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Items: 1 to 50 of 571

1.

Acute doses of caffeine shift nervous system cell expression profiles toward promotion of neuronal projection growth.

Yu NY, Bieder A, Raman A, Mileti E, Katayama S, Einarsdottir E, Fredholm BB, Falk A, Tapia-Páez I, Daub CO, Kere J.

Sci Rep. 2017 Sep 13;7(1):11458. doi: 10.1038/s41598-017-11574-6.

2.

Adenosine and Sleep.

Lazarus M, Chen JF, Huang ZL, Urade Y, Fredholm BB.

Handb Exp Pharmacol. 2017 Jun 24. doi: 10.1007/164_2017_36. [Epub ahead of print]

PMID:
28646346
3.

Adenosine - from molecular mechanisms to pathophysiology.

Sobrevia L, Fredholm BB.

Mol Aspects Med. 2017 Jun;55:1-3. doi: 10.1016/j.mam.2017.06.003. Epub 2017 Jun 17. No abstract available.

PMID:
28624328
4.

Single Dose Caffeine Protects the Neonatal Mouse Brain against Hypoxia Ischemia.

Winerdal M, Urmaliya V, Winerdal ME, Fredholm BB, Winqvist O, Ådén U.

PLoS One. 2017 Jan 27;12(1):e0170545. doi: 10.1371/journal.pone.0170545. eCollection 2017.

5.

Pharmacological targeting of adenosine receptor signaling.

Peleli M, Fredholm BB, Sobrevia L, Carlström M.

Mol Aspects Med. 2017 Jun;55:4-8. doi: 10.1016/j.mam.2016.12.002. Epub 2017 Jan 12. Review.

PMID:
28088486
6.

Low, but not high, dose caffeine is a readily available probe for adenosine actions.

Fredholm BB, Yang J, Wang Y.

Mol Aspects Med. 2017 Jun;55:20-25. doi: 10.1016/j.mam.2016.11.011. Epub 2016 Nov 30. Review.

PMID:
27915051
7.

Genetic Abrogation of Adenosine A3 Receptor Prevents Uninephrectomy and High Salt-Induced Hypertension.

Yang T, Zollbrecht C, Winerdal ME, Zhuge Z, Zhang XM, Terrando N, Checa A, Sällström J, Wheelock CE, Winqvist O, Harris RA, Larsson E, Persson AE, Fredholm BB, Carlström M.

J Am Heart Assoc. 2016 Jul 18;5(7). pii: e003868. doi: 10.1161/JAHA.116.003868.

8.

Adenosine A1 receptors contribute to immune regulation after neonatal hypoxic ischemic brain injury.

Winerdal M, Winerdal ME, Wang YQ, Fredholm BB, Winqvist O, Ådén U.

Purinergic Signal. 2016 Mar;12(1):89-101. doi: 10.1007/s11302-015-9482-3. Epub 2015 Nov 25.

9.

In adenosine A2B knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver.

Peleli M, Hezel M, Zollbrecht C, Persson AE, Lundberg JO, Weitzberg E, Fredholm BB, Carlström M.

Front Physiol. 2015 Aug 7;6:222. doi: 10.3389/fphys.2015.00222. eCollection 2015.

10.

Abrogation of adenosine A1 receptor signalling improves metabolic regulation in mice by modulating oxidative stress and inflammatory responses.

Yang T, Gao X, Sandberg M, Zollbrecht C, Zhang XM, Hezel M, Liu M, Peleli M, Lai EY, Harris RA, Persson AE, Fredholm BB, Jansson L, Carlström M.

Diabetologia. 2015 Jul;58(7):1610-20. doi: 10.1007/s00125-015-3570-3. Epub 2015 Apr 3.

PMID:
25835725
11.

Adenosine--a physiological or pathophysiological agent?

Fredholm BB.

J Mol Med (Berl). 2014 Mar;92(3):201-6. doi: 10.1007/s00109-013-1101-6. Epub 2013 Dec 22. Review.

PMID:
24362516
12.

Adenosine increases LPS-induced nuclear factor kappa B activation in smooth muscle cells via an intracellular mechanism and modulates it via actions on adenosine receptors.

