Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 63

1.

A direct comparison of mouse and human intestinal development using epithelial gene expression patterns.

Stanford AH, Gong H, Noonan M, Lewis AN, Gong Q, Lanik WE, Hsieh JJ, Lueschow SR, Frey MR, Good M, McElroy SJ.

Pediatr Res. 2019 Jun 26. doi: 10.1038/s41390-019-0472-y. [Epub ahead of print]

PMID:
31242501
2.

Trefoil factor 2 activation of CXCR4 requires calcium mobilization to drive epithelial repair in gastric organoids.

Engevik KA, Hanyu H, Matthis AL, Zhang T, Frey MR, Oshima Y, Aihara E, Montrose MH.

J Physiol. 2019 May;597(10):2673-2690. doi: 10.1113/JP277259. Epub 2019 Apr 14.

PMID:
30912855
3.

Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury.

Jones JC, Brindley CD, Elder NH, Myers MG Jr, Rajala MW, Dekaney CM, McNamee EN, Frey MR, Shroyer NF, Dempsey PJ.

Cell Mol Gastroenterol Hepatol. 2019;7(3):533-554. doi: 10.1016/j.jcmgh.2018.11.004. Epub 2018 Nov 27.

4.

Discordant roles for FGF ligands in lung branching morphogenesis between human and mouse.

Danopoulos S, Thornton ME, Grubbs BH, Frey MR, Warburton D, Bellusci S, Al Alam D.

J Pathol. 2019 Feb;247(2):254-265. doi: 10.1002/path.5188. Epub 2018 Dec 13.

PMID:
30357827
5.

Short-term and long-term human or mouse organoid units generate tissue-engineered small intestine without added signalling molecules.

Hou X, Chang DF, Trecartin A, Barthel ER, Schlieve CR, Frey MR, Fowler KL, Grikscheit TC.

Exp Physiol. 2018 Dec;103(12):1633-1644. doi: 10.1113/EP086990. Epub 2018 Nov 2.

PMID:
30232817
6.

Colon Cancers Get a Negative (Selection) Attitude.

Frey MR.

Cell Mol Gastroenterol Hepatol. 2018 Jul 20;6(3):349. doi: 10.1016/j.jcmgh.2018.06.009. eCollection 2018. No abstract available.

7.

Ursodeoxycholic acid protects against intestinal barrier breakdown by promoting enterocyte migration via EGFR- and COX-2-dependent mechanisms.

Golden JM, Escobar OH, Nguyen MVL, Mallicote MU, Kavarian P, Frey MR, Gayer CP.

Am J Physiol Gastrointest Liver Physiol. 2018 Aug 1;315(2):G259-G271. doi: 10.1152/ajpgi.00354.2017. Epub 2018 Apr 19.

8.

Celiac Disease.

Murray JA, Frey MR, Oliva-Hemker M.

Gastroenterology. 2018 Jun;154(8):2005-2008. doi: 10.1053/j.gastro.2017.12.026. Epub 2018 Mar 15. Review. No abstract available.

9.

Bacterial Encroachment in Metabolic Syndrome: Too Much Togetherness?

Frey MR.

Cell Mol Gastroenterol Hepatol. 2017 Jun 13;4(2):324-325. doi: 10.1016/j.jcmgh.2017.05.006. eCollection 2017 Sep. No abstract available.

10.

SERCA directs cell migration and branching across species and germ layers.

Bower DV, Lansdale N, Navarro S, Truong TV, Bower DJ, Featherstone NC, Connell MG, Al Alam D, Frey MR, Trinh LA, Fernandez GE, Warburton D, Fraser SE, Bennett D, Jesudason EC.

Biol Open. 2017 Oct 15;6(10):1458-1471. doi: 10.1242/bio.026039.

11.

Prolonged Absence of Mechanoluminal Stimulation in Human Intestine Alters the Transcriptome and Intestinal Stem Cell Niche.

Wieck MM, Schlieve CR, Thornton ME, Fowler KL, Isani M, Grant CN, Hilton AE, Hou X, Grubbs BH, Frey MR, Grikscheit TC.

