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Items: 1 to 50 of 269

1.

Association of Virologic Failure and Nonnucleoside Reverse Transcriptase Inhibitor Resistance Found in Antiretroviral-Naive Children Infected With Human Immunodeficiency Virus and Given Efavirenz-Based Treatment.

Higa N, Pelz A, Birch D, Beck IA, Sils T, Samson P, Bwakura-Dangarembizi M, Bolton-Moore C, Capparelli E, Chadwick E, Frenkel LM.

J Pediatric Infect Dis Soc. 2019 Jun 13. pii: piz038. doi: 10.1093/jpids/piz038. [Epub ahead of print]

PMID:
31194860
2.

Correlates of HIV detection among breastfeeding postpartum Kenyan women eligible under Option B.

Chan M, Muriuki EM, Emery S, Kanthula R, Chohan V, Frenkel LM, Wald A, Chohan B, Overbaugh J, Roxby AC.

PLoS One. 2019 May 31;14(5):e0216252. doi: 10.1371/journal.pone.0216252. eCollection 2019.

3.

Comparisons of Human Immunodeficiency Virus Type 1 Envelope Variants in Blood and Genital Fluids near the Time of Male-to-Female Transmission.

Williams-Wietzikoski CA, Campbell MS, Payant R, Lam A, Zhao H, Huang H, Wald A, Stevens W, Gray G, Farquhar C, Rees H, Celum C, Mullins JI, Lingappa JR, Frenkel LM.

J Virol. 2019 Jun 14;93(13). pii: e01769-18. doi: 10.1128/JVI.01769-18. Print 2019 Jul 1.

PMID:
30996101
4.

Minority and majority pretreatment HIV-1 drug resistance associated with failure of first-line nonnucleoside reverse-transcriptase inhibitor antiretroviral therapy in Kenyan women.

Milne RS, Silverman RA, Beck IA, Mckernan-Mullin J, Deng W, Sibley TR, Dross S, Kiarie JN, Sakr SR, Coombs RW, Chung MH, Frenkel LM.

AIDS. 2019 May 1;33(6):941-951. doi: 10.1097/QAD.0000000000002134.

PMID:
30946148
5.

Phylogenetic Analyses Comparing HIV Sequences from Plasma at Virologic Failure to Cervix Versus Blood Sequences from Antecedent Antiretroviral Therapy Suppression.

Bull ME, McKernan JL, Styrchak S, Kraft K, Hitti J, Cohn SE, Tapia K, Deng W, Holte S, Mullins JI, Coombs RW, Frenkel LM.

AIDS Res Hum Retroviruses. 2019 Jun;35(6):557-566. doi: 10.1089/AID.2018.0211. Epub 2019 Apr 30.

PMID:
30892052
6.

Minority and majority pre-treatment HIV-1 drug resistance associated with failure of 1st-line NNRTI ART in Kenyan women.

Milne RS, Silverman RA, Beck IA, Mckernan-Mullin J, Deng W, Sibley TR, Dross S, Kiarie JN, Sakr SR, Coombs RW, Chung MH, Frenkel LM.

AIDS. 2019 Jan 16. doi: 10.1097/QAD.0000000000002134. [Epub ahead of print]

PMID:
30664004
7.

Pretreatment HIV Drug Resistance and Virologic Outcomes to First-Line Antiretroviral Therapy in Peru.

Soria J, Mugruza R, Levine M, León SR, Arévalo J, Ticona E, Beck IA, Frenkel LM.

AIDS Res Hum Retroviruses. 2019 Feb;35(2):150-154. doi: 10.1089/AID.2018.0239. Epub 2019 Jan 22.

PMID:
30560685
8.

Safety and efficacy at 240 weeks of different raltegravir formulations in children with HIV-1: a phase 1/2 open label, non-randomised, multicentre trial.

