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Items: 22

1.

HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers.

Nyanhete TE, Frisbee AL, Bradley T, Faison WJ, Robins E, Payne T, Freel SA, Sawant S, Weinhold KJ, Wiehe K, Haynes BF, Ferrari G, Li QJ, Moody MA, Tomaras GD.

Sci Rep. 2019 Jul 15;9(1):10165. doi: 10.1038/s41598-019-46462-8.

2.

Advancement of multidisciplinary education and research in translational sciences: MERITS program development at Duke University.

Freel SA, Fish LJ, Mirman B, Sudan R, Devi GR.

J Clin Transl Sci. 2018 Jul 6;2(1):57-62. doi: 10.1017/cts.2018.17. eCollection 2018 Feb.

3.

Multidisciplinary Mentoring Programs to Enhance Junior Faculty Research Grant Success.

Freel SA, Smith PC, Burns EN, Downer JB, Brown AJ, Dewhirst MW.

Acad Med. 2017 Oct;92(10):1410-1415. doi: 10.1097/ACM.0000000000001620.

4.

Developing a holistic policy and intervention framework for global mental health.

Khenti A, Fréel S, Trainor R, Mohamoud S, Diaz P, Suh E, Bobbili SJ, Sapag JC.

Health Policy Plan. 2016 Feb;31(1):37-45. doi: 10.1093/heapol/czv016. Epub 2015 Mar 31.

PMID:
25832419
5.

Young leaders in public health in Latin America and the Caribbean: insights from the eSAC project.

Cabieses B, Julian S, Mejia F, Farach N, Faba G, Cortinois A, Freel S.

Rev Panam Salud Publica. 2014 Oct;36(4):279-80. No abstract available.

PMID:
25563155
6.

Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition.

Payne TL, Blackinton J, Frisbee A, Pickeral J, Sawant S, Vandergrift NA, Freel SA, Ferrari G, Keene JD, Tomaras GD.

J Virol. 2014 Sep 1;88(17):9514-28. doi: 10.1128/JVI.00802-14. Epub 2014 Jun 4.

7.

Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.

Freel SA, Picking RA, Ferrari G, Ding H, Ochsenbauer C, Kappes JC, Kirchherr JL, Soderberg KA, Weinhold KJ, Cunningham CK, Denny TN, Crump JA, Cohen MS, McMichael AJ, Haynes BF, Tomaras GD.

J Virol. 2012 Jun;86(12):6835-46. doi: 10.1128/JVI.00437-12. Epub 2012 Apr 18.

8.

Dynamic antibody specificities and virion concentrations in circulating immune complexes in acute to chronic HIV-1 infection.

Liu P, Overman RG, Yates NL, Alam SM, Vandergrift N, Chen Y, Graw F, Freel SA, Kappes JC, Ochsenbauer C, Montefiori DC, Gao F, Perelson AS, Cohen MS, Haynes BF, Tomaras GD.

J Virol. 2011 Nov;85(21):11196-207. doi: 10.1128/JVI.05601-11. Epub 2011 Aug 24.

9.

Primary infection by a human immunodeficiency virus with atypical coreceptor tropism.

Jiang C, Parrish NF, Wilen CB, Li H, Chen Y, Pavlicek JW, Berg A, Lu X, Song H, Tilton JC, Pfaff JM, Henning EA, Decker JM, Moody MA, Drinker MS, Schutte R, Freel S, Tomaras GD, Nedellec R, Mosier DE, Haynes BF, Shaw GM, Hahn BH, Doms RW, Gao F.

J Virol. 2011 Oct;85(20):10669-81. doi: 10.1128/JVI.05249-11. Epub 2011 Aug 10.

10.

An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.

Ferrari G, Pollara J, Kozink D, Harms T, Drinker M, Freel S, Moody MA, Alam SM, Tomaras GD, Ochsenbauer C, Kappes JC, Shaw GM, Hoxie JA, Robinson JE, Haynes BF.

J Virol. 2011 Jul;85(14):7029-36. doi: 10.1128/JVI.00171-11. Epub 2011 May 4.

11.

CD8(+)T-cell-mediated control of HIV-1 and SIV infection.

Freel SA, Saunders KO, Tomaras GD.

Immunol Res. 2011 Apr;49(1-3):135-46. doi: 10.1007/s12026-010-8177-7. Review.

PMID:
21170741
12.

Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage.

