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Items: 31


Plasmodium vivax Malaria viewed through the lens of an eradicated European strain.

van Dorp L, Gelabert P, Rieux A, de Manuel M, de-Dios T, Gopalakrishnan S, Carøe C, Sandoval-Velasco M, Fregel R, Olalde I, Escosa R, Aranda C, Huijben S, Mueller I, Marquès-Bonet T, Balloux F, Gilbert MTP, Lalueza-Fox C.

Mol Biol Evol. 2019 Nov 7. pii: msz264. doi: 10.1093/molbev/msz264. [Epub ahead of print]


Genetic affinities of an eradicated European Plasmodium falciparum strain.

de-Dios T, van Dorp L, Gelabert P, Carøe C, Sandoval-Velasco M, Fregel R, Escosa R, Aranda C, Huijben S, Balloux F, Gilbert MTP, Lalueza-Fox C.

Microb Genom. 2019 Sep;5(9). doi: 10.1099/mgen.0.000289. Epub 2019 Aug 20.


Mitogenomes illuminate the origin and migration patterns of the indigenous people of the Canary Islands.

Fregel R, Ordóñez AC, Santana-Cabrera J, Cabrera VM, Velasco-Vázquez J, Alberto V, Moreno-Benítez MA, Delgado-Darias T, Rodríguez-Rodríguez A, Hernández JC, Pais J, González-Montelongo R, Lorenzo-Salazar JM, Flores C, Cruz-de-Mercadal MC, Álvarez-Rodríguez N, Shapiro B, Arnay M, Bustamante CD.

PLoS One. 2019 Mar 20;14(3):e0209125. doi: 10.1371/journal.pone.0209125. eCollection 2019.


Aggressive or funerary cannibalism? Skull-cup and human bone manipulation in Cueva de El Toro (Early Neolithic, southern Iberia).

Santana J, Rodríguez-Santos FJ, Camalich-Massieu MD, Martín-Socas D, Fregel R.

Am J Phys Anthropol. 2019 May;169(1):31-54. doi: 10.1002/ajpa.23805. Epub 2019 Feb 25.


Ancient genomes from North Africa evidence prehistoric migrations to the Maghreb from both the Levant and Europe.

Fregel R, Méndez FL, Bokbot Y, Martín-Socas D, Camalich-Massieu MD, Santana J, Morales J, Ávila-Arcos MC, Underhill PA, Shapiro B, Wojcik G, Rasmussen M, Soares AER, Kapp J, Sockell A, Rodríguez-Santos FJ, Mikdad A, Trujillo-Mederos A, Bustamante CD.

Proc Natl Acad Sci U S A. 2018 Jun 26;115(26):6774-6779. doi: 10.1073/pnas.1800851115. Epub 2018 Jun 12. Erratum in: Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7231.


Mitochondrial DNA from the eradicated European Plasmodium vivax and P. falciparum from 70-year-old slides from the Ebro Delta in Spain.

Gelabert P, Sandoval-Velasco M, Olalde I, Fregel R, Rieux A, Escosa R, Aranda C, Paaijmans K, Mueller I, Gilbert MT, Lalueza-Fox C.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11495-11500. Epub 2016 Sep 26.


The early colonial atlantic world: New insights on the African Diaspora from isotopic and ancient DNA analyses of a multiethnic 15th-17th century burial population from the Canary Islands, Spain.

Santana J, Fregel R, Lightfoot E, Morales J, Alamón M, Guillén J, Moreno M, Rodríguez A.

Am J Phys Anthropol. 2016 Feb;159(2):300-12. doi: 10.1002/ajpa.22879. Epub 2015 Oct 12.


Carriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian Route.

Fregel R, Cabrera V, Larruga JM, Abu-Amero KK, González AM.

PLoS One. 2015 Jun 8;10(6):e0129839. doi: 10.1371/journal.pone.0129839. eCollection 2015.


