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The paranoia as defence model of persecutory delusions: a systematic review and meta-analysis.

Murphy P, Bentall RP, Freeman D, O'Rourke S, Hutton P.

Lancet Psychiatry. 2018 Oct 9. pii: S2215-0366(18)30339-0. doi: 10.1016/S2215-0366(18)30339-0. [Epub ahead of print]


Intelligent Perioperative System: Towards Real-time Big Data Analytics in Surgery Risk Assessment.

Feng Z, Bhat RR, Yuan X, Freeman D, Baslanti T, Bihorac A, Li X.

DASC PICom DataCom CyberSciTech 2017 (2017). 2017 Nov;2017:1254-1259. doi: 10.1109/DASC-PICom-DataCom-CyberSciTec.2017.201.


Effect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial.

Espie CA, Emsley R, Kyle SD, Gordon C, Drake CL, Siriwardena AN, Cape J, Ong JC, Sheaves B, Foster R, Freeman D, Costa-Font J, Marsden A, Luik AI.

JAMA Psychiatry. 2018 Sep 25. doi: 10.1001/jamapsychiatry.2018.2745. [Epub ahead of print]


Insomnia, negative affect, and psychotic experiences: Modelling pathways over time in a clinical observational study.

Reeve S, Nickless A, Sheaves B, Freeman D.

Psychiatry Res. 2018 Aug 25;269:673-680. doi: 10.1016/j.psychres.2018.08.090. [Epub ahead of print]


Sleep Disorders in Early Psychosis: Incidence, Severity, and Association With Clinical Symptoms.

Reeve S, Sheaves B, Freeman D.

Schizophr Bull. 2018 Sep 8. doi: 10.1093/schbul/sby129. [Epub ahead of print]


The Experience of Sleep Problems and Their Treatment in Young People at Ultra-High Risk of Psychosis: A Thematic Analysis.

Waite F, Bradley J, Chadwick E, Reeve S, Bird JC, Freeman D.

Front Psychiatry. 2018 Aug 24;9:375. doi: 10.3389/fpsyt.2018.00375. eCollection 2018.


Sleep duration and psychotic experiences in patients at risk of psychosis: A secondary analysis of the EDIE-2 trial.

Reeve S, Nickless A, Sheaves B, Hodgekins J, Stewart SLK, Gumley A, Fowler D, Morrison A, Freeman D.

Schizophr Res. 2018 Aug 16. pii: S0920-9964(18)30498-5. doi: 10.1016/j.schres.2018.08.006. [Epub ahead of print]


Public acceptability of computer-controlled antibiotic management: An exploration of automated dosing and opportunities for implementation.

Rawson TM, Ming D, Gowers SA, Freeman DM, Herrero P, Georgiou P, Cass AE, O'Hare D, Holmes AH.

J Infect. 2018 Aug 10. pii: S0163-4453(18)30250-0. doi: 10.1016/j.jinf.2018.08.005. [Epub ahead of print]


Automated psychological therapy using immersive virtual reality for treatment of fear of heights: a single-blind, parallel-group, randomised controlled trial.

Freeman D, Haselton P, Freeman J, Spanlang B, Kishore S, Albery E, Denne M, Brown P, Slater M, Nickless A.

Lancet Psychiatry. 2018 Aug;5(8):625-632. doi: 10.1016/S2215-0366(18)30226-8. Epub 2018 Jul 11.


Cost-effectiveness of cognitive-behavioural therapy for sleep disorder added to usual care in patients with schizophrenia: the BEST study.

Tsiachristas A, Waite F, Freeman D, Luengo-Fernandez R.

BJPsych Open. 2018 Apr 19;4(3):126-135. doi: 10.1192/bjo.2018.2. eCollection 2018 May.


Toxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenone.

Harris G, Eschment M, Orozco SP, McCaffery JM, Maclennan R, Severin D, Leist M, Kleensang A, Pamies D, Maertens A, Hogberg HT, Freeman D, Kirkwood A, Hartung T, Smirnova L.

