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Items: 1 to 50 of 293

1.

Genome editing of human primary keratinocytes by CRISPR/Cas9 reveals an essential role of the NLRP1 inflammasome in UVB sensing.

Fenini G, Grossi S, Contassot E, Biedermann T, Reichmann E, French LE, Beer HD.

J Invest Dermatol. 2018 Aug 7. pii: S0022-202X(18)32462-X. doi: 10.1016/j.jid.2018.07.016. [Epub ahead of print]

PMID:
30096351
2.

Inflammation: A Contributor to Depressive Comorbidity in Inflammatory Skin Disease.

Farzanfar D, Dowlati Y, French LE, Lowes MA, Alavi A.

Skin Pharmacol Physiol. 2018 Jun 28;31(5):246-251. doi: 10.1159/000490002. [Epub ahead of print] Review.

3.

Cytokine Release Syndrome During Sequential Treatment With Immune Checkpoint Inhibitors and Kinase Inhibitors for Metastatic Melanoma.

Dimitriou F, Matter AV, Mangana J, Urosevic-Maiwald M, Micaletto S, Braun RP, French LE, Dummer R.

J Immunother. 2018 Jun 22. doi: 10.1097/CJI.0000000000000236. [Epub ahead of print]

PMID:
29939877
4.

PD-L1 expression is an independent predictor of favorable outcome in patients with localized esophageal adenocarcinoma.

Kollmann D, Ignatova D, Jedamzik J, Chang YT, Jomrich G, Baierl A, Kazakov D, Michal M, French LE, Hoetzenecker W, Schatton T, Asari R, Preusser M, Gnant M, Guenova E, Schoppmann SF.

Oncoimmunology. 2018 Mar 13;7(6):e1435226. doi: 10.1080/2162402X.2018.1435226. eCollection 2018.

PMID:
29872575
5.

Aggressive Rare T-cell Lymphomas with Manifestation in the Skin: A Monocentric Cross-sectional Case Study.

Brüggen MC, Kerl K, Haralambieva E, Schanz U, Chang YT, Ignatova D, Dummer R, Cozzio A, Hoetzenecker W, French LE, Guenova E.

Acta Derm Venereol. 2018 Apr 24. doi: 10.2340/00015555-2950. [Epub ahead of print]

6.

CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo.

Mellett M, Meier B, Mohanan D, Schairer R, Cheng P, Satoh TK, Kiefer B, Ospelt C, Nobbe S, Thome M, Contassot E, French LE.

J Invest Dermatol. 2018 Apr 22. pii: S0022-202X(18)31874-8. doi: 10.1016/j.jid.2018.03.1525. [Epub ahead of print]

7.

Autoinflammation behind the curtain.

Navarini AA, French LE.

Br J Dermatol. 2018 Mar;178(3):581-582. doi: 10.1111/bjd.16258. No abstract available.

PMID:
29595228
8.

Survival of Second-Line Biologics in Psoriasis: The British BADBIR Registry Data Informs Daily Practice.

Navarini AA, French LE.

J Invest Dermatol. 2018 Apr;138(4):726-728. doi: 10.1016/j.jid.2018.02.008.

PMID:
29579453
9.

Methadone-Not a magic bullet in melanoma therapy.

Brüggen MC, Mangana J, Irmisch A, French LE, Levesque MP, Cheng PF, Dummer R.

Exp Dermatol. 2018 Jun;27(6):694-696. doi: 10.1111/exd.13543.

PMID:
29577418
10.

The Crosstalk between Nrf2 and Inflammasomes.

Hennig P, Garstkiewicz M, Grossi S, Di Filippo M, French LE, Beer HD.

Int J Mol Sci. 2018 Feb 13;19(2). pii: E562. doi: 10.3390/ijms19020562. Review.

11.

Propionibacterium acnes Strains Differentially Regulate the Fate of Th17 Responses in the Skin.

Contassot E, French LE.

J Invest Dermatol. 2018 Feb;138(2):251-253. doi: 10.1016/j.jid.2017.09.041.

PMID:
29389326
12.

Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes.

Sand J, Haertel E, Biedermann T, Contassot E, Reichmann E, French LE, Werner S, Beer HD.

Cell Death Dis. 2018 Jan 18;9(2):24. doi: 10.1038/s41419-017-0009-4.

13.

TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.

Conrad C, Di Domizio J, Mylonas A, Belkhodja C, Demaria O, Navarini AA, Lapointe AK, French LE, Vernez M, Gilliet M.

Nat Commun. 2018 Jan 2;9(1):25. doi: 10.1038/s41467-017-02466-4.

14.

The p38 Mitogen-Activated Protein Kinase Critically Regulates Human Keratinocyte Inflammasome Activation.

