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MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2.

Martínez de Paz A, Khajavi L, Martin H, Claveria-Gimeno R, Tom Dieck S, Cheema MS, Sanchez-Mut JV, Moksa MM, Carles A, Brodie NI, Sheikh TI, Freeman ME, Petrotchenko EV, Borchers CH, Schuman EM, Zytnicki M, Velazquez-Campoy A, Abian O, Hirst M, Esteller M, Vincent JB, Malnou CE, Ausió J.

Epigenetics Chromatin. 2019 Oct 10;12(1):63. doi: 10.1186/s13072-019-0298-1.


Analysis of Neuroretinal Rim by Age, Race, and Gender Using High-Density Three-Dimensional Spectral Domain Optical Coherence Tomography.

Antar H, Tsikata E, Ratanawongphaibul K, Zhang J, Shieh E, Lee R, Freeman M, Papadogeorgou G, Simavli H, Que C, Verticchio Vercellin AC, Khoueir Z, de Boer JF, Chen TC.

J Glaucoma. 2019 Oct 9. doi: 10.1097/IJG.0000000000001381. [Epub ahead of print]


Topological kink plasmons on magnetic-domain boundaries.

Jin D, Xia Y, Christensen T, Freeman M, Wang S, Fong KY, Gardner GC, Fallahi S, Hu Q, Wang Y, Engel L, Xiao ZL, Manfra MJ, Fang NX, Zhang X.

Nat Commun. 2019 Oct 8;10(1):4565. doi: 10.1038/s41467-019-12092-x.


A Study on the Effect of Patient Characteristics, Geographical Utilization, and Patient Outcomes for Total Pancreatectomy Alone and Total Pancreatectomy With Islet Autotransplantation in Patients With Pancreatitis in the United States.

Lara LF, Bellin MD, Ugbarugba E, Nathan JD, Witkowski P, Wijkstrom M, Steel JL, Smith KD, Singh VK, Schwarzenberg SJ, Pruett TL, Naziruddin B, Long-Simpson L, Kirchner VA, Gardner TB, Freeman ML, Dunn TB, Chinnakotla S, Beilman GJ, Adams DB, Morgan KA, Abu-El-Haija MA, Ahmad S, Posselt AM, Hughes MG, Conwell DL.

Pancreas. 2019 Oct 8. doi: 10.1097/MPA.0000000000001405. [Epub ahead of print]


Risk Factors Associated With Progression Toward Endocrine Insufficiency in Chronic Pancreatitis.

Gutama BW, Yang Y, Beilman GJ, Freeman ML, Kirchner VA, Pruett TL, Chinnakotla S, Downs EM, Trikudanathan G, Schwarzenberg SJ, Hodges JS, Bellin MD.

Pancreas. 2019 Oct 8. doi: 10.1097/MPA.0000000000001394. [Epub ahead of print]


Modeling cellular response in large-scale radiogenomic databases to advance precision radiotherapy.

Manem VS, Lambie M, Smith I, Smirnov P, Kofia V, Freeman M, Koritzinsky M, Abazeed ME, Haibe-Kains B, Bratman SV.

Cancer Res. 2019 Sep 26. pii: canres.0179.2019. doi: 10.1158/0008-5472.CAN-19-0179. [Epub ahead of print]


A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study of Adjunctive Pimavanserin in Patients With Major Depressive Disorder and an Inadequate Response to Therapy (CLARITY).

Fava M, Dirks B, Freeman MP, Papakostas GI, Shelton RC, Thase ME, Trivedi MH, Liu K, Stankovic S.

J Clin Psychiatry. 2019 Sep 24;80(6). pii: 19m12928. doi: 10.4088/JCP.19m12928.


Neonatal Toxic Shock Syndrome-Like Exanthematous Disease in North America.

Freeman MC, Mitchell S, Ibrahim J, Williams JV.

J Pediatric Infect Dis Soc. 2019 Sep 24. pii: piz060. doi: 10.1093/jpids/piz060. [Epub ahead of print]


Distal malignant obstruction managed by EUS-guided choledochoduodenostomy by use of an uncovered self-expanding metal stent.