Cell Mol Gastroenterol Hepatol. 2017 Jan 24;3(3):367-388.e1. doi: 10.1016/j.jcmgh.2016.12.008. eCollection 2017 May.

12.

The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.

Almohazey D, Lo YH, Vossler CV, Simmons AJ, Hsieh JJ, Bucar EB, Schumacher MA, Hamilton KE, Lau KS, Shroyer NF, Frey MR.

Cell Death Differ. 2017 May;24(5):855-865. doi: 10.1038/cdd.2017.27. Epub 2017 Mar 17.

13.

ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation.

Schumacher MA, Hedl M, Abraham C, Bernard JK, Lozano PR, Hsieh JJ, Almohazey D, Bucar EB, Punit S, Dempsey PJ, Frey MR.

Cell Death Dis. 2017 Feb 23;8(2):e2622. doi: 10.1038/cddis.2017.42.

14.

Disease-Associated Microbial Communities in Healthy Relatives: A Bacteria-Filled Crystal Ball?

Frey MR.

Cell Mol Gastroenterol Hepatol. 2016 Sep 24;2(6):710-711. doi: 10.1016/j.jcmgh.2016.09.005. eCollection 2016 Nov. No abstract available.

15.

Epidermal growth factor suppresses intestinal epithelial cell shedding through a MAPK-dependent pathway.

Miguel JC, Maxwell AA, Hsieh JJ, Harnisch LC, Al Alam D, Polk DB, Lien CL, Watson AJ, Frey MR.

J Cell Sci. 2017 Jan 1;130(1):90-96. doi: 10.1242/jcs.182584. Epub 2016 Mar 29.

16.

Intrauterine Growth Restriction Alters Mouse Intestinal Architecture during Development.

Fung CM, White JR, Brown AS, Gong H, Weitkamp JH, Frey MR, McElroy SJ.

PLoS One. 2016 Jan 8;11(1):e0146542. doi: 10.1371/journal.pone.0146542. eCollection 2016.

17.

Bile acids regulate intestinal cell proliferation by modulating EGFR and FXR signaling.

Dossa AY, Escobar O, Golden J, Frey MR, Ford HR, Gayer CP.

Am J Physiol Gastrointest Liver Physiol. 2016 Jan 15;310(2):G81-92. doi: 10.1152/ajpgi.00065.2015. Epub 2015 Nov 25.

18.

Regenerating Reputations: Are Wnt and Myc the Good Guys After All?

Frey MR.

Dig Dis Sci. 2016 Feb;61(2):327-9. doi: 10.1007/s10620-015-3947-7. No abstract available.

PMID:
26520110
19.

Increased alveolar soluble annexin V promotes lung inflammation and fibrosis.

Buckley S, Shi W, Xu W, Frey MR, Moats R, Pardo A, Selman M, Warburton D.

Eur Respir J. 2015 Nov;46(5):1417-29. doi: 10.1183/09031936.00002115. Epub 2015 Jul 9.

20.

Adult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration.

Schall KA, Holoyda KA, Grant CN, Levin DE, Torres ER, Maxwell A, Pollack HA, Moats RA, Frey MR, Darehzereshki A, Al Alam D, Lien C, Grikscheit TC.

Am J Physiol Gastrointest Liver Physiol. 2015 Aug 1;309(3):G135-45. doi: 10.1152/ajpgi.00311.2014. Epub 2015 Jun 18.

21.

ERBB4 is over-expressed in human colon cancer and enhances cellular transformation.

Williams CS, Bernard JK, Demory Beckler M, Almohazey D, Washington MK, Smith JJ, Frey MR.

Carcinogenesis. 2015 Jul;36(7):710-8. doi: 10.1093/carcin/bgv049. Epub 2015 Apr 27.

22.

Altered gut microbial energy and metabolism in children with non-alcoholic fatty liver disease.

Michail S, Lin M, Frey MR, Fanter R, Paliy O, Hilbush B, Reo NV.

FEMS Microbiol Ecol. 2015 Feb;91(2):1-9. doi: 10.1093/femsec/fiu002. Epub 2014 Dec 5.

23.

Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine.

