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A new link between autoinflammation and hidradenitis suppurativa?

Contassot E, French LE.

Br J Dermatol. 2019 Jun;180(6):1294-1295. doi: 10.1111/bjd.17908. No abstract available.


Design of in vitro Transcribed mRNA Vectors for Research and Therapy.

Tusup M, French LE, De Matos M, Gatfield D, Kundig T, Pascolo S.

Chimia (Aarau). 2019 May 29;73(6):391-394. doi: 10.2533/chimia.2019.391. Review.


Smoking does not Alter the Therapy Response to Systemic Anti-psoriatic Therapies: A Two-country, Multi-centre, Prospective, Non-interventional Study.

Anzengruber F, Augustin M, Radtke MA, Thaci D, Yawalkar N, Streit M, Reich K, Drach M, Sorbe C, French LE, Mrowietz U, Maul JT, Itin PH, Navarini AA.

Acta Derm Venereol. 2019 May 17. doi: 10.2340/00015555-3221. [Epub ahead of print]


Subcutaneous white adipose tissue of healthy young individuals harbors a leukocyte compartment distinct from skin and blood.

Brüggen MC, Strobl J, Koszik F, Naito R, Vierhapper M, Li N, Stary G, Kiprov H, French LE, Stingl G.

J Invest Dermatol. 2019 Apr 8. pii: S0022-202X(19)31453-8. doi: 10.1016/j.jid.2019.02.034. [Epub ahead of print] No abstract available.


Nickel contact dermatitis evaluated by means of optical coherence tomography: first impressions.

Ruini C, Wittmann D, Summer B, von Braunmühl T, French LE, Thomas P.

J Eur Acad Dermatol Venereol. 2019 Feb 28. doi: 10.1111/jdv.15536. [Epub ahead of print] No abstract available.


The NLRP1 Inflammasome Pathway Is Silenced in Cutaneous Squamous Cell Carcinoma.

Sand J, Fenini G, Grossi S, Hennig P, Di Filippo M, Levesque M, Werner S, French LE, Beer HD.

J Invest Dermatol. 2019 Feb 7. pii: S0022-202X(19)30105-8. doi: 10.1016/j.jid.2019.01.025. [Epub ahead of print]


Divergent LAG-3 versus BTLA, TIGIT, and FCRL3 expression in Sézary syndrome.

Anzengruber F, Ignatova D, Schlaepfer T, Chang YT, French LE, Pascolo S, Contassot E, Bobrowicz M, Hoetzenecker W, Guenova E.

Leuk Lymphoma. 2019 Jan 14:1-9. doi: 10.1080/10428194.2018.1564827. [Epub ahead of print]


Thermography: High sensitivity and specificity diagnosing contact dermatitis in patch testing.

Anzengruber F, Alotaibi F, Kaufmann LS, Ghosh A, Oswald MR, Maul JT, Meier B, French LE, Bonmarin M, Navarini AA.

Allergol Int. 2019 Apr;68(2):254-258. doi: 10.1016/j.alit.2018.12.001. Epub 2018 Dec 29.


Interferon alfa-2a maintenance after salvage autologous stem cell transplantation in atypical mycosis fungoides with central nervous system involvement.

Doerschner M, Pekar-Lukacs A, Messerli-Odermatt O, Dommann-Scherrer C, Rütti M, Müller AM, Nair G, Kamarachev J, Kerl K, Beer M, Messerli M, Frauenknecht K, Haralambieva E, Hoetzenecker W, French LE, Guenova E.

Br J Dermatol. 2018 Dec 18. doi: 10.1111/bjd.17535. [Epub ahead of print]


Culprit Drugs Induce Specific IL-36 Overexpression in Acute Generalized Exanthematous Pustulosis.

Meier-Schiesser B, Feldmeyer L, Jankovic D, Mellett M, Satoh TK, Yerly D, Navarini A, Abe R, Yawalkar N, Chung WH, French LE, Contassot E.

J Invest Dermatol. 2019 Apr;139(4):848-858. doi: 10.1016/j.jid.2018.10.023. Epub 2018 Nov 2.


Gender and age significantly determine patient needs and treatment goals in psoriasis - a lesson for practice.

Maul JT, Navarini AA, Sommer R, Anzengruber F, Sorbe C, Mrowietz U, Drach M, Blome C, Boehncke WH, Thaci D, Reich K, von Kiedrowski R, Körber A, Yawalkar N, Mainetti C, Laffitte E, Streit M, Rustenbach S, Conrad C, Borradori L, Gilliet M, Cozzio A, Itin P, Häusermann P, French LE, Radtke MA, Augustin M.

J Eur Acad Dermatol Venereol. 2019 Apr;33(4):700-708. doi: 10.1111/jdv.15324. Epub 2019 Jan 15.