Haseeb A, Freeman ML, Amateau SK.

Gastrointest Endosc. 2019 Oct;90(4):696-697. doi: 10.1016/j.gie.2019.03.013. No abstract available.


Comorbid Dysphagia and Dyspnea in Muscle Tension Dysphonia: A Global Laryngeal Musculoskeletal Problem.

McGarey PO Jr, Barone NA, Freeman M, Daniero JJ.

OTO Open. 2018 Aug 24;2(3):2473974X18795671. doi: 10.1177/2473974X18795671. eCollection 2018 Jul-Sep.


Neural JNK3 regulates blood flow recovery after hindlimb ischemia in mice via an Egr1/Creb1 axis.

Kant S, Craige SM, Chen K, Reif MM, Learnard H, Kelly M, Caliz AD, Tran KV, Ramo K, Peters OM, Freeman M, Davis RJ, Keaney JF Jr.

Nat Commun. 2019 Sep 17;10(1):4223. doi: 10.1038/s41467-019-11982-4.


Genome mining- and synthetic biology-enabled production of hypermodified peptides.

Bhushan A, Egli PJ, Peters EE, Freeman MF, Piel J.

Nat Chem. 2019 Oct;11(10):931-939. doi: 10.1038/s41557-019-0323-9. Epub 2019 Sep 9.


Time to relapse after a single administration of intravenous ketamine augmentation in unipolar treatment-resistant depression.

Salloum NC, Fava M, Hock RS, Freeman MP, Flynn M, Hoeppner B, Cusin C, Iosifescu DV, Trivedi MH, Sanacora G, Mathew SJ, Debattista C, Ionescu DF, Papakostas GI.

J Affect Disord. 2019 Sep 3;260:131-139. doi: 10.1016/j.jad.2019.09.017. [Epub ahead of print]


Withdrawal: Activation of the AMP-activated protein kinase by the anti-diabetic drug metformin in vivo : Role of mitochondrial reactive nitrogen species.

Zou MH, Kirkpatrick SS, Davis BJ, Nelson JS, Wiles WG 4th, Schlattner U, Neumann D, Brownlee M, Freeman MB, Goldman MH.

J Biol Chem. 2019 Sep 6;294(36):13525. doi: 10.1074/jbc.W119.010595. No abstract available.


International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major Depressive Disorder.

Guu TW, Mischoulon D, Sarris J, Hibbeln J, McNamara RK, Hamazaki K, Freeman MP, Maes M, Matsuoka YJ, Belmaker RH, Jacka F, Pariante C, Berk M, Marx W, Su KP.

Psychother Psychosom. 2019;88(5):263-273. doi: 10.1159/000502652. Epub 2019 Sep 3. Review.


Treatment patterns of malignant melanoma in the United States from 2011 to 2016: a retrospective cohort study.

Shah S, Raskin L, Cohan D, Freeman M, Hamid O.

Curr Med Res Opin. 2019 Sep 16:1-10. doi: 10.1080/03007995.2019.1662688. [Epub ahead of print]


Guided Imagery, Biofeedback, and Hypnosis: A Map of the Evidence [Internet].

Freeman M, Ayers C, Kondo K, Noonan K, O’Neil M, Morasco B, Kansagara D.

Washington (DC): Department of Veterans Affairs (US); 2019 Feb.


The implications of three major new trials for the effect of water, sanitation and hygiene on childhood diarrhea and stunting: a consensus statement.

Cumming O, Arnold BF, Ban R, Clasen T, Esteves Mills J, Freeman MC, Gordon B, Guiteras R, Howard G, Hunter PR, Johnston RB, Pickering AJ, Prendergast AJ, Prüss-Ustün A, Rosenboom JW, Spears D, Sundberg S, Wolf J, Null C, Luby SP, Humphrey JH, Colford JM Jr.

BMC Med. 2019 Aug 28;17(1):173. doi: 10.1186/s12916-019-1410-x.


Indirect Treatment Comparison of Nivolumab Versus Observation or Ipilimumab as Adjuvant Therapy in Resected Melanoma Using Pooled Clinical Trial Data.

Freeman M, Betts KA, Jiang S, Du EX, Gupte-Singh K, Lu Y, Rao S, Shoushtari AN.

