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Items: 1 to 50 of 361

1.

Low-Background Acyl-Biotinyl Exchange Largely Eliminates the Coisolation of Non-S-Acylated Proteins and Enables Deep S-Acylproteomic Analysis.

Zhou B, Wang Y, Yan Y, Mariscal J, Di Vizio D, Freeman MR, Yang W.

Anal Chem. 2019 Aug 6;91(15):9858-9866. doi: 10.1021/acs.analchem.9b01520. Epub 2019 Jul 11.

PMID:
31251020
2.

A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.

Jan YJ, Yoon J, Chen JF, Teng PC, Yao N, Cheng S, Lozano A, Chu GCY, Chung H, Lu YT, Chen PJ, Wang JJ, Lee YT, Kim M, Zhu Y, Knudsen BS, Feng FY, Garraway IP, Gao AC, Chung LWK, Freeman MR, You S, Tseng HR, Posadas EM.

Theranostics. 2019 Apr 13;9(10):2812-2826. doi: 10.7150/thno.34485. eCollection 2019.

3.

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation.

Smith GA, Lin TH, Sheehan AE, Van der Goes van Naters W, Neukomm LJ, Graves HK, Bis-Brewer DM, Züchner S, Freeman MR.

Neuron. 2019 Jul 3;103(1):52-65.e6. doi: 10.1016/j.neuron.2019.04.017. Epub 2019 May 14.

4.

Caveolin-1 scaffolding domain peptide prevents hyperoxia-induced airway remodeling in a neonatal mouse model.

Vogel ER, Manlove LJ, Kuipers I, Thompson MA, Fang YH, Freeman MR, Britt RD Jr, Faksh A, Yang B, Prakash YS, Pabelick CM.

Am J Physiol Lung Cell Mol Physiol. 2019 Jul 1;317(1):L99-L108. doi: 10.1152/ajplung.00111.2018. Epub 2019 May 1.

PMID:
31042080
5.

Optimization of DNA extraction from human urinary samples for mycobiome community profiling.

Ackerman AL, Anger JT, Khalique MU, Ackerman JE, Tang J, Kim J, Underhill DM, Freeman MR; NIH Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP).

PLoS One. 2019 Apr 25;14(4):e0210306. doi: 10.1371/journal.pone.0210306. eCollection 2019.

6.

Quantitative proteomic analysis of prostate tissue specimens identifies deregulated protein complexes in primary prostate cancer.

Zhou B, Yan Y, Wang Y, You S, Freeman MR, Yang W.

Clin Proteomics. 2019 Apr 13;16:15. doi: 10.1186/s12014-019-9236-2. eCollection 2019.

7.

Guidance for elective single-embryo transfer should be applied to frozen embryo transfer cycles.

Freeman MR, Hinds MS, Howard KG, Howard JM, Hill GA.

J Assist Reprod Genet. 2019 May;36(5):939-946. doi: 10.1007/s10815-019-01433-w. Epub 2019 Mar 11.

PMID:
30859416
8.

Keratin 8 is a potential self-antigen in the coronary artery disease immunopeptidome: A translational approach.

Mihailovic PM, Lio WM, Herscovici R, Chyu KY, Yano J, Zhao X, Zhou J, Zhou B, Freeman MR, Yang W, Shah PK, Cercek B, Dimayuga PC.

PLoS One. 2019 Feb 27;14(2):e0213025. doi: 10.1371/journal.pone.0213025. eCollection 2019.

9.

A scalable filtration method for high throughput screening based on cell deformability.

Gill NK, Ly C, Nyberg KD, Lee L, Qi D, Tofig B, Reis-Sobreiro M, Dorigo O, Rao J, Wiedemeyer R, Karlan B, Lawrenson K, Freeman MR, Damoiseaux R, Rowat AC.

Lab Chip. 2019 Jan 15;19(2):343-357. doi: 10.1039/c8lc00922h.

PMID:
30566156
10.

ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis.