Mitochondrial DNA haplogroup phylogeny of the dog: Proposal for a cladistic nomenclature.

Fregel R, Suárez NM, Betancor E, González AM, Cabrera VM, Pestano J.

Mitochondrion. 2015 May;22:75-84. doi: 10.1016/j.mito.2015.04.001. Epub 2015 Apr 11.


Isolation and prominent aboriginal maternal legacy in the present-day population of La Gomera (Canary Islands).

Fregel R, Cabrera VM, Larruga JM, Hernández JC, Gámez A, Pestano JJ, Arnay M, González AM.

Eur J Hum Genet. 2015 Sep;23(9):1236-43. doi: 10.1038/ejhg.2014.251. Epub 2014 Nov 19.


The history of the North African mitochondrial DNA haplogroup U6 gene flow into the African, Eurasian and American continents.

Secher B, Fregel R, Larruga JM, Cabrera VM, Endicott P, Pestano JJ, González AM.

BMC Evol Biol. 2014 May 19;14:109. doi: 10.1186/1471-2148-14-109.


Multiple ethnic origins of mitochondrial DNA lineages for the population of Mauritius.

Fregel R, Seetah K, Betancor E, Suárez NM, Čaval D, Caval S, Janoo A, Pestano J.

PLoS One. 2014 Mar 27;9(3):e93294. doi: 10.1371/journal.pone.0093294. eCollection 2014.


Mitochondrial DNA and Y-chromosome structure at the Mediterranean and Atlantic façades of the Iberian Peninsula.

Santos C, Fregel R, Cabrera VM, Alvarez L, Larruga JM, Ramos A, López MA, Pilar Aluja M, González AM.

Am J Hum Biol. 2014 Mar-Apr;26(2):130-41. doi: 10.1002/ajhb.22497. Epub 2013 Dec 26.


Introducing the Algerian mitochondrial DNA and Y-chromosome profiles into the North African landscape.

Bekada A, Fregel R, Cabrera VM, Larruga JM, Pestano J, Benhamamouch S, González AM.

PLoS One. 2013;8(2):e56775. doi: 10.1371/journal.pone.0056775. Epub 2013 Feb 19.


Genetic characterization, at the mitochondrial and nuclear DNA levels, of five Canary Island dog breeds.

Suárez NM, Betancor E, Fregel R, Pestano J.

Anim Genet. 2013 Aug;44(4):432-41. doi: 10.1111/age.12024. Epub 2013 Feb 6.


The loss of functional caspase-12 in Europe is a pre-neolithic event.

Hervella M, Plantinga TS, Alonso S, Ferwerda B, Izagirre N, Fontecha L, Fregel R, van der Meer JW, de-la-Rúa C, Netea MG.

PLoS One. 2012;7(5):e37022. doi: 10.1371/journal.pone.0037022. Epub 2012 May 16.


Ancient DNA from hunter-gatherer and farmer groups from Northern Spain supports a random dispersion model for the Neolithic expansion into Europe.

Hervella M, Izagirre N, Alonso S, Fregel R, Alonso A, Cabrera VM, de la Rúa C.

PLoS One. 2012;7(4):e34417. doi: 10.1371/journal.pone.0034417. Epub 2012 Apr 25. Erratum in: PLoS One. 2012;7(7). doi:10.1371/annotation/3dac0b4f-f76e-4bc1-8559-acb41b87b02c.


Low prevalence of lactase persistence in Neolithic South-West Europe.

Plantinga TS, Alonso S, Izagirre N, Hervella M, Fregel R, van der Meer JW, Netea MG, de la Rúa C.

Eur J Hum Genet. 2012 Jul;20(7):778-82. doi: 10.1038/ejhg.2011.254. Epub 2012 Jan 11. Erratum in: Eur J Hum Genet. 2012 Jul;20(7):810.


Mitochondrial DNA and Y-chromosome microstructure in Tunisia.