Al Alam D, Danopoulos S, Schall K, Sala FG, Almohazey D, Fernandez GE, Georgia S, Frey MR, Ford HR, Grikscheit T, Bellusci S.

Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15;308(8):G678-90. doi: 10.1152/ajpgi.00158.2014. Epub 2015 Feb 26.

24.

Tumor necrosis factor induces developmental stage-dependent structural changes in the immature small intestine.

Brown KS, Gong H, Frey MR, Pope B, Golden M, Martin K, Obey M, McElroy SJ.

Mediators Inflamm. 2014;2014:852378. doi: 10.1155/2014/852378. Epub 2014 Aug 27.

25.

The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis.

McElroy SJ, Castle SL, Bernard JK, Almohazey D, Hunter CJ, Bell BA, Al Alam D, Wang L, Ford HR, Frey MR.

Am J Pathol. 2014 Oct;184(10):2768-78. doi: 10.1016/j.ajpath.2014.06.015. Epub 2014 Sep 9.

26.

ErbB receptors and their growth factor ligands in pediatric intestinal inflammation.

Frey MR, Brent Polk D.

Pediatr Res. 2014 Jan;75(1-2):127-32. doi: 10.1038/pr.2013.210. Epub 2013 Nov 6. Review.

27.

A mouse model of pathological small intestinal epithelial cell apoptosis and shedding induced by systemic administration of lipopolysaccharide.

Williams JM, Duckworth CA, Watson AJ, Frey MR, Miguel JC, Burkitt MD, Sutton R, Hughes KR, Hall LJ, Caamaño JH, Campbell BJ, Pritchard DM.

Dis Model Mech. 2013 Nov;6(6):1388-99. doi: 10.1242/dmm.013284. Epub 2013 Aug 15.

28.

Neuregulin-4 is a survival factor for colon epithelial cells both in culture and in vivo.

Bernard JK, McCann SP, Bhardwaj V, Washington MK, Frey MR.

J Biol Chem. 2012 Nov 16;287(47):39850-8. doi: 10.1074/jbc.M112.400846. Epub 2012 Oct 2.

29.

FGF9-Pitx2-FGF10 signaling controls cecal formation in mice.

Al Alam D, Sala FG, Baptista S, Galzote R, Danopoulos S, Tiozzo C, Gage P, Grikscheit T, Warburton D, Frey MR, Bellusci S.

Dev Biol. 2012 Sep 15;369(2):340-8. doi: 10.1016/j.ydbio.2012.07.008. Epub 2012 Jul 20.

30.

TNF-α converting enzyme-mediated ErbB4 transactivation by TNF promotes colonic epithelial cell survival.

Hilliard VC, Frey MR, Dempsey PJ, Peek RM Jr, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G338-46. doi: 10.1152/ajpgi.00057.2011. Epub 2011 May 26.

31.

Specific epidermal growth factor receptor autophosphorylation sites promote mouse colon epithelial cell chemotaxis and restitution.

Yamaoka T, Frey MR, Dise RS, Bernard JK, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G368-76. doi: 10.1152/ajpgi.00327.2010. Epub 2011 May 26.

32.

TNF transactivation of EGFR stimulates cytoprotective COX-2 expression in gastrointestinal epithelial cells.

Hobbs SS, Goettel JA, Liang D, Yan F, Edelblum KL, Frey MR, Mullane MT, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G220-9. doi: 10.1152/ajpgi.00383.2010. Epub 2011 May 12.

33.

STAT6 activation in ulcerative colitis: a new target for prevention of IL-13-induced colon epithelial cell dysfunction.

Rosen MJ, Frey MR, Washington MK, Chaturvedi R, Kuhnhein LA, Matta P, Revetta FL, Wilson KT, Polk DB.

Inflamm Bowel Dis. 2011 Nov;17(11):2224-34. doi: 10.1002/ibd.21628. Epub 2011 Feb 9.

34.

Sprouty keeps bowel kinases regular in colon cancer, while miR-21 targets Sprouty.

Frey MR, Carraro G, Batra RK, Polk DB, Warburton D.

Cancer Biol Ther. 2011 Jan 1;11(1):122-4. Epub 2011 Jan 1. No abstract available.

PMID:
21124074
35.

