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The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.
Joyce CW, Amar MJ, Lambert G, Vaisman BL, Paigen B, Najib-Fruchart J, Hoyt RF Jr, Neufeld ED, Remaley AT, Fredrickson DS, Brewer HB Jr, Santamarina-Fojo S.
Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):407-12. Epub 2001 Dec 18.
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The first twenty-five years after Asilomar.
Fredrickson DS.
Perspect Biol Med. 2001 Spring;44(2):170-82. No abstract available.
Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter.
Santamarina-Fojo S, Peterson K, Knapper C, Qiu Y, Freeman L, Cheng JF, Osorio J, Remaley A, Yang XP, Haudenschild C, Prades C, Chimini G, Blackmon E, Francois T, Duverger N, Rubin EM, Rosier M, Denèfle P, Fredrickson DS, Brewer HB Jr.
Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7987-92. Erratum in: Proc Natl Acad Sci U S A 2002 Jan 22;99(2):1098.
Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original Tangier disease kindred.
Remaley AT, Rust S, Rosier M, Knapper C, Naudin L, Broccardo C, Peterson KM, Koch C, Arnould I, Prades C, Duverger N, Funke H, Assman G, Dinger M, Dean M, Chimini G, Santamarina-Fojo S, Fredrickson DS, Denefle P, Brewer HB Jr.
Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12685-90.
James Augustine Shannon (9 August 1904-20 May 1994).
Proc Am Philos Soc. 1996;140(1):105-13. No abstract available.
10th Anniversary Colloquium. Medicine, public health, and environment.
Cook-Deegan R, Fredrickson DS, Joseph SC, Rall DP.
Issues Sci Technol. 1994 Fall;11(1):68-74. No abstract available.
Phenotyping. On reaching base camp (1950-1975).
Circulation. 1993 Apr;87(4 Suppl):III1-15.
The heart in Tangier disease. Severe coronary atherosclerosis with near absence of high-density lipoprotein cholesterol.
Mautner SL, Sanchez JA, Rader DJ, Mautner GC, Ferrans VJ, Fredrickson DS, Brewer HB Jr, Roberts WC.
Am J Clin Pathol. 1992 Aug;98(2):191-8.
NIH: a century of science for health. Challenge of change in biology.
Nature. 1987 Oct 22-28;329(6141):686-7. No abstract available.
On the cultivation of virtue.
Mayo Clin Proc. 1983 Oct;58(10):660-2. No abstract available.
"Venice' is not sinking (the water is rising). Some views on biomedical research.
JAMA. 1982 Jun 11;247(22):3072-5. No abstract available.
Communal resources, community responsibilities.
Clin Res. 1981 Sep;29(3):239-47. No abstract available.
Is there a federal philosophy about academic medicine.
Bull N Y Acad Med. 1981 Jul-Aug;57(6):454-69. No abstract available.
Federally supported human nutrition research, training, and education.
Fredrickson DS, Bertrand A.
Am J Clin Nutr. 1981 May;34(5):957-8. No abstract available.
Biomedical research in the 1980s.
N Engl J Med. 1981 Feb 26;304(9):509-17. No abstract available.
NIH tackles cost accounting issues.
US Med. 1981 Jan 15;17(2):65-6. No abstract available.
A conversation with Donald Sharp Fredrickson, MD, Director of the National Institutes of Health: an exclusive journal profile/interview. Interview by Blaine Taylor.
Md State Med J. 1979 Oct;28(10):61-73. No abstract available.
National Conference on Clinical Trials Methodology: welcoming remarks.
Clin Pharmacol Ther. 1979 May;25(5 Pt 2):630-1. No abstract available.
An overview statement on the National Conference on Health Research Principles.
Clin Res. 1979 Apr;27(2):98-100. No abstract available.
NIH placed accent on health research.
US Med. 1979 Jan 15;15(2):43-6. No abstract available.
The National Institutes of Health yesterday, today, and tomorrow.
Public Health Rep. 1978 Nov-Dec;93(6):642-7. No abstract available.
Tangier disease: one explanation of lipid storage.
Herbert PN, Forte T, Heinen RJ, Fredrickson DS.
N Engl J Med. 1978 Sep 7;299(10):519-21.
Biochemical studies in a patient with a Tangier syndrome.
Yao JK, Herbert PN, Fredrickson DS, Ellefson RD, Heinen RJ, Forte T, Dyck PJ.
J Neuropathol Exp Neurol. 1978 Mar-Apr;37(2):138-54.
Abnormal concentration and anomalous distribution of apolipoprotein A-I in Tangier disease.
Henderson LO, Herbert PN, Fredrickson DS, Heinen RJ, Easterling JC.
Metabolism. 1978 Feb;27(2):165-74.