Adv Ther. 2019 Oct;36(10):2783-2796. doi: 10.1007/s12325-019-01060-y. Epub 2019 Aug 22.


Bcl2-expressing quiescent type B neural stem cells in the V-SVZ are resistant to concurrent temozolomide/X-irradiation.

Cameron BD, Traver G, Roland JT, Brockman AA, Dean D, Johnson L, Boyd K, Ihrie RA, Freeman ML.

Stem Cells. 2019 Aug 20. doi: 10.1002/stem.3081. [Epub ahead of print]


Multiple Independent Origins of Apicomplexan-Like Parasites.

Mathur V, Kolísko M, Hehenberger E, Irwin NAT, Leander BS, Kristmundsson Á, Freeman MA, Keeling PJ.

Curr Biol. 2019 Sep 9;29(17):2936-2941.e5. doi: 10.1016/j.cub.2019.07.019. Epub 2019 Aug 15.


Efficacy of Biofeedback for Medical Conditions: an Evidence Map.

Kondo K, Noonan KM, Freeman M, Ayers C, Morasco BJ, Kansagara D.

J Gen Intern Med. 2019 Aug 14. doi: 10.1007/s11606-019-05215-z. [Epub ahead of print] Review.


SpHincterotomy for Acute Recurrent Pancreatitis Randomized Trial: Rationale, Methodology, and Potential Implications.

Coté GA, Durkalski-Mauldin VL, Serrano J, Klintworth E, Williams AW, Cruz-Monserrate Z, Arain M, Buxbaum JL, Conwell DL, Fogel EL, Freeman ML, Gardner TB, van Geenen E, Groce JR, Jonnalagadda SS, Keswani RN, Menon S, Moffatt DC, Papachristou GI, Ross A, Tarnasky PR, Wang AY, Wilcox CM, Hamilton F, Yadav D; SHARP Consortium.

Pancreas. 2019 Sep;48(8):1061-1067. doi: 10.1097/MPA.0000000000001370.


A systems approach to assessing environmental and economic effects of food loss and waste interventions in the United States.

Muth MK, Birney C, Cuéllar A, Finn SM, Freeman M, Galloway JN, Gee I, Gephart J, Jones K, Low L, Meyer E, Read Q, Smith T, Weitz K, Zoubek S.

Sci Total Environ. 2019 Oct 1;685:1240-1254. doi: 10.1016/j.scitotenv.2019.06.230. Epub 2019 Jun 17. Review.


Alternative approach to hemostatic particle spraying for treatment of GI bleeding by the use of cross-platform devices.

Haseeb A, Freeman ML, Amateau SK.

VideoGIE. 2019 Jun 10;4(8):386-388. doi: 10.1016/j.vgie.2019.04.010. eCollection 2019 Aug.


The impact of obesity on pregnancy outcomes among women with psychiatric disorders: Results from a prospective pregnancy registry.

Freeman MP, Goez-Mogollon L, Sosinsky AZ, Church TR, McElheny SA, Viguera AC, Cohen LS.

J Psychosom Res. 2019 Aug;123:109735. doi: 10.1016/j.jpsychores.2019.109735. Epub 2019 Jun 4.


Reducing chest radiography utilization in the medical intensive care unit.

Wu Y, Rose MQ, Freeman ML, Richard-Lany NP, Spaulding AC, Booth SC, Kelly DL, Franco PM.

J Am Assoc Nurse Pract. 2019 Jul 31. doi: 10.1097/JXX.0000000000000256. [Epub ahead of print]


Assessing longer-term effectiveness of a combined household-level piped water and sanitation intervention on child diarrhoea, acute respiratory infection, soil-transmitted helminth infection and nutritional status: a matched cohort study in rural Odisha, India.

Reese H, Routray P, Torondel B, Sinharoy SS, Mishra S, Freeman MC, Chang HH, Clasen T.

Int J Epidemiol. 2019 Jul 30. pii: dyz157. doi: 10.1093/ije/dyz157. [Epub ahead of print]


Implementation of an Opioid Guideline Impacts on Opioid Prescriptions, Adverse Outcomes, and an Association with a State Opioid-Related Fatalities.