Yang J, Zheng X, Haugen F, Darè E, Lövdahl C, Schulte G, Fredholm BB, Valen G.

Acta Physiol (Oxf). 2014 Mar;210(3):590-9. doi: 10.1111/apha.12176. Epub 2013 Oct 28.

PMID:
24119187
13.

Inhibition of sodium-linked glucose reabsorption normalizes diabetes-induced glomerular hyperfiltration in conscious adenosine A₁-receptor deficient mice.

Sällström J, Eriksson T, Fredholm BB, Persson AE, Palm F.

Acta Physiol (Oxf). 2014 Feb;210(2):440-5. doi: 10.1111/apha.12152. Epub 2013 Aug 27.

14.

Adenosine receptors as drug targets--what are the challenges?

Chen JF, Eltzschig HK, Fredholm BB.

Nat Rev Drug Discov. 2013 Apr;12(4):265-86. doi: 10.1038/nrd3955. Review.

16.

Improved blood glucose disposal and altered insulin secretion patterns in adenosine A(1) receptor knockout mice.

Yang GK, Fredholm BB, Kieffer TJ, Kwok YN.

Am J Physiol Endocrinol Metab. 2012 Jul 15;303(2):E180-90. doi: 10.1152/ajpendo.00050.2012. Epub 2012 May 1.

17.

Rethinking the purinergic neuron-glia connection.

Fredholm BB.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):5913-4. doi: 10.1073/pnas.1203764109. Epub 2012 Apr 16. No abstract available.

18.

CX3CL1 is neuroprotective in permanent focal cerebral ischemia in rodents.

Cipriani R, Villa P, Chece G, Lauro C, Paladini A, Micotti E, Perego C, De Simoni MG, Fredholm BB, Eusebi F, Limatola C.

J Neurosci. 2011 Nov 9;31(45):16327-35. doi: 10.1523/JNEUROSCI.3611-11.2011.

19.

Adenosine A₁-receptor deficiency diminishes afferent arteriolar and blood pressure responses during nitric oxide inhibition and angiotensin II treatment.

Gao X, Patzak A, Sendeski M, Scheffer PG, Teerlink T, Sällström J, Fredholm BB, Persson AE, Carlström M.

Am J Physiol Regul Integr Comp Physiol. 2011 Dec;301(6):R1669-81. doi: 10.1152/ajpregu.00268.2011. Epub 2011 Oct 5.

20.

Arousal effect of caffeine depends on adenosine A2A receptors in the shell of the nucleus accumbens.

Lazarus M, Shen HY, Cherasse Y, Qu WM, Huang ZL, Bass CE, Winsky-Sommerer R, Semba K, Fredholm BB, Boison D, Hayaishi O, Urade Y, Chen JF.

J Neurosci. 2011 Jul 6;31(27):10067-75. doi: 10.1523/JNEUROSCI.6730-10.2011.

21.

A ketogenic diet suppresses seizures in mice through adenosine A₁ receptors.

Masino SA, Li T, Theofilas P, Sandau US, Ruskin DN, Fredholm BB, Geiger JD, Aronica E, Boison D.

J Clin Invest. 2011 Jul;121(7):2679-83. doi: 10.1172/JCI57813. Epub 2011 Jun 23.

22.

Adenosine and the regulation of metabolism and body temperature.

Fredholm BB, Johansson S, Wang YQ.

Adv Pharmacol. 2011;61:77-94. doi: 10.1016/B978-0-12-385526-8.00003-5. Review.

PMID:
21586356
23.

Adenosine and ATP receptors in the brain.

Burnstock G, Fredholm BB, Verkhratsky A.

Curr Top Med Chem. 2011;11(8):973-1011. Review.

PMID:
21401499
24.

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update.

Fredholm BB, IJzerman AP, Jacobson KA, Linden J, Müller CE.

Pharmacol Rev. 2011 Mar;63(1):1-34. doi: 10.1124/pr.110.003285. Epub 2011 Feb 8. Review.

25.

WITHDRAWN: Involvement of Adenosine Signaling in Controlling the Release of Ghrelin from the Mouse Stomach.