Saunders KO, Ward-Caviness C, Schutte RJ, Freel SA, Overman RG, Thielman NM, Cunningham CK, Kepler TB, Tomaras GD.

Cell Immunol. 2011;266(2):154-64. doi: 10.1016/j.cellimm.2010.09.011. Epub 2010 Oct 27.

13.

Epigenetic regulation of CD8(+) T-lymphocyte mediated suppression of HIV-1 replication.

Saunders KO, Freel SA, Overman RG, Cunningham CK, Tomaras GD.

Virology. 2010 Sep 15;405(1):234-42. doi: 10.1016/j.virol.2010.06.001. Epub 2010 Jul 1.

14.

Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination.

Freel SA, Lamoreaux L, Chattopadhyay PK, Saunders K, Zarkowsky D, Overman RG, Ochsenbauer C, Edmonds TG, Kappes JC, Cunningham CK, Denny TN, Weinhold KJ, Ferrari G, Haynes BF, Koup RA, Graham BS, Roederer M, Tomaras GD.

J Virol. 2010 May;84(10):4998-5006. doi: 10.1128/JVI.00138-10. Epub 2010 Mar 3.

15.

Heterobiaryl human immunodeficiency virus entry inhibitors.

Lu RJ, Tucker JA, Pickens J, Ma YA, Zinevitch T, Kirichenko O, Konoplev V, Kuznetsova S, Sviridov S, Brahmachary E, Khasanov A, Mikel C, Yang Y, Liu C, Wang J, Freel S, Fisher S, Sullivan A, Zhou J, Stanfield-Oakley S, Baker B, Sailstad J, Greenberg M, Bolognesi D, Bray B, Koszalka B, Jeffs P, Jeffries C, Chucholowski A, Sexton C.

J Med Chem. 2009 Jul 23;52(14):4481-7. doi: 10.1021/jm900330x.

PMID:
19534463
16.

Design and synthesis of human immunodeficiency virus entry inhibitors: sulfonamide as an isostere for the alpha-ketoamide group.

Lu RJ, Tucker JA, Zinevitch T, Kirichenko O, Konoplev V, Kuznetsova S, Sviridov S, Pickens J, Tandel S, Brahmachary E, Yang Y, Wang J, Freel S, Fisher S, Sullivan A, Zhou J, Stanfield-Oakley S, Greenberg M, Bolognesi D, Bray B, Koszalka B, Jeffs P, Khasanov A, Ma YA, Jeffries C, Liu C, Proskurina T, Zhu T, Chucholowski A, Li R, Sexton C.

J Med Chem. 2007 Dec 27;50(26):6535-44. Epub 2007 Dec 4.

PMID:
18052117
17.

Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent activity against enfuvirtide-resistant virus.

Dwyer JJ, Wilson KL, Davison DK, Freel SA, Seedorff JE, Wring SA, Tvermoes NA, Matthews TJ, Greenberg ML, Delmedico MK.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12772-7. Epub 2007 Jul 19.

18.

An inexpensive gel electrophoresis-based polymerase chain reaction method for quantifying mRNA levels.

Bradford WD, Cahoon L, Freel SR, Hoopes LL, Eckdahl TT.

Cell Biol Educ. 2005 Summer;4(2):157-68.

19.

Envelope diversity, coreceptor usage and syncytium-inducing phenotype of HIV-1 variants in saliva and blood during primary infection.

Freel SA, Fiscus SA, Pilcher CD, Menezes P, Giner J, Patrick E, Lennox JL, Hicks CB, Eron JJ Jr, Shugars DC.

AIDS. 2003 Sep 26;17(14):2025-33.

PMID:
14502005
20.

Hyper-excretion of human immunodeficiency virus type 1 RNA in saliva.

Shugars DC, Patton LL, Freel SA, Gray LR, Vollmer RT, Eron JJ Jr, Fiscus SA.

J Dent Res. 2001 Feb;80(2):414-20.

PMID:
11332524
21.

Characterization of human immunodeficiency virus type 1 in saliva and blood plasma by V3-specific heteroduplex tracking assay and genotype analyses.

Freel SA, Williams JM, Nelson JA, Patton LL, Fiscus SA, Swanstrom R, Shugars DC.

J Virol. 2001 May;75(10):4936-40.

22.

Endogenous salivary inhibitors of human immunodeficiency virus.

Shugars DC, Alexander AL, Fu K, Freel SA.

Arch Oral Biol. 1999 Jun;44(6):445-53. Review.

PMID:
10401522

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