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Items: 43


Cwf16p Associating with the Nineteen Complex Ensures Ordered Exon Joining in Constitutive Pre-mRNA Splicing in Fission Yeast.

Sasaki-Haraguchi N, Ikuyama T, Yoshii S, Takeuchi-Andoh T, Frendewey D, Tani T.

PLoS One. 2015 Aug 24;10(8):e0136336. doi: 10.1371/journal.pone.0136336. eCollection 2015.


Diverse Phenotypes and Specific Transcription Patterns in Twenty Mouse Lines with Ablated LincRNAs.

Lai KM, Gong G, Atanasio A, Rojas J, Quispe J, Posca J, White D, Huang M, Fedorova D, Grant C, Miloscio L, Droguett G, Poueymirou WT, Auerbach W, Yancopoulos GD, Frendewey D, Rinn J, Valenzuela DM.

PLoS One. 2015 Apr 24;10(4):e0125522. doi: 10.1371/journal.pone.0125522. eCollection 2015.


Generation of fertile and fecund F0 XY female mice from XY ES cells.

Kuno J, Poueymirou WT, Gong G, Siao CJ, Clarke G, Esau L, Kojak N, Posca J, Atanasio A, Strein J, Yancopoulos GD, Lai KM, DeChiara TM, Frendewey D, Auerbach W, Valenzuela DM.

Transgenic Res. 2015 Feb;24(1):19-29. doi: 10.1007/s11248-014-9815-y. Epub 2014 Aug 3.


Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes.

Macdonald LE, Karow M, Stevens S, Auerbach W, Poueymirou WT, Yasenchak J, Frendewey D, Valenzuela DM, Giallourakis CC, Alt FW, Yancopoulos GD, Murphy AJ.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5147-52. doi: 10.1073/pnas.1323896111. Epub 2014 Mar 25.


Multiple knockout mouse models reveal lincRNAs are required for life and brain development.

Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, Moore JC, Lai V, Gong G, Yancopoulos GD, Frendewey D, Kellis M, Hart RP, Valenzuela DM, Arlotta P, Rinn JL.

Elife. 2013 Dec 31;2:e01749. doi: 10.7554/eLife.01749.


Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution.

Chandramouli A, Simundza J, Pinderhughes A, Hiremath M, Droguett G, Frendewey D, Cowin P.

Breast Cancer Res. 2013 Nov 21;15(6):R111. doi: 10.1186/bcr3578.


Conditionals by inversion provide a universal method for the generation of conditional alleles.

Economides AN, Frendewey D, Yang P, Dominguez MG, Dore AT, Lobov IB, Persaud T, Rojas J, McClain J, Lengyel P, Droguett G, Chernomorsky R, Stevens S, Auerbach W, Dechiara TM, Pouyemirou W, Cruz JM Jr, Feeley K, Mellis IA, Yasenchack J, Hatsell SJ, Xie L, Latres E, Huang L, Zhang Y, Pefanis E, Skokos D, Deckelbaum RA, Croll SD, Davis S, Valenzuela DM, Gale NW, Murphy AJ, Yancopoulos GD.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3179-88. doi: 10.1073/pnas.1217812110. Epub 2013 Aug 5.


The mammalian gene function resource: the International Knockout Mouse Consortium.

Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W.

Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12.


The loss-of-allele assay for ES cell screening and mouse genotyping.

Frendewey D, Chernomorsky R, Esau L, Om J, Xue Y, Murphy AJ, Yancopoulos GD, Valenzuela DM.

Methods Enzymol. 2010;476:295-307. doi: 10.1016/S0076-6879(10)76017-1.


Producing fully ES cell-derived mice from eight-cell stage embryo injections.

DeChiara TM, Poueymirou WT, Auerbach W, Frendewey D, Yancopoulos GD, Valenzuela DM.

Methods Enzymol. 2010;476:285-94. doi: 10.1016/S0076-6879(10)76016-X.


VelociMouse: fully ES cell-derived F0-generation mice obtained from the injection of ES cells into eight-cell-stage embryos.

Dechiara TM, Poueymirou WT, Auerbach W, Frendewey D, Yancopoulos GD, Valenzuela DM.

Methods Mol Biol. 2009;530:311-24. doi: 10.1007/978-1-59745-471-1_16.


Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.

Todorovic V, Frendewey D, Gutstein DE, Chen Y, Freyer L, Finnegan E, Liu F, Murphy A, Valenzuela D, Yancopoulos G, Rifkin DB.

Development. 2007 Oct;134(20):3723-32. Epub 2007 Sep 5.


Regulation of the germinal center response by microRNA-155.

Thai TH, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL, Schmidt-Supprian M, Rajewsky N, Yancopoulos G, Rao A, Rajewsky K.

Science. 2007 Apr 27;316(5824):604-8.


F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses.

Poueymirou WT, Auerbach W, Frendewey D, Hickey JF, Escaravage JM, Esau L, Doré AT, Stevens S, Adams NC, Dominguez MG, Gale NW, Yancopoulos GD, DeChiara TM, Valenzuela DM.

Nat Biotechnol. 2007 Jan;25(1):91-9. Epub 2006 Dec 24.