Arch Toxicol. 2018 Aug;92(8):2587-2606. doi: 10.1007/s00204-018-2250-8. Epub 2018 Jun 28.


Evaluation of inhaler technique and achievement and maintenance of mastery of budesonide/formoterol Spiromax® compared with budesonide/formoterol Turbuhaler® in adult patients with asthma: the Easy Low Instruction Over Time (ELIOT) study.

Price DB, Thomas V, Richard Dekhuijzen PN, Bosnic-Anticevich S, Roche N, Lavorini F, Raju P, Freeman D, Nicholls C, Small IR, Sims E, Safioti G, Canvin J, Chrystyn H.

BMC Pulm Med. 2018 Jun 28;18(1):107. doi: 10.1186/s12890-018-0665-x.


Group-Based Worry Intervention for Persecutory Delusions: an Initial Feasibility Study.

Isham L, Grafahrend H, Nickless A, Pugh K, Pleasants S, Smedley N, Freeman D, Mulligan A.

Behav Cogn Psychother. 2018 Sep;46(5):619-625. doi: 10.1017/S1352465818000383. Epub 2018 Jun 20.


Links between psychotic and neurotic symptoms in the general population: an analysis of longitudinal British National Survey data using Directed Acyclic Graphs.

Kuipers J, Moffa G, Kuipers E, Freeman D, Bebbington P.

Psychol Med. 2018 May 29:1-8. doi: 10.1017/S0033291718000879. [Epub ahead of print]


mTOR signaling regulates central and peripheral circadian clock function.

Ramanathan C, Kathale ND, Liu D, Lee C, Freeman DA, Hogenesch JB, Cao R, Liu AC.

PLoS Genet. 2018 May 11;14(5):e1007369. doi: 10.1371/journal.pgen.1007369. eCollection 2018 May.


Altered Extracellular Vesicle Concentration, Cargo and Function in Diabetes Mellitus.

Freeman DW, Noren Hooten N, Eitan E, Green J, Mode NA, Bodogai M, Zhang Y, Lehrmann E, Zonderman AB, Biragyn A, Egan J, Becker KG, Mattson MP, Ejiogu N, Evans MK.

Diabetes. 2018 May 2. pii: db171308. doi: 10.2337/db17-1308. [Epub ahead of print]


Adapted CBT to Stabilize Sleep on Psychiatric Wards: a Transdiagnostic Treatment Approach.

Sheaves B, Isham L, Bradley J, Espie C, Barrera A, Waite F, Harvey AG, Attard C, Freeman D.

Behav Cogn Psychother. 2018 Nov;46(6):661-675. doi: 10.1017/S1352465817000789. Epub 2018 Apr 4.


Genome-wide analysis of adolescent psychotic-like experiences shows genetic overlap with psychiatric disorders.

Pain O, Dudbridge F, Cardno AG, Freeman D, Lu Y, Lundstrom S, Lichtenstein P, Ronald A.

Am J Med Genet B Neuropsychiatr Genet. 2018 Jun;177(4):416-425. doi: 10.1002/ajmg.b.32630. Epub 2018 Mar 31.


Practical strategies when using a stable isotope labeled microtracer for absolute bioavailability assessment: A case study of a high oral dose clinical candidate GDC-0810.

Chen B, Lu P, Freeman D, Gao Y, Choo E, DeMent K, Savage S, Zhang K, Milanwoski D, Liu L, Dean B, Deng Y.

J Pharm Biomed Anal. 2018 May 30;154:116-122. doi: 10.1016/j.jpba.2018.02.050. Epub 2018 Feb 23.


Legislative and Policy Developments and Imperatives for Advancing the Primary Care Behavioral Health (PCBH) Model.

Freeman DS, Hudgins C, Hornberger J.

J Clin Psychol Med Settings. 2018 Jun;25(2):210-223. doi: 10.1007/s10880-018-9557-8.


