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Items: 29

1.

Induced pluripotent stem cells throughout the animal kingdom: Availability and applications.

Pessôa LVF, Bressan FF, Freude KK.

World J Stem Cells. 2019 Aug 26;11(8):491-505. doi: 10.4252/wjsc.v11.i8.491. Review.

2.

Generation of transgene-free porcine intermediate type induced pluripotent stem cells.

Li D, Secher J, Hyttel P, Ivask M, Kolko M, Hall VJ, Freude KK.

Cell Cycle. 2018;17(23):2547-2563. doi: 10.1080/15384101.2018.1548790. Epub 2018 Dec 3.

PMID:
30457474
3.

WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.

Pan X, Xiong K, Anthon C, Hyttel P, Freude KK, Jensen LJ, Gorodkin J.

Genes (Basel). 2018 Nov 6;9(11). pii: E536. doi: 10.3390/genes9110536.

4.

Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges.

Poon A, Zhang Y, Chandrasekaran A, Phanthong P, Schmid B, Nielsen TT, Freude KK.

N Biotechnol. 2017 Oct 25;39(Pt B):190-198. doi: 10.1016/j.nbt.2017.05.009. Epub 2017 Jun 2. Review.

PMID:
28579476
5.

RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts.

Xiong K, Zhou Y, Blichfeld KA, Hyttel P, Bolund L, Freude KK, Luo Y.

Cell Reprogram. 2017 Jun;19(3):189-198. doi: 10.1089/cell.2017.0006.

PMID:
28557624
6.

Identification of SSEA-1 expressing enhanced reprogramming (SEER) cells in porcine embryonic fibroblasts.

Li D, Secher JO, Juhl M, Mashayekhi K, Nielsen TT, Holst B, Hyttel P, Freude KK, Hall VJ.

Cell Cycle. 2017 Jun 3;16(11):1070-1084. doi: 10.1080/15384101.2017.1315490. Epub 2017 Apr 20.

7.

Characterization of energy and neurotransmitter metabolism in cortical glutamatergic neurons derived from human induced pluripotent stem cells: A novel approach to study metabolism in human neurons.

Aldana BI, Zhang Y, Lihme MF, Bak LK, Nielsen JE, Holst B, Hyttel P, Freude KK, Waagepetersen HS.

Neurochem Int. 2017 Jun;106:48-61. doi: 10.1016/j.neuint.2017.02.010. Epub 2017 Feb 24.

PMID:
28237843
8.

Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B.

Zhang Y, Schmid B, Nikolaisen NK, Rasmussen MA, Aldana BI, Agger M, Calloe K, Stummann TC, Larsen HM, Nielsen TT, Huang J, Xu F, Liu X, Bolund L, Meyer M, Bak LK, Waagepetersen HS, Luo Y, Nielsen JE; FReJA Consortium, Holst B, Clausen C, Hyttel P, Freude KK.

Stem Cell Reports. 2017 Mar 14;8(3):648-658. doi: 10.1016/j.stemcr.2017.01.012. Epub 2017 Feb 16.

9.

Evaluation of porcine stem cell competence for somatic cell nuclear transfer and production of cloned animals.

Secher JO, Liu Y, Petkov S, Luo Y, Li D, Hall VJ, Schmidt M, Callesen H, Bentzon JF, Sørensen CB, Freude KK, Hyttel P.

Anim Reprod Sci. 2017 Mar;178:40-49. doi: 10.1016/j.anireprosci.2017.01.007. Epub 2017 Jan 19.

PMID:
28126267
10.

Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells.

Secher JO, Ceylan A, Mazzoni G, Mashayekhi K, Li T, Muenthaisong S, Nielsen TT, Li D, Li S, Petkov S, Cirera S, Luo Y, Thombs L, Kadarmideen HN, Dinnyes A, Bolund L, Roelen BA, Schmidt M, Callesen H, Hyttel P, Freude KK.

Mol Reprod Dev. 2017 Mar;84(3):229-245. doi: 10.1002/mrd.22771.

11.

Generation of induced pluripotent stem cells (iPSCs) stably expressing CRISPR-based synergistic activation mediator (SAM).

Xiong K, Zhou Y, Hyttel P, Bolund L, Freude KK, Luo Y.

Stem Cell Res. 2016 Nov;17(3):665-669. doi: 10.1016/j.scr.2016.10.011. Epub 2016 Nov 17.

12.

Generation of a gene-corrected isogenic control cell line from an Alzheimer's disease patient iPSC line carrying a A79V mutation in PSEN1.

Pires C, Schmid B, Petræus C, Poon A, Nimsanor N, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Hyttel P, Freude KK.

Stem Cell Res. 2016 Sep;17(2):285-288. doi: 10.1016/j.scr.2016.08.002. Epub 2016 Aug 7.

13.

Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1.

Poon A, Li T, Pires C, Nielsen TT, Nielsen JE, Holst B, Dinnyes A, Hyttel P, Freude KK.

Stem Cell Res. 2016 Nov;17(3):470-473. doi: 10.1016/j.scr.2016.09.016. Epub 2016 Sep 28.

14.

Generation of a gene-corrected isogenic control hiPSC line derived from a familial Alzheimer's disease patient carrying a L150P mutation in presenilin 1.

