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Items: 14


A gratuitous β-Lactamase inducer uncovers hidden active site dynamics of the Staphylococcus aureus BlaR1 sensor domain.

Frederick TE, Peng JW.

PLoS One. 2018 May 17;13(5):e0197241. doi: 10.1371/journal.pone.0197241. eCollection 2018.


Electron Cryo-microscopy Structure of Ebola Virus Nucleoprotein Reveals a Mechanism for Nucleocapsid-like Assembly.

Su Z, Wu C, Shi L, Luthra P, Pintilie GD, Johnson B, Porter JR, Ge P, Chen M, Liu G, Frederick TE, Binning JM, Bowman GR, Zhou ZH, Basler CF, Gross ML, Leung DW, Chiu W, Amarasinghe GK.

Cell. 2018 Feb 22;172(5):966-978.e12. doi: 10.1016/j.cell.2018.02.009.


Prediction of New Stabilizing Mutations Based on Mechanistic Insights from Markov State Models.

Zimmerman MI, Hart KM, Sibbald CA, Frederick TE, Jimah JR, Knoverek CR, Tolia NH, Bowman GR.

ACS Cent Sci. 2017 Dec 27;3(12):1311-1321. doi: 10.1021/acscentsci.7b00465. Epub 2017 Nov 21.


Repurposing Hsp90 inhibitors as antibiotics targeting histidine kinases.

Vo CD, Shebert HL, Zikovich S, Dryer RA, Huang TP, Moran LJ, Cho J, Wassarman DR, Falahee BE, Young PD, Gu GH, Heinl JF, Hammond JW, Jackvony TN, Frederick TE, Blair JA.

Bioorg Med Chem Lett. 2017 Dec 1;27(23):5235-5244. doi: 10.1016/j.bmcl.2017.10.036. Epub 2017 Oct 19.


Endogenous retinoid X receptor ligands in mouse hematopoietic cells.

Niu H, Fujiwara H, di Martino O, Hadwiger G, Frederick TE, Menéndez-Gutiérrez MP, Ricote M, Bowman GR, Welch JS.

Sci Signal. 2017 Oct 31;10(503). pii: eaan1011. doi: 10.1126/scisignal.aan1011.


Designing small molecules to target cryptic pockets yields both positive and negative allosteric modulators.

Hart KM, Moeder KE, Ho CMW, Zimmerman MI, Frederick TE, Bowman GR.

PLoS One. 2017 Jun 1;12(6):e0178678. doi: 10.1371/journal.pone.0178678. eCollection 2017.


Investigation of signal transduction routes within the sensor/transducer protein BlaR1 of Staphylococcus aureus.

Staude MW, Frederick TE, Natarajan SV, Wilson BD, Tanner CE, Ruggiero ST, Mobashery S, Peng JW.

Biochemistry. 2015 Mar 3;54(8):1600-10. doi: 10.1021/bi501463k. Epub 2015 Feb 18.


Revealing cell-surface intramolecular interactions in the BlaR1 protein of methicillin-resistant Staphylococcus aureus by NMR spectroscopy.

Frederick TE, Wilson BD, Cha J, Mobashery S, Peng JW.

Biochemistry. 2014 Jan 14;53(1):10-2. doi: 10.1021/bi401552j. Epub 2013 Dec 24.


Evaluation of a library outreach program to research labs.

Brandenburg MD, Doss A, Frederick TE.

Med Ref Serv Q. 2010 Jul;29(3):249-59. doi: 10.1080/02763869.2010.494489.


Effects of the endosomal lipid bis(monoacylglycero)phosphate on the thermotropic properties of DPPC: A 2H NMR and spin label EPR study.

Frederick TE, Goff PC, Mair CE, Farver RS, Long JR, Fanucci GE.

Chem Phys Lipids. 2010 Sep;163(7):703-11. doi: 10.1016/j.chemphyslip.2010.06.002. Epub 2010 Jun 19.


Bis(monoacylglycero)phosphate and ganglioside GM1 spontaneously form small homogeneous vesicles at specific concentrations.

Chebukati JN, Goff PC, Frederick TE, Fanucci GE.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):509-14. doi: 10.1016/j.bbrc.2010.02.180. Epub 2010 Mar 3.


Bis(monoacylglycero)phosphate forms stable small lamellar vesicle structures: insights into vesicular body formation in endosomes.

Frederick TE, Chebukati JN, Mair CE, Goff PC, Fanucci GE.

Biophys J. 2009 Mar 4;96(5):1847-55. doi: 10.1016/j.bpj.2008.12.3892.


Topiramate in older patients with partial-onset seizures: a pilot double-blind, dose-comparison study.

Ramsay RE, Uthman B, Pryor FM, Rowan AJ, Bainbridge J, Spitz M, Sirven JI, Frederick TE.

Epilepsia. 2008 Jul;49(7):1180-5. doi: 10.1111/j.1528-1167.2008.01584.x.


Carbamazepine-induced rash.

Frederick TE.

Neurology. 1991 Aug;41(8):1328. No abstract available.


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