Distribution of Fatty Acids and Lipids During Pregnancy.

Chavan-Gautam P, Rani A, Freeman DJ.

Adv Clin Chem. 2018;84:209-239. doi: 10.1016/bs.acc.2017.12.006. Epub 2018 Feb 1.


Schematic beliefs and problem solving performance predict depression in people experiencing persecutory delusions.

Vorontsova N, Garety P, Freeman D.

J Psychiatr Res. 2018 May;100:5-7. doi: 10.1016/j.jpsychires.2018.02.010. Epub 2018 Feb 13.


Financing the Primary Care Behavioral Health Model.

Freeman DS, Manson L, Howard J, Hornberger J.

J Clin Psychol Med Settings. 2018 Jun;25(2):197-209. doi: 10.1007/s10880-017-9529-4.


Fifty years of colic surgery.

Freeman DE.

Equine Vet J. 2018 Jul;50(4):423-435. doi: 10.1111/evj.12817. Epub 2018 Mar 12. Review.


Epidemiological Review of Francisella Tularensis: A Case Study in the Complications of Dual Diagnoses.

Stidham RA, Freeman DB, von Tersch RL, Sullivan PJ, Tostenson SD.

PLoS Curr. 2018 Jan 18;10. pii: ecurrents.outbreaks.8eb0b55f377abc2d250314bbb8fc9d6d. doi: 10.1371/currents.outbreaks.8eb0b55f377abc2d250314bbb8fc9d6d.


Pre-conception maternal erythrocyte saturated to unsaturated fatty acid ratio predicts pregnancy after natural cycle frozen embryo transfer.

Onyiaodike CC, Murray HM, Zhang R, Meyer BJ, Jordan F, Brown EA, Nibbs RJB, Lyall H, Sattar N, Nelson SM, Freeman DJ.

Sci Rep. 2018 Jan 19;8(1):1216. doi: 10.1038/s41598-018-19500-0.


Authors' reply to a comment on "Body image and paranoia".

Waite F, Freeman D.

Psychiatry Res. 2018 May;263:281. doi: 10.1016/j.psychres.2017.12.059. Epub 2017 Dec 23. No abstract available.


A Sub-millimeter, Inductively Powered Neural Stimulator.

Freeman DK, O'Brien JM, Kumar P, Daniels B, Irion RA, Shraytah L, Ingersoll BK, Magyar AP, Czarnecki A, Wheeler J, Coppeta JR, Abban MP, Gatzke R, Fried SI, Lee SW, Duwel AE, Bernstein JJ, Widge AS, Hernandez-Reynoso A, Kanneganti A, Romero-Ortega MI, Cogan SF.

Front Neurosci. 2017 Nov 27;11:659. doi: 10.3389/fnins.2017.00659. eCollection 2017.


Fractional exhaled nitric oxide as a predictor of response to inhaled corticosteroids in patients with non-specific respiratory symptoms and insignificant bronchodilator reversibility: a randomised controlled trial.

Price DB, Buhl R, Chan A, Freeman D, Gardener E, Godley C, Gruffydd-Jones K, McGarvey L, Ohta K, Ryan D, Syk J, Tan NC, Tan T, Thomas M, Yang S, Konduru PR, Ngantcha M, d'Alcontres MS, Lapperre TS.

Lancet Respir Med. 2018 Jan;6(1):29-39. doi: 10.1016/S2213-2600(17)30424-1. Epub 2017 Nov 3.


Stabilising sleep for patients admitted at acute crisis to a psychiatric hospital (OWLS): an assessor-blind pilot randomised controlled trial.

Sheaves B, Freeman D, Isham L, McInerney J, Nickless A, Yu LM, Rek S, Bradley J, Reeve S, Attard C, Espie CA, Foster R, Wirz-Justice A, Chadwick E, Barrera A.

Psychol Med. 2018 Jul;48(10):1694-1704. doi: 10.1017/S0033291717003191. Epub 2017 Nov 7.


