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Items: 1 to 50 of 54

1.

cDC1s: New Orchestrators of Tissue Innate Immunity.

Del Fresno C, Sancho D.

Trends Immunol. 2019 May 24. pii: S1471-4906(19)30104-8. doi: 10.1016/j.it.2019.05.002. [Epub ahead of print]

PMID:
31133464
2.

Brain Gene Expression Pattern of Subjects with Completed Suicide and Comorbid Substance Use Disorder.

Cabrera B, Monroy-Jaramillo N, Fries GR, Mendoza-Morales RC, García-Dolores F, Mendoza-Larios A, Diaz-Otañez C, Walss-Bass C, Glahn DC, Ostrosky-Wegman P, Fresno C, Nicolini H.

Mol Neuropsychiatry. 2019 Mar;5(1):60-73. doi: 10.1159/000493940. Epub 2018 Nov 12.

PMID:
31019919
3.

A Neutrophil Timer Coordinates Immune Defense and Vascular Protection.

Adrover JM, Del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibáñez B, Hidalgo A.

Immunity. 2019 Feb 19;50(2):390-402.e10. doi: 10.1016/j.immuni.2019.01.002. Epub 2019 Jan 29.

PMID:
30709741
4.

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.

Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S.

Immunity. 2018 Dec 18;49(6):1062-1076.e6. doi: 10.1016/j.immuni.2018.09.018. Epub 2018 Nov 13.

5.

Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection.

Saz-Leal P, Del Fresno C, Brandi P, Martínez-Cano S, Dungan OM, Chisholm JD, Kerr WG, Sancho D.

Cell Rep. 2018 Oct 30;25(5):1118-1126. doi: 10.1016/j.celrep.2018.09.092.

6.

DNGR-1 in dendritic cells limits tissue damage by dampening neutrophil recruitment.

Del Fresno C, Saz-Leal P, Enamorado M, Wculek SK, Martínez-Cano S, Blanco-Menéndez N, Schulz O, Gallizioli M, Miró-Mur F, Cano E, Planas A, Sancho D.

Science. 2018 Oct 19;362(6412):351-356. doi: 10.1126/science.aan8423.

PMID:
30337411
7.

Flexible Signaling of Myeloid C-Type Lectin Receptors in Immunity and Inflammation.

Del Fresno C, Iborra S, Saz-Leal P, Martínez-López M, Sancho D.

Front Immunol. 2018 Apr 26;9:804. doi: 10.3389/fimmu.2018.00804. eCollection 2018. Review.

8.

Dectin-1/2-induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses.

Kaisar MMM, Ritter M, Del Fresno C, Jónasdóttir HS, van der Ham AJ, Pelgrom LR, Schramm G, Layland LE, Sancho D, Prazeres da Costa C, Giera M, Yazdanbakhsh M, Everts B.

PLoS Biol. 2018 Apr 18;16(4):e2005504. doi: 10.1371/journal.pbio.2005504. eCollection 2018 Apr.

9.

Myeloid cell deficiency of p38γ/p38δ protects against candidiasis and regulates antifungal immunity.

Alsina-Beauchamp D, Escós A, Fajardo P, González-Romero D, Díaz-Mora E, Risco A, Martín-Serrano MA, Del Fresno C, Dominguez-Andrés J, Aparicio N, Zur R, Shpiro N, Brown GD, Ardavín C, Netea MG, Alemany S, Sanz-Ezquerro JJ, Cuenda A.

EMBO Mol Med. 2018 May;10(5). pii: e8485. doi: 10.15252/emmm.201708485.

10.

Public insurance program impact on catastrophic health expenditure on acute myocardial infarction.

Martínez-García M, Vargas-Barrón J, Bañuelos-Téllez F, González-Pacheco H, Fresno C, Hernández-Lemus E, Martínez-Ríos MA, Vallejo M.

Public Health. 2018 May;158:47-54. doi: 10.1016/j.puhe.2018.01.025. Epub 2018 Mar 14.

PMID:
29547759
11.

Effect of different mini-volume colloid centrifugation configurations on flow cytometrically sorted sperm recovery efficiency and quality using a computer-assisted semen analyzer.

Ferré LB, Chitwood JL, Fresno C, Ortega HH, Kjelland ME, Ross PJ.

