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Items: 1 to 50 of 201

1.

Outcomes of endoscopic submucosal dissection (ESD) during live endoscopy events (LEE) - a 13-year follow-up.

Ebigbo A, Freund S, Probst A, Römmele C, Gölder SK, Frauenschuh J, Marienhagen J, Messmann H.

Endosc Int Open. 2019 Dec;7(12):E1723-E1728. doi: 10.1055/a-1035-9240. Epub 2019 Dec 10.

2.

[Purtscher's retinopathy as a complication to a cemented resection tumour prosthesis].

Freund SS, Stoltz RK, Bek T, Keller J, Baad-Hansen T.

Ugeskr Laeger. 2019 Oct 28;181(44). pii: V02190096. Danish.

PMID:
31791468
3.

Transoid-to-Cisoid Conformation Changes of Single Molecules on Surfaces Triggered by Metal Coordination.

Freund S, Pawlak R, Moser L, Hinaut A, Steiner R, Marinakis N, Constable EC, Meyer E, Housecroft CE, Glatzel T.

ACS Omega. 2018 Oct 9;3(10):12851-12856. doi: 10.1021/acsomega.8b01792. eCollection 2018 Oct 31.

4.

Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo Form of the c-MYC:MAX bHLHZip Complex Reveal a Helical Basic Region in the Absence of DNA.

Sammak S, Hamdani N, Gorrec F, Allen MD, Freund SMV, Bycroft M, Zinzalla G.

Biochemistry. 2019 Jul 23;58(29):3144-3154. doi: 10.1021/acs.biochem.9b00296. Epub 2019 Jul 11.

5.

Comparing a porphyrin- and a coumarin-based dye adsorbed on NiO(001).

Freund S, Hinaut A, Marinakis N, Constable EC, Meyer E, Housecroft CE, Glatzel T.

Beilstein J Nanotechnol. 2019 Apr 15;10:874-881. doi: 10.3762/bjnano.10.88. eCollection 2019.

6.

Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.

Kargas V, Castro-Hartmann P, Escudero-Urquijo N, Dent K, Hilcenko C, Sailer C, Zisser G, Marques-Carvalho MJ, Pellegrino S, Wawiórka L, Freund SM, Wagstaff JL, Andreeva A, Faille A, Chen E, Stengel F, Bergler H, Warren AJ.

Elife. 2019 May 22;8. pii: e44904. doi: 10.7554/eLife.44904.

7.

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.

Gersch M, Wagstaff JL, Toms AV, Graves B, Freund SMV, Komander D.

Mol Cell. 2019 May 2;74(3):436-451.e7. doi: 10.1016/j.molcel.2019.02.030. Epub 2019 Mar 26.

8.

Is there consensus regarding surgical treatment of bone sarcomas?

Baad-Hansen T, Freund SS, Bech BH, Keller J.

World J Orthop. 2018 Sep 18;9(9):173-179. doi: 10.5312/wjo.v9.i9.173. eCollection 2018 Sep 18.

9.

Disease-Associated Mutations in CEP120 Destabilize the Protein and Impair Ciliogenesis.

Joseph N, Al-Jassar C, Johnson CM, Andreeva A, Barnabas DD, Freund SMV, Gergely F, van Breugel M.

Cell Rep. 2018 May 29;23(9):2805-2818. doi: 10.1016/j.celrep.2018.04.100.

10.

Direct binding of CEP85 to STIL ensures robust PLK4 activation and efficient centriole assembly.

Liu Y, Gupta GD, Barnabas DD, Agircan FG, Mehmood S, Wu D, Coyaud E, Johnson CM, McLaughlin SH, Andreeva A, Freund SMV, Robinson CV, Cheung SWT, Raught B, Pelletier L, van Breugel M.

Nat Commun. 2018 Apr 30;9(1):1731. doi: 10.1038/s41467-018-04122-x.

11.

A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding.

Stowell JAW, Wagstaff JL, Hill CH, Yu M, McLaughlin SH, Freund SMV, Passmore LA.

J Biol Chem. 2018 Jun 15;293(24):9210-9222. doi: 10.1074/jbc.RA118.002291. Epub 2018 Apr 25.

12.

Anchoring of a dye precursor on NiO(001) studied by non-contact atomic force microscopy.

Freund S, Hinaut A, Marinakis N, Constable EC, Meyer E, Housecroft CE, Glatzel T.