Teledermatology: Comparison of Store-and-Forward Versus Live Interactive Video Conferencing.

Brinker TJ, Hekler A, von Kalle C, Schadendorf D, Esser S, Berking C, Zacher MT, Sondermann W, Grabe N, Steeb T, Utikal JS, French LE, Enk AH.

J Med Internet Res. 2018 Oct 24;20(10):e11871. doi: 10.2196/11871.


[Painful lymphadenopathy after an insect bite-a case report].

Vukovic S, Anagnostopoulos A, Zbinden R, Schönenberger L, Guillod C, French LE, Navarini A, Roider E.

Hautarzt. 2019 Jan;70(1):47-50. doi: 10.1007/s00105-018-4237-z. German.


Topical resiquimod dosing regimens in patients with multiple actinic keratoses: a multicentre, partly placebo-controlled, double-blind clinical trial.

Stockfleth E, Hofbauer GFL, Reinhold U, Popp G, Hengge UR, Szeimies RM, Brüning H, Anliker M, Hunger T, Dummer R, Ulrich C, Kenzelmann R, Surber C, French LE.

Br J Dermatol. 2019 Feb;180(2):297-305. doi: 10.1111/bjd.17124. Epub 2018 Oct 22.


Mechanisms Underlying the Clinical Effects of Apremilast for Psoriasis.

Pincelli C, Schafer PH, French LE, Augustin M, Krueger JG.

J Drugs Dermatol. 2018 Aug 1;17(8):835-840. Review.


Genome Editing of Human Primary Keratinocytes by CRISPR/Cas9 Reveals an Essential Role of the NLRP1 Inflammasome in UVB Sensing.

Fenini G, Grossi S, Contassot E, Biedermann T, Reichmann E, French LE, Beer HD.

J Invest Dermatol. 2018 Dec;138(12):2644-2652. doi: 10.1016/j.jid.2018.07.016. Epub 2018 Aug 7.


Inflammation: A Contributor to Depressive Comorbidity in Inflammatory Skin Disease.

Farzanfar D, Dowlati Y, French LE, Lowes MA, Alavi A.

Skin Pharmacol Physiol. 2018;31(5):246-251. doi: 10.1159/000490002. Epub 2018 Jun 28. Review.


Cytokine Release Syndrome During Sequential Treatment With Immune Checkpoint Inhibitors and Kinase Inhibitors for Metastatic Melanoma.

Dimitriou F, Matter AV, Mangana J, Urosevic-Maiwald M, Micaletto S, Braun RP, French LE, Dummer R.

J Immunother. 2019 Jan;42(1):29-32. doi: 10.1097/CJI.0000000000000236.


PD-L1 expression is an independent predictor of favorable outcome in patients with localized esophageal adenocarcinoma.

Kollmann D, Ignatova D, Jedamzik J, Chang YT, Jomrich G, Baierl A, Kazakov D, Michal M, French LE, Hoetzenecker W, Schatton T, Asari R, Preusser M, Gnant M, Guenova E, Schoppmann SF.

Oncoimmunology. 2018 Mar 13;7(6):e1435226. doi: 10.1080/2162402X.2018.1435226. eCollection 2018.


Aggressive Rare T-cell Lymphomas with Manifestation in the Skin: A Monocentric Cross-sectional Case Study.

Brüggen MC, Kerl K, Haralambieva E, Schanz U, Chang YT, Ignatova D, Dummer R, Cozzio A, Hoetzenecker W, French LE, Guenova E.

Acta Derm Venereol. 2018 Oct 10;98(9):835-841. doi: 10.2340/00015555-2950.


CARD14 Gain-of-Function Mutation Alone Is Sufficient to Drive IL-23/IL-17-Mediated Psoriasiform Skin Inflammation In Vivo.

Mellett M, Meier B, Mohanan D, Schairer R, Cheng P, Satoh TK, Kiefer B, Ospelt C, Nobbe S, Thome M, Contassot E, French LE.

J Invest Dermatol. 2018 Sep;138(9):2010-2023. doi: 10.1016/j.jid.2018.03.1525. Epub 2018 Apr 22.


Autoinflammation behind the curtain.

Navarini AA, French LE.

Br J Dermatol. 2018 Mar;178(3):581-582. doi: 10.1111/bjd.16258. No abstract available.


Survival of Second-Line Biologics in Psoriasis: The British BADBIR Registry Data Informs Daily Practice.

Navarini AA, French LE.

J Invest Dermatol. 2018 Apr;138(4):726-728. doi: 10.1016/j.jid.2018.02.008.


Methadone-Not a magic bullet in melanoma therapy.

Brüggen MC, Mangana J, Irmisch A, French LE, Levesque MP, Cheng PF, Dummer R.