Reprod Domest Anim. 2018 Feb;53(1):26-33. doi: 10.1111/rda.13048. Epub 2017 Sep 11.

PMID:
28891229
12.

Tissue alkalosis in cold-ischemia time.

Denninghoff V, Olivieri EHR, Fresno C, Uceda A, Mota L, Suenaga AP, Carraro DM, Martins VR, Avagnina A, Soares FA, Campos AHJFM.

Sci Rep. 2017 Sep 7;7(1):10867. doi: 10.1038/s41598-017-11284-z.

13.

RNA-Seq based genome-wide analysis reveals loss of inter-chromosomal regulation in breast cancer.

Espinal-Enríquez J, Fresno C, Anda-Jáuregui G, Hernández-Lemus E.

Sci Rep. 2017 May 11;7(1):1760. doi: 10.1038/s41598-017-01314-1.

14.

Neutrophils acROSs the Enemy Lines.

Del Fresno C, Hidalgo A.

Immunity. 2017 Mar 21;46(3):335-337. doi: 10.1016/j.immuni.2017.03.003.

15.

TarSeqQC: Quality control on targeted sequencing experiments in R.

Merino GA, Murua YA, Fresno C, Sendoya JM, Golubicki M, Iseas S, Coraglio M, Podhajcer OL, Llera AS, Fernández EA.

Hum Mutat. 2017 May;38(5):494-502. doi: 10.1002/humu.23204. Epub 2017 Mar 21.

PMID:
28236343
16.

A novel non-parametric method for uncertainty evaluation of correlation-based molecular signatures: its application on PAM50 algorithm.

Fresno C, González GA, Merino GA, Flesia AG, Podhajcer OL, Llera AS, Fernández EA.

Bioinformatics. 2017 Mar 1;33(5):693-700. doi: 10.1093/bioinformatics/btw704.

PMID:
28062443
17.

Predictive Outcomes for HER2-enriched Cancer Using Growth and Metastasis Signatures Driven By SPARC.

Güttlein LN, Benedetti LG, Fresno C, Spallanzani RG, Mansilla SF, Rotondaro C, Raffo Iraolagoitia XL, Salvatierra E, Bravo AI, Fernández EA, Gottifredi V, Zwirner NW, Llera AS, Podhajcer OL.

Mol Cancer Res. 2017 Mar;15(3):304-316. doi: 10.1158/1541-7786.MCR-16-0243-T. Epub 2016 Dec 28.

18.

The ROCK Inhibitor Fasudil Prevents Chronic Restraint Stress-Induced Depressive-Like Behaviors and Dendritic Spine Loss in Rat Hippocampus.

García-Rojo G, Fresno C, Vilches N, Díaz-Véliz G, Mora S, Aguayo F, Pacheco A, Parra-Fiedler N, Parra CS, Rojas PS, Tejos M, Aliaga E, Fiedler JL.

Int J Neuropsychopharmacol. 2017 Apr 1;20(4):336-345. doi: 10.1093/ijnp/pyw108.

19.

Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection.

Iborra S, Martínez-López M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Izquierdo HM, Abram CL, Mori D, Campos-Martín Y, Reguera RM, Kemp B, Yamasaki S, Robinson MJ, Soto M, Lowell CA, Sancho D.

Immunity. 2016 Oct 18;45(4):788-801. doi: 10.1016/j.immuni.2016.09.012. Epub 2016 Oct 11.

20.

Optimal Generation of Tissue-Resident but Not Circulating Memory T Cells during Viral Infection Requires Crosspriming by DNGR-1+ Dendritic Cells.

Iborra S, Martínez-López M, Khouili SC, Enamorado M, Cueto FJ, Conde-Garrosa R, Del Fresno C, Sancho D.

Immunity. 2016 Oct 18;45(4):847-860. doi: 10.1016/j.immuni.2016.08.019. Epub 2016 Sep 27.

21.

Improving information retrieval in functional analysis.

Rodriguez JC, González GA, Fresno C, Llera AS, Fernández EA.

Comput Biol Med. 2016 Dec 1;79:10-20. doi: 10.1016/j.compbiomed.2016.09.017. Epub 2016 Sep 24.

PMID:
27723507
22.