A twin study exploring the association between childhood emotional and behaviour problems and specific psychotic experiences in a community sample of adolescents.

Shakoor S, McGuire P, Cardno AG, Freeman D, Ronald A.

J Child Psychol Psychiatry. 2018 May;59(5):565-573. doi: 10.1111/jcpp.12839. Epub 2017 Nov 3.


SlowMo, a digital therapy targeting reasoning in paranoia, versus treatment as usual in the treatment of people who fear harm from others: study protocol for a randomised controlled trial.

Garety PA, Ward T, Freeman D, Fowler D, Emsley R, Dunn G, Kuipers E, Bebbington P, Waller H, Greenwood K, Rus-Calafell M, McGourty A, Hardy A.

Trials. 2017 Nov 2;18(1):510. doi: 10.1186/s13063-017-2242-7.


The effects of cannabidiol on persecutory ideation and anxiety in a high trait paranoid group.

Hundal H, Lister R, Evans N, Antley A, Englund A, Murray RM, Freeman D, Morrison PD.

J Psychopharmacol. 2018 Mar;32(3):276-282. doi: 10.1177/0269881117737400. Epub 2017 Oct 31.


Treating Sleep Problems in Young People at Ultra-High Risk of Psychosis: A Feasibility Case Series.

Bradley J, Freeman D, Chadwick E, Harvey AG, Mullins B, Johns L, Sheaves B, Lennox B, Broome M, Waite F.

Behav Cogn Psychother. 2018 May;46(3):276-291. doi: 10.1017/S1352465817000601. Epub 2017 Oct 30.


Motion microscopy for visualizing and quantifying small motions.

Wadhwa N, Chen JG, Sellon JB, Wei D, Rubinstein M, Ghaffari R, Freeman DM, Büyüköztürk O, Wang P, Sun S, Kang SH, Bertoldi K, Durand F, Freeman WT.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11639-11644. doi: 10.1073/pnas.1703715114. Epub 2017 Oct 16.


Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes.

Jayabalan N, Nair S, Nuzhat Z, Rice GE, Zuñiga FA, Sobrevia L, Leiva A, Sanhueza C, Gutiérrez JA, Lappas M, Freeman DJ, Salomon C.

Front Endocrinol (Lausanne). 2017 Sep 27;8:239. doi: 10.3389/fendo.2017.00239. eCollection 2017. Review.


Body image and paranoia.

Waite F, Freeman D.

Psychiatry Res. 2017 Dec;258:136-140. doi: 10.1016/j.psychres.2017.10.007. Epub 2017 Oct 3.


British Thoracic Society quality standards for home oxygen use in adults.

Suntharalingam J, Wilkinson T, Annandale J, Davey C, Fielding R, Freeman D, Gibbons M, Hardinge M, Hippolyte S, Knowles V, Lee C, MacNee W, Pollington J, Vora V, Watts T, Wijesinghe M.

BMJ Open Respir Res. 2017 Sep 18;4(1):e000223. doi: 10.1136/bmjresp-2017-000223. eCollection 2017.


Response to Letter to the Editor on "Effectiveness of Bupivacaine Liposome Injectable Suspension for Postoperative Pain Control in Total Knee Arthroplasty: A Prospective, Randomized, Double Blind, Controlled Study".

Aiello PM, Freeman DC, Warritay OK, DeClaire JH.

J Arthroplasty. 2018 Jan;33(1):302-303. doi: 10.1016/j.arth.2017.08.029. Epub 2017 Sep 21. No abstract available.


Asking About Pets Enhances Patient Communication and Care: A Pilot Study.

Hodgson K, Darling M, Freeman D, Monavvari A.

Inquiry. 2017 Jan 1;54:46958017734030. doi: 10.1177/0046958017734030.


Disrupting Sleep: The Effects of Sleep Loss on Psychotic Experiences Tested in an Experimental Study With Mediation Analysis.