Exp Dermatol. 2018 Jun;27(6):694-696. doi: 10.1111/exd.13543.


The Crosstalk between Nrf2 and Inflammasomes.

Hennig P, Garstkiewicz M, Grossi S, Di Filippo M, French LE, Beer HD.

Int J Mol Sci. 2018 Feb 13;19(2). pii: E562. doi: 10.3390/ijms19020562. Review.


Propionibacterium acnes Strains Differentially Regulate the Fate of Th17 Responses in the Skin.

Contassot E, French LE.

J Invest Dermatol. 2018 Feb;138(2):251-253. doi: 10.1016/j.jid.2017.09.041.


Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes.

Sand J, Haertel E, Biedermann T, Contassot E, Reichmann E, French LE, Werner S, Beer HD.

Cell Death Dis. 2018 Jan 18;9(2):24. doi: 10.1038/s41419-017-0009-4.


TNF blockade induces a dysregulated type I interferon response without autoimmunity in paradoxical psoriasis.

Conrad C, Di Domizio J, Mylonas A, Belkhodja C, Demaria O, Navarini AA, Lapointe AK, French LE, Vernez M, Gilliet M.

Nat Commun. 2018 Jan 2;9(1):25. doi: 10.1038/s41467-017-02466-4.


The p38 Mitogen-Activated Protein Kinase Critically Regulates Human Keratinocyte Inflammasome Activation.

Fenini G, Grossi S, Gehrke S, Beer HD, Satoh TK, Contassot E, French LE.

J Invest Dermatol. 2018 Jun;138(6):1380-1390. doi: 10.1016/j.jid.2017.10.037. Epub 2017 Dec 26.


Evaluation of the National Swiss Skin Cancer Screening Campaign 2013: Do We Do the Right Thing.

Braun RP, Ulrich K, Hunger R, Gaide O, Arnold A, Merat R, Dummer R, Hafner J, French LE, Cozzio A.

Dermatology. 2017;233(5):404-409. doi: 10.1159/000484946. Epub 2017 Dec 14.


Radiotherapy-induced reactivation of neurotrophic human herpes viruses: Overview and management.

Ramirez-Fort MK, Zeng J, Feily A, Ramirez-Pacheco LA, Jenrette JM, Mayhew DL, Syed T, Cooper SL, Linden C, Graybill WS, French LE, Lange CS.

J Clin Virol. 2018 Jan;98:18-27. doi: 10.1016/j.jcv.2017.11.004. Epub 2017 Nov 22. Review.


Individualized treatment approaches for Langerhans cell histiocytosis.

Roider E, Signer C, Fehrenbacher B, Metzler G, Schaller M, Kamarachev J, Kerl K, Balabanov S, Jochum W, Hoetzenecker W, Cozzio A, French LE, Dummer R, Guenova E.

Br J Dermatol. 2018 Jun;178(6):1423-1424. doi: 10.1111/bjd.16171. Epub 2018 Mar 23. No abstract available.


Clinical Disease Patterns in a Regional Swiss Cohort of 34 Pyoderma Gangrenosum Patients.

Kolios AGA, Gübeli A, Meier B, Maul JT, Kündig T, Nilsson J, Hafner J, Guenova E, Kerl K, Anliker M, Kempf W, Navarini AA, French LE, Cozzio A.

Dermatology. 2017;233(4):268-276. doi: 10.1159/000481432. Epub 2017 Nov 7.


Successful treatment of SAPHO syndrome with apremilast.

Adamo S, Nilsson J, Krebs A, Steiner U, Cozzio A, French LE, Kolios AGA.

Br J Dermatol. 2018 Oct;179(4):959-962. doi: 10.1111/bjd.16071. Epub 2018 Mar 14.


TNFα and IL-17A are differentially expressed in psoriasis-like vs eczema-like drug reactions to TNFα antagonists.

Deubelbeiss C, Kolios AGA, Anzengruber F, French LE, Yawalkar N, Kempf W, Kerl K, Meier B, Navarini AA.

J Cutan Pathol. 2018 Jan;45(1):23-28. doi: 10.1111/cup.13055. Epub 2017 Nov 22.


Comparison of pyoderma gangrenosum and Martorell hypertensive ischaemic leg ulcer in a Swiss cohort.

Kolios AGA, Hafner J, Luder C, Guenova E, Kerl K, Kempf W, Nilsson J, French LE, Cozzio A.

Br J Dermatol. 2018 Feb;178(2):e125-e126. doi: 10.1111/bjd.15901. Epub 2018 Jan 7. No abstract available.


A case of tinea incognita and differential diagnosis of figurate erythema.

Maul JT, Maier PW, Anzengruber F, Murer C, Bosshard PP, Kerl K, French LE, Navarini AA.