Ennafaa H, Fregel R, Khodjet-El-Khil H, González AM, Mahmoudi HA, Cabrera VM, Larruga JM, Benammar-Elgaaïed A.

J Hum Genet. 2011 Oct;56(10):734-41. doi: 10.1038/jhg.2011.92. Epub 2011 Aug 11.


HaploSearch: a tool for haplotype-sequence two-way transformation.

Fregel R, Delgado S.

Mitochondrion. 2011 Mar;11(2):366-7. doi: 10.1016/j.mito.2010.11.001. Epub 2010 Nov 6.


Using mitochondrial DNA to test the hypothesis of a European post-glacial human recolonization from the Franco-Cantabrian refuge.

García O, Fregel R, Larruga JM, Álvarez V, Yurrebaso I, Cabrera VM, González AM.

Heredity (Edinb). 2011 Jan;106(1):37-45. doi: 10.1038/hdy.2010.47. Epub 2010 Apr 21.


Improved ethanol precipitation of DNA.

Fregel R, González A, Cabrera VM.

Electrophoresis. 2010 Apr;31(8):1350-2. doi: 10.1002/elps.200900721.


Mitochondrial DNA patterns in the Macaronesia islands: Variation within and among archipelagos.

Santos C, Fregel R, Cabrera VM, González AM, Larruga JM, Lima M.

Am J Phys Anthropol. 2010 Apr;141(4):610-9. doi: 10.1002/ajpa.21180.


Extraction of high-quality host DNA from feces and regurgitated seeds: a useful tool for vertebrate ecological studies.

Marrero P, Fregel R, Cabrera VM, Nogales M.

Biol Res. 2009;42(2):147-51. doi: /S0716-97602009000200002. Epub 2009 Aug 20.


Temporal evolution of the ABO allele frequencies in the Canary Islands: the impact of the European colonization.

Fregel R, Betancor E, Suárez NM, Cabrera VM, Pestano J, Larruga JM, González AM.

Immunogenetics. 2009 Sep;61(9):603-10. doi: 10.1007/s00251-009-0393-8. Epub 2009 Aug 20.


Demographic history of Canary Islands male gene-pool: replacement of native lineages by European.

Fregel R, Gomes V, Gusmão L, González AM, Cabrera VM, Amorim A, Larruga JM.

BMC Evol Biol. 2009 Aug 3;9:181. doi: 10.1186/1471-2148-9-181.


The maternal aborigine colonization of La Palma (Canary Islands).

Fregel R, Pestano J, Arnay M, Cabrera VM, Larruga JM, González AM.

Eur J Hum Genet. 2009 Oct;17(10):1314-24. doi: 10.1038/ejhg.2009.46. Epub 2009 Apr 1.


Microwave improved Escherichia coli transformation.

Fregel R, Rodríguez V, Cabrera VM.

Lett Appl Microbiol. 2008 Apr;46(4):498-9. doi: 10.1111/j.1472-765X.2008.02333.x. Epub 2008 Feb 13.


Human mitochondrial DNA diversity in an archaeological site in al-Andalus: genetic impact of migrations from North Africa in medieval Spain.

Casas MJ, Hagelberg E, Fregel R, Larruga JM, González AM.

Am J Phys Anthropol. 2006 Dec;131(4):539-51.


Description of a simple multiplex PCR-SSCP method for AB0 genotyping and its application to the peopling of the Canary Islands.

Fregel R, Maca-Meyer N, Cabrera VM, González AM, Larruga JM.

Immunogenetics. 2005 Sep;57(8):572-8. Epub 2005 Sep 29.


Mitochondrial DNA diversity in 17th-18th century remains from Tenerife (Canary Islands).

Maca-Meyer N, Cabrera VM, Arnay M, Flores C, Fregel R, González AM, Larruga JM.

Am J Phys Anthropol. 2005 Aug;127(4):418-26.


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