Phillips AL, Thiese MS, Freeman M, Kartchner R, Hegmann KT.

J Occup Environ Med. 2019 Aug;61(8):653-658. doi: 10.1097/JOM.0000000000001640.


Pharmacotherapy for methamphetamine/amphetamine use disorder-a systematic review and meta-analysis.

Chan B, Freeman M, Kondo K, Ayers C, Montgomery J, Paynter R, Kansagara D.

Addiction. 2019 Jul 22. doi: 10.1111/add.14755. [Epub ahead of print] Review.


Impact of Gender and Door-to-Balloon Times on Long-Term Mortality in Patients Presenting With ST-Elevation Myocardial Infarction.

Murphy AC, Yudi MB, Farouque O, Dinh D, Duffy SJ, Brennan A, Reid CM, Andrianopoulos N, Koshy AN, Martin L, Dagan M, Freeman M, Blusztein D, Ajani AE, Clark DJ; Melbourne Interventional Group.

Am J Cardiol. 2019 Sep 15;124(6):833-841. doi: 10.1016/j.amjcard.2019.06.008. Epub 2019 Jun 24.


Case 22-2019: A 65-Year-Old Woman with Weakness, Dark Urine, and Dysphagia.

Freeman MW, Singh AK, Guidon AC, Arvikar SL, Goldstein RH, Clement NF.

N Engl J Med. 2019 Jul 18;381(3):275-283. doi: 10.1056/NEJMcpc1900589. No abstract available.


Dietary supplementation with Zyflamend poly-herbal extracts and fish oil inhibits intimal hyperplasia development following vascular intervention.

Buckley MR, Terry PD, Kirkpatrick SS, Arnold JD, McNally MM, Grandas OH, Freeman MB, Goldman MH, Whelan J, Mountain DJ.

Nutr Res. 2019 Jun 8;68:34-44. doi: 10.1016/j.nutres.2019.06.001. [Epub ahead of print]


Kinematic Evaluation of the GMK Sphere Implant During Gait Activities: A Dynamic Videofluoroscopy Study.

Schütz P, Taylor WR, Postolka B, Fucentese SF, Koch PP, Freeman MAR, Pinskerova V, List R.

J Orthop Res. 2019 Nov;37(11):2337-2347. doi: 10.1002/jor.24416. Epub 2019 Aug 7.


A 96-week, multinational, randomized, double-blind, parallel-group, clinical trial evaluating the safety and effectiveness of bexagliflozin as a monotherapy for adults with type 2 diabetes.

Halvorsen YC, Walford GA, Massaro J, Aftring RP, Freeman MW.

Diabetes Obes Metab. 2019 Jul 12. doi: 10.1111/dom.13833. [Epub ahead of print]


Beyond stereotypes of cerebral palsy: Exploring the lived experiences of young Canadians.

Hanes JE, Hlyva O, Rosenbaum P, Freeman M, Nguyen T, Palisano RJ, Gorter JW.

Child Care Health Dev. 2019 Sep;45(5):613-622. doi: 10.1111/cch.12705. Epub 2019 Jul 24.


The direct medical cost of type 2 diabetes mellitus in South Africa: a cost of illness study.

Erzse A, Stacey N, Chola L, Tugendhaft A, Freeman M, Hofman K.

Glob Health Action. 2019;12(1):1636611. doi: 10.1080/16549716.2019.1636611.


The Impact of Out-of-Hours Presentation on Clinical Outcomes in ST-Elevation Myocardial Infarction.

Biswas S, Brennan A, Duffy SJ, Andrianopoulos N, Chan W, Walton A, Noaman S, Shaw JA, Ajani A, Clark DJ, Freeman M, Hiew C, Oqueli E, Lefkovits J, Reid CM, Stub D.

Heart Lung Circ. 2019 Jun 22. pii: S1443-9506(19)31320-4. doi: 10.1016/j.hlc.2019.05.184. [Epub ahead of print]


Low-Background Acyl-Biotinyl Exchange Largely Eliminates the Coisolation of Non-S-Acylated Proteins and Enables Deep S-Acylproteomic Analysis.