Nachman S, Alvero C, Teppler H, Homony B, Rodgers AJ, Graham BL, Fenton T, Frenkel LM, Browning RS, Hazra R, Wiznia AA; IMPAACT 1066 study team.

Lancet HIV. 2018 Dec;5(12):e715-e722. doi: 10.1016/S2352-3018(18)30257-1.

9.

The clinical implications of pretreatment drug resistance -- a moving target.

Shafer RW, Frenkel LM.

Clin Infect Dis. 2018 Oct 15. doi: 10.1093/cid/ciy895. [Epub ahead of print] No abstract available.

PMID:
30321316
10.

Implementation of a point mutation assay for HIV drug resistance testing in Kenya.

Duarte HA, Beck IA, Levine M, Kiptinness C, Kingoo JM, Chohan B, Sakr SR, Chung MH, Frenkel LM.

AIDS. 2018 Oct 23;32(16):2301-2308. doi: 10.1097/QAD.0000000000001934.

PMID:
30005020
11.

Monotypic low-level HIV viremias during antiretroviral therapy are associated with disproportionate production of X4 virions and systemic immune activation.

Bull ME, Mitchell C, Soria J, Styrchak S, Williams-Wietzikoski C, Legard J, McKernan-Mullin J, Kraft K, Onchiri F, Stern J, Holte S, Ryan KJ, Acosta EP, La Rosa A, Coombs RW, Ticona E, Frenkel LM.

AIDS. 2018 Jul 17;32(11):1389-1401. doi: 10.1097/QAD.0000000000001824.

12.

Transmission of HIV-1 drug resistance mutations within partner-pairs: A cross-sectional study of a primary HIV infection cohort.

Stekler JD, Milne R, Payant R, Beck I, Herbeck J, Maust B, Deng W, Tapia K, Holte S, Maenza J, Stevens CE, Mullins JI, Collier AC, Frenkel LM.

PLoS Med. 2018 Mar 27;15(3):e1002537. doi: 10.1371/journal.pmed.1002537. eCollection 2018 Mar.

13.

Pre-exposure prophylaxis for HIV-negative persons with partners living with HIV: uptake, use, and effectiveness in an open-label demonstration project in East Africa.

Heffron R, Ngure K, Odoyo J, Bulya N, Tindimwebwa E, Hong T, Kidoguchi L, Donnell D, Mugo NR, Bukusi EA, Katabira E, Asiimwe S, Morton J, Morrison S, Haugen H, Mujugira A, Haberer JE, Ware NC, Wyatt MA, Marzinke MA, Frenkel LM, Celum C, Baeten JM; Partners Demonstration Project Team.

Gates Open Res. 2017 Nov 6;1:3. doi: 10.12688/gatesopenres.12752.1.

14.

The Underlying Genetics of Drosophila Circadian Behaviors.

Franco DL, Frenkel L, Ceriani MF.

Physiology (Bethesda). 2018 Jan 1;33(1):50-62. doi: 10.1152/physiol.00020.2017. Review.

15.

HIV-1 drug resistance before initiation or re-initiation of first-line antiretroviral therapy in low-income and middle-income countries: a systematic review and meta-regression analysis.

Gupta RK, Gregson J, Parkin N, Haile-Selassie H, Tanuri A, Andrade Forero L, Kaleebu P, Watera C, Aghokeng A, Mutenda N, Dzangare J, Hone S, Hang ZZ, Garcia J, Garcia Z, Marchorro P, Beteta E, Giron A, Hamers R, Inzaule S, Frenkel LM, Chung MH, de Oliveira T, Pillay D, Naidoo K, Kharsany A, Kugathasan R, Cutino T, Hunt G, Avila Rios S, Doherty M, Jordan MR, Bertagnolio S.

Lancet Infect Dis. 2018 Mar;18(3):346-355. doi: 10.1016/S1473-3099(17)30702-8. Epub 2017 Dec 5. Erratum in: Lancet Infect Dis. 2017 Dec 15;:.

16.