Fenini G, Grossi S, Gehrke S, Beer HD, Satoh TK, Contassot E, French LE.

J Invest Dermatol. 2018 Jun;138(6):1380-1390. doi: 10.1016/j.jid.2017.10.037. Epub 2017 Dec 26.

PMID:
29287762
15.

Evaluation of the National Swiss Skin Cancer Screening Campaign 2013: Do We Do the Right Thing.

Braun RP, Ulrich K, Hunger R, Gaide O, Arnold A, Merat R, Dummer R, Hafner J, French LE, Cozzio A.

Dermatology. 2017;233(5):404-409. doi: 10.1159/000484946. Epub 2017 Dec 14.

16.

Radiotherapy-induced reactivation of neurotrophic human herpes viruses: Overview and management.

Ramirez-Fort MK, Zeng J, Feily A, Ramirez-Pacheco LA, Jenrette JM, Mayhew DL, Syed T, Cooper SL, Linden C, Graybill WS, French LE, Lange CS.

J Clin Virol. 2018 Jan;98:18-27. doi: 10.1016/j.jcv.2017.11.004. Epub 2017 Nov 22. Review.

PMID:
29197712
17.

Individualized treatment approaches for Langerhans cell histiocytosis.

Roider E, Signer C, Fehrenbacher B, Metzler G, Schaller M, Kamarachev J, Kerl K, Balabanov S, Jochum W, Hoetzenecker W, Cozzio A, French LE, Dummer R, Guenova E.

Br J Dermatol. 2018 Jun;178(6):1423-1424. doi: 10.1111/bjd.16171. Epub 2018 Mar 23. No abstract available.

PMID:
29194560
18.

Clinical Disease Patterns in a Regional Swiss Cohort of 34 Pyoderma Gangrenosum Patients.

Kolios AGA, Gübeli A, Meier B, Maul JT, Kündig T, Nilsson J, Hafner J, Guenova E, Kerl K, Anliker M, Kempf W, Navarini AA, French LE, Cozzio A.

Dermatology. 2017;233(4):268-276. doi: 10.1159/000481432. Epub 2017 Nov 7.

19.

Successful treatment of SAPHO syndrome with apremilast.

Adamo S, Nilsson J, Krebs A, Steiner U, Cozzio A, French LE, Kolios AGA.

Br J Dermatol. 2017 Oct 16. doi: 10.1111/bjd.16071. [Epub ahead of print]

PMID:
29034454
20.

TNFα and IL-17A are differentially expressed in psoriasis-like vs eczema-like drug reactions to TNFα antagonists.

Deubelbeiss C, Kolios AGA, Anzengruber F, French LE, Yawalkar N, Kempf W, Kerl K, Meier B, Navarini AA.

J Cutan Pathol. 2018 Jan;45(1):23-28. doi: 10.1111/cup.13055. Epub 2017 Nov 22.

PMID:
29023827
21.

Comparison of pyoderma gangrenosum and Martorell hypertensive ischaemic leg ulcer in a Swiss cohort.

Kolios AGA, Hafner J, Luder C, Guenova E, Kerl K, Kempf W, Nilsson J, French LE, Cozzio A.

Br J Dermatol. 2018 Feb;178(2):e125-e126. doi: 10.1111/bjd.15901. Epub 2018 Jan 7. No abstract available.

PMID:
28832960
22.

A case of tinea incognita and differential diagnosis of figurate erythema.

Maul JT, Maier PW, Anzengruber F, Murer C, Bosshard PP, Kerl K, French LE, Navarini AA.

Med Mycol Case Rep. 2017 Jul 3;18:8-11. doi: 10.1016/j.mmcr.2017.07.001. eCollection 2017 Dec.

23.

Drug-Induced Pyoderma Gangrenosum: A Review.

Wang JY, French LE, Shear NH, Amiri A, Alavi A.

Am J Clin Dermatol. 2018 Feb;19(1):67-77. doi: 10.1007/s40257-017-0308-7. Review.

PMID:
28624960
24.

Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration.

Kolios AGA, Cozzio A, Zinkernagel AS, French LE, Kündig TM.

Case Rep Dermatol. 2017 May 16;9(2):8-12. doi: 10.1159/000476054. eCollection 2017 May-Aug.

25.

Angioimmunoblastic T-Cell Lymphoma Mimicking Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS Syndrome).

Mangana J, Guenova E, Kerl K, Urosevic-Maiwald M, Amann VC, Bayard C, Dummer R, French LE.

Case Rep Dermatol. 2017 Mar 21;9(1):74-79. doi: 10.1159/000458752. eCollection 2017 Jan-Apr.

26.

Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.

Fenini G, Contassot E, French LE.

Front Pharmacol. 2017 May 22;8:278. doi: 10.3389/fphar.2017.00278. eCollection 2017. Review.

