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Nitric oxide in the physiology and quality of fleshy fruits.

Palma JM, Freschi L, Rodríguez-Ruiz M, González-Gordo S, Corpas FJ.

J Exp Bot. 2019 Jul 30. pii: erz350. doi: 10.1093/jxb/erz350. [Epub ahead of print]


Reservoirs of resistance: polymyxin resistance in veterinary-associated companion animal isolates of Pseudomonas aeruginosa.

Scott A, Pottenger S, Timofte D, Moore M, Wright L, Kukavica-Ibrulj I, Jeukens J, Levesque RC, Freschi L, Pinchbeck GL, Schmidt VM, McEwan N, Radford AD, Fothergill JL.

Vet Rec. 2019 Aug 17;185(7):206. doi: 10.1136/vr.105075. Epub 2019 Jun 25.


Gasotransmitters in Action: Nitric Oxide-Ethylene Crosstalk during Plant Growth and Abiotic Stress Responses.

Kolbert Z, Feigl G, Freschi L, Poór P.

Antioxidants (Basel). 2019 Jun 8;8(6). pii: E167. doi: 10.3390/antiox8060167. Review.


Editorial: Fruit Ripening: From Present Knowledge to Future Development.

Palma JM, Corpas FJ, Freschi L, Valpuesta V.

Front Plant Sci. 2019 May 1;10:545. doi: 10.3389/fpls.2019.00545. eCollection 2019. No abstract available.


GWAS for quantitative resistance phenotypes in Mycobacterium tuberculosis reveals resistance genes and regulatory regions.

Farhat MR, Freschi L, Calderon R, Ioerger T, Snyder M, Meehan CJ, de Jong B, Rigouts L, Sloutsky A, Kaur D, Sunyaev S, van Soolingen D, Shendure J, Sacchettini J, Murray M.

Nat Commun. 2019 May 13;10(1):2128. doi: 10.1038/s41467-019-10110-6.


Beyond multidrug resistance: Leveraging rare variants with machine and statistical learning models in Mycobacterium tuberculosis resistance prediction.

Chen ML, Doddi A, Royer J, Freschi L, Schito M, Ezewudo M, Kohane IS, Beam A, Farhat M.

EBioMedicine. 2019 May;43:356-369. doi: 10.1016/j.ebiom.2019.04.016. Epub 2019 Apr 29.


Whole genome sequencing identifies bacterial factors affecting transmission of multidrug-resistant tuberculosis in a high-prevalence setting.

Dixit A, Freschi L, Vargas R, Calderon R, Sacchettini J, Drobniewski F, Galea JT, Contreras C, Yataco R, Zhang Z, Lecca L, Kolokotronis SO, Mathema B, Farhat MR.

Sci Rep. 2019 Apr 3;9(1):5602. doi: 10.1038/s41598-019-41967-8.


The Pseudomonas aeruginosa Population among Cystic Fibrosis Patients in Quebec, Canada: a Disease Hot Spot without Known Epidemic Isolates.

Jeukens J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault JG, Allard C, Barbeau J, Cantin A, Charette SJ, Déziel E, Malouin F, Milot J, Nguyen D, Popa C, Boyle B, Levesque RC.

J Clin Microbiol. 2019 May 24;57(6). pii: e02019-18. doi: 10.1128/JCM.02019-18. Print 2019 Jun. No abstract available.


Major Release of 161 Whole-Genome Sequences from the International Pseudomonas Consortium Database.

Jeukens J, Emond-Rheault JG, Freschi L, Kukavica-Ibrulj I, Levesque RC.

Microbiol Resour Announc. 2019 Mar 28;8(13). pii: e00013-19. doi: 10.1128/MRA.00013-19.


Solanum lycopersicum GOLDEN 2-LIKE 2 transcription factor affects fruit quality in a light- and auxin-dependent manner.

Lupi ACD, Lira BS, Gramegna G, Trench B, Alves FRR, Demarco D, Peres LEP, Purgatto E, Freschi L, Rossi M.

PLoS One. 2019 Feb 12;14(2):e0212224. doi: 10.1371/journal.pone.0212224. eCollection 2019.


The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity.