Sieve analysis of breakthrough HIV-1 sequences in HVTN 505 identifies vaccine pressure targeting the CD4 binding site of Env-gp120.

deCamp AC, Rolland M, Edlefsen PT, Sanders-Buell E, Hall B, Magaret CA, Fiore-Gartland AJ, Juraska M, Carpp LN, Karuna ST, Bose M, LePore S, Miller S, O'Sullivan A, Poltavee K, Bai H, Dommaraju K, Zhao H, Wong K, Chen L, Ahmed H, Goodman D, Tay MZ, Gottardo R, Koup RA, Bailer R, Mascola JR, Graham BS, Roederer M, O'Connell RJ, Michael NL, Robb ML, Adams E, D'Souza P, Kublin J, Corey L, Geraghty DE, Frahm N, Tomaras GD, McElrath MJ, Frenkel L, Styrchak S, Tovanabutra S, Sobieszczyk ME, Hammer SM, Kim JH, Mullins JI, Gilbert PB.

PLoS One. 2017 Nov 17;12(11):e0185959. doi: 10.1371/journal.pone.0185959. eCollection 2017.

17.

Prevalence of Pre-antiretroviral-Treatment Drug Resistance by Gender, Age, and Other Factors in HIV-Infected Individuals Initiating Therapy in Kenya, 2013-2014.

Silverman RA, Beck IA, Kiptinness C, Levine M, Milne R, McGrath CJ, Bii S, Richardson BA, John-Stewart G, Chohan B, Sakr SR, Kiarie JN, Frenkel LM, Chung MH.

J Infect Dis. 2017 Dec 19;216(12):1569-1578. doi: 10.1093/infdis/jix544.

18.

Current Status of Point-of-Care Testing for Human Immunodeficiency Virus Drug Resistance.

Duarte HA, Panpradist N, Beck IA, Lutz B, Lai J, Kanthula RM, Kantor R, Tripathi A, Saravanan S, MacLeod IJ, Chung MH, Zhang G, Yang C, Frenkel LM.

J Infect Dis. 2017 Dec 1;216(suppl_9):S824-S828. doi: 10.1093/infdis/jix413. Review.

19.

The pathogenesis of microcephaly resulting from congenital infections: why is my baby's head so small?

Frenkel LD, Gomez F, Sabahi F.

Eur J Clin Microbiol Infect Dis. 2018 Feb;37(2):209-226. doi: 10.1007/s10096-017-3111-8. Epub 2017 Oct 5. Review.

PMID:
28980148
20.

Chronic pain as a human rights issue: setting an agenda for preventative action.

Frenkel L, Swartz L.

Glob Health Action. 2017;10(1):1348691. doi: 10.1080/16549716.2017.1348691.

21.

Genetic analyses of HIV env associated with uveitis in antiretroviral-naive individuals.

Williams-Wietzikoski CA, So ID, Bull ME, Samleerat T, Pathanapitoon K, Kunavisarut P, Kongyai N, Ngo-Giang-Huong N, Frenkel LM, Sirirungsi W.

AIDS. 2017 Aug 24;31(13):1825-1830. doi: 10.1097/QAD.0000000000001550.

22.

Clonal Expansion of Human Immunodeficiency Virus-Infected Cells and Human Immunodeficiency Virus Persistence During Antiretroviral Therapy.

Mullins JI, Frenkel LM.

J Infect Dis. 2017 Mar 15;215(suppl_3):S119-S127. doi: 10.1093/infdis/jiw636. Review.

PMID:
28520966
23.

Organization of Circadian Behavior Relies on Glycinergic Transmission.

Frenkel L, Muraro NI, Beltrán González AN, Marcora MS, Bernabó G, Hermann-Luibl C, Romero JI, Helfrich-Förster C, Castaño EM, Marino-Busjle C, Calvo DJ, Ceriani MF.

Cell Rep. 2017 Apr 4;19(1):72-85. doi: 10.1016/j.celrep.2017.03.034.

