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Items: 1 to 50 of 302

1.

Authentication analysis of MT-4 cells distributed by the NIH AIDS Reagent Program.

Fernandez MV, Delviks-Frankenberry KA, Scheiblin DA, Happel C, Pathak VK, Freed EO.

J Virol. 2019 Sep 25. pii: JVI.01390-19. doi: 10.1128/JVI.01390-19. [Epub ahead of print]

PMID:
31554688
2.

Genomic tagging of endogenous human ESCRT-I complex preserves ESCRT-mediated membrane-remodeling functions.

Hoffman HK, Fernandez MV, Groves NS, Freed EO, van Engelenburg SB.

J Biol Chem. 2019 Sep 13. pii: jbc.RA119.009372. doi: 10.1074/jbc.RA119.009372. [Epub ahead of print]

3.

Analysis of HIV-1 Matrix-Envelope Cytoplasmic Tail Interactions.

Alfadhli A, Staubus AO, Tedbury PR, Novikova M, Freed EO, Barklis E.

J Virol. 2019 Oct 15;93(21). pii: e01079-19. doi: 10.1128/JVI.01079-19. Print 2019 Nov 1.

PMID:
31375589
4.

The autophagy protein ATG9A promotes HIV-1 infectivity.

Mailler E, Waheed AA, Park SY, Gershlick DC, Freed EO, Bonifacino JS.

Retrovirology. 2019 Jul 3;16(1):18. doi: 10.1186/s12977-019-0480-3.

5.

Heavy metal protease takes a tiki torch to HIV assembly.

O'Doherty U, Freed EO.

Nat Immunol. 2019 Jun;20(6):668-669. doi: 10.1038/s41590-019-0387-0. No abstract available.

PMID:
31061529
6.

Multiple Roles of HIV-1 Capsid during the Virus Replication Cycle.

Novikova M, Zhang Y, Freed EO, Peng K.

Virol Sin. 2019 Apr;34(2):119-134. doi: 10.1007/s12250-019-00095-3. Epub 2019 Apr 26. Review.

7.

Mutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycle.

Van Duyne R, Kuo LS, Pham P, Fujii K, Freed EO.

Proc Natl Acad Sci U S A. 2019 Apr 30;116(18):9040-9049. doi: 10.1073/pnas.1820333116. Epub 2019 Apr 11.

8.

Inactivation of the uptake hydrogenase in the purple non-sulfur photosynthetic bacterium Rubrivivax gelatinosus CBS enables a biological water-gas shift platform for H2 production.

Eckert CA, Freed E, Wawrousek K, Smolinski S, Yu J, Maness PC.

J Ind Microbiol Biotechnol. 2019 Jul;46(7):993-1002. doi: 10.1007/s10295-019-02173-7. Epub 2019 Apr 9.

PMID:
30968274
9.

TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins.

Li M, Waheed AA, Yu J, Zeng C, Chen HY, Zheng YM, Feizpour A, Reinhard BM, Gummuluru S, Lin S, Freed EO, Liu SL.

Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5705-5714. doi: 10.1073/pnas.1819475116. Epub 2019 Mar 6.

10.

Resistance to Second-Generation HIV-1 Maturation Inhibitors.

Urano E, Timilsina U, Kaplan JA, Ablan S, Ghimire D, Pham P, Kuruppu N, Mandt R, Durell SR, Nitz TJ, Martin DE, Wild CT, Gaur R, Freed EO.

J Virol. 2019 Mar 5;93(6). pii: e02017-18. doi: 10.1128/JVI.02017-18. Print 2019 Mar 15.

11.

Myosin-X is essential to the intercellular spread of HIV-1 Nef through tunneling nanotubes.

Uhl J, Gujarathi S, Waheed AA, Gordon A, Freed EO, Gousset K.

J Cell Commun Signal. 2019 Jun;13(2):209-224. doi: 10.1007/s12079-018-0493-z. Epub 2018 Nov 15.

12.

Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.

Souquet B, Freed E, Berto A, Andric V, Audugé N, Reina-San-Martin B, Lacy E, Doye V.

Cell Rep. 2018 Nov 13;25(7):1994. doi: 10.1016/j.celrep.2018.11.012. No abstract available.

13.

Meeting Review: 2018 International Workshop on Structure and Function of the Lentiviral gp41 Cytoplasmic Tail.