27.

Comparison of ixekizumab with ustekinumab in moderate-to-severe psoriasis: 24-week results from IXORA-S, a phase III study.

Reich K, Pinter A, Lacour JP, Ferrandiz C, Micali G, French LE, Lomaga M, Dutronc Y, Henneges C, Wilhelm S, Hartz S, Paul C; IXORA-S investigators.

Br J Dermatol. 2017 Oct;177(4):1014-1023. doi: 10.1111/bjd.15666. Epub 2017 Jul 19.

PMID:
28542874
28.

Paradoxical ulcerative colitis during adalimumab treatment of psoriasis resolved by switch to ustekinumab.

Kolios AGA, Biedermann L, Weber A, Navarini AA, Meier J, Cozzio A, French LE.

Br J Dermatol. 2018 Feb;178(2):551-555. doi: 10.1111/bjd.15631. Epub 2017 Nov 28.

PMID:
28477389
29.

Extreme Phenotype of Epidermal Growth Factor Receptor Inhibitor-induced Destructive Folliculitis.

Anzengruber F, Meier B, Maul JT, Kerl K, French LE, Navarini AA.

Int J Trichology. 2016 Oct-Dec;8(4):176-179. doi: 10.4103/0974-7753.203174.

30.

CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma.

Dziunycz PJ, Neu J, Lefort K, Djerbi N, Freiberger SN, Iotzova-Weiss G, French LE, Dotto GP, Hofbauer GF.

PLoS One. 2017 Apr 14;12(4):e0173000. doi: 10.1371/journal.pone.0173000. eCollection 2017.

31.

Successful treatment with imatinib after nilotinib and ipilimumab in a c-kit-mutated advanced melanoma patient: a case report.

Murer C, Kränzlin-Stieger P, French LE, Dummer R, Goldinger SM.

Melanoma Res. 2017 Aug;27(4):396-398. doi: 10.1097/CMR.0000000000000358.

PMID:
28410286
32.

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working Group.

Maverakis E, Wang EA, Shinkai K, Mahasirimongkol S, Margolis DJ, Avigan M, Chung WH, Goldman J, La Grenade L, Pirmohamed M, Shear NH, Tassaeeyakul W, Hoetzenecker W, Klaewsongkram J, Rerkpattanapipat T, Manuyakorn W, Yasuda SU, Sharon VR, Sukhov A, Micheletti R, Struewing J, French LE, Cheng MY.

JAMA Dermatol. 2017 Jun 1;153(6):587-592. doi: 10.1001/jamadermatol.2017.0160.

33.

Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression.

Garstkiewicz M, Strittmatter GE, Grossi S, Sand J, Fenini G, Werner S, French LE, Beer HD.

Eur J Immunol. 2017 May;47(5):806-817. doi: 10.1002/eji.201646665. Epub 2017 Apr 10.

34.

Pyoderma Gangrenosum: An Update on Pathophysiology, Diagnosis and Treatment.

Alavi A, French LE, Davis MD, Brassard A, Kirsner RS.

Am J Clin Dermatol. 2017 Jun;18(3):355-372. doi: 10.1007/s40257-017-0251-7. Review.

PMID:
28224502
35.

A Report of Two Cases of Solid Facial Edema in Acne.

Kuhn-Régnier S, Mangana J, Kerl K, Kamarachev J, French LE, Cozzio A, Navarini AA.

Dermatol Ther (Heidelb). 2017 Mar;7(1):167-174. doi: 10.1007/s13555-017-0173-6. Epub 2017 Feb 6.

36.

Superiority in Quality of Life Improvement of Biologics over Conventional Systemic Drugs in a Swiss Real-Life Psoriasis Registry.

Jungo P, Maul JT, Djamei V, von Felten S, Kolios AGA, Czernielewsk J, Yawalkar N, Odermatt O, Laffitte E, Anliker M, Streit M, Augustin M, Conrad C, Hafner J, Boehncke WH, Gilliet M, Itin P, French LE, Navarini AA, Häusermann P.

Dermatology. 2016;232(6):655-663. doi: 10.1159/000455042. Epub 2017 Jan 20.

37.

Efficacy and Survival of Systemic Psoriasis Treatments: An Analysis of the Swiss Registry SDNTT.

Maul JT, Djamei V, Kolios AGA, Meier B, Czernielewski J, Jungo P, Yawalkar N, Mainetti C, Laffitte E, Spehr C, Anliker M, Streit M, Augustin M, Rustenbach S, Conrad C, Hafner J, Boehncke WH, Borradori L, Gilliet M, Itin P, French LE, Häusermann P, Navarini AA.

Dermatology. 2016;232(6):640-647. doi: 10.1159/000452740. Epub 2017 Jan 12.

