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Efficacy of Omalizumab in Mastocytosis: Allusive Indication Obtained from a Prospective, Double-Blind, Multicenter Study (XOLMA Study).

Distler M, Maul JT, Steiner UC, Jandus P, Kolios AGA, Murer C, Graf N, Seebach JD, Pichler WJ, Navarini AA, French LE, Helbling A, Schmid-Grendelmeier P.

Dermatology. 2020 Jan 20:1-11. doi: 10.1159/000504842. [Epub ahead of print]


Coexistence of Oncogenic Human Papillomavirus Genotypes in Condylomata Acuminata among Children and Adolescents.

Marsela E, Fischbeck AJ, Hildebrand JA, Aoki R, French LE, Wollenberg A, Schmoeckel E, Reinholz M.

Acta Derm Venereol. 2020 Jan 17. doi: 10.2340/00015555-3407. [Epub ahead of print] No abstract available.


Microneedling-assisted photodynamic therapy for the treatment of actinic keratosis: Results from a systematic review and meta-analysis.

Steeb T, Niesert AC, French LE, Berking C, Heppt MV.

J Am Acad Dermatol. 2020 Feb;82(2):515-519. doi: 10.1016/j.jaad.2019.09.037. No abstract available.


Methods for extraction and ex-vivo experimentation with the most complex human commensal, Demodex spp.

Clanner-Engelshofen BM, French LE, Reinholz M.

Exp Appl Acarol. 2020 Jan;80(1):59-70. doi: 10.1007/s10493-019-00450-9. Epub 2019 Dec 13.


IL-36γ drives skin toxicity induced by EGFR/MEK inhibition and commensal Cutibacterium acnes.

Satoh TK, Mellett M, Meier-Schiesser B, Fenini G, Otsuka A, Beer HD, Rordorf T, Maul JT, Hafner J, Navarini AA, Contassot E, French LE.

J Clin Invest. 2019 Dec 5. pii: 128678. doi: 10.1172/JCI128678. [Epub ahead of print]


Recurrence of Pemphigus Vulgaris Under Nivolumab Therapy.

Krammer S, Krammer C, Salzer S, Bağci IS, French LE, Hartmann D.

Front Med (Lausanne). 2019 Nov 12;6:262. doi: 10.3389/fmed.2019.00262. eCollection 2019.


Corynebacterium kroppenstedtii subsp. demodicis is the endobacterium of Demodex folliculorum.

Clanner-Engelshofen BM, French LE, Reinholz M.

J Eur Acad Dermatol Venereol. 2019 Nov 12. doi: 10.1111/jdv.16069. [Epub ahead of print]


Corrigendum to 'Prediction of melanoma evolution in melanocytic nevi via artificial intelligence: A call for prospective data' [Eur J Cancer, 119 (September 2019) Pages 30-34].

Sondermann W, Utikal JS, Enk AH, Schadendorf D, Klode J, Hauschild A, Weichenthal M, French LE, Berking C, Schilling B, Haferkamp S, Fröhling S, von Kalle C, Brinker TJ.

Eur J Cancer. 2019 Dec;123:171. doi: 10.1016/j.ejca.2019.10.003. Epub 2019 Nov 7. No abstract available.


Diode lasers for the treatment of genital warts.

Alharbi R, Clanner-Engelshofen B, Hildebrand JA, Schinabeck-Kühne N, Niculescu L, French LE, Kaudewitz P, Reinholz M.

Eur J Dermatol. 2019 Aug 1;29(4):409-416. doi: 10.1684/ejd.2019.3600.


Comparative analysis of the phototoxicity induced by BRAF inhibitors and alleviation through antioxidants.

Heppt MV, Clanner-Engelshofen BM, Marsela E, Wessely A, Kammerbauer C, Przybilla B, French LE, Berking C, Reinholz M.