Yang GK, Yip L, Fredholm BB, Kieffer TJ, Kwok YN.

Regul Pept. 2011 Jan 21. [Epub ahead of print]

PMID:
21256874
26.

Involvement of adenosine signaling in controlling the release of ghrelin from the mouse stomach.

Yang GK, Yip L, Fredholm BB, Kieffer TJ, Kwok YN.

J Pharmacol Exp Ther. 2011 Jan;336(1):77-86. doi: 10.1124/jpet.110.171280. Epub 2010 Sep 27.

PMID:
20876230
27.

Fuels for transportation.

Fredholm BB, Nordén B.

Ambio. 2010;39 Suppl 1:31-5.

28.

Notes on the history of caffeine use.

Fredholm BB.

Handb Exp Pharmacol. 2011;(200):1-9. doi: 10.1007/978-3-642-13443-2_1.

PMID:
20859791
29.

Deletion of adenosine A₁ or A(₂A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease.

Xiao D, Cassin JJ, Healy B, Burdett TC, Chen JF, Fredholm BB, Schwarzschild MA.

Brain Res. 2011 Jan 7;1367:310-8. doi: 10.1016/j.brainres.2010.08.099. Epub 2010 Sep 7.

30.

High-protein-induced glomerular hyperfiltration is independent of the tubuloglomerular feedback mechanism and nitric oxide synthases.

Sällström J, Carlström M, Olerud J, Fredholm BB, Kouzmine M, Sandler S, Persson AE.

Am J Physiol Regul Integr Comp Physiol. 2010 Nov;299(5):R1263-8. doi: 10.1152/ajpregu.00649.2009. Epub 2010 Aug 25.

31.

Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.

Li L, Hao JX, Fredholm BB, Schulte G, Wiesenfeld-Hallin Z, Xu XJ.

Neuroscience. 2010 Oct 27;170(3):923-8. doi: 10.1016/j.neuroscience.2010.07.045. Epub 2010 Aug 3.

PMID:
20678550
32.

CX3CL1-induced modulation at CA1 synapses reveals multiple mechanisms of EPSC modulation involving adenosine receptor subtypes.

Piccinin S, Di Angelantonio S, Piccioni A, Volpini R, Cristalli G, Fredholm BB, Limatola C, Eusebi F, Ragozzino D.

J Neuroimmunol. 2010 Jul 27;224(1-2):85-92. doi: 10.1016/j.jneuroim.2010.05.012. Epub 2010 Jun 8.

PMID:
20570369
33.

The birth and postnatal development of purinergic signalling.

Burnstock G, Fredholm BB, North RA, Verkhratsky A.

Acta Physiol (Oxf). 2010 Jun;199(2):93-147. doi: 10.1111/j.1748-1716.2010.02114.x. Epub 2010 Mar 24. Review.

PMID:
20345419
34.

Adenosine A(1) receptors contribute to mitochondria vulnerability to pro-oxidant stressors.

Minelli A, Grottelli S, Corazzi L, Bellezza I, Rambotti MG, Emiliani C, Fredholm BB.

Mitochondrion. 2010 Jun;10(4):369-79. doi: 10.1016/j.mito.2010.03.004. Epub 2010 Mar 15.

PMID:
20230919
35.

Adenosine A1 receptors and microglial cells mediate CX3CL1-induced protection of hippocampal neurons against Glu-induced death.

Lauro C, Cipriani R, Catalano M, Trettel F, Chece G, Brusadin V, Antonilli L, van Rooijen N, Eusebi F, Fredholm BB, Limatola C.

Neuropsychopharmacology. 2010 Jun;35(7):1550-9. doi: 10.1038/npp.2010.26. Epub 2010 Mar 3.

36.

Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function.

Kara FM, Chitu V, Sloane J, Axelrod M, Fredholm BB, Stanley ER, Cronstein BN.

FASEB J. 2010 Jul;24(7):2325-33. doi: 10.1096/fj.09-147447. Epub 2010 Feb 24.

37.

Caffeine reverses antinociception by oxcarbazepine by inhibition of adenosine A1 receptors: insights using knockout mice.