Freschi L, Vincent AT, Jeukens J, Emond-Rheault JG, Kukavica-Ibrulj I, Dupont MJ, Charette SJ, Boyle B, Levesque RC.

Genome Biol Evol. 2019 Jan 1;11(1):109-120. doi: 10.1093/gbe/evy259.


PHYTOCHROME-INTERACTING FACTOR 3 mediates light-dependent induction of tocopherol biosynthesis during tomato fruit ripening.

Gramegna G, Rosado D, Sánchez Carranza AP, Cruz AB, Simon-Moya M, Llorente B, Rodríguez-Concepcíon M, Freschi L, Rossi M.

Plant Cell Environ. 2019 Apr;42(4):1328-1339. doi: 10.1111/pce.13467. Epub 2018 Nov 25.


Recurrent water deficit causes alterations in the profile of redox proteins in citrus plants.

Neves DM, Santana-Vieira DDS, Dória MS, Freschi L, Ferreira CF, Soares Filho WDS, Costa MGC, Coelho Filho MA, Micheli F, Gesteira ADS.

Plant Physiol Biochem. 2018 Nov;132:497-507. doi: 10.1016/j.plaphy.2018.09.035. Epub 2018 Sep 28.


Light, Ethylene and Auxin Signaling Interaction Regulates Carotenoid Biosynthesis During Tomato Fruit Ripening.

Cruz AB, Bianchetti RE, Alves FRR, Purgatto E, Peres LEP, Rossi M, Freschi L.

Front Plant Sci. 2018 Sep 18;9:1370. doi: 10.3389/fpls.2018.01370. eCollection 2018.


De novo domestication of wild tomato using genome editing.

Zsögön A, Čermák T, Naves ER, Notini MM, Edel KH, Weinl S, Freschi L, Voytas DF, Kudla J, Peres LEP.

Nat Biotechnol. 2018 Oct 1. doi: 10.1038/nbt.4272. [Epub ahead of print]


Fruit-localized phytochromes regulate plastid biogenesis, starch synthesis, and carotenoid metabolism in tomato.

Ernesto Bianchetti R, Silvestre Lira B, Santos Monteiro S, Demarco D, Purgatto E, Rothan C, Rossi M, Freschi L.

J Exp Bot. 2018 Jun 27;69(15):3573-3586. doi: 10.1093/jxb/ery145.


Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools.

Freschi L, Bertelli C, Jeukens J, Moore MP, Kukavica-Ibrulj I, Emond-Rheault JG, Hamel J, Fothergill JL, Tucker NP, McClean S, Klockgether J, de Soyza A, Brinkman FSL, Levesque RC, Winstanley C.

FEMS Microbiol Lett. 2018 Jul 1;365(14). doi: 10.1093/femsle/fny120.


Robot-assisted laparoscopic single-site hysterectomy: our experience and multicentric comparison with single-port laparoscopy.

Cela V, Marrucci E, Angioni S, Freschi L.

Minerva Ginecol. 2018 Oct;70(5):621-628. doi: 10.23736/S0026-4784.18.04197-7. Epub 2018 May 31.


Salmonella enterica Prophage Sequence Profiles Reflect Genome Diversity and Can Be Used for High Discrimination Subtyping.

Mottawea W, Duceppe MO, Dupras AA, Usongo V, Jeukens J, Freschi L, Emond-Rheault JG, Hamel J, Kukavica-Ibrulj I, Boyle B, Gill A, Burnett E, Franz E, Arya G, Weadge JT, Gruenheid S, Wiedmann M, Huang H, Daigle F, Moineau S, Bekal S, Levesque RC, Goodridge LD, Ogunremi D.

Front Microbiol. 2018 May 4;9:836. doi: 10.3389/fmicb.2018.00836. eCollection 2018.


SELF-PRUNING Acts Synergistically with DIAGEOTROPICA to Guide Auxin Responses and Proper Growth Form.

Silva WB, Vicente MH, Robledo JM, Reartes DS, Ferrari RC, Bianchetti R, Araújo WL, Freschi L, Peres LEP, Zsögön A.

Plant Physiol. 2018 Apr;176(4):2904-2916. doi: 10.1104/pp.18.00038. Epub 2018 Mar 2.


Nitro-oxidative metabolism during fruit ripening.