Photodermatol Photoimmunol Photomed. 2019 Oct 16. doi: 10.1111/phpp.12520. [Epub ahead of print]


Harmonisation of Outcome Parameters and Evaluation (HOPE) for actinic keratosis: protocol for the development of a core outcome set.

Heppt MV, Steeb T, Schmitz L, Garbe C, French LE, Leiter U, Berking C.

Trials. 2019 Oct 11;20(1):589. doi: 10.1186/s13063-019-3696-6.


Long-term efficacy of interventions for actinic keratosis: protocol for a systematic review and network meta-analysis.

Steeb T, Heppt MV, Becker L, Kohl C, French LE, Berking C.

Syst Rev. 2019 Oct 11;8(1):237. doi: 10.1186/s13643-019-1156-8.


The more the better? An appraisal of combination therapies for actinic keratosis.

Steeb T, Wessely A, Leiter U, French LE, Berking C, Heppt MV.

J Eur Acad Dermatol Venereol. 2019 Oct 6. doi: 10.1111/jdv.15998. [Epub ahead of print] Review.


Linkage between patients' characteristics and prescribed systemic treatments for psoriasis: a semantic connectivity map analysis of the Swiss Dermatology Network for Targeted Therapies registry.

Cazzaniga S, Anzengruber F, Augustin M, Boehncke WH, Borradori L, Conrad C, Cozzio A, Djamei V, French LE, Gilliet M, Häusermann P, Heidemeyer K, Itin P, Kolios AGA, Laffitte E, Maul JT, Mainetti C, Naldi L, Navarini AA, Rustenbach SJ, Simon D, Sorbe C, Streit M, Yawalkar N.

J Eur Acad Dermatol Venereol. 2019 Dec;33(12):2313-2318. doi: 10.1111/jdv.15983. Epub 2019 Oct 28.


Uniparental Disomy of Chromosome 2 Unmasks New ITGA6 Recessive Mutation and Results in a Lethal Junctional Epidermolysis Bullosa in a Newborn.

Higgins R, Jensen AN, Wachstein J, Bruckner-Tuderman L, Spiegel R, Traber H, Achermann J, Schaller M, Fehrenbacher B, Röcken M, Ignatova D, Chang YT, Fischer T, Schwieger-Briel AE, French LE, Hoetzenecker W, Hornung R, Malzacher A, Cozzio A, Navarini A, Has C, Guenova E.

Acta Derm Venereol. 2019 Sep 10. doi: 10.2340/00015555-3313. [Epub ahead of print] No abstract available.


Retrospective analysis of alpha-human papillomavirus (HPV) types in tissue samples from anogenital dysplasias - introduction of the RICH (Risk of HPV-related Carcinoma in HIV+/- patients) score.

Hildebrand JA, Fischbeck AJ, Hundsdoerfer B, Clanner-Engelshofen BM, Marsela E, Wollenberg A, Flaig M, French LE, Reinholz M.

J Eur Acad Dermatol Venereol. 2019 Sep 8. doi: 10.1111/jdv.15932. [Epub ahead of print]


A systematic review of factors influencing treatment adherence in chronic inflammatory skin disease - strategies for optimizing treatment outcome.

Eicher L, Knop M, Aszodi N, Senner S, French LE, Wollenberg A.

J Eur Acad Dermatol Venereol. 2019 Dec;33(12):2253-2263. doi: 10.1111/jdv.15913. Epub 2019 Nov 14. Review.


Prediction of melanoma evolution in melanocytic nevi via artificial intelligence: A call for prospective data.

Sondermann W, Utikal JS, Enk AH, Schadendorf D, Klode J, Hauschild A, Weichenthal M, French LE, Berking C, Schilling B, Haferkamp S, Fröhling S, von Kalle C, Brinker TJ.

Eur J Cancer. 2019 Sep;119:30-34. doi: 10.1016/j.ejca.2019.07.009. Epub 2019 Aug 8. Erratum in: Eur J Cancer. 2019 Dec;123:171.


