18.

PMID:
30576834
37.

Incidence and impact of prosthesis-patient mismatch following transcatheter aortic valve implantation.

Seoudy H, Güßefeld N, Frank J, Freitag-Wolf S, Lutter G, Eden M, Rangrez AY, Kuhn C, Frey N, Frank D.

Clin Res Cardiol. 2019 Jun;108(6):660-668. doi: 10.1007/s00392-018-1394-0. Epub 2018 Nov 19.

PMID:
30456463
38.

Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.

Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, González Maldonado S, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, Jungmann A, Weis TM, Kreußer JS, Gröne HJ, Backs J, Schatz P, Katus HA, Frey N.

Cardiovasc Res. 2019 Jul 1;115(8):1296-1305. doi: 10.1093/cvr/cvy274.

PMID:
30418544
39.

Early positron emission tomography/computed tomography as a predictor of response after CTL019 chimeric antigen receptor -T-cell therapy in B-cell non-Hodgkin lymphomas.

Shah NN, Nagle SJ, Torigian DA, Farwell MD, Hwang WT, Frey N, Nasta SD, Landsburg D, Mato A, June CH, Schuster SJ, Porter DL, Svoboda J.

Cytotherapy. 2018 Dec;20(12):1415-1418. doi: 10.1016/j.jcyt.2018.10.003. Epub 2018 Oct 29.

PMID:
30385043
40.

The functional consequences of sodium channel NaV 1.8 in human left ventricular hypertrophy.

Ahmad S, Tirilomis P, Pabel S, Dybkova N, Hartmann N, Molina CE, Tirilomis T, Kutschka I, Frey N, Maier LS, Hasenfuss G, Streckfuss-Bömeke K, Sossalla S.

ESC Heart Fail. 2019 Feb;6(1):154-163. doi: 10.1002/ehf2.12378. Epub 2018 Oct 30.

41.

Impact of thrombin injection in femoral artery pseudoaneurysms with AV-fistula.

Müller OJ, Frey N.

Vasa. 2018 Oct;47(6):437-438. doi: 10.1024/0301-1526/a000734. No abstract available.

42.

Pediatric Dosing of Ganciclovir and Valganciclovir: How Model-Based Simulations Can Prevent Underexposure and Potential Treatment Failure.

Jorga K, Reigner B, Chavanne C, Alvaro G, Frey N.

CPT Pharmacometrics Syst Pharmacol. 2019 Mar;8(3):167-176. doi: 10.1002/psp4.12363. Epub 2018 Dec 18.

43.

Serum levels of kisspeptin are elevated in critically ill patients.

Luedde M, Spehlmann ME, Hippe HJ, Loosen SH, Roy S, Vargas Cardenas D, Vucur M, Frey N, Koch A, Luedde T, Trautwein C, Tacke F, Roderburg C.

PLoS One. 2018 Oct 17;13(10):e0206064. doi: 10.1371/journal.pone.0206064. eCollection 2018.

44.

Insights into permanent pacemaker implantation following TAVR in a real-world cohort.

Tichelbäcker T, Bergau L, Puls M, Friede T, Mütze T, Maier LS, Frey N, Hasenfuß G, Zabel M, Jacobshagen C, Sossalla S.

PLoS One. 2018 Oct 17;13(10):e0204503. doi: 10.1371/journal.pone.0204503. eCollection 2018.

45.

Extended CCR5 Blockade for Graft-versus-Host Disease Prophylaxis Improves Outcomes of Reduced-Intensity Unrelated Donor Hematopoietic Cell Transplantation: A Phase II Clinical Trial.

Reshef R, Ganetsky A, Acosta EP, Blauser R, Crisalli L, McGraw J, Frey NV, Hexner EO, Hoxie JA, Loren AW, Luger SM, Mangan J, Stadtmauer EA, Mick R, Vonderheide RH, Porter DL.

Biol Blood Marrow Transplant. 2019 Mar;25(3):515-521. doi: 10.1016/j.bbmt.2018.09.034. Epub 2018 Oct 10.

PMID:
30315941
46.

Prospective, large-scale multicenter trial for the use of drug-coated balloons in coronary lesions: The DCB-only All-Comers Registry.

Rosenberg M, Waliszewski M, Chin K, Ahmad WAW, Caramanno G, Milazzo D, Nuruddin AA, Liew HB, Maskon O, Aubry P, Poyet R, Frey N.

Catheter Cardiovasc Interv. 2019 Feb 1;93(2):181-188. doi: 10.1002/ccd.27724. Epub 2018 Oct 2.

PMID:
30280482
47.

Editorial commentary: Epithelial-to-Mesenchymal transition and G protein-coupled receptors: A novel possibility for cardiac regeneration?

Borlepawar A, Frey N, Frank D.

Trends Cardiovasc Med. 2019 May;29(4):205-206. doi: 10.1016/j.tcm.2018.09.008. Epub 2018 Sep 18. No abstract available.

PMID:
30268649
48.

Oral Vancomycin Prophylaxis Is Highly Effective in Preventing Clostridium difficile Infection in Allogeneic Hematopoietic Cell Transplant Recipients.

Ganetsky A, Han JH, Hughes ME, Babushok DV, Frey NV, Gill SI, Hexner EO, Loren AW, Luger SM, Mangan JK, Martin ME, Smith J, Freyer CW, Gilmar C, Schuster M, Stadtmauer EA, Porter DL.

Clin Infect Dis. 2019 May 30;68(12):2003-2009. doi: 10.1093/cid/ciy822.

PMID:
30256954
49.
50.

Progress in heart failure treatment in Germany.

Luedde M, Spehlmann ME, Frey N.

Clin Res Cardiol. 2018 Aug;107(Suppl 2):105-113. doi: 10.1007/s00392-018-1317-0. Epub 2018 Jul 2. Review.

PMID:
29968196

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