ErbB4 promotes cyclooxygenase-2 expression and cell survival in colon epithelial cells.

Frey MR, Hilliard VC, Mullane MT, Polk DB.

Lab Invest. 2010 Oct;90(10):1415-24. doi: 10.1038/labinvest.2010.117. Epub 2010 Jun 28.

36.

Helicobacter pylori regulates cellular migration and apoptosis by activation of phosphatidylinositol 3-kinase signaling.

Nagy TA, Frey MR, Yan F, Israel DA, Polk DB, Peek RM Jr.

J Infect Dis. 2009 Mar 1;199(5):641-51. doi: 10.1086/596660.

37.

Clinical scale expanded adult pluripotent stem cells prevent graft-versus-host disease.

Kovacsovics-Bankowski M, Streeter PR, Mauch KA, Frey MR, Raber A, van't Hof W, Deans R, Maziarz RT.

Cell Immunol. 2009;255(1-2):55-60. doi: 10.1016/j.cellimm.2008.10.004. Epub 2008 Nov 20.

PMID:
19022422
38.

The ErbB4 growth factor receptor is required for colon epithelial cell survival in the presence of TNF.

Frey MR, Edelblum KL, Mullane MT, Liang D, Polk DB.

Gastroenterology. 2009 Jan;136(1):217-26. doi: 10.1053/j.gastro.2008.09.023. Epub 2008 Sep 25.

39.

Tumor necrosis factor inhibits ligand-stimulated EGF receptor activation through a TNF receptor 1-dependent mechanism.

McElroy SJ, Frey MR, Yan F, Edelblum KL, Goettel JA, John S, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G285-93. doi: 10.1152/ajpgi.00425.2007. Epub 2008 May 8.

40.

Therapeutic pathways of adult stem cell repair.

Ting AE, Mays RW, Frey MR, Hof WV, Medicetty S, Deans R.

Crit Rev Oncol Hematol. 2008 Jan;65(1):81-93. Epub 2007 Nov 26. Review.

PMID:
18032062
41.

Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration.

Dise RS, Frey MR, Whitehead RH, Polk DB.

Am J Physiol Gastrointest Liver Physiol. 2008 Jan;294(1):G276-85. Epub 2007 Nov 8.

42.

Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation.

Chen X, Abair TD, Ibanez MR, Su Y, Frey MR, Dise RS, Polk DB, Singh AB, Harris RC, Zent R, Pozzi A.

Mol Cell Biol. 2007 May;27(9):3313-26. Epub 2007 Mar 5.

43.

p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration.

Frey MR, Dise RS, Edelblum KL, Polk DB.

EMBO J. 2006 Dec 13;25(24):5683-92. Epub 2006 Nov 30.

44.

Cysteine-rich domains of muc3 intestinal mucin promote cell migration, inhibit apoptosis, and accelerate wound healing.

Ho SB, Dvorak LA, Moor RE, Jacobson AC, Frey MR, Corredor J, Polk DB, Shekels LL.

Gastroenterology. 2006 Nov;131(5):1501-17. Epub 2006 Sep 9.

PMID:
17101324
45.

Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling.

Frey MR, Golovin A, Polk DB.

J Biol Chem. 2004 Oct 22;279(43):44513-21. Epub 2004 Aug 16.

46.

Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells.

Frey MR, Clark JA, Bateman NW, Kazanietz MG, Black AR, Black JD.

Biochem Pharmacol. 2004 May 15;67(10):1873-86.

PMID:
15130764
47.

Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells.

Clark JA, Black AR, Leontieva OV, Frey MR, Pysz MA, Kunneva L, Woloszynska-Read A, Roy D, Black JD.

J Biol Chem. 2004 Mar 5;279(10):9233-47. Epub 2003 Dec 11.

48.

SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta.

Narayanan U, Ospina JK, Frey MR, Hebert MD, Matera AG.

Hum Mol Genet. 2002 Jul 15;11(15):1785-95.

49.

RNA-mediated interaction of Cajal bodies and U2 snRNA genes.

Frey MR, Matera AG.

J Cell Biol. 2001 Aug 6;154(3):499-509.

50.

Supplemental Content

Support Center