Corpas FJ, Freschi L, Rodríguez-Ruiz M, Mioto PT, González-Gordo S, Palma JM.

J Exp Bot. 2018 Jun 19;69(14):3449-3463. doi: 10.1093/jxb/erx453.


Volatile organic compounds and nitric oxide as responses of a Brazilian tropical species to ozone: the emission profile of young and mature leaves.

Bison JV, Cardoso-Gustavson P, de Moraes RM, da Silva Pedrosa G, Cruz LS, Freschi L, de Souza SR.

Environ Sci Pollut Res Int. 2018 Feb;25(4):3840-3848. doi: 10.1007/s11356-017-0744-1. Epub 2017 Nov 25.


Comparative analysis of mitochondrial genomes of geographic variants of the gypsy moth, Lymantria dispar, reveals a previously undescribed genotypic entity.

Djoumad A, Nisole A, Zahiri R, Freschi L, Picq S, Gundersen-Rindal DE, Sparks ME, Dewar K, Stewart D, Maaroufi H, Levesque RC, Hamelin RC, Cusson M.

Sci Rep. 2017 Oct 27;7(1):14245. doi: 10.1038/s41598-017-14530-6.


Recurrent water deficit causes epigenetic and hormonal changes in citrus plants.

Neves DM, Almeida LADH, Santana-Vieira DDS, Freschi L, Ferreira CF, Soares Filho WDS, Costa MGC, Micheli F, Coelho Filho MA, Gesteira ADS.

Sci Rep. 2017 Oct 20;7(1):13684. doi: 10.1038/s41598-017-14161-x.


Genomic characterisation of environmental Pseudomonas aeruginosa isolated from dental unit waterlines revealed the insertion sequence ISPa11 as a chaotropic element.

Vincent AT, Freschi L, Jeukens J, Kukavica-Ibrulj I, Emond-Rheault JG, Leduc A, Boyle B, Jean-Pierre F, Groleau MC, Déziel E, Barbeau J, Charette SJ, Levesque RC.

FEMS Microbiol Ecol. 2017 Sep 1;93(9). doi: 10.1093/femsec/fix106.


Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes.

Jeukens J, Kukavica-Ibrulj I, Emond-Rheault JG, Freschi L, Levesque RC.

FEMS Microbiol Lett. 2017 Oct 2;364(18). doi: 10.1093/femsle/fnx161.


Differential accumulation of flavonoids and phytohormones resulting from the canopy/rootstock interaction of citrus plants subjected to dehydration/rehydration.

Santos ICD, Almeida AF, Pirovani CP, Costa MGC, Silva MFDGFD, Bellete BS, Freschi L, Soares Filho W, Coelho Filho MA, Gesteira ADS.

Plant Physiol Biochem. 2017 Oct;119:147-158. doi: 10.1016/j.plaphy.2017.08.019. Epub 2017 Aug 25.


Phytochromobilin deficiency impairs sugar metabolism through the regulation of cytokinin and auxin signaling in tomato fruits.

Bianchetti RE, Cruz AB, Oliveira BS, Demarco D, Purgatto E, Peres LEP, Rossi M, Freschi L.

Sci Rep. 2017 Aug 10;7(1):7822. doi: 10.1038/s41598-017-08448-2.


Prophage Integrase Typing Is a Useful Indicator of Genomic Diversity in Salmonella enterica.

Colavecchio A, D'Souza Y, Tompkins E, Jeukens J, Freschi L, Emond-Rheault JG, Kukavica-Ibrulj I, Boyle B, Bekal S, Tamber S, Levesque RC, Goodridge LD.

Front Microbiol. 2017 Jul 10;8:1283. doi: 10.3389/fmicb.2017.01283. eCollection 2017.


Manipulation of a Senescence-Associated Gene Improves Fleshy Fruit Yield.

Lira BS, Gramegna G, Trench BA, Alves FRR, Silva EM, Silva GFF, Thirumalaikumar VP, Lupi ACD, Demarco D, Purgatto E, Nogueira FTS, Balazadeh S, Freschi L, Rossi M.

Plant Physiol. 2017 Sep;175(1):77-91. doi: 10.1104/pp.17.00452. Epub 2017 Jul 14.


A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis.