24.

Persistence of HIV drug resistance among South African children given nevirapine to prevent mother-to-child-transmission.

Kanthula R, Rossouw TM, Feucht UD, van Dyk G, Beck IA, Silverman R, Olson S, Salyer C, Cassol S, Frenkel LM.

AIDS. 2017 May 15;31(8):1143-1148. doi: 10.1097/QAD.0000000000001446.

25.

H1N1 influenza vaccination in HIV-infected women on effective antiretroviral treatment did not induce measurable antigen-driven proliferation of the HIV-1 proviral reservoir.

Wagner TA, Huang HC, Salyer CE, Richardson KM, Weinberg A, Nachman S, Frenkel LM.

AIDS Res Ther. 2017 Feb 13;14(1):7. doi: 10.1186/s12981-017-0135-1.

26.

HIV Transmission During Condomless Sex With a Seropositive Partner With Suppressed Infection.

Goldman JD, Frenkel LM, Mullins JI.

JAMA. 2016 Nov 15;316(19):2044-2045. doi: 10.1001/jama.2016.16030. No abstract available.

PMID:
27838715
27.

Short Communication: Phylogenetic Evidence of HIV-1 Transmission Between Adult and Adolescent Men Who Have Sex with Men.

Wolf E, Herbeck JT, Van Rompaey S, Kitahata M, Thomas K, Pepper G, Frenkel L.

AIDS Res Hum Retroviruses. 2017 Apr;33(4):318-322. doi: 10.1089/AID.2016.0061. Epub 2016 Nov 1.

28.

Electronic health records-Applications for the allergist/immunologist: All that glitters is not gold.

Frenkel LD.

Allergy Asthma Proc. 2016 Jul;37(4):273-8. doi: 10.2500/aap.2016.37.3959. Review.

PMID:
27401314
29.

Comparing Congenital Zika and Cytomegalovirus Affliction.

Frenkel LD.

Pediatr Infect Dis J. 2016 Dec;35(12):1371-1372. No abstract available.

PMID:
27286563
30.

Joseph A. Bellanti, MD, FAAP, FACAAI, FAAAAI.

Frenkel LD.

Ann Allergy Asthma Immunol. 2016 Jul;117(1):1-8. doi: 10.1016/j.anai.2016.04.015. Epub 2016 May 24. No abstract available.

PMID:
27234938
31.

Comparison of Matrix-Based and Filter Paper-Based Systems for Transport of Plasma for HIV-1 RNA Quantification and Amplicon Preparation for Genotyping.

Levine M, Beck I, Styrchak S, Pepper G, Frenkel L.

J Clin Microbiol. 2016 Jul;54(7):1899-1901. doi: 10.1128/JCM.00541-16. Epub 2016 Apr 13.

32.

Increasing HIV-1 pretreatment drug resistance among antiretroviral-naïve adults initiating treatment between 2006 and 2014 in Nairobi, Kenya.

Chung MH, Silverman R, Beck IA, Yatich N, Dross S, McKernan-Mullin J, Bii S, Tapia K, Stern J, Chohan B, Sakr SR, Kiarie JN, Frenkel LM.

AIDS. 2016 Jun 19;30(10):1680-2. doi: 10.1097/QAD.0000000000001110.

33.

Development and validation of an oligonucleotide ligation assay to detect lamivudine resistance in hepatitis B virus.

Beck IA, Payant R, Ngo-Giang-Huong N, Khamduang W, Laomanit L, Jourdain G, Frenkel LM.

J Virol Methods. 2016 Jul;233:51-5. doi: 10.1016/j.jviromet.2016.03.014. Epub 2016 Mar 26.

34.

'This place is making me more depressed': The organisation of care for suicide attempters in a South African hospital.

Bantjes J, Nel A, Louw KA, Frenkel L, Benjamin E, Lewis I.