Reeve S, Emsley R, Sheaves B, Freeman D.

Schizophr Bull. 2018 Apr 6;44(3):662-671. doi: 10.1093/schbul/sbx103.


Coffee inhibition of CYP3A4 in vitro was not translated to a grapefruit-like pharmacokinetic interaction clinically.

Dresser GK, Urquhart BL, Proniuk J, Tieu A, Freeman DJ, Arnold JM, Bailey DG.

Pharmacol Res Perspect. 2017 Oct;5(5). doi: 10.1002/prp2.346.


The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis.

Freeman D, Sheaves B, Goodwin GM, Yu LM, Nickless A, Harrison PJ, Emsley R, Luik AI, Foster RG, Wadekar V, Hinds C, Gumley A, Jones R, Lightman S, Jones S, Bentall R, Kinderman P, Rowse G, Brugha T, Blagrove M, Gregory AM, Fleming L, Walklet E, Glazebrook C, Davies EB, Hollis C, Haddock G, John B, Coulson M, Fowler D, Pugh K, Cape J, Moseley P, Brown G, Hughes C, Obonsawin M, Coker S, Watkins E, Schwannauer M, MacMahon K, Siriwardena AN, Espie CA.

Lancet Psychiatry. 2017 Oct;4(10):749-758. doi: 10.1016/S2215-0366(17)30328-0. Epub 2017 Sep 6.


Extracellular Vesicles from Adipose Tissue-A Potential Role in Obesity and Type 2 Diabetes?

Gao X, Salomon C, Freeman DJ.

Front Endocrinol (Lausanne). 2017 Aug 18;8:202. doi: 10.3389/fendo.2017.00202. eCollection 2017. Review.


Metal ion coordination in the E. coli Nudix hydrolase dihydroneopterin triphosphate pyrophosphatase: New clues into catalytic mechanism.

Hill SE, Nguyen E, Ukachukwu CU, Freeman DM, Quirk S, Lieberman RL.

PLoS One. 2017 Jul 25;12(7):e0180241. doi: 10.1371/journal.pone.0180241. eCollection 2017.


Effect of lidocaine on inflammation in equine jejunum subjected to manipulation only and remote to intestinal segments subjected to ischemia.

Bauck AG, Grosche A, Morton AJ, Graham AS, Vickroy TW, Freeman DE.

Am J Vet Res. 2017 Aug;78(8):977-989. doi: 10.2460/ajvr.78.8.977.


Blood eosinophil count and exacerbation risk in patients with COPD.

Kerkhof M, Sonnappa S, Postma DS, Brusselle G, Agustí A, Anzueto A, Jones R, Papi A, Pavord I, Pizzichini E, Popov T, Roche N, Ryan D, Thomas M, Vogelmeier C, Chisholm A, Freeman D, Bafadhel M, Hillyer EV, Price DB.

Eur Respir J. 2017 Jul 20;50(1). pii: 1700761. doi: 10.1183/13993003.00761-2017. Print 2017 Jul. No abstract available.


Cognitive, affective, and social factors maintaining paranoia in adolescents with mental health problems: A longitudinal study.

Bird JC, Waite F, Rowsell E, Fergusson EC, Freeman D.

Psychiatry Res. 2017 Nov;257:34-39. doi: 10.1016/j.psychres.2017.07.023. Epub 2017 Jul 13.


Nightmares in the general population: identifying potential causal factors.

Rek S, Sheaves B, Freeman D.

Soc Psychiatry Psychiatr Epidemiol. 2017 Sep;52(9):1123-1133. doi: 10.1007/s00127-017-1408-7. Epub 2017 Jul 15.


Normal pregnancy is associated with an increase in thrombin generation from the very early stages of the first trimester.

Bagot CN, Leishman E, Onyiaodike CC, Jordan F, Freeman DJ.

Thromb Res. 2017 Sep;157:49-54. doi: 10.1016/j.thromres.2017.06.027. Epub 2017 Jun 29.


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