Patient Attitudes and Their Awareness Towards Skin Cancer-Related Apps: Cross-Sectional Survey.

Steeb T, Wessely A, Mastnik S, Brinker TJ, French LE, Niesert AC, Berking C, Heppt MV.

JMIR Mhealth Uhealth. 2019 Jul 2;7(7):e13844. doi: 10.2196/13844.


Ex vivo confocal laser scanning microscopy for bullous pemphigoid diagnostics: new era in direct immunofluorescence?

Bağcı IS, Aoki R, Krammer S, Ruzicka T, Sárdy M, French LE, Hartmann D.

J Eur Acad Dermatol Venereol. 2019 Nov;33(11):2123-2130. doi: 10.1111/jdv.15767. Epub 2019 Jul 22.


Skin Cancer Smartphone Applications for German-speaking Patients: Review and Content Analysis Using the Mobile App Rating Scale.

Steeb T, Wessely A, French LE, Heppt MV, Berking C.

Acta Derm Venereol. 2019 Oct 1;99(11):1043-1044. doi: 10.2340/00015555-3240. No abstract available.


A new link between autoinflammation and hidradenitis suppurativa?

Contassot E, French LE.

Br J Dermatol. 2019 Jun;180(6):1294-1295. doi: 10.1111/bjd.17908. No abstract available.


Design of in vitro Transcribed mRNA Vectors for Research and Therapy.

Tusup M, French LE, De Matos M, Gatfield D, Kundig T, Pascolo S.

Chimia (Aarau). 2019 May 29;73(6):391-394. doi: 10.2533/chimia.2019.391. Review.


Smoking does not Alter the Therapy Response to Systemic Anti-psoriatic Therapies: A Two-country, Multi-centre, Prospective, Non-interventional Study.

Anzengruber F, Augustin M, Radtke MA, Thaci D, Yawalkar N, Streit M, Reich K, Drach M, Sorbe C, French LE, Mrowietz U, Maul JT, Itin PH, Navarini AA.

Acta Derm Venereol. 2019 Sep 1;99(10):871-877. doi: 10.2340/00015555-3221.


Subcutaneous White Adipose Tissue of Healthy Young Individuals Harbors a Leukocyte Compartment Distinct from Skin and Blood.

Brüggen MC, Strobl J, Koszik F, Naito R, Vierhapper M, Li N, Stary G, Kiprov H, French LE, Stingl G.

J Invest Dermatol. 2019 Sep;139(9):2052-2055.e7. doi: 10.1016/j.jid.2019.02.034. Epub 2019 Apr 8. No abstract available.


Nickel contact dermatitis evaluated by means of optical coherence tomography: first impressions.

Ruini C, Wittmann D, Summer B, von Braunmühl T, French LE, Thomas P.

J Eur Acad Dermatol Venereol. 2019 Jul;33(7):e265-e267. doi: 10.1111/jdv.15536. Epub 2019 Mar 19. No abstract available.


The NLRP1 Inflammasome Pathway Is Silenced in Cutaneous Squamous Cell Carcinoma.

Sand J, Fenini G, Grossi S, Hennig P, Di Filippo M, Levesque M, Werner S, French LE, Beer HD.

J Invest Dermatol. 2019 Aug;139(8):1788-1797.e6. doi: 10.1016/j.jid.2019.01.025. Epub 2019 Feb 7.


Divergent LAG-3 versus BTLA, TIGIT, and FCRL3 expression in Sézary syndrome.

Anzengruber F, Ignatova D, Schlaepfer T, Chang YT, French LE, Pascolo S, Contassot E, Bobrowicz M, Hoetzenecker W, Guenova E.

Leuk Lymphoma. 2019 Aug;60(8):1899-1907. doi: 10.1080/10428194.2018.1564827. Epub 2019 Jan 14.


Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing.