J Health Psychol. 2017 Sep;22(11):1434-1446. doi: 10.1177/1359105316628744. Epub 2016 Feb 22.

PMID:
26903076
35.

Simplified Paper Format for Detecting HIV Drug Resistance in Clinical Specimens by Oligonucleotide Ligation.

Panpradist N, Beck IA, Chung MH, Kiarie JN, Frenkel LM, Lutz BR.

PLoS One. 2016 Jan 11;11(1):e0145962. doi: 10.1371/journal.pone.0145962. eCollection 2016.

36.

HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.

Rhee SY, Jordan MR, Raizes E, Chua A, Parkin N, Kantor R, Van Zyl GU, Mukui I, Hosseinipour MC, Frenkel LM, Ndembi N, Hamers RL, Rinke de Wit TF, Wallis CL, Gupta RK, Fokam J, Zeh C, Schapiro JM, Carmona S, Katzenstein D, Tang M, Aghokeng AF, De Oliveira T, Wensing AM, Gallant JE, Wainberg MA, Richman DD, Fitzgibbon JE, Schito M, Bertagnolio S, Yang C, Shafer RW.

PLoS One. 2015 Dec 30;10(12):e0145772. doi: 10.1371/journal.pone.0145772. eCollection 2015.

37.

Pharmacokinetics and 48-Week Safety and Efficacy of Raltegravir for Oral Suspension in Human Immunodeficiency Virus Type-1-Infected Children 4 Weeks to 2 Years of Age.

Nachman S, Alvero C, Acosta EP, Teppler H, Homony B, Graham B, Fenton T, Xu X, Rizk ML, Spector SA, Frenkel LM, Worrell C, Handelsman E, Wiznia A.

J Pediatric Infect Dis Soc. 2015 Dec;4(4):e76-83. doi: 10.1093/jpids/piu146. Epub 2015 Feb 7.

38.

Short Communication: Analysis of Minor Populations of Human Immunodeficiency Virus by Primer Identification and Insertion-Deletion and Carry Forward Correction Pipelines.

Hughes P, Deng W, Olson SC, Coombs RW, Chung MH, Frenkel LM.

AIDS Res Hum Retroviruses. 2016 Mar;32(3):296-302. doi: 10.1089/AID.2015.0202. Epub 2015 Dec 15.

39.

Risk of congenital cytomegalovirus infection among HIV-exposed uninfected infants is not decreased by maternal nelfinavir use during pregnancy.

Gantt S, Leister E, Jacobsen DL, Boucoiran I, Huang ML, Jerome KR, Jourdain G, Ngo-Giang-Huong N, Burchett S, Frenkel L.

J Med Virol. 2016 Jun;88(6):1051-8. doi: 10.1002/jmv.24420. Epub 2015 Nov 18.

40.

Biomarkers of inflammation in HIV-infected Peruvian men and women before and during suppressive antiretroviral therapy.

Ticona E, Bull ME, Soria J, Tapia K, Legard J, Styrchak SM, Williams C, Mitchell C, La Rosa A, Rosa AL, Coombs RW, Frenkel LM.

AIDS. 2015 Aug 24;29(13):1617-22. doi: 10.1097/QAD.0000000000000758. Erratum in: AIDS. 2015 Sep 24;29(15):2065. Rosa, Alberto L A [corrected to La Rosa, Alberto].

41.

Resistance detected by pyrosequencing following zidovudine monotherapy for prevention of HIV-1 mother-to-child-transmission.

Olson SC, Ngo-Giang-Huong N, Beck I, Deng W, Britto P, Shapiro DE, Bumgarner RE, Mullins JI, Van Dyke RB, Jourdain G, Frenkel LM.

AIDS. 2015 Jul 31;29(12):1467-71. doi: 10.1097/QAD.0000000000000737.

42.

Editorial Commentary: Oral Polio Vaccine at Birth.

Frenkel LD.

Clin Infect Dis. 2015 Nov 15;61(10):1512-3. doi: 10.1093/cid/civ619. Epub 2015 Jul 28. No abstract available.