Sawynok J, Reid AR, Fredholm BB.

Neurosci Lett. 2010 Apr 12;473(3):178-81. doi: 10.1016/j.neulet.2010.02.028. Epub 2010 Feb 20.

PMID:
20176083
38.

Adenosine receptors as drug targets.

Fredholm BB.

Exp Cell Res. 2010 May 1;316(8):1284-8. doi: 10.1016/j.yexcr.2010.02.004. Epub 2010 Feb 11. Review.

39.

Adenosine A(1) receptors and vascular reactivity.

Wang Y, Yang JN, Arner A, Boels PJ, Fredholm BB.

Acta Physiol (Oxf). 2010 Jun;199(2):211-20. doi: 10.1111/j.1748-1716.2010.02093.x. Epub 2010 Feb 2.

PMID:
20132147
40.

Adenosine A(3) receptors regulate heart rate, motor activity and body temperature.

Yang JN, Wang Y, Garcia-Roves PM, Björnholm M, Fredholm BB.

Acta Physiol (Oxf). 2010 Jun;199(2):221-30. doi: 10.1111/j.1748-1716.2010.02091.x. Epub 2010 Feb 1.

41.
42.

Adenosine signaling and function in glial cells.

Boison D, Chen JF, Fredholm BB.

Cell Death Differ. 2010 Jul;17(7):1071-82. doi: 10.1038/cdd.2009.131. Epub 2009 Sep 18. Review.

43.

LTP impairment by fractalkine/CX3CL1 in mouse hippocampus is mediated through the activity of adenosine receptor type 3 (A3R).

Maggi L, Trettel F, Scianni M, Bertollini C, Eusebi F, Fredholm BB, Limatola C.

J Neuroimmunol. 2009 Oct 30;215(1-2):36-42. doi: 10.1016/j.jneuroim.2009.07.016. Epub 2009 Aug 26.

PMID:
19709758
44.

Absence of adenosine A1 receptors unmasks pulses of insulin release and prolongs those of glucagon and somatostatin.

Salehi A, Parandeh F, Fredholm BB, Grapengiesser E, Hellman B.

Life Sci. 2009 Sep 9;85(11-12):470-6. doi: 10.1016/j.lfs.2009.08.001. Epub 2009 Aug 12.

PMID:
19682463
45.

Adenosine, adenosine A 2A antagonists, and Parkinson's disease.

Jenner P, Mori A, Hauser R, Morelli M, Fredholm BB, Chen JF.

Parkinsonism Relat Disord. 2009 Jul;15(6):406-13. doi: 10.1016/j.parkreldis.2008.12.006. Epub 2009 May 15. Review.

PMID:
19446490
46.

Uncovering multiple molecular targets for caffeine using a drug target validation strategy combining A 2A receptor knockout mice with microarray profiling.

Yu L, Coelho JE, Zhang X, Fu Y, Tillman A, Karaoz U, Fredholm BB, Weng Z, Chen JF.

Physiol Genomics. 2009 May 13;37(3):199-210. doi: 10.1152/physiolgenomics.90353.2008. Epub 2009 Mar 3.

47.

A(1) and A(3) adenosine receptors alter glutathione status in an organ-specific manner and influence the changes after inhibition of gamma-glutamylcysteine ligase.

Conte C, Grottelli S, Prudenzi E, Bellezza I, Fredholm BB, Minelli A.

Free Radic Res. 2009 Mar;43(3):304-11. doi: 10.1080/10715760802712616.

PMID:
19229670
48.

Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine.

Yang JN, Chen JF, Fredholm BB.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1141-9. doi: 10.1152/ajpheart.00754.2008. Epub 2009 Feb 13.

49.

Adenosine Receptors: The Contributions by John W. Daly.

Fredholm BB, Jacobson KA.

Heterocycles. 2009;79(1):73-83.

50.

Perinatal caffeine, acting on maternal adenosine A(1) receptors, causes long-lasting behavioral changes in mouse offspring.

Björklund O, Kahlström J, Salmi P, Fredholm BB.

PLoS One. 2008;3(12):e3977. doi: 10.1371/journal.pone.0003977. Epub 2008 Dec 18.

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