Poon A, Schmid B, Pires C, Nielsen TT, Hjermind LE, Nielsen JE, Holst B, Hyttel P, Freude KK.

Stem Cell Res. 2016 Nov;17(3):466-469. doi: 10.1016/j.scr.2016.09.018. Epub 2016 Sep 24.

15.

Mitochondrial Spare Respiratory Capacity Is Negatively Correlated with Nuclear Reprogramming Efficiency.

Zhou Y, Al-Saaidi RA, Fernandez-Guerra P, Freude KK, Olsen RK, Jensen UB, Gregersen N, Hyttel P, Bolund L, Aagaard L, Bross P, Luo Y.

Stem Cells Dev. 2017 Feb 1;26(3):166-176. doi: 10.1089/scd.2016.0162. Epub 2016 Nov 28.

PMID:
27784195
16.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific homozygous mutation in CHMP2B.

Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK.

Stem Cell Res. 2016 Jul;17(1):151-153. doi: 10.1016/j.scr.2016.06.005. Epub 2016 Jun 16.

17.

Generation of a human induced pluripotent stem cell line via CRISPR-Cas9 mediated integration of a site-specific heterozygous mutation in CHMP2B.

Zhang Y, Schmid B, Nielsen TT, Nielsen JE, Clausen C, Hyttel P, Holst B, Freude KK.

Stem Cell Res. 2016 Jul;17(1):148-150. doi: 10.1016/j.scr.2016.06.004. Epub 2016 Jun 16.

18.

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1.

Li T, Pires C, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Dinnyes A, Holst B, Hyttel P, Freude KK.

Stem Cell Res. 2016 Mar;16(2):334-7. doi: 10.1016/j.scr.2016.01.001. Epub 2016 Jan 14.

19.

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1.

Li T, Pires C, Nielsen TT, Waldemar G, Hjermind LE, Nielsen JE, Dinnyes A, Hyttel P, Freude KK.

Stem Cell Res. 2016 Mar;16(2):229-32. doi: 10.1016/j.scr.2016.01.002. Epub 2016 Jan 14.

20.

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a L150P mutation in PSEN-1.

Tubsuwan A, Pires C, Rasmussen MA, Schmid B, Nielsen JE, Hjermind LE, Hall V, Nielsen TT, Waldemar G, Hyttel P, Clausen C, Kitiyanant N, Freude KK, Holst B.

Stem Cell Res. 2016 Jan;16(1):110-2. doi: 10.1016/j.scr.2015.12.015. Epub 2015 Dec 28.

21.

The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF.

Zhou S, Ochalek A, Szczesna K, Avci HX, Kobolák J, Varga E, Rasmussen M, Holst B, Cirera S, Hyttel P, Freude KK, Dinnyés A.

Differentiation. 2016 Oct - Nov;92(4):183-194. doi: 10.1016/j.diff.2016.06.002. Epub 2016 Jun 16.

PMID:
27321088
22.

Neurosphere Based Differentiation of Human iPSC Improves Astrocyte Differentiation.

Zhou S, Szczesna K, Ochalek A, Kobolák J, Varga E, Nemes C, Chandrasekaran A, Rasmussen M, Cirera S, Hyttel P, Dinnyés A, Freude KK, Avci HX.

Stem Cells Int. 2016;2016:4937689. doi: 10.1155/2016/4937689. Epub 2015 Dec 21.

23.

Initial embryology and pluripotent stem cells in the pig--The quest for establishing the pig as a model for cell therapy.

Secher JO, Callesen H, Freude KK, Hyttel P.

Theriogenology. 2016 Jan 1;85(1):162-71. doi: 10.1016/j.theriogenology.2015.09.017. Epub 2015 Sep 14. Review.

PMID:
26474684
24.

Optimization of three-dimensional imaging on in vitro produced porcine blastocysts and chimeras for stem cell testing: a technology report.

Secher JO, Freude KK, Li R, Callesen H.

Stem Cells Dev. 2015 May 1;24(9):1141-5. doi: 10.1089/scd.2014.0503. Epub 2015 Feb 25.

PMID:
25567670
25.

A Sox9/Fgf feed-forward loop maintains pancreatic organ identity.

Seymour PA, Shih HP, Patel NA, Freude KK, Xie R, Lim CJ, Sander M.

Development. 2012 Sep;139(18):3363-72. doi: 10.1242/dev.078733. Epub 2012 Aug 8.

26.

Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells.

Freude KK, Penjwini M, Davis JL, LaFerla FM, Blurton-Jones M.

J Biol Chem. 2011 Jul 8;286(27):24264-74. doi: 10.1074/jbc.M111.227421. Epub 2011 May 23.

27.

Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

Schaffer AE, Freude KK, Nelson SB, Sander M.

Dev Cell. 2010 Jun 15;18(6):1022-9. doi: 10.1016/j.devcel.2010.05.015.

28.

A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation.

Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M.

Dev Biol. 2008 Nov 1;323(1):19-30. doi: 10.1016/j.ydbio.2008.07.034. Epub 2008 Aug 6.

29.

SOX9 is required for maintenance of the pancreatic progenitor cell pool.

Seymour PA, Freude KK, Tran MN, Mayes EE, Jensen J, Kist R, Scherer G, Sander M.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1865-70. Epub 2007 Jan 31.

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