IL-8, GRO and MCP-1 produced by hepatocellular carcinoma microenvironment determine the migratory capacity of human bone marrow-derived mesenchymal stromal cells without affecting tumor aggressiveness.

Bayo J, Real A, Fiore EJ, Malvicini M, Sganga L, Bolontrade M, Andriani O, Bizama C, Fresno C, Podhajcer O, Fernandez E, Gidekel M, Mazzolini GD, García MG.

Oncotarget. 2016 Jun 25;8(46):80235-80248. doi: 10.18632/oncotarget.10288. eCollection 2017 Oct 6.

23.

Effect of spermatozoa motility hyperactivation factors and gamete coincubation duration on in vitro bovine embryo development using flow cytometrically sorted spermatozoa.

Ferré LB, Bogliotti Y, Chitwood JL, Fresno C, Ortega HH, Kjelland ME, Ross PJ.

Reprod Fertil Dev. 2017 Apr;29(4):805-814. doi: 10.1071/RD15289.

PMID:
26907580
24.

SHIP-1 Couples to the Dectin-1 hemITAM and Selectively Modulates Reactive Oxygen Species Production in Dendritic Cells in Response to Candida albicans.

Blanco-Menéndez N, Del Fresno C, Fernandes S, Calvo E, Conde-Garrosa R, Kerr WG, Sancho D.

J Immunol. 2015 Nov 1;195(9):4466-4478. doi: 10.4049/jimmunol.1402874. Epub 2015 Sep 28.

25.

Salvadora persica agro-ecological suitability for oil production in Argentine dryland salinity.

Falasca S, Pitta-Alvarez S, del Fresno CM.

Sci Total Environ. 2015 Dec 15;538:844-54. doi: 10.1016/j.scitotenv.2015.08.082. Epub 2015 Sep 28.

PMID:
26348151
26.

Comparison of different fertilisation media for an in vitro maturation?fertilisation?culture system using flow-cytometrically sorted X chromosome-bearing spermatozoa for bovine embryo production.

Ferré LB, Bogliotti Y, Chitwood JL, Fresno C, Ortega HH, Kjelland ME, Ross PJ.

Reprod Fertil Dev. 2015 May 13. doi: 10.1071/RD15019. [Epub ahead of print]

PMID:
25966894
27.

Contrasting gene expression patterns induced by levodopa and pramipexole treatments in the rat model of Parkinson's disease.

Taravini IR, Larramendy C, Gomez G, Saborido MD, Spaans F, Fresno C, González GA, Fernández E, Murer MG, Gershanik OS.

Neuropharmacology. 2016 Feb;101:576-89. doi: 10.1016/j.neuropharm.2015.04.018. Epub 2015 May 9.

PMID:
25963416
28.

NFκB2/p100 is a key factor for endotoxin tolerance in human monocytes: a demonstration using primary human monocytes from patients with sepsis.

Cubillos-Zapata C, Hernández-Jiménez E, Toledano V, Esteban-Burgos L, Fernández-Ruíz I, Gómez-Piña V, Del Fresno C, Siliceo M, Prieto-Chinchiña P, Pérez de Diego R, Boscá L, Fresno M, Arnalich F, López-Collazo E.

J Immunol. 2014 Oct 15;193(8):4195-202. doi: 10.4049/jimmunol.1400721. Epub 2014 Sep 15.

29.

Pathophysiology of endotoxin tolerance: mechanisms and clinical consequences.

López-Collazo E, del Fresno C.

Crit Care. 2013 Nov 14;17(6):242. doi: 10.1186/cc13110. Review.

30.

IL-4 blocks TH1-polarizing/inflammatory cytokine gene expression during monocyte-derived dendritic cell differentiation through histone hypoacetylation.

López-Bravo M, Minguito de la Escalera M, Domínguez PM, González-Cintado L, del Fresno C, Martín P, Martínez del Hoyo G, Ardavín C.

J Allergy Clin Immunol. 2013 Dec;132(6):1409-19. doi: 10.1016/j.jaci.2013.08.039. Epub 2013 Oct 17.

PMID:
24139608
31.

Molecular pathology of acute kidney injury in a choline-deficient model and fish oil protective effect.

Denninghoff V, Ossani G, Uceda A, Rugnone M, Fernández E, Fresno C, González G, Díaz ML, Avagnina A, Elsner B, Monserrat A.