Anzengruber F, Alotaibi F, Kaufmann LS, Ghosh A, Oswald MR, Maul JT, Meier B, French LE, Bonmarin M, Navarini AA.

Allergol Int. 2019 Apr;68(2):254-258. doi: 10.1016/j.alit.2018.12.001. Epub 2018 Dec 29.


Interferon alfa-2a maintenance after salvage autologous stem cell transplantation in atypical mycosis fungoides with central nervous system involvement.

Doerschner M, Pekar-Lukacs A, Messerli-Odermatt O, Dommann-Scherrer C, Rütti M, Müller AM, Nair G, Kamarachev J, Kerl K, Beer M, Messerli M, Frauenknecht K, Haralambieva E, Hoetzenecker W, French LE, Guenova E.

Br J Dermatol. 2019 Dec;181(6):1296-1302. doi: 10.1111/bjd.17535. Epub 2019 Mar 4.


Culprit Drugs Induce Specific IL-36 Overexpression in Acute Generalized Exanthematous Pustulosis.

Meier-Schiesser B, Feldmeyer L, Jankovic D, Mellett M, Satoh TK, Yerly D, Navarini A, Abe R, Yawalkar N, Chung WH, French LE, Contassot E.

J Invest Dermatol. 2019 Apr;139(4):848-858. doi: 10.1016/j.jid.2018.10.023. Epub 2018 Nov 2.


Gender and age significantly determine patient needs and treatment goals in psoriasis - a lesson for practice.

Maul JT, Navarini AA, Sommer R, Anzengruber F, Sorbe C, Mrowietz U, Drach M, Blome C, Boehncke WH, Thaci D, Reich K, von Kiedrowski R, Körber A, Yawalkar N, Mainetti C, Laffitte E, Streit M, Rustenbach S, Conrad C, Borradori L, Gilliet M, Cozzio A, Itin P, Häusermann P, French LE, Radtke MA, Augustin M.

J Eur Acad Dermatol Venereol. 2019 Apr;33(4):700-708. doi: 10.1111/jdv.15324. Epub 2019 Jan 15.


Teledermatology: Comparison of Store-and-Forward Versus Live Interactive Video Conferencing.

Brinker TJ, Hekler A, von Kalle C, Schadendorf D, Esser S, Berking C, Zacher MT, Sondermann W, Grabe N, Steeb T, Utikal JS, French LE, Enk AH.

J Med Internet Res. 2018 Oct 24;20(10):e11871. doi: 10.2196/11871.


[Painful lymphadenopathy after an insect bite-a case report].

Vukovic S, Anagnostopoulos A, Zbinden R, Schönenberger L, Guillod C, French LE, Navarini A, Roider E.

Hautarzt. 2019 Jan;70(1):47-50. doi: 10.1007/s00105-018-4237-z. German.


Topical resiquimod dosing regimens in patients with multiple actinic keratoses: a multicentre, partly placebo-controlled, double-blind clinical trial.

Stockfleth E, Hofbauer GFL, Reinhold U, Popp G, Hengge UR, Szeimies RM, Brüning H, Anliker M, Hunger T, Dummer R, Ulrich C, Kenzelmann R, Surber C, French LE.

Br J Dermatol. 2019 Feb;180(2):297-305. doi: 10.1111/bjd.17124. Epub 2018 Oct 22.


Mechanisms Underlying the Clinical Effects of Apremilast for Psoriasis.

Pincelli C, Schafer PH, French LE, Augustin M, Krueger JG.

J Drugs Dermatol. 2018 Aug 1;17(8):835-840. Review.


Genome Editing of Human Primary Keratinocytes by CRISPR/Cas9 Reveals an Essential Role of the NLRP1 Inflammasome in UVB Sensing.

Fenini G, Grossi S, Contassot E, Biedermann T, Reichmann E, French LE, Beer HD.

J Invest Dermatol. 2018 Dec;138(12):2644-2652. doi: 10.1016/j.jid.2018.07.016. Epub 2018 Aug 7.