Beilstein J Nanotechnol. 2018 Jan 23;9:242-249. doi: 10.3762/bjnano.9.26. eCollection 2018.

13.

Structure of PINK1 in complex with its substrate ubiquitin.

Schubert AF, Gladkova C, Pardon E, Wagstaff JL, Freund SMV, Steyaert J, Maslen SL, Komander D.

Nature. 2017 Dec 7;552(7683):51-56. doi: 10.1038/nature24645. Epub 2017 Oct 30.

14.

An invisible ubiquitin conformation is required for efficient phosphorylation by PINK1.

Gladkova C, Schubert AF, Wagstaff JL, Pruneda JN, Freund SM, Komander D.

EMBO J. 2017 Dec 15;36(24):3555-3572. doi: 10.15252/embj.201797876. Epub 2017 Nov 13.

15.

Synthetic cannabinoids: A review of the clinical implications of a new drug of choice.

Freund SA, Banning AS.

JAAPA. 2017 Nov;30(11):1-4. doi: 10.1097/01.JAA.0000525914.28344.e2. Review.

PMID:
29064946
16.

Nanostructuring of an alkali halide surface by low temperature plasma exposure.

Hinaut A, Eren B, Steiner R, Freund S, Jöhr R, Glatzel T, Marot L, Meyer E, Kawai S.

Phys Chem Chem Phys. 2017 Jun 21;19(24):16251-16256. doi: 10.1039/c7cp02592k.

PMID:
28608893
17.

Laser beam melting 3D printing of Ti6Al4V based porous structured dental implants: fabrication, biocompatibility analysis and photoelastic study.

Yang F, Chen C, Zhou Q, Gong Y, Li R, Li C, Klämpfl F, Freund S, Wu X, Sun Y, Li X, Schmidt M, Ma D, Yu Y.

Sci Rep. 2017 Mar 28;7:45360. doi: 10.1038/srep45360.

18.

Self-correcting mismatches during high-fidelity DNA replication.

Fernandez-Leiro R, Conrad J, Yang JC, Freund SM, Scheres SH, Lamers MH.

Nat Struct Mol Biol. 2017 Feb;24(2):140-143. doi: 10.1038/nsmb.3348. Epub 2017 Jan 9.

19.

The topology, structure and PE interaction of LITAF underpin a Charcot-Marie-Tooth disease type 1C.

Ho AK, Wagstaff JL, Manna PT, Wartosch L, Qamar S, Garman EF, Freund SM, Roberts RC.

BMC Biol. 2016 Dec 7;14(1):109.

20.

The Emotion Word Fluency Test (EWFT): Initial psychometric, validation, and physiological evidence in young adults.

Abeare CA, Freund S, Kaploun K, McAuley T, Dumitrescu C.

J Clin Exp Neuropsychol. 2017 Oct;39(8):738-752. doi: 10.1080/13803395.2016.1259396. Epub 2016 Nov 28.

PMID:
27892775
21.

Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.

Mevissen TET, Kulathu Y, Mulder MPC, Geurink PP, Maslen SL, Gersch M, Elliott PR, Burke JE, van Tol BDM, Akutsu M, Oualid FE, Kawasaki M, Freund SMV, Ovaa H, Komander D.

Nature. 2016 Oct 20;538(7625):402-405. doi: 10.1038/nature19836. Epub 2016 Oct 12.

22.

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

Elliott PR, Leske D, Hrdinka M, Bagola K, Fiil BK, McLaughlin SH, Wagstaff J, Volkmar N, Christianson JC, Kessler BM, Freund SM, Komander D, Gyrd-Hansen M.

Mol Cell. 2016 Sep 15;63(6):990-1005. doi: 10.1016/j.molcel.2016.08.001. Epub 2016 Aug 30.

23.

High-resolution NMR structures of the domains of Saccharomyces cerevisiae Tho1.

Jacobsen JO, Allen MD, Freund SM, Bycroft M.

Acta Crystallogr F Struct Biol Commun. 2016 Jun;72(Pt 6):500-6. doi: 10.1107/S2053230X16007597. Epub 2016 May 23.

24.

Morphology Change of C60 Islands on Organic Crystals Observed by Atomic Force Microscopy.

Freund S, Hinaut A, Pawlak R, Liu SX, Decurtins S, Meyer E, Glatzel T.