PMID:
26219692
43.

Ethics of HIV research in children.

Rossouw TM, Crane J, Frenkel LM.

Lancet Infect Dis. 2015 Jun;15(6):634-5. doi: 10.1016/S1473-3099(15)00023-7. Epub 2015 May 17. No abstract available.

44.

Risk of drug resistance among persons acquiring HIV within a randomized clinical trial of single- or dual-agent preexposure prophylaxis.

Lehman DA, Baeten JM, McCoy CO, Weis JF, Peterson D, Mbara G, Donnell D, Thomas KK, Hendrix CW, Marzinke MA, Frenkel L, Ndase P, Mugo NR, Celum C, Overbaugh J, Matsen FA; Partners PrEP Study Team.

J Infect Dis. 2015 Apr 15;211(8):1211-8. doi: 10.1093/infdis/jiu677. Epub 2015 Jan 13.

45.

Preexposure prophylaxis is efficacious for HIV-1 prevention among women using depot medroxyprogesterone acetate for contraception.

Heffron R, Mugo N, Were E, Kiarie J, Bukusi EA, Mujugira A, Frenkel LM, Donnell D, Ronald A, Celum C, Baeten JM; Partners PrEP Study Team.

AIDS. 2014 Nov 28;28(18):2771-6. doi: 10.1097/QAD.0000000000000493.

46.

Emerging antiretroviral drug resistance in sub-Saharan Africa: novel affordable technologies are needed to provide resistance testing for individual and public health benefits.

van Zyl GU, Frenkel LM, Chung MH, Preiser W, Mellors JW, Nachega JB.

AIDS. 2014 Nov 28;28(18):2643-8. doi: 10.1097/QAD.0000000000000502. No abstract available.

47.

Autocrine/paracrine function of globular adiponectin: inhibition of lipid metabolism and inflammatory response in 3T3-L1 adipocytes.

Lazra Y, Falach A, Frenkel L, Rozenberg K, Sampson S, Rosenzweig T.

J Cell Biochem. 2015 May;116(5):754-66. doi: 10.1002/jcb.25031.

PMID:
25491932
48.

Single-agent tenofovir versus combination emtricitabine plus tenofovir for pre-exposure prophylaxis for HIV-1 acquisition: an update of data from a randomised, double-blind, phase 3 trial.

Baeten JM, Donnell D, Mugo NR, Ndase P, Thomas KK, Campbell JD, Wangisi J, Tappero JW, Bukusi EA, Cohen CR, Katabira E, Ronald A, Tumwesigye E, Were E, Fife KH, Kiarie J, Farquhar C, John-Stewart G, Kidoguchi L, Coombs RW, Hendrix C, Marzinke MA, Frenkel L, Haberer JE, Bangsberg D, Celum C; Partners PrEP Study Team.

Lancet Infect Dis. 2014 Nov;14(11):1055-1064. doi: 10.1016/S1473-3099(14)70937-5. Epub 2014 Oct 7.

49.

Variable and suboptimal nevirapine levels in infants given single-dose nevirapine at birth without maternal prophylaxis.

Dross SE, Rossi SS, Beck IA, Micek MA, Blanco AJ, Seidel KD, Montoya P, Capparelli EV, Frenkel LM.

AIDS. 2014 Oct 23;28(16):2491-3. doi: 10.1097/QAD.0000000000000451. No abstract available.

50.

Optimization of the oligonucleotide ligation assay for the detection of nevirapine resistance mutations in Zimbabwean Human Immunodeficiency Virus type-1 subtype C.

Mutsvangwa J, Beck IA, Gwanzura L, Manhanzva MT, Stranix-Chibanda L, Chipato T, Frenkel LM.

J Virol Methods. 2014 Dec 15;210:36-9. doi: 10.1016/j.jviromet.2014.09.005. Epub 2014 Sep 17.

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