Zhou B, Wang Y, Yan Y, Mariscal J, Di Vizio D, Freeman MR, Yang W.

Anal Chem. 2019 Aug 6;91(15):9858-9866. doi: 10.1021/acs.analchem.9b01520. Epub 2019 Jul 11.


Complete Genome Sequences of Staphylococcus epidermidis Myophages Quidividi, Terranova, and Twillingate.

Freeman ME, Kenny SE, Lanier A, Cater K, Wilhite MC, Gamble P, O'Leary CJ, Hatoum-Aslan A, Young RF 3rd, Liu M.

Microbiol Resour Announc. 2019 Jun 27;8(26). pii: e00598-19. doi: 10.1128/MRA.00598-19.


The Effect of Time to Postoperative Radiation Therapy on Survival in Resected Merkel Cell Carcinoma.

Shinde A, Verma V, Jones BL, Li R, Glaser S, Freeman M, Melstrom L, Kang R, Parvathaneni U, Modi B, Amini A.

Am J Clin Oncol. 2019 Aug;42(8):636-642. doi: 10.1097/COC.0000000000000565.


A Circulating Tumor Cell-RNA Assay for Assessment of Androgen Receptor Signaling Inhibitor Sensitivity in Metastatic Castration-Resistant Prostate Cancer.

Jan YJ, Yoon J, Chen JF, Teng PC, Yao N, Cheng S, Lozano A, Chu GCY, Chung H, Lu YT, Chen PJ, Wang JJ, Lee YT, Kim M, Zhu Y, Knudsen BS, Feng FY, Garraway IP, Gao AC, Chung LWK, Freeman MR, You S, Tseng HR, Posadas EM.

Theranostics. 2019 Apr 13;9(10):2812-2826. doi: 10.7150/thno.34485. eCollection 2019.


ECMO as a rescue therapy for cardiogenic shock and a bridge to LVAD.

Freeman M, Lee M.

JAAPA. 2019 Jul;32(7):34-37. doi: 10.1097/01.JAA.0000558388.24105.e6.


PulseNet: Entering the Age of Next-Generation Sequencing.

Ribot EM, Freeman M, Hise KB, Gerner-Smidt P.

Foodborne Pathog Dis. 2019 Jul;16(7):451-456. doi: 10.1089/fpd.2019.2634. Epub 2019 Jun 26.


Surveillance imaging for metastasis in high-risk melanoma: importance in individualized patient care and survivorship.

Freeman M, Laks S.

Melanoma Manag. 2019 Apr 18;6(1):MMT12. doi: 10.2217/mmt-2019-0003. eCollection 2019 Mar. Review.


Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III.

Chang CL, Weigel AV, Ioannou MS, Pasolli HA, Xu CS, Peale DR, Shtengel G, Freeman M, Hess HF, Blackstone C, Lippincott-Schwartz J.

J Cell Biol. 2019 Aug 5;218(8):2583-2599. doi: 10.1083/jcb.201902061. Epub 2019 Jun 21.


Design of a parallel cluster-randomized trial assessing the impact of a demand-side sanitation and hygiene intervention on sustained behavior change and mental well-being in rural and peri-urban Amhara, Ethiopia: Andilaye study protocol.

Delea MG, Snyder JS, Belew M, Caruso BA, Garn JV, Sclar GD, Woreta M, Zewudie K, Gebremariam A, Freeman MC.

BMC Public Health. 2019 Jun 21;19(1):801. doi: 10.1186/s12889-019-7040-6.


Complete Genome Sequence of Serratia marcescens Phage MTx.

Graham K, Freeman M, Newkirk H, Liu M, Cahill J, Ramsey J.

Microbiol Resour Announc. 2019 Jun 20;8(25). pii: e00573-19. doi: 10.1128/MRA.00573-19.


The effect of temporal variation in feed quality and quantity on the diurnal feeding behaviour of dairy cows.

John AJ, Garcia SC, Kerrisk KL, Freeman MJ, Islam MR, Clark CEF.

Animal. 2019 Jun 20:1-8. doi: 10.1017/S1751731119001198. [Epub ahead of print]


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