Eur J Nutr. 2014 Apr;53(3):897-906. doi: 10.1007/s00394-013-0593-8. Epub 2013 Oct 16.

PMID:
24129499
32.

RDAVIDWebService: a versatile R interface to DAVID.

Fresno C, Fernández EA.

Bioinformatics. 2013 Nov 1;29(21):2810-1. doi: 10.1093/bioinformatics/btt487. Epub 2013 Aug 19.

PMID:
23958726
33.

Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

del Fresno C, Soulat D, Roth S, Blazek K, Udalova I, Sancho D, Ruland J, Ardavín C.

Immunity. 2013 Jun 27;38(6):1176-86. doi: 10.1016/j.immuni.2013.05.010. Epub 2013 Jun 13.

34.

The glycan structure in recombinant human FSH affects endocrine activity and global gene expression in human granulosa cells.

Loreti N, Fresno C, Barrera D, Andreone L, Albarran SL, Fernandez EA, Larrea F, Campo S.

Mol Cell Endocrinol. 2013 Feb 5;366(1):68-80. doi: 10.1016/j.mce.2012.11.021. Epub 2012 Dec 20.

PMID:
23261981
35.

p38γ and p38δ kinases regulate the Toll-like receptor 4 (TLR4)-induced cytokine production by controlling ERK1/2 protein kinase pathway activation.

Risco A, del Fresno C, Mambol A, Alsina-Beauchamp D, MacKenzie KF, Yang HT, Barber DF, Morcelle C, Arthur JS, Ley SC, Ardavin C, Cuenda A.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11200-5. doi: 10.1073/pnas.1207290109. Epub 2012 Jun 25.

36.

Impaired antigen presentation and potent phagocytic activity identifying tumor-tolerant human monocytes.

Soares-Schanoski A, Jurado T, Córdoba R, Siliceo M, Fresno CD, Gómez-Piña V, Toledano V, Vallejo-Cremades MT, Alfonso-Iñiguez S, Carballo-Palos A, Fernández-Ruiz I, Cubillas-Zapata C, Biswas SK, Arnalich F, García-Río F, López-Collazo E.

Biochem Biophys Res Commun. 2012 Jun 29;423(2):331-7. doi: 10.1016/j.bbrc.2012.05.124. Epub 2012 May 31.

PMID:
22659741
37.

Monocytes as effector cells: activated Ly-6C(high) mouse monocytes migrate to the lymph nodes through the lymph and cross-present antigens to CD8+ T cells.

Leirião P, del Fresno C, Ardavín C.

Eur J Immunol. 2012 Aug;42(8):2042-51. doi: 10.1002/eji.201142166. Epub 2012 Jul 9.

38.

Role of MMPs in orchestrating inflammatory response in human monocytes via a TREM-1-PI3K-NF-κB pathway.

Gómez-Piña V, Martínez E, Fernández-Ruíz I, Del Fresno C, Soares-Schanoski A, Jurado T, Siliceo M, Toledano V, Fernández-Palomares R, García-Rio F, Arnalich F, Biswas SK, López-Collazo E.

J Leukoc Biol. 2012 Jun;91(6):933-45. doi: 10.1189/jlb.0711340. Epub 2012 Mar 29.

PMID:
22459945
39.

The multi-reference contrast method: facilitating set enrichment analysis.

Fresno C, Llera AS, Girotti MR, Valacco MP, López JA, Podhajcer OL, Balzarini MG, Prada F, Fernández EA.

Comput Biol Med. 2012 Feb;42(2):188-94. doi: 10.1016/j.compbiomed.2011.11.007. Epub 2012 Jan 9.

PMID:
22226646
40.

Translocated LPS might cause endotoxin tolerance in circulating monocytes of cystic fibrosis patients.

del Campo R, Martínez E, del Fresno C, Alenda R, Gómez-Piña V, Fernández-Ruíz I, Siliceo M, Jurado T, Toledano V, Arnalich F, García-Río F, López-Collazo E.

PLoS One. 2011;6(12):e29577. doi: 10.1371/journal.pone.0029577. Epub 2011 Dec 28.

41.

Diagnosis and screening for cytomegalovirus infection in pregnant women in Cuba as prognostic markers of congenital infection in newborns: 2007-2008.