Emond-Rheault JG, Jeukens J, Freschi L, Kukavica-Ibrulj I, Boyle B, Dupont MJ, Colavecchio A, Barrere V, Cadieux B, Arya G, Bekal S, Berry C, Burnett E, Cavestri C, Chapin TK, Crouse A, Daigle F, Danyluk MD, Delaquis P, Dewar K, Doualla-Bell F, Fliss I, Fong K, Fournier E, Franz E, Garduno R, Gill A, Gruenheid S, Harris L, Huang CB, Huang H, Johnson R, Joly Y, Kerhoas M, Kong N, Lapointe G, Larivière L, Loignon S, Malo D, Moineau S, Mottawea W, Mukhopadhyay K, Nadon C, Nash J, Ngueng Feze I, Ogunremi D, Perets A, Pilar AV, Reimer AR, Robertson J, Rohde J, Sanderson KE, Song L, Stephan R, Tamber S, Thomassin P, Tremblay D, Usongo V, Vincent C, Wang S, Weadge JT, Wiedmann M, Wijnands L, Wilson ED, Wittum T, Yoshida C, Youfsi K, Zhu L, Weimer BC, Goodridge L, Levesque RC.

Front Microbiol. 2017 Jun 2;8:996. doi: 10.3389/fmicb.2017.00996. eCollection 2017.


Genomics of antibiotic-resistance prediction in Pseudomonas aeruginosa.

Jeukens J, Freschi L, Kukavica-Ibrulj I, Emond-Rheault JG, Tucker NP, Levesque RC.

Ann N Y Acad Sci. 2019 Jan;1435(1):5-17. doi: 10.1111/nyas.13358. Epub 2017 Jun 2. Review.


AnCo3, a New Member of the Emerging Family of Phage-Like Plasmids.

Colavecchio A, Jeukens J, Freschi L, Edmond Rheault JG, Kukavica-Ibrulj I, Levesque R, Goodridge L.

Genome Announc. 2017 May 11;5(19). pii: e00110-17. doi: 10.1128/genomeA.00110-17.


Complete Genome Sequences of Two Phage-Like Plasmids Carrying the CTX-M-15 Extended-Spectrum β-Lactamase Gene.

Colavecchio A, Jeukens J, Freschi L, Edmond Rheault JG, Kukavica-Ibrulj I, Levesque RC, LeJeune J, Goodridge L.

Genome Announc. 2017 May 11;5(19). pii: e00102-17. doi: 10.1128/genomeA.00102-17.


A pan-genomic approach to understand the basis of host adaptation in Achromobacter.

Jeukens J, Freschi L, Vincent AT, Emond-Rheault JG, Kukavica-Ibrulj I, Charette SJ, Levesque RC.

Genome Biol Evol. 2017 Apr 5. doi: 10.1093/gbe/evx061. [Epub ahead of print]


Alternative fluorimetric-based method to detect and compare total S-nitrosothiols in plants.

Mioto PT, Rodríguez-Ruiz M, Mot AC, Zuccarelli R, Corpas FJ, Freschi L, Mercier H.

Nitric Oxide. 2017 Aug 1;68:7-13. doi: 10.1016/j.niox.2017.03.001. Epub 2017 Mar 6.


The role of robotics in the management of endometriosis.

Cela V, Obino ME, Sergiampietri C, Simi G, Papini F, Pinelli S, Freschi L, Artini P.

Minerva Ginecol. 2017 Oct;69(5):504-516. doi: 10.23736/S0026-4784.17.04045-X. Epub 2017 Mar 7. Review.


Shedding light on NO homeostasis: Light as a key regulator of glutathione and nitric oxide metabolisms during seedling deetiolation.

Zuccarelli R, Coelho ACP, Peres LEP, Freschi L.

Nitric Oxide. 2017 Aug 1;68:77-90. doi: 10.1016/j.niox.2017.01.006. Epub 2017 Jan 18.


Survival strategies of citrus rootstocks subjected to drought.

Santana-Vieira DD, Freschi L, Almeida LA, Moraes DH, Neves DM, Santos LM, Bertolde FZ, Soares Filho WD, Coelho Filho MA, Gesteira AD.

Sci Rep. 2016 Dec 20;6:38775. doi: 10.1038/srep38775.