Rotinen M, You S, Yang J, Coetzee SG, Reis-Sobreiro M, Huang WC, Huang F, Pan X, Yáñez A, Hazelett DJ, Chu CY, Steadman K, Morrissey CM, Nelson PS, Corey E, Chung LWK, Freedland SJ, Di Vizio D, Garraway IP, Murali R, Knudsen BS, Freeman MR.

Nat Med. 2018 Dec;24(12):1887-1898. doi: 10.1038/s41591-018-0241-1. Epub 2018 Nov 26.

11.

Focal adhesion molecules regulate astrocyte morphology and glutamate transporters to suppress seizure-like behavior.

Cho S, Muthukumar AK, Stork T, Coutinho-Budd JC, Freeman MR.

Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11316-11321. doi: 10.1073/pnas.1800830115. Epub 2018 Oct 16.

12.

Identification of the Transcription Factor Relationships Associated with Androgen Deprivation Therapy Response and Metastatic Progression in Prostate Cancer.

Sharma NV, Pellegrini KL, Ouellet V, Giuste FO, Ramalingam S, Watanabe K, Adam-Granger E, Fossouo L, You S, Freeman MR, Vertino P, Conneely K, Osunkoya AO, Trudel D, Mes-Masson AM, Petros JA, Saad F, Moreno CS.

Cancers (Basel). 2018 Oct 11;10(10). pii: E379. doi: 10.3390/cancers10100379.

13.

Statin Therapy to Improve Prostate Cancer Outcomes: Who, When, and for How Long?

Allott EH, Freeman MR, Freedland SJ.

Eur Urol. 2018 Dec;74(6):702-703. doi: 10.1016/j.eururo.2018.08.012. Epub 2018 Aug 31. No abstract available.

PMID:
30177293
14.

Emerin Deregulation Links Nuclear Shape Instability to Metastatic Potential.

Reis-Sobreiro M, Chen JF, Novitskaya T, You S, Morley S, Steadman K, Gill NK, Eskaros A, Rotinen M, Chu CY, Chung LWK, Tanaka H, Yang W, Knudsen BS, Tseng HR, Rowat AC, Posadas EM, Zijlstra A, Di Vizio D, Freeman MR.

Cancer Res. 2018 Nov 1;78(21):6086-6097. doi: 10.1158/0008-5472.CAN-18-0608. Epub 2018 Aug 28.

PMID:
30154147
15.

Large extracellular vesicles carry most of the tumour DNA circulating in prostate cancer patient plasma.

Vagner T, Spinelli C, Minciacchi VR, Balaj L, Zandian M, Conley A, Zijlstra A, Freeman MR, Demichelis F, De S, Posadas EM, Tanaka H, Di Vizio D.

J Extracell Vesicles. 2018 Aug 7;7(1):1505403. doi: 10.1080/20013078.2018.1505403. eCollection 2018.

16.

Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

Peters OM, Lewis EA, Osterloh JM, Weiss A, Salameh JS, Metterville J, Brown RH, Freeman MR.

Hum Mol Genet. 2018 Nov 1;27(21):3761-3771. doi: 10.1093/hmg/ddy260.

17.

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model.

Waldron RT, Su HY, Piplani H, Capri J, Cohn W, Whitelegge JP, Faull KF, Sakkiah S, Abrol R, Yang W, Zhou B, Freeman MR, Pandol SJ, Lugea A.

Cell Mol Gastroenterol Hepatol. 2018 Jan 6;5(4):479-497. doi: 10.1016/j.jcmgh.2018.01.001. eCollection 2018.

18.

Cardiac MRI and radionuclide ventriculography for measurement of left ventricular ejection fraction in ICD candidates.

Kotha VK, Deva DP, Connelly KA, Freeman MR, Yan RT, Mangat I, Kirpalani A, Barfett JJ, Sloninko J, Lin HM, Graham JJ, Crean AM, Jimenez-Juan L, Dorian P, Yan AT.

Magn Reson Imaging. 2018 Oct;52:69-74. doi: 10.1016/j.mri.2018.05.012. Epub 2018 May 31.

PMID:
29859946
19.

Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer.