Fernandez MV, Freed EO.

Viruses. 2018 Nov 7;10(11). pii: E613. doi: 10.3390/v10110613.

14.

Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation.

Novikova M, Adams LJ, Fontana J, Gres AT, Balasubramaniam M, Winkler DC, Kudchodkar SB, Soheilian F, Sarafianos SG, Steven AC, Freed EO.

MBio. 2018 Oct 16;9(5). pii: e01567-18. doi: 10.1128/mBio.01567-18.

15.

HIV-1 packs in PACSIN2 for cell-to-cell spread.

Van Duyne R, Freed EO.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):6885-6887. doi: 10.1073/pnas.1808821115. Epub 2018 Jun 20. No abstract available.

16.

Nup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.

Souquet B, Freed E, Berto A, Andric V, Audugé N, Reina-San-Martin B, Lacy E, Doye V.

Cell Rep. 2018 May 22;23(8):2443-2454. doi: 10.1016/j.celrep.2018.04.070. Erratum in: Cell Rep. 2018 Nov 13;25(7):1994.

17.

Building a genome engineering toolbox in nonmodel prokaryotic microbes.

Freed E, Fenster J, Smolinski SL, Walker J, Henard CA, Gill R, Eckert CA.

Biotechnol Bioeng. 2018 Sep;115(9):2120-2138. doi: 10.1002/bit.26727. Epub 2018 May 29. Review.

PMID:
29750332
18.

Single molecule fate of HIV-1 envelope reveals late-stage viral lattice incorporation.

Buttler CA, Pezeshkian N, Fernandez MV, Aaron J, Norman S, Freed EO, van Engelenburg SB.

Nat Commun. 2018 May 10;9(1):1861. doi: 10.1038/s41467-018-04220-w.

19.

High-Mannose But Not Complex-Type Glycosylation of Tetherin Is Required for Restriction of HIV-1 Release.

Waheed AA, Gitzen A, Swiderski M, Freed EO.

Viruses. 2018 Jan 5;10(1). pii: E26. doi: 10.3390/v10010026.

20.

Comprehension in Proficient Readers: The Nature of Individual Variation.

Freed EM, Hamilton ST, Long DL.

J Mem Lang. 2017 Dec;97:135-153. doi: 10.1016/j.jml.2017.07.008. Epub 2017 Aug 25.

21.

Quenching protein dynamics interferes with HIV capsid maturation.

Wang M, Quinn CM, Perilla JR, Zhang H, Shirra R Jr, Hou G, Byeon IJ, Suiter CL, Ablan S, Urano E, Nitz TJ, Aiken C, Freed EO, Zhang P, Schulten K, Gronenborn AM, Polenova T.

Nat Commun. 2017 Nov 24;8(1):1779. doi: 10.1038/s41467-017-01856-y.

22.

Intracellular Reassociation of RNA-DNA Hybrids that Activates RNAi in HIV-Infected Cells.

Martins AN, Ke W, Jawahar V, Striplin M, Striplin C, Freed EO, Afonin KA.

Methods Mol Biol. 2017;1632:269-283. doi: 10.1007/978-1-4939-7138-1_18.

PMID:
28730446
23.

A Consensus View of ESCRT-Mediated Human Immunodeficiency Virus Type 1 Abscission.

Lippincott-Schwartz J, Freed EO, van Engelenburg SB.

Annu Rev Virol. 2017 Sep 29;4(1):309-325. doi: 10.1146/annurev-virology-101416-041840. Epub 2017 Jul 17. Review.

PMID:
28715971
24.

"Expand and Click": A New Method for Labeling HIV-1 Envelope Glycoproteins.

Fernandez MV, Freed EO.

Cell Chem Biol. 2017 May 18;24(5):548-550. doi: 10.1016/j.chembiol.2017.05.006.

25.

Word-Decoding Skill Interacts With Working Memory Capacity to Influence Inference Generation During Reading.

Hamilton S, Freed E, Long DL.

Read Res Q. 2016 Oct-Dec;51(4):391-402. Epub 2016 May 9.

26.

A Triazinone Derivative Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity.

Urano E, Miyauchi K, Kojima Y, Hamatake M, Ablan SD, Fudo S, Freed EO, Hoshino T, Komano J.