Nitric oxide signaling and its crosstalk with other plant growth regulators in plant responses to abiotic stress.

Asgher M, Per TS, Masood A, Fatma M, Freschi L, Corpas FJ, Khan NA.

Environ Sci Pollut Res Int. 2017 Jan;24(3):2273-2285. doi: 10.1007/s11356-016-7947-8. Epub 2016 Nov 3. Review.


Phytochrome Interacting Factors (PIFs) in Solanum lycopersicum: Diversity, Evolutionary History and Expression Profiling during Different Developmental Processes.

Rosado D, Gramegna G, Cruz A, Lira BS, Freschi L, de Setta N, Rossi M.

PLoS One. 2016 Nov 1;11(11):e0165929. doi: 10.1371/journal.pone.0165929. eCollection 2016.


Robotic single site staging in endometrial cancer: A multi-institution study.

Corrado G, Mereu L, Bogliolo S, Cela V, Freschi L, Carlin R, Gardella B, Mancini E, Tateo S, Spinillo A, Vizza E.

Eur J Surg Oncol. 2016 Oct;42(10):1506-11. doi: 10.1016/j.ejso.2016.08.014. Epub 2016 Aug 30.


A Multi-Species TaqMan PCR Assay for the Identification of Asian Gypsy Moths (Lymantria spp.) and Other Invasive Lymantriines of Biosecurity Concern to North America.

Stewart D, Zahiri R, Djoumad A, Freschi L, Lamarche J, Holden D, Cervantes S, Ojeda DI, Potvin A, Nisole A, Béliveau C, Capron A, Kimoto T, Day B, Yueh H, Duff C, Levesque RC, Hamelin RC, Cusson M.

PLoS One. 2016 Aug 11;11(8):e0160878. doi: 10.1371/journal.pone.0160878. eCollection 2016.


A Novel System for Single-Port Laparoscopic Surgery: Preliminary Experience.

Freschi L, Pluchino N, Angioni S, Simi G, Ruggiero M, Cela V.

Gynecol Obstet Invest. 2016;81(5):454-60. doi: 10.1159/000443394. Epub 2016 May 21.


Fertility-enhancing hysteroscopic surgery.

Cela V, Litta P, Franchini M, Sergiampietri C, Simi G, Freschi L, Artini PG, Papini F.

Minerva Ginecol. 2016 Apr;68(2):167-74. Epub 2016 Feb 29. Review.


Pheophytinase Knockdown Impacts Carbon Metabolism and Nutraceutical Content Under Normal Growth Conditions in Tomato.

Lira BS, Rosado D, Almeida J, de Souza AP, Buckeridge MS, Purgatto E, Guyer L, Hörtensteiner S, Freschi L, Rossi M.

Plant Cell Physiol. 2016 Mar;57(3):642-53. doi: 10.1093/pcp/pcw021. Epub 2016 Feb 14.


Nitric Oxide, Ethylene, and Auxin Cross Talk Mediates Greening and Plastid Development in Deetiolating Tomato Seedlings.

Melo NK, Bianchetti RE, Lira BS, Oliveira PM, Zuccarelli R, Dias DL, Demarco D, Peres LE, Rossi M, Freschi L.

Plant Physiol. 2016 Apr;170(4):2278-94. doi: 10.1104/pp.16.00023. Epub 2016 Feb 1.


Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida.

Vincent AT, Trudel MV, Freschi L, Nagar V, Gagné-Thivierge C, Levesque RC, Charette SJ.

BMC Genomics. 2016 Jan 12;17:44. doi: 10.1186/s12864-016-2381-3.


Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection.

Bianconi I, Jeukens J, Freschi L, Alcalá-Franco B, Facchini M, Boyle B, Molinaro A, Kukavica-Ibrulj I, Tümmler B, Levesque RC, Bragonzi A.

BMC Genomics. 2015 Dec 29;16:1105. doi: 10.1186/s12864-015-2276-8.


Innovations in classical hormonal targets for endometriosis.

Pluchino N, Freschi L, Wenger JM, Streuli I.

Expert Rev Clin Pharmacol. 2016;9(2):317-27. doi: 10.1586/17512433.2016.1129895. Epub 2016 Jan 11. Review.


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