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Hurricane Impact on Emergency Services and Use of Telehealth to Support Prehospital Care.

French DM, Hall GA, McGeorge T, Haschker M, Brazeal JG, Dubose-Morris R.

Disaster Med Public Health Prep. 2019 Oct 23:1-5. doi: 10.1017/dmp.2019.101. [Epub ahead of print]


Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain.

Newton K, Dugger DL, Sengupta-Ghosh A, Ferrando RE, Chu F, Tao J, Lam W, Haller S, Chan S, Sa S, Dunlap D, Eastham-Anderson J, Ngu H, Hung J, French DM, Webster JD, Bolon B, Liu J, Reja R, Kummerfeld S, Chen YJ, Modrusan Z, Lewcock JW, Dixit VM.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11244-11249. doi: 10.1073/pnas.1805033115. Epub 2018 Oct 15.


ASK1 contributes to fibrosis and dysfunction in models of kidney disease.

Liles JT, Corkey BK, Notte GT, Budas GR, Lansdon EB, Hinojosa-Kirschenbaum F, Badal SS, Lee M, Schultz BE, Wise S, Pendem S, Graupe M, Castonguay L, Koch KA, Wong MH, Papalia GA, French DM, Sullivan T, Huntzicker EG, Ma FY, Nikolic-Paterson DJ, Altuhaifi T, Yang H, Fogo AB, Breckenridge DG.

J Clin Invest. 2018 Oct 1;128(10):4485-4500. doi: 10.1172/JCI99768. Epub 2018 Jul 19.


Public CPR and AED Knowledge: An Opportunity for Educational Outreach in South Carolina.

Petruncio LM, French DM, Jauch EC.

South Med J. 2018 Jun;111(6):349-352. doi: 10.14423/SMJ.0000000000000818.


Myasthenic Crisis In Pregnancy.

French DM, Bridges EP, Hoskins MC, Andrews CM, Nelson CH.

Clin Pract Cases Emerg Med. 2017 Oct 3;1(4):291-294. doi: 10.5811/cpcem.2017.5.33404. eCollection 2017 Nov.


Anti-HBV response to toll-like receptor 7 agonist GS-9620 is associated with intrahepatic aggregates of T cells and B cells.

Li L, Barry V, Daffis S, Niu C, Huntzicker E, French DM, Mikaelian I, Lanford RE, Delaney WE 4th, Fletcher SP.

J Hepatol. 2018 May;68(5):912-921. doi: 10.1016/j.jhep.2017.12.008. Epub 2017 Dec 14.


High power microwave source with a three dimensional printed metamaterial slow-wave structure.

French DM, Shiffler D.

Rev Sci Instrum. 2016 May;87(5):053308. doi: 10.1063/1.4950904.


Apparatus for generating quasi-free-space microwave-driven plasmas.

Hoff BW, French DM, Reid RR, Lawrance JE, Lepell PD, Maestas SS.

Rev Sci Instrum. 2016 Mar;87(3):033507. doi: 10.1063/1.4944865.


Immunohistochemical detection of FLAG-tagged endogenous proteins in knock-in mice.

Ferrando RE, Newton K, Chu F, Webster JD, French DM.

J Histochem Cytochem. 2015 Apr;63(4):244-55. doi: 10.1369/0022155414568101. Epub 2015 Jan 9.


Differential effects of targeting Notch receptors in a mouse model of liver cancer.

Huntzicker EG, Hötzel K, Choy L, Che L, Ross J, Pau G, Sharma N, Siebel CW, Chen X, French DM.

Hepatology. 2015 Mar;61(3):942-52. doi: 10.1002/hep.27566. Epub 2015 Jan 28.


An antimesothelin-monomethyl auristatin e conjugate with potent antitumor activity in ovarian, pancreatic, and mesothelioma models.

Scales SJ, Gupta N, Pacheco G, Firestein R, French DM, Koeppen H, Rangell L, Barry-Hamilton V, Luis E, Chuh J, Zhang Y, Ingle GS, Fourie-O'Donohue A, Kozak KR, Ross S, Dennis MS, Spencer SD.

Mol Cancer Ther. 2014 Nov;13(11):2630-40. doi: 10.1158/1535-7163.MCT-14-0487-T. Epub 2014 Sep 23.


Diverse modes of genomic alteration in hepatocellular carcinoma.

Jhunjhunwala S, Jiang Z, Stawiski EW, Gnad F, Liu J, Mayba O, Du P, Diao J, Johnson S, Wong KF, Gao Z, Li Y, Wu TD, Kapadia SB, Modrusan Z, French DM, Luk JM, Seshagiri S, Zhang Z.

Genome Biol. 2014 Aug 26;15(8):436. doi: 10.1186/s13059-014-0436-9.


Ambulance diversion by cooperation: a positive experience with a physician-directed ambulance diversion policy in Charleston County, South Carolina.

Shealy RM, Sorrell JF, French DM.

Ann Emerg Med. 2014 Jul;64(1):97-8. doi: 10.1016/j.annemergmed.2014.03.021. No abstract available.