ACS Nano. 2016 Jun 28;10(6):5782-8. doi: 10.1021/acsnano.5b07971. Epub 2016 Jun 3.

PMID:
27219352
25.

The SWI/SNF Subunit INI1 Contains an N-Terminal Winged Helix DNA Binding Domain that Is a Target for Mutations in Schwannomatosis.

Allen MD, Freund SM, Zinzalla G, Bycroft M.

Structure. 2015 Jul 7;23(7):1344-9. doi: 10.1016/j.str.2015.04.021. Epub 2015 Jun 11.

26.

Deconvoluting Protein (Un)folding Structural Ensembles Using X-Ray Scattering, Nuclear Magnetic Resonance Spectroscopy and Molecular Dynamics Simulation.

Nasedkin A, Marcellini M, Religa TL, Freund SM, Menzel A, Fersht AR, Jemth P, van der Spoel D, Davidsson J.

PLoS One. 2015 May 6;10(5):e0125662. doi: 10.1371/journal.pone.0125662. eCollection 2015.

27.

Solution structure of a soluble fragment derived from a membrane protein by shotgun proteolysis.

Allen MD, Christie M, Jones P, Porebski BT, Roome B, Freund SM, Buckle AM, Bycroft M, Christ D.

Protein Eng Des Sel. 2015 Oct;28(10):445-50. doi: 10.1093/protein/gzv021. Epub 2015 Apr 15.

28.

Assembly and specific recognition of k29- and k33-linked polyubiquitin.

Michel MA, Elliott PR, Swatek KN, Simicek M, Pruneda JN, Wagstaff JL, Freund SM, Komander D.

Mol Cell. 2015 Apr 2;58(1):95-109. doi: 10.1016/j.molcel.2015.01.042. Epub 2015 Mar 5.

29.

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.

Wauer T, Swatek KN, Wagstaff JL, Gladkova C, Pruneda JN, Michel MA, Gersch M, Johnson CM, Freund SM, Komander D.

EMBO J. 2015 Feb 3;34(3):307-25. doi: 10.15252/embj.201489847. Epub 2014 Dec 19.

30.

Molecular basis and regulation of OTULIN-LUBAC interaction.

Elliott PR, Nielsen SV, Marco-Casanova P, Fiil BK, Keusekotten K, Mailand N, Freund SM, Gyrd-Hansen M, Komander D.

Mol Cell. 2014 May 8;54(3):335-48. doi: 10.1016/j.molcel.2014.03.018. Epub 2014 Apr 10.

31.

GpIbα interacts exclusively with exosite II of thrombin.

Lechtenberg BC, Freund SM, Huntington JA.

J Mol Biol. 2014 Feb 20;426(4):881-93. doi: 10.1016/j.jmb.2013.11.027. Epub 2013 Dec 5.

32.

Identification of growth phases and influencing factors in cultivations with AGE1.HN cells using set-based methods.

Borchers S, Freund S, Rath A, Streif S, Reichl U, Findeisen R.

PLoS One. 2013 Aug 2;8(8):e68124. doi: 10.1371/journal.pone.0068124. Print 2013.

33.

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358.

Bichel K, Price AJ, Schaller T, Towers GJ, Freund SM, James LC.

Retrovirology. 2013 Jul 31;10:81. doi: 10.1186/1742-4690-10-81.

34.

The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry.

Jürgens MC, Vörös J, Rautureau GJ, Shepherd DA, Pye VE, Muldoon J, Johnson CM, Ashcroft AE, Freund SM, Ferguson N.

Nat Chem Biol. 2013 Sep;9(9):540-7. doi: 10.1038/nchembio.1294. Epub 2013 Jul 14.

PMID:
23851574
35.

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis.

Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D.

Cell. 2013 Jul 3;154(1):169-84. doi: 10.1016/j.cell.2013.05.046.

36.

Thermodynamic origins of protein folding, allostery, and capsid formation in the human hepatitis B virus core protein.

Alexander CG, Jürgens MC, Shepherd DA, Freund SM, Ashcroft AE, Ferguson N.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):E2782-91. doi: 10.1073/pnas.1308846110. Epub 2013 Jul 3.

37.

Fluorescent proteins as biosensors by quenching resonance energy transfer from endogenous tryptophan: detection of nitroaromatic explosives.

Gingras A, Sarette J, Shawler E, Lee T, Freund S, Holwitt E, Hicks BW.