Properties of the plasma very low and low density lipoproteins in Tangier disease.
Heinen RJ, Herbert PN, Fredrickson DS.
J Clin Invest. 1978 Jan;61(1):120-32.
The public governance of science.
Man Med. 1978;3(2):77-88. No abstract available.
Health and the search for new knowledge.
Daedalus. 1977 Winter:159-70. No abstract available.
Isolation and characterization of an abnormal high density lipoprotein in Tangier Diesase.
Assmann G, Herbert PN, Fredrickson DS, Forte T.
J Clin Invest. 1977 Jul;60(1):242-52.
Aesculapian merry-go-round.
Trans Assoc Am Physicians. 1977;90:59-73. No abstract available.
The government role in biomedical research.
Fed Proc. 1976 Dec;35(14):2538-40. No abstract available.
The search for the Omphalos.
R I Med J. 1976 Oct;59(10):454-6, 470-1. No abstract available.
Recombinant DNA guidelines: environmental impact statement.
Science. 1976 Sep 24;193(4259):1192-4. No abstract available.
Lipid, glucose, and insulin interrelationships in normal, prediabetic, and chemical diabetic subjects.
Kyner JL, Levy RI, Soeldner JS, Gleason RE, Fredrickson DS.
J Lab Clin Med. 1976 Sep;88(3):345-58.
[Behavior of the lipid pattern and electrophoretic lipid levels in children with hepatitis A].
Fredrickson DS, Leevy CM, Tamir J.
Minerva Pediatr. 1976 Mar 31;28(11):701-2. Italian. No abstract available.
The visible internists.
Bull Am Coll Physicians. 1976 Mar;17(3):6-9. No abstract available.
Beta-sitosterolemia and xanthomatosis.
Shulman RS, Bhattacharyya AK, Connor WE, Fredrickson DS.
N Engl J Med. 1976 Feb 26;294(9):482-3. No abstract available.
Research fellowships.
Clin Res. 1976 Jan;24(1):24-6. No abstract available.
Human experimentation.
Fredrickson DS, et al.
Science. 1975 Jun 13;188(4193):1062. No abstract available.
The biochemical, clinical, and genetic features of type III hyperlipoproteinemia.
Morganroth J, Levy RI, Fredrickson DS.
Ann Intern Med. 1975 Feb;82(2):158-74.
Type III hyperlipoproteinemia: an analysis of two contemporary definitions.
Fredrickson DS, Morganroth J, Levy RI.
Ann Intern Med. 1975 Feb;82(2):150-7.
It's time to be practical.
Circulation. 1975 Feb;51(2):209-11. No abstract available.
Thf complete amino acid sequence of C-I (apoLp-Ser), an apolipoprotein from human very low density lipoproteins.
Shulman RS, Herbert PN, Wehrly K, Fredrickson DS.
J Biol Chem. 1975 Jan 10;250(1):182-90.
Structural and compositional changes attending the ultracentrifugation of very low density lipoproteins.
Herbert PN, Forte TM, Shulman RS, La Piana MJ, Gong EL, Levy RI, Fredrickson DS, Nichols AV.
Prep Biochem. 1975;5(2):93-129.
Accumulation of oxygenated steryl esters in Wolman's disease.
Assmann G, Fredrickson DS, Sloan HR, Fales HM, Highet RJ.
J Lipid Res. 1975 Jan;16(1):28-38.
The pathology of Tangier disease. A light and electron microscopic study.
Ferrans VJ, Fredrickson DS.
Am J Pathol. 1975 Jan;78(1):101-58.
Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia.
Krauss RM, Levy RI, Fredrickson DS.
J Clin Invest. 1974 Nov;54(5):1107-24.
Isolation and alignment of the tryptic peptides of alanine apolipoprotein, an apolipoprotein from human plasma very low density lipoproteins.
Shulman RS, Herbert PN, Fredrickson DS, Wehrly K, Brewer HB Jr.
J Biol Chem. 1974 Aug 10;249(15):4969-74. No abstract available.
Familial hypercholesterolemia (one form of familial type II hyperlipoproteinemia). A study of its biochemical, genetic and clinical presentation in childhood.
Kwiterovich PO Jr, Fredrickson DS, Levy RI.
J Clin Invest. 1974 May;53(5):1237-49.
Resting levels of blood fibrinolysis in hyperlipoproteinemia.
Brakman P, Astrup T, Levy RI, Fredrickson DS.
J Appl Physiol. 1974 Apr;36(4):430-3. No abstract available.
Coronary artery disease in 116 kindred with familial type II hyperlipoproteinemia.
Stone NJ, Levy RI, Fredrickson DS, Verter J.
Circulation. 1974 Mar;49(3):476-88. No abstract available.
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