Med Mycol Case Rep. 2017 Jul 3;18:8-11. doi: 10.1016/j.mmcr.2017.07.001. eCollection 2017 Dec.


Drug-Induced Pyoderma Gangrenosum: A Review.

Wang JY, French LE, Shear NH, Amiri A, Alavi A.

Am J Clin Dermatol. 2018 Feb;19(1):67-77. doi: 10.1007/s40257-017-0308-7. Review.


Cutaneous Corynebacterium Infection Presenting with Disseminated Skin Nodules and Ulceration.

Kolios AGA, Cozzio A, Zinkernagel AS, French LE, Kündig TM.

Case Rep Dermatol. 2017 May 16;9(2):8-12. doi: 10.1159/000476054. eCollection 2017 May-Aug.


Angioimmunoblastic T-Cell Lymphoma Mimicking Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS Syndrome).

Mangana J, Guenova E, Kerl K, Urosevic-Maiwald M, Amann VC, Bayard C, Dummer R, French LE.

Case Rep Dermatol. 2017 Mar 21;9(1):74-79. doi: 10.1159/000458752. eCollection 2017 Jan-Apr.


Potential of IL-1, IL-18 and Inflammasome Inhibition for the Treatment of Inflammatory Skin Diseases.

Fenini G, Contassot E, French LE.

Front Pharmacol. 2017 May 22;8:278. doi: 10.3389/fphar.2017.00278. eCollection 2017. Review.


Comparison of ixekizumab with ustekinumab in moderate-to-severe psoriasis: 24-week results from IXORA-S, a phase III study.

Reich K, Pinter A, Lacour JP, Ferrandiz C, Micali G, French LE, Lomaga M, Dutronc Y, Henneges C, Wilhelm S, Hartz S, Paul C; IXORA-S investigators.

Br J Dermatol. 2017 Oct;177(4):1014-1023. doi: 10.1111/bjd.15666. Epub 2017 Jul 19.


Paradoxical ulcerative colitis during adalimumab treatment of psoriasis resolved by switch to ustekinumab.

Kolios AGA, Biedermann L, Weber A, Navarini AA, Meier J, Cozzio A, French LE.

Br J Dermatol. 2018 Feb;178(2):551-555. doi: 10.1111/bjd.15631. Epub 2017 Nov 28.


Extreme Phenotype of Epidermal Growth Factor Receptor Inhibitor-induced Destructive Folliculitis.

Anzengruber F, Meier B, Maul JT, Kerl K, French LE, Navarini AA.

Int J Trichology. 2016 Oct-Dec;8(4):176-179. doi: 10.4103/0974-7753.203174.


CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma.

Dziunycz PJ, Neu J, Lefort K, Djerbi N, Freiberger SN, Iotzova-Weiss G, French LE, Dotto GP, Hofbauer GF.

PLoS One. 2017 Apr 14;12(4):e0173000. doi: 10.1371/journal.pone.0173000. eCollection 2017.


Successful treatment with imatinib after nilotinib and ipilimumab in a c-kit-mutated advanced melanoma patient: a case report.

Murer C, Kränzlin-Stieger P, French LE, Dummer R, Goldinger SM.

Melanoma Res. 2017 Aug;27(4):396-398. doi: 10.1097/CMR.0000000000000358.


Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working Group.

Maverakis E, Wang EA, Shinkai K, Mahasirimongkol S, Margolis DJ, Avigan M, Chung WH, Goldman J, La Grenade L, Pirmohamed M, Shear NH, Tassaeeyakul W, Hoetzenecker W, Klaewsongkram J, Rerkpattanapipat T, Manuyakorn W, Yasuda SU, Sharon VR, Sukhov A, Micheletti R, Struewing J, French LE, Cheng MY.

JAMA Dermatol. 2017 Jun 1;153(6):587-592. doi: 10.1001/jamadermatol.2017.0160. Erratum in: JAMA Dermatol. 2017 Jun 1;153(6):613. JAMA Dermatol. 2017 Aug 1;153(8):837.


Opposing effects of Nrf2 and Nrf2-activating compounds on the NLRP3 inflammasome independent of Nrf2-mediated gene expression.

Garstkiewicz M, Strittmatter GE, Grossi S, Sand J, Fenini G, Werner S, French LE, Beer HD.

Eur J Immunol. 2017 May;47(5):806-817. doi: 10.1002/eji.201646665. Epub 2017 Apr 10.


Pyoderma Gangrenosum: An Update on Pathophysiology, Diagnosis and Treatment.

Alavi A, French LE, Davis MD, Brassard A, Kirsner RS.

Am J Clin Dermatol. 2017 Jun;18(3):355-372. doi: 10.1007/s40257-017-0251-7. Review.


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