ChemMedChem. 2016 Oct 19;11(20):2320-2326. doi: 10.1002/cmdc.201600375. Epub 2016 Sep 16.

PMID:
27634404
27.

Getting IN on Viral RNA Condensation and Virion Maturation.

Freed EO.

Cell. 2016 Aug 25;166(5):1082-1083. doi: 10.1016/j.cell.2016.08.013.

28.

Identification of potent maturation inhibitors against HIV-1 clade C.

Timilsina U, Ghimire D, Timalsina B, Nitz TJ, Wild CT, Freed EO, Gaur R.

Sci Rep. 2016 Jun 6;6:27403. doi: 10.1038/srep27403.

29.

The Vpu-interacting Protein SGTA Regulates Expression of a Non-glycosylated Tetherin Species.

Waheed AA, MacDonald S, Khan M, Mounts M, Swiderski M, Xu Y, Ye Y, Freed EO.

Sci Rep. 2016 Apr 22;6:24934. doi: 10.1038/srep24934.

30.

Trimer Enhancement Mutation Effects on HIV-1 Matrix Protein Binding Activities.

Alfadhli A, Mack A, Ritchie C, Cylinder I, Harper L, Tedbury PR, Freed EO, Barklis E.

J Virol. 2016 May 27;90(12):5657-5664. doi: 10.1128/JVI.00509-16. Print 2016 Jun 15.

31.

Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein.

Mercredi PY, Bucca N, Loeliger B, Gaines CR, Mehta M, Bhargava P, Tedbury PR, Charlier L, Floquet N, Muriaux D, Favard C, Sanders CR, Freed EO, Marchant J, Summers MF.

J Mol Biol. 2016 Apr 24;428(8):1637-55. doi: 10.1016/j.jmb.2016.03.005. Epub 2016 Mar 16.

32.

The Use of Minimal RNA Toeholds to Trigger the Activation of Multiple Functionalities.

Afonin KA, Viard M, Tedbury P, Bindewald E, Parlea L, Howington M, Valdman M, Johns-Boehme A, Brainerd C, Freed EO, Shapiro BA.

Nano Lett. 2016 Mar 9;16(3):1746-53. doi: 10.1021/acs.nanolett.5b04676. Epub 2016 Feb 29.

33.

Biochemical evidence of a role for matrix trimerization in HIV-1 envelope glycoprotein incorporation.

Tedbury PR, Novikova M, Ablan SD, Freed EO.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E182-90. doi: 10.1073/pnas.1516618113. Epub 2015 Dec 28.

34.

Identification of an HIV-1 Mutation in Spacer Peptide 1 That Stabilizes the Immature CA-SP1 Lattice.

Fontana J, Keller PW, Urano E, Ablan SD, Steven AC, Freed EO.

J Virol. 2015 Nov 4;90(2):972-8. doi: 10.1128/JVI.02204-15. Print 2016 Jan 15.

35.

Elucidation of the Molecular Mechanism Driving Duplication of the HIV-1 PTAP Late Domain.

Martins AN, Waheed AA, Ablan SD, Huang W, Newton A, Petropoulos CJ, Brindeiro RD, Freed EO.

J Virol. 2015 Oct 28;90(2):768-79. doi: 10.1128/JVI.01640-15. Print 2016 Jan 15.

36.

Alkyl Amine Bevirimat Derivatives Are Potent and Broadly Active HIV-1 Maturation Inhibitors.

Urano E, Ablan SD, Mandt R, Pauly GT, Sigano DM, Schneider JP, Martin DE, Nitz TJ, Wild CT, Freed EO.

Antimicrob Agents Chemother. 2015 Oct 19;60(1):190-7. doi: 10.1128/AAC.02121-15. Print 2016 Jan.

37.

Genome-Wide Tuning of Protein Expression Levels to Rapidly Engineer Microbial Traits.

Freed EF, Winkler JD, Weiss SJ, Garst AD, Mutalik VK, Arkin AP, Knight R, Gill RT.

ACS Synth Biol. 2015 Nov 20;4(11):1244-53. doi: 10.1021/acssynbio.5b00133. Epub 2015 Nov 5.

PMID:
26478262
38.

IFITM Proteins Restrict HIV-1 Infection by Antagonizing the Envelope Glycoprotein.