Inflammation: A Contributor to Depressive Comorbidity in Inflammatory Skin Disease.

Farzanfar D, Dowlati Y, French LE, Lowes MA, Alavi A.

Skin Pharmacol Physiol. 2018;31(5):246-251. doi: 10.1159/000490002. Epub 2018 Jun 28. Review.


Cytokine Release Syndrome During Sequential Treatment With Immune Checkpoint Inhibitors and Kinase Inhibitors for Metastatic Melanoma.

Dimitriou F, Matter AV, Mangana J, Urosevic-Maiwald M, Micaletto S, Braun RP, French LE, Dummer R.

J Immunother. 2019 Jan;42(1):29-32. doi: 10.1097/CJI.0000000000000236.


PD-L1 expression is an independent predictor of favorable outcome in patients with localized esophageal adenocarcinoma.

Kollmann D, Ignatova D, Jedamzik J, Chang YT, Jomrich G, Baierl A, Kazakov D, Michal M, French LE, Hoetzenecker W, Schatton T, Asari R, Preusser M, Gnant M, Guenova E, Schoppmann SF.

Oncoimmunology. 2018 Mar 13;7(6):e1435226. doi: 10.1080/2162402X.2018.1435226. eCollection 2018.


Aggressive Rare T-cell Lymphomas with Manifestation in the Skin: A Monocentric Cross-sectional Case Study.

Brüggen MC, Kerl K, Haralambieva E, Schanz U, Chang YT, Ignatova D, Dummer R, Cozzio A, Hoetzenecker W, French LE, Guenova E.

Acta Derm Venereol. 2018 Oct 10;98(9):835-841. doi: 10.2340/00015555-2950.


CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo.

Mellett M, Meier B, Mohanan D, Schairer R, Cheng P, Satoh TK, Kiefer B, Ospelt C, Nobbe S, Thome M, Contassot E, French LE.

J Invest Dermatol. 2018 Sep;138(9):2010-2023. doi: 10.1016/j.jid.2018.03.1525. Epub 2018 Apr 22.


Autoinflammation behind the curtain.

Navarini AA, French LE.

Br J Dermatol. 2018 Mar;178(3):581-582. doi: 10.1111/bjd.16258. No abstract available.


Survival of Second-Line Biologics in Psoriasis: The British BADBIR Registry Data Informs Daily Practice.

Navarini AA, French LE.

J Invest Dermatol. 2018 Apr;138(4):726-728. doi: 10.1016/j.jid.2018.02.008.


Methadone-Not a magic bullet in melanoma therapy.

Brüggen MC, Mangana J, Irmisch A, French LE, Levesque MP, Cheng PF, Dummer R.

Exp Dermatol. 2018 Jun;27(6):694-696. doi: 10.1111/exd.13543.


The Crosstalk between Nrf2 and Inflammasomes.

Hennig P, Garstkiewicz M, Grossi S, Di Filippo M, French LE, Beer HD.

Int J Mol Sci. 2018 Feb 13;19(2). pii: E562. doi: 10.3390/ijms19020562. Review.


Propionibacterium acnes Strains Differentially Regulate the Fate of Th17 Responses in the Skin.

Contassot E, French LE.

J Invest Dermatol. 2018 Feb;138(2):251-253. doi: 10.1016/j.jid.2017.09.041.


Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes.

Sand J, Haertel E, Biedermann T, Contassot E, Reichmann E, French LE, Werner S, Beer HD.

Cell Death Dis. 2018 Jan 18;9(2):24. doi: 10.1038/s41419-017-0009-4.


TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.

Conrad C, Di Domizio J, Mylonas A, Belkhodja C, Demaria O, Navarini AA, Lapointe AK, French LE, Vernez M, Gilliet M.

Nat Commun. 2018 Jan 2;9(1):25. doi: 10.1038/s41467-017-02466-4.

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