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Items: 34


Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4+ T lymphocyte activation.

Siegmund K, Thuille N, Posch N, Fresser F, Leitges M, Baier G.

Cell Commun Signal. 2019 May 28;17(1):56. doi: 10.1186/s12964-019-0364-0.


Protein kinase N1 critically regulates cerebellar development and long-term function.

zur Nedden S, Eith R, Schwarzer C, Zanetti L, Seitter H, Fresser F, Koschak A, Cameron AJ, Parker PJ, Baier G, Baier-Bitterlich G.

J Clin Invest. 2018 May 1;128(5):2076-2088. doi: 10.1172/JCI96165. Epub 2018 Apr 16.


Expression, Purification, and Biochemical Characterization of Human Afamin.

Altamirano A, Naschberger A, Fürnrohr BG, Saldova R, Struwe WB, Jennings PM, Millán Martín S, Malic S, Plangger I, Lechner S, Pisano R, Peretti N, Linke B, Aguiar MM, Fresser F, Ritsch A, Lenac Rovis T, Goode C, Rudd PM, Scheffzek K, Rupp B, Dieplinger H.

J Proteome Res. 2018 Mar 2;17(3):1269-1277. doi: 10.1021/acs.jproteome.7b00867. Epub 2018 Feb 20.


Novel Insights into the PKCβ-dependent Regulation of the Oxidoreductase p66Shc.

Haller M, Khalid S, Kremser L, Fresser F, Furlan T, Hermann M, Guenther J, Drasche A, Leitges M, Giorgio M, Baier G, Lindner H, Troppmair J.

J Biol Chem. 2016 Nov 4;291(45):23557-23568. Epub 2016 Sep 13.


Inhibition of CBLB protects from lethal Candida albicans sepsis.

Wirnsberger G, Zwolanek F, Asaoka T, Kozieradzki I, Tortola L, Wimmer RA, Kavirayani A, Fresser F, Baier G, Langdon WY, Ikeda F, Kuchler K, Penninger JM.

Nat Med. 2016 Aug;22(8):915-23. doi: 10.1038/nm.4134. Epub 2016 Jul 18.


cJun N-terminal kinase (JNK) phosphorylation of serine 36 is critical for p66Shc activation.

Khalid S, Drasche A, Thurner M, Hermann M, Ashraf MI, Fresser F, Baier G, Kremser L, Lindner H, Troppmair J.

Sci Rep. 2016 Feb 12;6:20930. doi: 10.1038/srep20930.


Novel protein kinase C θ: coronin 1A complex in T lymphocytes.

Siegmund K, Thuille N, Posch N, Fresser F, Baier G.

Cell Commun Signal. 2015 Mar 31;13:22. doi: 10.1186/s12964-015-0100-3.


Sequence variation within the KIV-2 copy number polymorphism of the human LPA gene in African, Asian, and European populations.

Noureen A, Fresser F, Utermann G, Schmidt K.

PLoS One. 2015 Mar 30;10(3):e0121582. doi: 10.1371/journal.pone.0121582. eCollection 2015.


Phosphorylation of Rab5a protein by protein kinase Cϵ is crucial for T-cell migration.

Ong ST, Freeley M, Skubis-Zegadło J, Fazil MH, Kelleher D, Fresser F, Baier G, Verma NK, Long A.

J Biol Chem. 2014 Jul 11;289(28):19420-34. doi: 10.1074/jbc.M113.545863. Epub 2014 May 28.


PKCθ/β and CYLD are antagonistic partners in the NFκB and NFAT transactivation pathways in primary mouse CD3+ T lymphocytes.

Thuille N, Wachowicz K, Hermann-Kleiter N, Kaminski S, Fresser F, Lutz-Nicoladoni C, Leitges M, Thome M, Massoumi R, Baier G.

PLoS One. 2013;8(1):e53709. doi: 10.1371/journal.pone.0053709. Epub 2013 Jan 15.


Protein kinase C overexpression does not enhance immune-stimulatory surface markers of vaccinia-infected dendritic cells and DC cell lines.

Huemer HP, Geiger M, Posch W, Krumböck N, Fresser F, Wilflingseder D, Uberall F.

Immunol Invest. 2013;42(2):164-77. doi: 10.3109/08820139.2012.750340.


The kinase PKCα selectively upregulates interleukin-17A during Th17 cell immune responses.

Meisel M, Hermann-Kleiter N, Hinterleitner R, Gruber T, Wachowicz K, Pfeifhofer-Obermair C, Fresser F, Leitges M, Soldani C, Viola A, Kaminski S, Baier G.

Immunity. 2013 Jan 24;38(1):41-52. doi: 10.1016/j.immuni.2012.09.021. Epub 2013 Jan 3.


Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.

Hermann-Kleiter N, Meisel M, Fresser F, Thuille N, Müller M, Roth L, Katopodis A, Baier G.

J Autoimmun. 2012 Dec;39(4):428-40. doi: 10.1016/j.jaut.2012.07.007. Epub 2012 Aug 24.


Coronin 1A is an essential regulator of the TGFβ receptor/SMAD3 signaling pathway in Th17 CD4(+) T cells.

Kaminski S, Hermann-Kleiter N, Meisel M, Thuille N, Cronin S, Hara H, Fresser F, Penninger JM, Baier G.

J Autoimmun. 2011 Nov;37(3):198-208. doi: 10.1016/j.jaut.2011.05.018. Epub 2011 Jun 22.


"Essentially" pure trisomy 3q27 --> qter: further delineation of the partial trisomy 3q phenotype.

Grossmann V, Müller D, Müller W, Fresser F, Erdel M, Janecke AR, Zschocke J, Utermann G, Kotzot D.

Am J Med Genet A. 2009 Nov;149A(11):2522-6. doi: 10.1002/ajmg.a.33058.


PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation.

Gruber T, Hermann-Kleiter N, Hinterleitner R, Fresser F, Schneider R, Gastl G, Penninger JM, Baier G.

Sci Signal. 2009 Jun 23;2(76):ra30. doi: 10.1126/scisignal.2000046.


PKC-theta selectively controls the adhesion-stimulating molecule Rap1.

Letschka T, Kollmann V, Pfeifhofer-Obermair C, Lutz-Nicoladoni C, Obermair GJ, Fresser F, Leitges M, Hermann-Kleiter N, Kaminski S, Baier G.

Blood. 2008 Dec 1;112(12):4617-27. doi: 10.1182/blood-2007-11-121111. Epub 2008 Sep 16.


The nuclear orphan receptor NR2F6 suppresses lymphocyte activation and T helper 17-dependent autoimmunity.

Hermann-Kleiter N, Gruber T, Lutz-Nicoladoni C, Thuille N, Fresser F, Labi V, Schiefermeier N, Warnecke M, Huber L, Villunger A, Eichele G, Kaminski S, Baier G.

Immunity. 2008 Aug 15;29(2):205-16. doi: 10.1016/j.immuni.2008.06.008.


PKCtheta cooperates with atypical PKCzeta and PKCiota in NF-kappaB transactivation of T lymphocytes.

Gruber T, Fresser F, Jenny M, Uberall F, Leitges M, Baier G.

Mol Immunol. 2008 Jan;45(1):117-26. Epub 2007 Jun 22.


Critical role of novel Thr-219 autophosphorylation for the cellular function of PKCtheta in T lymphocytes.

Thuille N, Heit I, Fresser F, Krumböck N, Bauer B, Leuthaeusser S, Dammeier S, Graham C, Copeland TD, Shaw S, Baier G.

EMBO J. 2005 Nov 16;24(22):3869-80. Epub 2005 Oct 27.


A common nonsense mutation in the repetitive Kringle IV-2 domain of human apolipoprotein(a) results in a truncated protein and low plasma Lp(a).

Parson W, Kraft HG, Niederstätter H, Lingenhel AW, Köchl S, Fresser F, Utermann G.

Hum Mutat. 2004 Dec;24(6):474-80.


AKT1/PKBalpha is recruited to lipid rafts and activated downstream of PKC isotypes in CD3-induced T cell signaling.

Bauer B, Jenny M, Fresser F, Uberall F, Baier G.

FEBS Lett. 2003 Apr 24;541(1-3):155-62.


Direct interaction of the extracellular matrix protein DANCE with apolipoprotein(a) mediated by the kringle IV-type 2 domain.

Kapetanopoulos A, Fresser F, Millonig G, Shaul Y, Baier G, Utermann G.

Mol Genet Genomics. 2002 Jun;267(4):440-6. Epub 2002 May 25.


The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase itch.

Traweger A, Fang D, Liu YC, Stelzhammer W, Krizbai IA, Fresser F, Bauer HC, Bauer H.

J Biol Chem. 2002 Mar 22;277(12):10201-8. Epub 2002 Jan 8.


Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells.

Bauer B, Krumböck N, Fresser F, Hochholdinger F, Spitaler M, Simm A, Uberall F, Schraven B, Baier G.

J Biol Chem. 2001 Aug 24;276(34):31627-34. Epub 2001 Jun 15.


Determination of protein-protein interactions of ICIn by the yeast two-hybrid system.

Schmarda A, Fresser F, Gschwentner M, Fürst J, Ritter M, Lang F, Baier G, Paulmichl M.

Cell Physiol Biochem. 2001;11(1):55-60.


Mutation analysis in glycogen storage disease type 1 non-a.

Janecke AR, Lindner M, Erdel M, Mayatepek E, Möslinger D, Podskarbi T, Fresser F, Stöckler-Ipsiroglu S, Hoffmann GF, Utermann G.

Hum Genet. 2000 Sep;107(3):285-9.


Mapping of a minimal apolipoprotein(a) interaction motif conserved in fibrin(ogen) beta - and gamma -chains.

Klose R, Fresser F, Kochl S, Parson W, Kapetanopoulos A, Fruchart-Najib J, Baier G, Utermann G.

J Biol Chem. 2000 Dec 8;275(49):38206-12.


Physical interaction of ApoE with amyloid precursor protein independent of the amyloid Abeta region in vitro.

Hass S, Fresser F, Köchl S, Beyreuther K, Utermann G, Baier G.

J Biol Chem. 1998 May 29;273(22):13892-7.


Novel interaction of apolipoprotein(a) with beta-2 glycoprotein I mediated by the kringle IV domain.

Köchl S, Fresser F, Lobentanz E, Baier G, Utermann G.

Blood. 1997 Aug 15;90(4):1482-9.


Conventional PKC-alpha, novel PKC-epsilon and PKC-theta, but not atypical PKC-lambda are MARCKS kinases in intact NIH 3T3 fibroblasts.

Uberall F, Giselbrecht S, Hellbert K, Fresser F, Bauer B, Gschwendt M, Grunicke HH, Baier G.

J Biol Chem. 1997 Feb 14;272(7):4072-8.


trans-Activation of the HIV type 1 promoter by 7,8-dihydroneopterin in vitro.

Baier-Bitterlich G, Fuchs D, Zangerle R, Baeuerle PA, Werner ER, Fresser F, Uberall F, Baier G, Wachter H.

AIDS Res Hum Retroviruses. 1997 Jan 20;13(2):173-8.


Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes.

Baier-Bitterlich G, Uberall F, Bauer B, Fresser F, Wachter H, Grunicke H, Utermann G, Altman A, Baier G.

Mol Cell Biol. 1996 Apr;16(4):1842-50.


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