Allott EH, Masko EM, Freedland AR, Macias E, Pelton K, Solomon KR, Mostaghel EA, Thomas GV, Pizzo SV, Freeman MR, Freedland SJ.

Prostate Cancer Prostatic Dis. 2018 Jun;21(2):196-203. doi: 10.1038/s41391-018-0045-x. Epub 2018 May 23.

20.

Personalization of prostate cancer therapy through phosphoproteomics.

Yang W, Freeman MR, Kyprianou N.

Nat Rev Urol. 2018 Aug;15(8):483-497. doi: 10.1038/s41585-018-0014-0. Review.

PMID:
29752463
21.

RNAi screening identifies a mechanosensitive ROCK-JAK2-STAT3 network central to myofibroblast activation.

Oh RS, Haak AJ, Smith KMJ, Ligresti G, Choi KM, Xie T, Wang S, Walters PR, Thompson MA, Freeman MR, Manlove LJ, Chu VM, Feghali-Bostwick C, Roden AC, Schymeinsky J, Pabelick CM, Prakash YS, Vassallo R, Tschumperlin DJ.

J Cell Sci. 2018 May 15;131(10). pii: jcs209932. doi: 10.1242/jcs.209932.

22.

Genes involved in prostate cancer progression determine MRI visibility.

Li P, You S, Nguyen C, Wang Y, Kim J, Sirohi D, Ziembiec A, Luthringer D, Lin SC, Daskivich T, Wu J, Freeman MR, Saouaf R, Li D, Kim HL.

Theranostics. 2018 Feb 12;8(7):1752-1765. doi: 10.7150/thno.23180. eCollection 2018.

23.

Regulation of inside-out β1-integrin activation by CDCP1.

Pollan SG, Huang F, Sperger JM, Lang JM, Morrissey C, Cress AE, Chu CY, Bhowmick NA, You S, Freeman MR, Spassov DS, Moasser MM, Carter WG, Satapathy SR, Shah K, Knudsen BS.

Oncogene. 2018 May;37(21):2817-2836. doi: 10.1038/s41388-018-0142-2. Epub 2018 Mar 7.

PMID:
29511352
24.

Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration.

Farley JE, Burdett TC, Barria R, Neukomm LJ, Kenna KP, Landers JE, Freeman MR.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1358-1363. doi: 10.1073/pnas.1715837115. Epub 2018 Jan 2.

25.

Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study.

Jamnagerwalla J, Howard LE, Allott EH, Vidal AC, Moreira DM, Castro-Santamaria R, Andriole GL, Freeman MR, Freedland SJ.

Prostate Cancer Prostatic Dis. 2018 Jun;21(2):252-259. doi: 10.1038/s41391-017-0030-9. Epub 2017 Dec 27.

26.

A Systems Approach to Prostate Cancer Classification-Response.

You S, Freeman MR.

Cancer Res. 2017 Dec 15;77(24):7133-7135. doi: 10.1158/0008-5472.CAN-17-0239. Epub 2017 Dec 6. No abstract available.

27.

The secreted neurotrophin Spätzle 3 promotes glial morphogenesis and supports neuronal survival and function.

Coutinho-Budd JC, Sheehan AE, Freeman MR.

Genes Dev. 2017 Oct 15;31(20):2023-2038. doi: 10.1101/gad.305888.117. Epub 2017 Nov 14.

28.

Magnetic actuation and feedback cooling of a cavity optomechanical torque sensor.

Kim PH, Hauer BD, Clark TJ, Fani Sani F, Freeman MR, Davis JP.

Nat Commun. 2017 Nov 7;8(1):1355. doi: 10.1038/s41467-017-01380-z.

29.

Cross-linguistic phonotactic competition and cognitive control in bilinguals.

Freeman MR, Blumenfeld HK, Marian V.

J Cogn Psychol (Hove). 2017;29(7):783-794. doi: 10.1080/20445911.2017.1321553. Epub 2017 May 4.

30.

Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly.