38.

Characterization of nivolumab-associated skin reactions in patients with metastatic non-small cell lung cancer.

Hasan Ali O, Diem S, Markert E, Jochum W, Kerl K, French LE, Speiser DE, Früh M, Flatz L.

Oncoimmunology. 2016 Sep 19;5(11):e1231292. doi: 10.1080/2162402X.2016.1231292. eCollection 2016.

39.

Worsening of Lymphopenia during Apremilast Treatment.

Kolios AG, French LE, Navarini AA.

Case Rep Dermatol. 2016 Nov 15;8(3):319-322. eCollection 2016 Sep-Dec.

40.

Mucocutaneous Ulcerations and Pancytopenia due to Methotrexate Overdose.

Knoll K, Anzengruber F, Cozzio A, French LE, Murer C, Navarini AA.

Case Rep Dermatol. 2016 Nov 7;8(3):287-293. eCollection 2016 Sep-Dec.

41.

Are neutrophilic dermatoses autoinflammatory disorders?

Satoh TK, Mellett M, Contassot E, French LE.

Br J Dermatol. 2018 Mar;178(3):603-613. doi: 10.1111/bjd.15105. Epub 2016 Nov 30. Review.

PMID:
27905098
42.

[Pyoderma gangrenosum and Sweet's syndrome : Cutaneous manifestations of autoinflammatory disorders].

Meier B, Maul JT, French LE.

Hautarzt. 2016 Dec;67(12):934-939. Review. German.

PMID:
27796411
43.

Impact of UVA on pruritus during UVA/B phototherapy of inflammatory skin diseases: a randomized double-blind study.

Maul JT, Kretschmer L, Anzengruber F, Pink A, Murer C, French LE, Hofbauer GF, Navarini AA.

J Eur Acad Dermatol Venereol. 2017 Jul;31(7):1208-1213. doi: 10.1111/jdv.13994. Epub 2016 Oct 25.

44.

European Guidelines (S1) on the use of high-dose intravenous immunoglobulin in dermatology.

Enk AH, Hadaschik EN, Eming R, Fierlbeck G, French LE, Girolomoni G, Hertl M, Jolles S, Karpati S, Steinbrink K, Stingl G, Volc-Platzer B, Zillikens D.

J Eur Acad Dermatol Venereol. 2016 Oct;30(10):1657-1669. doi: 10.1111/jdv.13725. Epub 2016 Jul 13.

45.

Apremilast Is Effective in Lichen Planus Mucosae-Associated Stenotic Esophagitis.

Hafner J, Gubler C, Kaufmann K, Nobbe S, Navarini AA, French LE.

Case Rep Dermatol. 2016 Aug 29;8(2):224-226. eCollection 2016 May-Aug.

46.

In Situ Mapping of Innate Lymphoid Cells in Human Skin: Evidence for Remarkable Differences between Normal and Inflamed Skin.

Brüggen MC, Bauer WM, Reininger B, Clim E, Captarencu C, Steiner GE, Brunner PM, Meier B, French LE, Stingl G.

J Invest Dermatol. 2016 Dec;136(12):2396-2405. doi: 10.1016/j.jid.2016.07.017. Epub 2016 Jul 22.

47.

Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages.

Huber R, Meier B, Otsuka A, Fenini G, Satoh T, Gehrke S, Widmer D, Levesque MP, Mangana J, Kerl K, Gebhardt C, Fujii H, Nakashima C, Nonomura Y, Kabashima K, Dummer R, Contassot E, French LE.

Sci Rep. 2016 Jul 18;6:29914. doi: 10.1038/srep29914.

48.

Swiss S1 Guidelines on the Systemic Treatment of Psoriasis Vulgaris.

Kolios AG, Yawalkar N, Anliker M, Boehncke WH, Borradori L, Conrad C, Gilliet M, Häusermann P, Itin P, Laffitte E, Mainetti C, French LE, Navarini AA.

Dermatology. 2016;232(4):385-406. doi: 10.1159/000445681. Epub 2016 Jun 21.

49.

Toxic epidermal necrolysis.

Hoetzenecker W, Mehra T, Saulite I, Glatz M, Schmid-Grendelmeier P, Guenova E, Cozzio A, French LE.

F1000Res. 2016 May 20;5. pii: F1000 Faculty Rev-951. doi: 10.12688/f1000research.7574.1. eCollection 2016. Review.

50.

Transient Efficacy of Tofacitinib in Alopecia Areata Universalis.

Anzengruber F, Maul JT, Kamarachev J, Trüeb RM, French LE, Navarini AA.

Case Rep Dermatol. 2016 Apr 22;8(1):102-6. doi: 10.1159/000445182. eCollection 2016 Jan-Apr.

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