Kourí V, Correa CB, Verdasquera D, Martínez PA, Alvarez A, Alemán Y, Pérez L, Golpe MA, Someilán T, Chong Y, Fresno C, Navarro MA, Pérez E, Moro I, Sanchez R, Llanusa C, Melin P.

Pediatr Infect Dis J. 2010 Dec;29(12):1105-10. doi: 10.1097/INF.0b013e3181eb7388.

PMID:
20622711
42.

Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients.

del Fresno C, García-Rio F, Gómez-Piña V, Soares-Schanoski A, Fernández-Ruíz I, Jurado T, Kajiji T, Shu C, Marín E, Gutierrez del Arroyo A, Prados C, Arnalich F, Fuentes-Prior P, Biswas SK, López-Collazo E.

J Immunol. 2009 May 15;182(10):6494-507. doi: 10.4049/jimmunol.0803350. Erratum in: J Immunol. 2009 Aug 1;183(3):2194. Biswas, Subrha K [corrected to Biswas, Subhra K].

43.

Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism.

del Fresno C, Gómez-Piña V, Lores V, Soares-Schanoski A, Fernández-Ruiz I, Rojo B, Alvarez-Sala R, Caballero-Garrido E, García F, Veliz T, Arnalich F, Fuentes-Prior P, García-Río F, López-Collazo E.

PLoS One. 2008 Jul 16;3(7):e2667. doi: 10.1371/journal.pone.0002667.

44.

Position-dependent expression of GADD45alpha in rat brain tumours.

Brú A, del Fresno C, Soares-Schanoski A, Albertos S, Brú I, Porres A, Rollán-Landeras E, Dopazo A, Casero D, Gómez-Piña V, García L, Arnalich F, Alvarez R, Rodríguez-Rojas A, Fuentes-Prior P, López-Collazo E.

Med Oncol. 2007;24(4):436-44.

PMID:
17917095
45.

Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance.

Biswas SK, Bist P, Dhillon MK, Kajiji T, Del Fresno C, Yamamoto M, Lopez-Collazo E, Akira S, Tergaonkar V.

J Immunol. 2007 Sep 15;179(6):4083-92.

46.

Metalloproteinases shed TREM-1 ectodomain from lipopolysaccharide-stimulated human monocytes.

Gómez-Piña V, Soares-Schanoski A, Rodríguez-Rojas A, Del Fresno C, García F, Vallejo-Cremades MT, Fernández-Ruiz I, Arnalich F, Fuentes-Prior P, López-Collazo E.

J Immunol. 2007 Sep 15;179(6):4065-73.

47.

Inflammatory responses associated with acute coronary syndrome up-regulate IRAK-M and induce endotoxin tolerance in circulating monocytes.

del Fresno C, Soler-Rangel L, Soares-Schanoski A, Gómez-Piña V, González-León MC, Gómez-García L, Mendoza-Barberá E, Rodríguez-Rojas A, García F, Fuentes-Prior P, Arnalich F, López-Collazo E.

J Endotoxin Res. 2007;13(1):39-52.

PMID:
17621545
48.

6-Methylprednisolone down-regulates IRAK-M in human and murine osteoclasts and boosts bone-resorbing activity: a putative mechanism for corticoid-induced osteoporosis.

Soares-Schanoski A, Gómez-Piña V, del Fresno C, Rodríguez-Rojas A, García F, Glaría A, Sánchez M, Vallejo-Cremades MT, Baos R, Fuentes-Prior P, Arnalich F, López-Collazo E.

J Leukoc Biol. 2007 Sep;82(3):700-9. Epub 2007 Jun 18.

PMID:
17576820
49.

Nitric oxide induces SOCS-1 expression in human monocytes in a TNF-alpha-dependent manner.

González-León MC, Soares-Schanoski A, del Fresno C, Cimadevila A, Goméz-Piña V, Mendoza-Barberá E, García F, Marín E, Arnalich F, Fuentes-Prior P, López-Collazo E.

J Endotoxin Res. 2006;12(5):296-306.

PMID:
17059693
50.

Pathophysiology of interleukin-1 receptor-associated kinase-M: implications in refractory state.

López-Collazo E, Fuentes-Prior P, Arnalich F, del Fresno C.

Curr Opin Infect Dis. 2006 Jun;19(3):237-44. Review.

PMID:
16645484

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