Neukomm LJ, Burdett TC, Seeds AM, Hampel S, Coutinho-Budd JC, Farley JE, Wong J, Karadeniz YB, Osterloh JM, Sheehan AE, Freeman MR.

Neuron. 2017 Jul 5;95(1):78-91.e5. doi: 10.1016/j.neuron.2017.06.031.

31.

Brain-derived neurotrophic factor and airway fibrosis in asthma.

Freeman MR, Sathish V, Manlove L, Wang S, Britt RD Jr, Thompson MA, Pabelick CM, Prakash YS.

Am J Physiol Lung Cell Mol Physiol. 2017 Aug 1;313(2):L360-L370. doi: 10.1152/ajplung.00580.2016. Epub 2017 May 18.

32.

MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer.

Minciacchi VR, Spinelli C, Reis-Sobreiro M, Cavallini L, You S, Zandian M, Li X, Mishra R, Chiarugi P, Adam RM, Posadas EM, Viglietto G, Freeman MR, Cocucci E, Bhowmick NA, Di Vizio D.

Cancer Res. 2017 May 1;77(9):2306-2317. doi: 10.1158/0008-5472.CAN-16-2942. Epub 2017 Feb 15. Erratum in: Cancer Res. 2017 Jul 15;77(14 ):3961.

33.

Axon degeneration induces glial responses through Draper-TRAF4-JNK signalling.

Lu TY, MacDonald JM, Neukomm LJ, Sheehan AE, Bradshaw R, Logan MA, Freeman MR.

Nat Commun. 2017 Feb 6;8:14355. doi: 10.1038/ncomms14355.

34.

CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.

Alfaqih MA, Nelson ER, Liu W, Safi R, Jasper JS, Macias E, Geradts J, Thompson JW, Dubois LG, Freeman MR, Chang CY, Chi JT, McDonnell DP, Freedland SJ.

Cancer Res. 2017 Apr 1;77(7):1662-1673. doi: 10.1158/0008-5472.CAN-16-2738. Epub 2017 Jan 27.

35.

Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.

Masko EM, Alfaqih MA, Solomon KR, Barry WT, Newgard CB, Muehlbauer MJ, Valilis NA, Phillips TE, Poulton SH, Freedland AR, Sun S, Dambal SK, Sanders SE, Macias E, Freeman MR, Dewhirst MW, Pizzo SV, Freedland SJ.

Prostate. 2017 Apr;77(5):446-457. doi: 10.1002/pros.23282. Epub 2016 Nov 30.

36.

High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature that can be detected in the circulation of breast cancer patients.

Conley A, Minciacchi VR, Lee DH, Knudsen BS, Karlan BY, Citrigno L, Viglietto G, Tewari M, Freeman MR, Demichelis F, Di Vizio D.

RNA Biol. 2017 Mar 4;14(3):305-316. doi: 10.1080/15476286.2016.1259061. Epub 2016 Nov 18.

37.

Keratin 13 expression reprograms bone and brain metastases of human prostate cancer cells.

Li Q, Yin L, Jones LW, Chu GC, Wu JB, Huang JM, Li Q, You S, Kim J, Lu YT, Mrdenovic S, Wang R, Freeman MR, Garraway I, Lewis MS, Chung LW, Zhau HE.

Oncotarget. 2016 Dec 20;7(51):84645-84657. doi: 10.18632/oncotarget.13175.

38.

Neuromodulators signal through astrocytes to alter neural circuit activity and behaviour.

Ma Z, Stork T, Bergles DE, Freeman MR.

Nature. 2016 Nov 17;539(7629):428-432. doi: 10.1038/nature20145. Epub 2016 Nov 9.

39.

The current evidence on statin use and prostate cancer prevention: are we there yet?

Alfaqih MA, Allott EH, Hamilton RJ, Freeman MR, Freedland SJ.

Nat Rev Urol. 2017 Feb;14(2):107-119. doi: 10.1038/nrurol.2016.199. Epub 2016 Oct 25. Review.

40.

Nanocavity optomechanical torque magnetometry and radiofrequency susceptometry.

Wu M, Wu NL, Firdous T, Fani Sani F, Losby JE, Freeman MR, Barclay PE.