Yu J, Li M, Wilkins J, Ding S, Swartz TH, Esposito AM, Zheng YM, Freed EO, Liang C, Chen BK, Liu SL.

Cell Rep. 2015 Oct 6;13(1):145-156. doi: 10.1016/j.celrep.2015.08.055. Epub 2015 Sep 17.

39.

Phosphoketolase pathway engineering for carbon-efficient biocatalysis.

Henard CA, Freed EF, Guarnieri MT.

Curr Opin Biotechnol. 2015 Dec;36:183-8. doi: 10.1016/j.copbio.2015.08.018. Epub 2015 Sep 8. Review.

PMID:
26360872
40.

HIV-1 assembly, release and maturation.

Freed EO.

Nat Rev Microbiol. 2015 Aug;13(8):484-96. doi: 10.1038/nrmicro3490. Epub 2015 Jun 29. Review.

PMID:
26119571
41.

NMR structure of the myristylated feline immunodeficiency virus matrix protein.

Brown LA, Cox C, Baptiste J, Summers H, Button R, Bahlow K, Spurrier V, Kyser J, Luttge BG, Kuo L, Freed EO, Summers MF.

Viruses. 2015 Apr 30;7(5):2210-29. doi: 10.3390/v7052210.

42.

Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate.

Gerber PP, Cabrini M, Jancic C, Paoletti L, Banchio C, von Bilderling C, Sigaut L, Pietrasanta LI, Duette G, Freed EO, Basile Gde S, Moita CF, Moita LF, Amigorena S, Benaroch P, Geffner J, Ostrowski M.

J Cell Biol. 2015 May 11;209(3):435-52. doi: 10.1083/jcb.201409082. Epub 2015 May 4.

43.

Bacterial Recombineering: Genome Engineering via Phage-Based Homologous Recombination.

Pines G, Freed EF, Winkler JD, Gill RT.

ACS Synth Biol. 2015 Nov 20;4(11):1176-85. doi: 10.1021/acssynbio.5b00009. Epub 2015 Apr 27. Review.

PMID:
25856528
44.

HIV-1 gag: an emerging target for antiretroviral therapy.

Tedbury PR, Freed EO.

Curr Top Microbiol Immunol. 2015;389:171-201. doi: 10.1007/82_2015_436. Review.

PMID:
25731773
45.

Announcing the 2015 viruses Young Investigator Prize and Graduate Student/Postdoctoral Fellow Travel awards.

Freed EO.

Viruses. 2015 Feb 12;7(2):707-8. doi: 10.3390/v7020707. No abstract available.

46.

Elucidating the mechanism by which compensatory mutations rescue an HIV-1 matrix mutant defective for gag membrane targeting and envelope glycoprotein incorporation.

Tedbury PR, Mercredi PY, Gaines CR, Summers MF, Freed EO.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1413-1427. doi: 10.1016/j.jmb.2015.01.018. Epub 2015 Feb 7.

47.

The cytoplasmic tail of retroviral envelope glycoproteins.

Tedbury PR, Freed EO.

Prog Mol Biol Transl Sci. 2015;129:253-84. doi: 10.1016/bs.pmbts.2014.10.009. Epub 2014 Dec 1. Review.

PMID:
25595807
48.

In COS cells Vpu can both stabilize tetherin expression and counteract its antiviral activity.

Waheed AA, Kuruppu ND, Felton KL, D'Souza D, Freed EO.

PLoS One. 2014 Oct 31;9(10):e111628. doi: 10.1371/journal.pone.0111628. eCollection 2014.

49.

HIV-1 Vpu accessory protein induces caspase-mediated cleavage of IRF3 transcription factor.

Park SY, Waheed AA, Zhang ZR, Freed EO, Bonifacino JS.

J Biol Chem. 2014 Dec 19;289(51):35102-10. doi: 10.1074/jbc.M114.597062. Epub 2014 Oct 28.

50.

Multifunctional RNA nanoparticles.

Afonin KA, Viard M, Koyfman AY, Martins AN, Kasprzak WK, Panigaj M, Desai R, Santhanam A, Grabow WW, Jaeger L, Heldman E, Reiser J, Chiu W, Freed EO, Shapiro BA.

Nano Lett. 2014 Oct 8;14(10):5662-71. doi: 10.1021/nl502385k. Epub 2014 Sep 30.

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