Biosens Bioelectron. 2013 Oct 15;48:251-7. doi: 10.1016/j.bios.2013.03.076. Epub 2013 Apr 23.

PMID:
23708748
38.

Assembly, analysis and architecture of atypical ubiquitin chains.

Hospenthal MK, Freund SM, Komander D.

Nat Struct Mol Biol. 2013 May;20(5):555-65. doi: 10.1038/nsmb.2547. Epub 2013 Apr 7.

39.

The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import.

Veillette M, Bichel K, Pawlica P, Freund SM, Plourde MB, Pham QT, Reyes-Moreno C, James LC, Berthoux L.

Retrovirology. 2013 Feb 28;10:25. doi: 10.1186/1742-4690-10-25.

40.

An essential role for the ATG8 ortholog LC3C in antibacterial autophagy.

von Muhlinen N, Akutsu M, Ravenhill BJ, Foeglein Á, Bloor S, Rutherford TJ, Freund SM, Komander D, Randow F.

Autophagy. 2013 May;9(5):784-6. doi: 10.4161/auto.23698. Epub 2013 Feb 22.

41.

Molecular basis for modulation of the p53 target selectivity by KLF4.

Brandt T, Townsley FM, Teufel DP, Freund SM, Veprintsev DB.

PLoS One. 2012;7(10):e48252. doi: 10.1371/journal.pone.0048252. Epub 2012 Oct 30.

42.

LC3C, bound selectively by a noncanonical LIR motif in NDP52, is required for antibacterial autophagy.

von Muhlinen N, Akutsu M, Ravenhill BJ, Foeglein Á, Bloor S, Rutherford TJ, Freund SM, Komander D, Randow F.

Mol Cell. 2012 Nov 9;48(3):329-42. doi: 10.1016/j.molcel.2012.08.024. Epub 2012 Sep 27.

43.

Domain-domain interactions in full-length p53 and a specific DNA complex probed by methyl NMR spectroscopy.

Bista M, Freund SM, Fersht AR.

Proc Natl Acad Sci U S A. 2012 Sep 25;109(39):15752-6. Epub 2012 Sep 12.

44.

An ensemble view of thrombin allostery.

Lechtenberg BC, Freund SM, Huntington JA.

Biol Chem. 2012 Sep;393(9):889-98. doi: 10.1515/hsz-2012-0178. Review.

PMID:
22944689
45.

FtsA forms actin-like protofilaments.

Szwedziak P, Wang Q, Freund SM, Löwe J.

EMBO J. 2012 May 16;31(10):2249-60. doi: 10.1038/emboj.2012.76. Epub 2012 Mar 30.

46.

Diverse HIV viruses are targeted by a conformationally dynamic antiviral.

Caines ME, Bichel K, Price AJ, McEwan WA, Towers GJ, Willett BJ, Freund SM, James LC.

Nat Struct Mol Biol. 2012 Mar 11;19(4):411-6. doi: 10.1038/nsmb.2253.

47.

The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.

Agromayor M, Soler N, Caballe A, Kueck T, Freund SM, Allen MD, Bycroft M, Perisic O, Ye Y, McDonald B, Scheel H, Hofmann K, Neil SJ, Martin-Serrano J, Williams RL.

Structure. 2012 Mar 7;20(3):414-28. doi: 10.1016/j.str.2011.12.013.

48.

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid.

de la Roche M, Rutherford TJ, Gupta D, Veprintsev DB, Saxty B, Freund SM, Bienz M.

Nat Commun. 2012 Feb 21;3:680. doi: 10.1038/ncomms1680.

49.

Structural basis of p63α SAM domain mutants involved in AEC syndrome.

Sathyamurthy A, Freund SM, Johnson CM, Allen MD, Bycroft M.

FEBS J. 2011 Aug;278(15):2680-8. doi: 10.1111/j.1742-4658.2011.08194.x. Epub 2011 Jun 20.

50.

Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome.

Finch AJ, Hilcenko C, Basse N, Drynan LF, Goyenechea B, Menne TF, González Fernández A, Simpson P, D'Santos CS, Arends MJ, Donadieu J, Bellanné-Chantelot C, Costanzo M, Boone C, McKenzie AN, Freund SM, Warren AJ.

Genes Dev. 2011 May 1;25(9):917-29. doi: 10.1101/gad.623011.

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