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Items: 16

1.

Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase.

Fitzpatrick LR, Green C, Frauenhoffer EE, French KJ, Zhuang Y, Maines LW, Upson JJ, Paul E, Donahue H, Mosher TJ, Smith CD.

Inflammopharmacology. 2011 Apr;19(2):75-87. doi: 10.1007/s10787-010-0060-6. Epub 2010 Oct 11.

PMID:
20936538
2.

Differences in effects on myocardium and mitochondria by angiogenic inhibitors suggest separate mechanisms of cardiotoxicity.

French KJ, Coatney RW, Renninger JP, Hu CX, Gales TL, Zhao S, Storck LM, Davis CB, McSurdy-Freed J, Chen E, Frazier KS.

Toxicol Pathol. 2010 Aug;38(5):691-702. doi: 10.1177/0192623310373775. Epub 2010 Jul 8.

PMID:
20616376
3.

Pharmacology and antitumor activity of ABC294640, a selective inhibitor of sphingosine kinase-2.

French KJ, Zhuang Y, Maines LW, Gao P, Wang W, Beljanski V, Upson JJ, Green CL, Keller SN, Smith CD.

J Pharmacol Exp Ther. 2010 Apr;333(1):129-39. doi: 10.1124/jpet.109.163444. Epub 2010 Jan 8.

4.

Suppression of ulcerative colitis in mice by orally available inhibitors of sphingosine kinase.

Maines LW, Fitzpatrick LR, French KJ, Zhuang Y, Xia Z, Keller SN, Upson JJ, Smith CD.

Dig Dis Sci. 2008 Apr;53(4):997-1012. Epub 2007 Dec 4.

5.

Pharmacologic manipulation of sphingosine kinase in retinal endothelial cells: implications for angiogenic ocular diseases.

Maines LW, French KJ, Wolpert EB, Antonetti DA, Smith CD.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):5022-31.

6.

Antitumor activity of sphingosine kinase inhibitors.

French KJ, Upson JJ, Keller SN, Zhuang Y, Yun JK, Smith CD.

J Pharmacol Exp Ther. 2006 Aug;318(2):596-603. Epub 2006 Apr 21.

PMID:
16632640
7.
8.

Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase.

Ducker CE, Stettler EM, French KJ, Upson JJ, Smith CD.

Oncogene. 2004 Dec 9;23(57):9230-7.

9.

Synthesis and evaluation of dihydropyrroloquinolines that selectively antagonize P-glycoprotein.

Lee BD, Li Z, French KJ, Zhuang Y, Xia Z, Smith CD.

J Med Chem. 2004 Mar 11;47(6):1413-22.

PMID:
14998330
10.

Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-based inhibitors of human N-myristoyltransferase-1.

French KJ, Zhuang Y, Schrecengost RS, Copper JE, Xia Z, Smith CD.

J Pharmacol Exp Ther. 2004 Apr;309(1):340-7. Epub 2004 Jan 14.

PMID:
14724220
11.
12.

Discovery and evaluation of inhibitors of human sphingosine kinase.

French KJ, Schrecengost RS, Lee BD, Zhuang Y, Smith SN, Eberly JL, Yun JK, Smith CD.

Cancer Res. 2003 Sep 15;63(18):5962-9.

13.

Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol.

French KJ, Rock DA, Rock DA, Manchester JI, Goldstein BM, Jones JP.

Arch Biochem Biophys. 2002 Feb 15;398(2):188-97.

PMID:
11831849
14.

Benign synthesis of 2-ethylhexanoic acid by cytochrome P450cam: enzymatic, crystallographic, and theoretical studies.

French KJ, Strickler MD, Rock DA, Rock DA, Bennett GA, Wahlstrom JL, Goldstein BM, Jones JP.

Biochemistry. 2001 Aug 14;40(32):9532-8.

PMID:
11583152
15.

Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway.

Zhang Q, Peyruchaud O, French KJ, Magnusson MK, Mosher DF.

Blood. 1999 May 1;93(9):2984-90.

PMID:
10216094
16.

Use of computed radiography in the study of an historic painting.

Reiner BI, Siegel EL, French KJ, Dentry RS, Mazan WT, Maroney MJ.

Radiographics. 1997 Nov-Dec;17(6):1487-95.

PMID:
9397460

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