Activity of protein kinase RIPK3 determines whether cells die by necroptosis or apoptosis.

Newton K, Dugger DL, Wickliffe KE, Kapoor N, de Almagro MC, Vucic D, Komuves L, Ferrando RE, French DM, Webster J, Roose-Girma M, Warming S, Dixit VM.

Science. 2014 Mar 21;343(6177):1357-60. doi: 10.1126/science.1249361. Epub 2014 Feb 20.


Nonlinear transmission line based electron beam driver.

French DM, Hoff BW, Tang W, Heidger S, Allen-Flowers J, Shiffler D.

Rev Sci Instrum. 2012 Dec;83(12):123302. doi: 10.1063/1.4770331.


Loss of the tumor suppressor BAP1 causes myeloid transformation.

Dey A, Seshasayee D, Noubade R, French DM, Liu J, Chaurushiya MS, Kirkpatrick DS, Pham VC, Lill JR, Bakalarski CE, Wu J, Phu L, Katavolos P, LaFave LM, Abdel-Wahab O, Modrusan Z, Seshagiri S, Dong K, Lin Z, Balazs M, Suriben R, Newton K, Hymowitz S, Garcia-Manero G, Martin F, Levine RL, Dixit VM.

Science. 2012 Sep 21;337(6101):1541-6. Epub 2012 Aug 9.


Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models.

French DM, Lin BC, Wang M, Adams C, Shek T, Hötzel K, Bolon B, Ferrando R, Blackmore C, Schroeder K, Rodriguez LA, Hristopoulos M, Venook R, Ashkenazi A, Desnoyers LR.

PLoS One. 2012;7(5):e36713. doi: 10.1371/journal.pone.0036713. Epub 2012 May 15.


USP1 deubiquitinates ID proteins to preserve a mesenchymal stem cell program in osteosarcoma.

Williams SA, Maecker HL, French DM, Liu J, Gregg A, Silverstein LB, Cao TC, Carano RA, Dixit VM.

Cell. 2011 Sep 16;146(6):918-30. doi: 10.1016/j.cell.2011.07.040.


COP1 is a tumour suppressor that causes degradation of ETS transcription factors.

Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM.

Nature. 2011 May 15;474(7351):403-6. doi: 10.1038/nature10005.


FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.

Wu AL, Coulter S, Liddle C, Wong A, Eastham-Anderson J, French DM, Peterson AS, Sonoda J.

PLoS One. 2011 Mar 18;6(3):e17868. doi: 10.1371/journal.pone.0017868.


Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening.

Sawey ET, Chanrion M, Cai C, Wu G, Zhang J, Zender L, Zhao A, Busuttil RW, Yee H, Stein L, French DM, Finn RS, Lowe SW, Powers S.

Cancer Cell. 2011 Mar 8;19(3):347-58. doi: 10.1016/j.ccr.2011.01.040.


Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

Pereg Y, Liu BY, O'Rourke KM, Sagolla M, Dey A, Komuves L, French DM, Dixit VM.

Nat Cell Biol. 2010 Apr;12(4):400-6. doi: 10.1038/ncb2041. Epub 2010 Mar 14.


Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.

Schwickart M, Huang X, Lill JR, Liu J, Ferrando R, French DM, Maecker H, O'Rourke K, Bazan F, Eastham-Anderson J, Yue P, Dornan D, Huang DC, Dixit VM.

Nature. 2010 Jan 7;463(7277):103-7. doi: 10.1038/nature08646. Epub 2009 Dec 20.


Viable tumor tissue detection in murine metastatic breast cancer by whole-body MRI and multispectral analysis.

Barck KH, Willis B, Ross J, French DM, Filvaroff EH, Carano RA.

Magn Reson Med. 2009 Dec;62(6):1423-30. doi: 10.1002/mrm.22109.


TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling.

Junge HJ, Yang S, Burton JB, Paes K, Shu X, French DM, Costa M, Rice DS, Ye W.

Cell. 2009 Oct 16;139(2):299-311. doi: 10.1016/j.cell.2009.07.048.


Microwave window breakdown experiments and simulations on the UM/L-3 relativistic magnetron.

Hoff BW, Mardahl PJ, Gilgenbach RM, Haworth MD, French DM, Lau YY, Franzi M.

Rev Sci Instrum. 2009 Sep;80(9):094702. doi: 10.1063/1.3233917.


Effect of soft metal gasket contacts on contact resistance, energy deposition, and plasma expansion profile in a wire array Z pinch.

Gomez MR, Zier JC, Gilgenbach RM, French DM, Tang W, Lau YY.

Rev Sci Instrum. 2008 Sep;79(9):093512. doi: 10.1063/1.2991110.


Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.

Newton K, Matsumoto ML, Wertz IE, Kirkpatrick DS, Lill JR, Tan J, Dugger D, Gordon N, Sidhu SS, Fellouse FA, Komuves L, French DM, Ferrando RE, Lam C, Compaan D, Yu C, Bosanac I, Hymowitz SG, Kelley RF, Dixit VM.

Cell. 2008 Aug 22;134(4):668-78. doi: 10.1016/j.cell.2008.07.039.


Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling.

Pai R, Dunlap D, Qing J, Mohtashemi I, Hotzel K, French DM.

Cancer Res. 2008 Jul 1;68(13):5086-95. doi: 10.1158/0008-5472.CAN-07-2325.


Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.

Desnoyers LR, Pai R, Ferrando RE, Hötzel K, Le T, Ross J, Carano R, D'Souza A, Qing J, Mohtashemi I, Ashkenazi A, French DM.

Oncogene. 2008 Jan 3;27(1):85-97. Epub 2007 Jun 25.


Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.

Holst CR, Bou-Reslan H, Gore BB, Wong K, Grant D, Chalasani S, Carano RA, Frantz GD, Tessier-Lavigne M, Bolon B, French DM, Ashkenazi A.

PLoS One. 2007 Jun 27;2(6):e575.


Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus.

Merchant M, Evangelista M, Luoh SM, Frantz GD, Chalasani S, Carano RA, van Hoy M, Ramirez J, Ogasawara AK, McFarland LM, Filvaroff EH, French DM, de Sauvage FJ.

Mol Cell Biol. 2005 Aug;25(16):7054-68.


COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas.

Dornan D, Bheddah S, Newton K, Ince W, Frantz GD, Dowd P, Koeppen H, Dixit VM, French DM.

Cancer Res. 2004 Oct 15;64(20):7226-30.


WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair.

French DM, Kaul RJ, D'Souza AL, Crowley CW, Bao M, Frantz GD, Filvaroff EH, Desnoyers L.

Am J Pathol. 2004 Sep;165(3):855-67.


Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.

Mariathasan S, Newton K, Monack DM, Vucic D, French DM, Lee WP, Roose-Girma M, Erickson S, Dixit VM.

Nature. 2004 Jul 8;430(6996):213-8. Epub 2004 Jun 9.


Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency.

Newton K, French DM, Yan M, Frantz GD, Dixit VM.

Mol Cell Biol. 2004 Feb;24(4):1608-13.


Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase.

Ruefli-Brasse AA, French DM, Dixit VM.

Science. 2003 Nov 28;302(5650):1581-4. Epub 2003 Oct 23.


BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.

Kayagaki N, Yan M, Seshasayee D, Wang H, Lee W, French DM, Grewal IS, Cochran AG, Gordon NC, Yin J, Starovasnik MA, Dixit VM.

Immunity. 2002 Oct;17(4):515-24.


Alpha(1)-adrenoceptor stimulation directly induces growth of vascular wall in vivo.

Erami C, Zhang H, Ho JG, French DM, Faber JE.

Am J Physiol Heart Circ Physiol. 2002 Oct;283(4):H1577-87. Epub 2002 Jul 8.


Stanniocalcin 1 alters muscle and bone structure and function in transgenic mice.

Filvaroff EH, Guillet S, Zlot C, Bao M, Ingle G, Steinmetz H, Hoeffel J, Bunting S, Ross J, Carano RA, Powell-Braxton L, Wagner GF, Eckert R, Gerritsen ME, French DM.

Endocrinology. 2002 Sep;143(9):3681-90.


A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice.

Nicholes K, Guillet S, Tomlinson E, Hillan K, Wright B, Frantz GD, Pham TA, Dillard-Telm L, Tsai SP, Stephan JP, Stinson J, Stewart T, French DM.

Am J Pathol. 2002 Jun;160(6):2295-307.


Streptococcus didelphis sp. nov., a streptococcus with marked catalase activity isolated from opossums (Didelphis virginiana) with suppurative dermatitis and liver fibrosis.

Rurangirwa FR, Teitzel CA, Cui J, French DM, McDonough PL, Besser T.

Int J Syst Evol Microbiol. 2000 Mar;50 Pt 2:759-65.


Emergence of Anaplasma marginale antigenic variants during persistent rickettsemia.

French DM, Brown WC, Palmer GH.

Infect Immun. 1999 Nov;67(11):5834-40.


Restriction of major surface protein 2 (MSP2) variants during tick transmission of the ehrlichia Anaplasma marginale.

Rurangirwa FR, Stiller D, French DM, Palmer GH.

Proc Natl Acad Sci U S A. 1999 Mar 16;96(6):3171-6.


Expression of Anaplasma marginale major surface protein 2 variants during persistent cyclic rickettsemia.

French DM, McElwain TF, McGuire TC, Palmer GH.

Infect Immun. 1998 Mar;66(3):1200-7. Erratum in: Infect Immun 1998 May;66(5):2400.


Expression of major surface protein 2 antigenic variants during acute Anaplasma marginale rickettsemia.

Eid G, French DM, Lundgren AM, Barbet AF, McElwain TF, Palmer GH.

Infect Immun. 1996 Mar;64(3):836-41.


DC General Hospital doctors' day address.

French DM.

J Natl Med Assoc. 1992 Mar;84(3):283-8. No abstract available.


AIDS and the acute abdomen.

Katz MH, French DM.

Emerg Med Clin North Am. 1989 Aug;7(3):575-89. Review.


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