Mutations in the SF1-U2AF59-U2AF23 complex cause exon skipping in Schizosaccharomyces pombe.

Haraguchi N, Andoh T, Frendewey D, Tani T.

J Biol Chem. 2007 Jan 26;282(4):2221-8. Epub 2006 Nov 27.


Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.

Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yancopoulos GD, Alt FW.

Cell. 2006 Jan 27;124(2):315-29.


Functional significance of intermediate cleavages in the 3'ETS of the pre-rRNA from Schizosaccharomyces pombe.

Ivakine E, Spasov K, Frendewey D, Nazar RN.

Nucleic Acids Res. 2003 Dec 15;31(24):7110-6.


High-throughput engineering of the mouse genome coupled with high-resolution expression analysis.

Valenzuela DM, Murphy AJ, Frendewey D, Gale NW, Economides AN, Auerbach W, Poueymirou WT, Adams NC, Rojas J, Yasenchak J, Chernomorsky R, Boucher M, Elsasser AL, Esau L, Zheng J, Griffiths JA, Wang X, Su H, Xue Y, Dominguez MG, Noguera I, Torres R, Macdonald LE, Stewart AF, DeChiara TM, Yancopoulos GD.

Nat Biotechnol. 2003 Jun;21(6):652-9. Epub 2003 May 5.


Ribonuclease activity and RNA binding of recombinant human Dicer.

Provost P, Dishart D, Doucet J, Frendewey D, Samuelsson B, Rådmark O.

EMBO J. 2002 Nov 1;21(21):5864-74.


Pac1 ribonuclease of Schizosaccharomyces pombe.

Rotondo G, Frendewey D.

Methods Enzymol. 2001;342:168-93. No abstract available.


Myb-related fission yeast cdc5p is a component of a 40S snRNP-containing complex and is essential for pre-mRNA splicing.

McDonald WH, Ohi R, Smelkova N, Frendewey D, Gould KL.

Mol Cell Biol. 1999 Aug;19(8):5352-62.


Cell-division-cycle defects associated with fission yeast pre-mRNA splicing mutants.

Potashkin J, Kim D, Fons M, Humphrey T, Frendewey D.

Curr Genet. 1998 Sep;34(3):153-63.


A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase.

Lundgren K, Allan S, Urushiyama S, Tani T, Ohshima Y, Frendewey D, Beach D.

Mol Biol Cell. 1996 Jul;7(7):1083-94.


Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe.

Rotondo G, Frendewey D.

Nucleic Acids Res. 1996 Jun 15;24(12):2377-86.


Rescue of the fission yeast snRNA synthesis mutant snm1 by overexpression of the double-strand-specific Pac1 ribonuclease.

Rotondo G, Gillespie M, Frendewey D.

Mol Gen Genet. 1995 Jun 25;247(6):698-708.


Schizosaccharomyces U6 genes have a sequence within their introns that matches the B box consensus of tRNA internal promoters.

Frendewey D, Barta I, Gillespie M, Potashkin J.

Nucleic Acids Res. 1990 Apr 25;18(8):2025-32.


Splicing of the U6 RNA precursor is impaired in fission yeast pre-mRNA splicing mutants.

Potashkin J, Frendewey D.

Nucleic Acids Res. 1989 Oct 11;17(19):7821-31.


Pre-mRNA splicing mutants of Schizosaccharomyces pombe.

Potashkin J, Li R, Frendewey D.

EMBO J. 1989 Feb;8(2):551-9.


Use of RNase H and primer extension to analyze RNA splicing.

Erster SH, Finn LA, Frendewey DA, Helfman DM.

Nucleic Acids Res. 1988 Jul 11;16(13):5999-6014.


Different small nuclear ribonucleoprotein particles are involved in different steps of splicing complex formation.

Frendewey D, Krämer A, Keller W.

Cold Spring Harb Symp Quant Biol. 1987;52:287-98. No abstract available.


Two RNA species co-purify with RNase P from the fission yeast Schizosaccharomyces pombe.

Krupp G, Cherayil B, Frendewey D, Nishikawa S, Söll D.

EMBO J. 1986 Jul;5(7):1697-703.


A single base change in the intron of a serine tRNA affects the rate of RNase P cleavage in vitro and suppressor activity in vivo in Saccharomyces cerevisiae.

Willis I, Frendewey D, Nichols M, Hottinger-Werlen A, Schaack J, Söll D.

J Biol Chem. 1986 May 5;261(13):5878-85.


Specific incorporation of 5-fluorocytidine into Escherichia coli RNA.

Kaiser II, Kladianos DM, Frendewey DA.

Biochim Biophys Acta. 1985 May 24;825(1):12-20.


The Schizosaccharomyces pombe sup3-i suppressor recognizes ochre, but not amber codons in vitro and in vivo.

Hottinger H, Stadelmann B, Pearson D, Frendewey D, Kohli J, Söll D.

EMBO J. 1984 Feb;3(2):423-8.


Effects of 5-fluorouracil on base modification in Escherichia coli tRNA.

Frendewey DA, Kaiser II.

Biochemistry. 1979 Jul 10;18(14):3179-85. No abstract available.


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