Nat Nanotechnol. 2017 Feb;12(2):127-131. doi: 10.1038/nnano.2016.226. Epub 2016 Oct 31.

PMID:
27798605
41.

Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET.

Huang F, Ma Z, Pollan S, Yuan X, Swartwood S, Gertych A, Rodriguez M, Mallick J, Bhele S, Guindi M, Dhall D, Walts AE, Bose S, de Peralta Venturina M, Marchevsky AM, Luthringer DJ, Feller SM, Berman B, Freeman MR, Alvord WG, Vande Woude G, Amin MB, Knudsen BS.

J Pathol Clin Res. 2016 Jul 1;2(4):210-222. eCollection 2016 Oct.

42.

Cultured circulating tumor cells and their derived xenografts for personalized oncology.

Wang R, Chu GCY, Mrdenovic S, Annamalai AA, Hendifar AE, Nissen NN, Tomlinson JS, Lewis M, Palanisamy N, Tseng HR, Posadas EM, Freeman MR, Pandol SJ, Zhau HE, Chung LWK.

Asian J Urol. 2016 Oct;3(4):240-253. doi: 10.1016/j.ajur.2016.08.005. Epub 2016 Aug 25. Review.

43.

Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs.

Qu Y, Zhou B, Yang W, Han B, Yu-Rice Y, Gao B, Johnson J, Svendsen CN, Freeman MR, Giuliano AE, Sareen D, Cui X.

Sci Rep. 2016 Aug 23;6:32007. doi: 10.1038/srep32007.

44.

Nanoscale Structure, Dynamics, and Aging Behavior of Metallic Glass Thin Films.

Burgess JA, Holt CM, Luber EJ, Fortin DC, Popowich G, Zahiri B, Concepcion P, Mitlin D, Freeman MR.

Sci Rep. 2016 Aug 8;6:30973. doi: 10.1038/srep30973.

45.

Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome.

You S, Knudsen BS, Erho N, Alshalalfa M, Takhar M, Al-Deen Ashab H, Davicioni E, Karnes RJ, Klein EA, Den RB, Ross AE, Schaeffer EM, Garraway IP, Kim J, Freeman MR.

Cancer Res. 2016 Sep 1;76(17):4948-58. doi: 10.1158/0008-5472.CAN-16-0902. Epub 2016 Jun 14.

46.

Phonotactic Constraints Are Activated across Languages in Bilinguals.

Freeman MR, Blumenfeld HK, Marian V.

Front Psychol. 2016 May 18;7:702. doi: 10.3389/fpsyg.2016.00702. eCollection 2016.

47.

Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species.

He J, Zhou R, Wu Z, Carrasco MA, Kurshan PT, Farley JE, Simon DJ, Wang G, Han B, Hao J, Heller E, Freeman MR, Shen K, Maniatis T, Tessier-Lavigne M, Zhuang X.

Proc Natl Acad Sci U S A. 2016 May 24;113(21):6029-34. doi: 10.1073/pnas.1605707113. Epub 2016 May 9.

48.

Dendrites actively restrain axon outgrowth and regeneration.

Francis MM, Freeman MR.

Proc Natl Acad Sci U S A. 2016 May 17;113(20):5465-6. doi: 10.1073/pnas.1605215113. Epub 2016 May 4. No abstract available.

49.

Vitamin D Reduces Inflammation-induced Contractility and Remodeling of Asthmatic Human Airway Smooth Muscle.

Britt RD Jr, Thompson MA, Freeman MR, Stewart AL, Pabelick CM, Prakash YS.

Ann Am Thorac Soc. 2016 Mar;13 Suppl 1:S97-8. doi: 10.1513/AnnalsATS.201508-540MG.

50.

Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.

Henninger N, Bouley J, Sikoglu EM, An J, Moore CM, King JA, Bowser R, Freeman MR, Brown RH Jr.

Brain. 2016 Apr;139(Pt 4):1094-105. doi: 10.1093/brain/aww001. Epub 2016 Feb 11.

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